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Items: 28

1.

Pre-clinical pharmacology of AZD3965, a selective inhibitor of MCT1: DLBCL, NHL and Burkitt's lymphoma anti-tumor activity.

Curtis NJ, Mooney L, Hopcroft L, Michopoulos F, Whalley N, Zhong H, Murray C, Logie A, Revill M, Byth KF, Benjamin AD, Firth MA, Green S, Smith PD, Critchlow SE.

Oncotarget. 2017 May 25;8(41):69219-69236. doi: 10.18632/oncotarget.18215. eCollection 2017 Sep 19.

2.

Pyruvate dehydrogenase kinase 4 exhibits a novel role in the activation of mutant KRAS, regulating cell growth in lung and colorectal tumour cells.

Trinidad AG, Whalley N, Rowlinson R, Delpuech O, Dudley P, Rooney C, Critchlow SE.

Oncogene. 2017 Nov 2;36(44):6164-6176. doi: 10.1038/onc.2017.224. Epub 2017 Jul 10.

3.

Targeting KRAS-dependent tumors with AZD4785, a high-affinity therapeutic antisense oligonucleotide inhibitor of KRAS.

Ross SJ, Revenko AS, Hanson LL, Ellston R, Staniszewska A, Whalley N, Pandey SK, Revill M, Rooney C, Buckett LK, Klein SK, Hudson K, Monia BP, Zinda M, Blakey DC, Lyne PD, Macleod AR.

Sci Transl Med. 2017 Jun 14;9(394). pii: eaal5253. doi: 10.1126/scitranslmed.aal5253. Erratum in: Sci Transl Med. 2017 Jul 26;9(400):.

PMID:
28615361
4.

Targeted Metabolic Profiling of the Tg197 Mouse Model Reveals Itaconic Acid as a Marker of Rheumatoid Arthritis.

Michopoulos F, Karagianni N, Whalley NM, Firth MA, Nikolaou C, Wilson ID, Critchlow SE, Kollias G, Theodoridis GA.

J Proteome Res. 2016 Dec 2;15(12):4579-4590. Epub 2016 Oct 28.

5.

Clinically Viable Gene Expression Assays with Potential for Predicting Benefit from MEK Inhibitors.

Brant R, Sharpe A, Liptrot T, Dry JR, Harrington EA, Barrett JC, Whalley N, Womack C, Smith P, Hodgson DR.

Clin Cancer Res. 2017 Mar 15;23(6):1471-1480. doi: 10.1158/1078-0432.CCR-16-0021. Epub 2016 Oct 12.

6.

Can local recurrence of a sacral chordoma be treated by further surgery?

Xie C, Whalley N, Adasonla K, Grimer R, Jeys L.

Bone Joint J. 2015 May;97-B(5):711-5. doi: 10.1302/0301-620X.97B5.35131.

PMID:
25922468
7.

Targeted profiling of polar intracellular metabolites using ion-pair-high performance liquid chromatography and -ultra high performance liquid chromatography coupled to tandem mass spectrometry: applications to serum, urine and tissue extracts.

Michopoulos F, Whalley N, Theodoridis G, Wilson ID, Dunkley TP, Critchlow SE.

J Chromatogr A. 2014 Jul 4;1349:60-8. doi: 10.1016/j.chroma.2014.05.019. Epub 2014 May 12.

PMID:
24861786
8.

Islets of Langerhans from prohormone convertase-2 knockout mice show α-cell hyperplasia and tumorigenesis with elevated α-cell neogenesis.

Jones HB, Reens J, Brocklehurst SR, Betts CJ, Bickerton S, Bigley AL, Jenkins RP, Whalley NM, Morgan D, Smith DM.

Int J Exp Pathol. 2014 Feb;95(1):29-48. doi: 10.1111/iep.12066.

9.

Processing of proglucagon to GLP-1 in pancreatic α-cells: is this a paracrine mechanism enabling GLP-1 to act on β-cells?

Whalley NM, Pritchard LE, Smith DM, White A.

J Endocrinol. 2011 Oct;211(1):99-106. doi: 10.1530/JOE-11-0094. Epub 2011 Jul 27.

PMID:
21795304
10.

