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Pitfalls of molecular diagnostic testing for Coxiella burnetii DNA on throat swabs.

Buijs SB, Hermans MHA, Agni N, de Vries MC, Hoepelman AIM, Oosterheert JJ, Wever PC.

J Microbiol Methods. 2019 Jul;162:16-20. doi: 10.1016/j.mimet.2019.05.006. Epub 2019 May 14.


[John McCrae, physician and poet of "In Flanders Fields"].

Hermens WAJJ, Wever PC.

Ned Tijdschr Geneeskd. 2018 Oct 26;162. pii: D3215. Dutch.


Response to: Q fever mortality in the Netherlands, why so high?

van Roeden SE, Wever PC, Oosterheert JJ.

Clin Microbiol Infect. 2019 Mar 23. pii: S1198-743X(19)30106-5. doi: 10.1016/j.cmi.2019.03.004. [Epub ahead of print] No abstract available.


The value of the neutrophil-lymphocyte count ratio in the diagnosis of sepsis in patients admitted to the Intensive Care Unit: A retrospective cohort study.

Westerdijk K, Simons KS, Zegers M, Wever PC, Pickkers P, de Jager CPC.

PLoS One. 2019 Feb 27;14(2):e0212861. doi: 10.1371/journal.pone.0212861. eCollection 2019.


Coxiella burnetii in non-Hodgkin lymphoma tissue samples: Innocent until proven otherwise?

van Roeden SE, Hermans MHA, Nooijen PTGA, Herbers A, Bleeker-Rovers CP, Hoepelman AIM, Oosterheert JJ, Wever PC.

Immunobiology. 2019 Mar;224(2):254-261. doi: 10.1016/j.imbio.2018.11.012. Epub 2018 Dec 5.


Genetic variations in innate immunity genes affect response to Coxiella burnetii and are associated with susceptibility to chronic Q fever.

Jansen AFM, Schoffelen T, Bleeker-Rovers CP, Wever PC, Jaeger M, Oosting M, Adriaans A, Joosten LAB, Netea MG, van Deuren M, van de Vosse E.

Clin Microbiol Infect. 2019 May;25(5):631.e11-631.e15. doi: 10.1016/j.cmi.2018.08.011. Epub 2019 Jan 4.


Chronic Q fever-related complications and mortality: data from a nationwide cohort.

van Roeden SE, Wever PC, Kampschreur LM, Gruteke P, van der Hoek W, Hoepelman AIM, Bleeker-Rovers CP, Oosterheert JJ.

Clin Microbiol Infect. 2018 Dec 10. pii: S1198-743X(18)30766-3. doi: 10.1016/j.cmi.2018.11.023. [Epub ahead of print]


Soluble mannose receptor levels in blood correlate to disease severity in patients with community-acquired pneumonia.

Loonen AJM, Leijtens S, Serin O, Hilbink M, Wever PC, van den Brule AJC, Toonen EJM.

Immunol Lett. 2019 Feb;206:28-32. doi: 10.1016/j.imlet.2018.12.001. Epub 2018 Dec 4.


Chronic Q fever: patient and treatment-related factors influencing long-term quality of life.

van Roeden SE, Reukers DFM, van Jaarsveld CHM, Kampschreur LM, Hoepelman IM, Wever PC, Bleeker-Rovers CP, Oosterheert JJ.

QJM. 2018 Nov 1;111(11):791-797. doi: 10.1093/qjmed/hcy171.


Viable Coxiella burnetii Induces Differential Cytokine Responses in Chronic Q Fever Patients Compared to Heat-Killed Coxiella burnetii.

Jansen AFM, Dinkla A, Roest HJ, Bleeker-Rovers CP, Schoffelen T, Joosten LAB, Wever PC, van Deuren M, Koets AP.

Infect Immun. 2018 Sep 21;86(10). pii: e00333-18. doi: 10.1128/IAI.00333-18. Print 2018 Oct.


Primary and secondary arterial fistulas during chronic Q fever.

Karhof S, van Roeden SE, Oosterheert JJ, Bleeker-Rovers CP, Renders NHM, de Borst GJ, Kampschreur LM, Hoepelman AIM, Koning OHJ, Wever PC.

J Vasc Surg. 2018 Dec;68(6):1906-1913.e1. doi: 10.1016/j.jvs.2018.01.044.


Exposure to Coxiella burnetii and risk of non-Hodgkin lymphoma: a retrospective population-based analysis in the Netherlands.

van Roeden SE, van Houwelingen F, Donkers CMJ, Hogewoning SJ, de Lange MMA, van der Hoek W, Kampschreur LM, Bonten MJM, Hoepelman AIM, Bleeker-Rovers CP, Wever PC, Oosterheert JJ.

Lancet Haematol. 2018 May;5(5):e211-e219. doi: 10.1016/S2352-3026(18)30038-3. Epub 2018 Apr 9.


