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Items: 29


Software for Dosage Individualization of Voriconazole: a Prospective Clinical Study.

Hope W, Johnstone G, Cicconi S, Felton T, Goodwin J, Whalley S, Santoyo-Castelazo A, Ramos-Martin V, Lestner J, Credidio L, Dane A, Carr DF, Pirmohamed M, Salim R, Neely M.

Antimicrob Agents Chemother. 2019 Mar 27;63(4). pii: e02353-18. doi: 10.1128/AAC.02353-18. Print 2019 Apr.


Correction for Stott et al., "Population Pharmacokinetic Model and Meta-analysis of Outcomes of Amphotericin B Deoxycholate Use in Adults with Cryptococcal Meningitis".

Stott KE, Beardsley J, Whalley S, Mukasa Kibengo F, Mai NTH, Tùng NLN, Cuc NTK, Kolamunnage-Dona R, Hope W, Day J.

Antimicrob Agents Chemother. 2018 Nov 26;62(12). pii: e02249-18. doi: 10.1128/AAC.02249-18. Print 2018 Dec. No abstract available.


Development, validation and application of a novel HPLC-MS/MS method for the quantification of atorvastatin, bisoprolol and clopidogrel in a large cardiovascular patient cohort.

Turner RM, Fontana V, Bayliss M, Whalley S, Santoyo Castelazo A, Pirmohamed M.

J Pharm Biomed Anal. 2018 Sep 10;159:272-281. doi: 10.1016/j.jpba.2018.06.062. Epub 2018 Jul 3.


Population Pharmacokinetic Model and Meta-analysis of Outcomes of Amphotericin B Deoxycholate Use in Adults with Cryptococcal Meningitis.

Stott KE, Beardsley J, Whalley S, Kibengo FM, Mai NTH, Tùng NLN, Cuc NTK, Kolamunnage-Dona R, Hope W, Day J.

Antimicrob Agents Chemother. 2018 Jun 26;62(7). pii: e02526-17. doi: 10.1128/AAC.02526-17. Print 2018 Jul. Erratum in: Antimicrob Agents Chemother. 2018 Nov 26;62(12):.


Pharmacodynamics of Voriconazole for Invasive Pulmonary Scedosporiosis.

Box H, Negri C, Livermore J, Whalley S, Johnson A, McEntee L, Alastruey-Izquierdo A, Meis JF, Thornton C, Hope W.

Antimicrob Agents Chemother. 2018 Apr 26;62(5). pii: e02516-17. doi: 10.1128/AAC.02516-17. Print 2018 May.


Repurposing and Reformulation of the Antiparasitic Agent Flubendazole for Treatment of Cryptococcal Meningoencephalitis, a Neglected Fungal Disease.

Nixon GL, McEntee L, Johnson A, Farrington N, Whalley S, Livermore J, Natal C, Washbourn G, Bibby J, Berry N, Lestner J, Truong M, Owen A, Lalloo D, Charles I, Hope W.

Antimicrob Agents Chemother. 2018 Mar 27;62(4). pii: e01909-17. doi: 10.1128/AAC.01909-17. Print 2018 Apr.


Pharmacodynamics of the Novel Antifungal Agent F901318 for Acute Sinopulmonary Aspergillosis Caused by Aspergillus flavus.

Negri CE, Johnson A, McEntee L, Box H, Whalley S, Schwartz JA, Ramos-Martín V, Livermore J, Kolamunnage-Dona R, Colombo AL, Hope WW.

J Infect Dis. 2018 Mar 13;217(7):1118-1127. doi: 10.1093/infdis/jix479. Erratum in: J Infect Dis. 2018 Apr 20;:.


Pharmacodynamics of the Orotomides against Aspergillus fumigatus: New Opportunities for Treatment of Multidrug-Resistant Fungal Disease.

Hope WW, McEntee L, Livermore J, Whalley S, Johnson A, Farrington N, Kolamunnage-Dona R, Schwartz J, Kennedy A, Law D, Birch M, Rex JH.

MBio. 2017 Aug 22;8(4). pii: e01157-17. doi: 10.1128/mBio.01157-17.


Fluconazole Pharmacokinetics in Galleria mellonella Larvae and Performance Evaluation of a Bioassay Compared to Liquid Chromatography-Tandem Mass Spectrometry for Hemolymph Specimens.

Astvad KMT, Meletiadis J, Whalley S, Arendrup MC.

Antimicrob Agents Chemother. 2017 Sep 22;61(10). pii: e00895-17. doi: 10.1128/AAC.00895-17. Print 2017 Oct.


Experimental Models of Short Courses of Liposomal Amphotericin B for Induction Therapy for Cryptococcal Meningitis.

Lestner J, McEntee L, Johnson A, Livermore J, Whalley S, Schwartz J, Perfect JR, Harrison T, Hope W.

Antimicrob Agents Chemother. 2017 May 24;61(6). pii: e00090-17. doi: 10.1128/AAC.00090-17. Print 2017 Jun.


Use of read-across to simplify the toxicological assessment of a complex mixture of lysimeter leachate metabolites on the basis of chemical similarity and ADME behavior.

Hand LH, Richardson K, Hadfield ST, Whalley S, Rawlinson P, Booth ED.

Regul Toxicol Pharmacol. 2017 Feb;83:109-116. doi: 10.1016/j.yrtph.2016.11.019. Epub 2016 Nov 18.


Pharmacodynamics of Aerosolized Fosfomycin and Amikacin against Resistant Clinical Isolates of Pseudomonas aeruginosa and Klebsiella pneumoniae in a Hollow-Fiber Infection Model: Experimental Basis for Combination Therapy.