An evaluation of 2-deoxy-2-[18F]fluoro-D-glucose and 3'-deoxy-3'-[18F]-fluorothymidine uptake in human tumor xenograft models.

Keen H, Pichler B, Kukuk D, Duchamp O, Raguin O, Shannon A, Whalley N, Jacobs V, Bales J, Gingles N, Ricketts SA, Wedge SR.

Mol Imaging Biol. 2012 Jun;14(3):355-65. doi: 10.1007/s11307-011-0504-4.

PMID:
21761255
11.

Cystine: a promoter of the growth and aggregation of calcium oxalate crystals in normal undiluted human urine.

Martins MC, Meyers AA, Whalley NA, Rodgers AL.

J Urol. 2002 Jan;167(1):317-21.

PMID:
11743349
12.

Lithogenic risk factors in normal black volunteers, and black and white recurrent stone formers.

Whalley NA, Martins MC, Van Dyk RC, Meyers AM.

BJU Int. 1999 Aug;84(3):243-8.

PMID:
10468714
13.

Lithogenic risk factors in the urine of black and white subjects.

Whalley NA, Moraes MF, Shar TG, Pretorius SS, Meyers AM.

Br J Urol. 1998 Dec;82(6):785-90.

PMID:
9883212
14.

Indapamide (Natrilix): the agent of choice in the treatment of recurrent renal calculi associated with idiopathic hypercalciuria.

Martins MC, Meyers AM, Whalley NA, Margolius LP, Buys ME.

Br J Urol. 1996 Aug;78(2):176-80.

PMID:
8813907
15.
16.

Chronic laxative abusers with pseudo-idiopathic oedema and autonomous pseudo-Bartter's syndrome. A spectrum of metabolic madness, or new lights on an old disease?

Meyers AM, Feldman C, Sonnekus MI, Ninin DT, Margolius LP, Whalley NA.

S Afr Med J. 1990 Dec 1;78(11):631-6.

PMID:
2251604
17.

Vertebral osteoclastoma with spinal cord compression.

WHALLEY N.

Br J Surg. 1958 Jan;45(192):364-72. No abstract available.

PMID:
13536330
18.

An unusually large dermoic cyst of the scalp.

WHALLEY N.

Br J Dermatol. 1952 May;64(5):194-5. No abstract available.

PMID:
14925277
19.

Abscess formation in a pituitary adenoma.

WHALLEY N.

J Neurol Neurosurg Psychiatry. 1952 Feb;15(1):66-7. No abstract available.

20.

Prolonged compression of the brain resulting from an extradural haemorrhage.

ROWBOTHAM GF, WHALLEY N.

J Neurol Neurosurg Psychiatry. 1952 Feb;15(1):64-5. No abstract available.

21.

Management of the closed head injury.

WHALLEY N.

Med Illus. 1950 Jun;4(6):281-7. No abstract available.

PMID:
15423135
22.

Ruptured congenital aneurysm of anterior cerebral artery; report of a case with successful surgical removal.

WHALLEY N.

J Neurol Neurosurg Psychiatry. 1949 Nov;12(4):322-4, illust. No abstract available.

23.

The problem of the localized surface intracranial haemorrhage causing compression of the brain.

WHALLEY N.

Br J Surg. 1949 Oct;37(146):212-9, illust. No abstract available.

PMID:
15395090
24.

Low backache, sciatic pain and the herniated nucleus pulposus.

ROWBOTHAM GF, WHALLEY N.

Practitioner. 1948 Mar;160(957):212-20. No abstract available.

PMID:
18909812
25.

Acute subdural haematoma amenable to surgical treatment.

WHALLEY N.

Lancet. 1948 Feb 7;1(6493):213. No abstract available.

PMID:
18921098
26.

A series of wounds of the head from the battle front of North-west Europe.

ROWBOTHAM GF, WHALLEY N.

Br J Surg. 1947;55(Suppl 1):87-90. No abstract available.

PMID:
18918453
27.

Paget's disease of atlas and axis.

WHALLEY N.

J Neurol Neurosurg Psychiatry. 1946 Jul;9(3):84-6. No abstract available.

28.

Traumatic aneurysm of the common carotid artery associated with massive infarction of the brain.

WHALLEY N.

Br J Surg. 1946 Apr;34:400. No abstract available.

PMID:
20996588

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