Sime FB, Johnson A, Whalley S, Santoyo-Castelazo A, Montgomery AB, Walters KA, Lipman J, Hope WW, Roberts JA.

Antimicrob Agents Chemother. 2016 Dec 27;61(1). pii: e01763-16. doi: 10.1128/AAC.01763-16. Print 2017 Jan.


Pharmacodynamics of vancomycin for CoNS infection: experimental basis for optimal use of vancomycin in neonates.

Ramos-Martín V, Johnson A, Livermore J, McEntee L, Goodwin J, Whalley S, Docobo-Pérez F, Felton TW, Zhao W, Jacqz-Aigrain E, Sharland M, Turner MA, Hope WW.

J Antimicrob Chemother. 2016 Apr;71(4):992-1002. doi: 10.1093/jac/dkv451. Epub 2016 Jan 10.


Display glass for low-loss and high-density optical interconnects in electro-optical circuit boards with eight optical layers.

Brusberg L, Whalley S, Herbst C, Schröder H.

Opt Express. 2015 Dec 14;23(25):32528-40. doi: 10.1364/OE.23.032528.


Pharmacodynamics of Isavuconazole in a Dynamic In Vitro Model of Invasive Pulmonary Aspergillosis.

Box H, Livermore J, Johnson A, McEntee L, Felton TW, Whalley S, Goodwin J, Hope WW.

Antimicrob Agents Chemother. 2015 Oct 26;60(1):278-87. doi: 10.1128/AAC.01364-15. Print 2016 Jan.


Pharmacodynamics of fosfomycin: insights into clinical use for antimicrobial resistance.

Docobo-Pérez F, Drusano GL, Johnson A, Goodwin J, Whalley S, Ramos-Martín V, Ballestero-Tellez M, Rodriguez-Martinez JM, Conejo MC, van Guilder M, Rodríguez-Baño J, Pascual A, Hope WW.

Antimicrob Agents Chemother. 2015 Sep;59(9):5602-10. doi: 10.1128/AAC.00752-15. Epub 2015 Jun 29.


Pulmonary penetration of piperacillin and tazobactam in critically ill patients.

Felton TW, McCalman K, Malagon I, Isalska B, Whalley S, Goodwin J, Bentley AM, Hope WW.

Clin Pharmacol Ther. 2014 Oct;96(4):438-48. doi: 10.1038/clpt.2014.131. Epub 2014 Jun 13.


Predictions of metabolic drug-drug interactions using physiologically based modelling: Two cytochrome P450 3A4 substrates coadministered with ketoconazole or verapamil.

Perdaems N, Blasco H, Vinson C, Chenel M, Whalley S, Cazade F, Bouzom F.

Clin Pharmacokinet. 2010 Apr;49(4):239-58. doi: 10.2165/11318130-000000000-00000.


Hepatology outpatient service provision in secondary care: a study of liver disease incidence and resource costs.

Whalley S, Puvanachandra P, Desai A, Kennedy H.

Clin Med (Lond). 2007 Apr;7(2):119-24.


Evolution of hepatitis B virus during primary infection in humans: transient generation of cytotoxic T-cell mutants.

Whalley SA, Brown D, Webster GJ, Jacobs R, Reignat S, Bertoletti A, Teo CG, Emery V, Dusheiko GM.

Gastroenterology. 2004 Oct;127(4):1131-8.


Identification of chemosensory sensilla activating antennular grooming behavior in the Caribbean spiny lobster, Panulirus argus.

Wroblewska J, Whalley S, Fischetti M, Daniel PC.

Chem Senses. 2002 Nov;27(9):769-78.


A rapid real-time quantitative polymerase chain reaction for hepatitis B virus.

Brechtbuehl K, Whalley SA, Dusheiko GM, Saunders NA.

J Virol Methods. 2001 Apr;93(1-2):105-13.


Predictors of a favorable response to alpha interferon therapy for hepatitis C.

Barnes E, Webster G, Whalley S, Dusheiko G.

Clin Liver Dis. 1999 Nov;3(4):775-91. Review.


Kinetics of acute hepatitis B virus infection in humans.

Whalley SA, Murray JM, Brown D, Webster GJ, Emery VC, Dusheiko GM, Perelson AS.

J Exp Med. 2001 Apr 2;193(7):847-54.


Monitoring the emergence of hepatitis B virus polymerase gene variants during lamivudine therapy using the LightCycler.

Whalley SA, Brown D, Teo CG, Dusheiko GM, Saunders NA.

J Clin Microbiol. 2001 Apr;39(4):1456-9.


Incubation phase of acute hepatitis B in man: dynamic of cellular immune mechanisms.

Webster GJ, Reignat S, Maini MK, Whalley SA, Ogg GS, King A, Brown D, Amlot PL, Williams R, Vergani D, Dusheiko GM, Bertoletti A.

Hepatology. 2000 Nov;32(5):1117-24.


Molecular epidemiology of a large outbreak of hepatitis B linked to autohaemotherapy.

Webster GJ, Hallett R, Whalley SA, Meltzer M, Balogun K, Brown D, Farrington CP, Sharma S, Hamilton G, Farrow SC, Ramsay ME, Teo CG, Dusheiko GM.

Lancet. 2000 Jul 29;356(9227):379-84.


The science, economics, and effectiveness of combination therapy for hepatitis C.

Dusheiko G, Barnes E, Webster G, Whalley S.

Gut. 2000 Aug;47(2):159-61. No abstract available.

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