The effect of measuring serum doxycycline concentrations on clinical outcomes during treatment of chronic Q fever.

van Roeden SE, Bleeker-Rovers CP, Kampschreur LM, de Regt MJA, Vermeulen Windsant A, Hoepelman AIM, Wever PC, Oosterheert JJ.

J Antimicrob Chemother. 2018 Apr 1;73(4):1068-1076. doi: 10.1093/jac/dkx487.


Treatment of Chronic Q Fever: Clinical Efficacy and Toxicity of Antibiotic Regimens.

van Roeden SE, Bleeker-Rovers CP, de Regt MJA, Kampschreur LM, Hoepelman AIM, Wever PC, Oosterheert JJ.

Clin Infect Dis. 2018 Feb 10;66(5):719-726. doi: 10.1093/cid/cix886.


Case report: Coxiella burnetii vascular infection and lymphoma in the Netherlands.

van Roeden SE, Melenotte C, Hermans MHA, Sinnige HAM, Nooijen PTGA, Audoly G, Hoepelman AIM, Oosterheert JJ, Raoult D, Wever PC.

Infection. 2018 Feb;46(1):131-134. doi: 10.1007/s15010-017-1061-9. Epub 2017 Aug 24.


The Value of 18F-FDG PET/CT in Diagnosis and During Follow-up in 273 Patients with Chronic Q Fever.

Kouijzer IJE, Kampschreur LM, Wever PC, Hoekstra C, van Kasteren MEE, de Jager-Leclercq MGL, Nabuurs-Franssen MH, Wegdam-Blans MCA, Ammerlaan HSM, Buijs J, Geus-Oei LF, Oyen WJG, Bleeker-Rovers CP.

J Nucl Med. 2018 Jan;59(1):127-133. doi: 10.2967/jnumed.117.192492. Epub 2017 May 25.


Disseminated Mycobacterium abscessus infection in a peritoneal dialysis patient.

Mooren VHJF, Bleeker MWP, van Ingen J, Hermans MHA, Wever PC.

IDCases. 2017 May 4;9:6-7. doi: 10.1016/j.idcr.2017.05.001. eCollection 2017.


Outbreak of NDM-1-Producing Klebsiella pneumoniae in a Dutch Hospital, with Interspecies Transfer of the Resistance Plasmid and Unexpected Occurrence in Unrelated Health Care Centers.

Bosch T, Lutgens SPM, Hermans MHA, Wever PC, Schneeberger PM, Renders NHM, Leenders ACAP, Kluytmans JAJW, Schoffelen A, Notermans D, Witteveen S, Bathoorn E, Schouls LM.

J Clin Microbiol. 2017 Aug;55(8):2380-2390. doi: 10.1128/JCM.00535-17. Epub 2017 May 17.


High pneumococcal DNA load, procalcitonin and suPAR levels correlate to severe disease development in patients with pneumococcal pneumonia.

Loonen AJM, Kesarsing C, Kusters R, Hilbink M, Wever PC, van den Brule AJC.

Eur J Clin Microbiol Infect Dis. 2017 Sep;36(9):1541-1547. doi: 10.1007/s10096-017-2963-2. Epub 2017 Mar 29.


Involvement of matrix metalloproteinases in chronic Q fever.

Jansen AFM, Schoffelen T, Textoris J, Mege JL, Bleeker-Rovers CP, Roest HIJ, Wever PC, Joosten LAB, Netea MG, van de Vosse E, van Deuren M.

Clin Microbiol Infect. 2017 Jul;23(7):487.e7-487.e13. doi: 10.1016/j.cmi.2017.01.022. Epub 2017 Feb 4.


No 10 Stationary Hospital and the chapel ward at Saint-Omer, France, 1914-18.

Wever PC.

BMJ. 2016 Dec 12;355:i6509. doi: 10.1136/bmj.i6509. No abstract available.


Value of 18F-FDG PET/CT in diagnosing chronic Q fever in patients with central vascular disease.

Hagenaars JC, Wever PC, Vlake AW, Renders NH, van Petersen AS, Hilbink M, de Jager-Leclercq MG, Moll FL, Koning OH, Hoekstra CJ.

Neth J Med. 2016 Aug;74(7):301-8.


Sputum Induction in Children Is Feasible and Useful in a Bustling General Hospital Practice.

Bart IY, Mourits M, van Gent R, van Leuken MH, Hilbink M, Warris A, Wever PC, de Vries E.

Glob Pediatr Health. 2016 Mar 4;3:2333794X16636504. doi: 10.1177/2333794X16636504. eCollection 2016.


The First World War years of Sydney Domville Rowland: an early case of possible laboratory-acquired meningococcal disease.

Wever PC, Hodges AJ.

J R Army Med Corps. 2016 Aug;162(4):310-5. doi: 10.1136/jramc-2016-000634. Epub 2016 Apr 15.


Capnocytophaga canimorsus meningitis diagnosed by 16S rRNA PCR.

Beernink TM, Wever PC, Hermans MH, Bartholomeus MG.

Pract Neurol. 2016 Apr;16(2):136-8. doi: 10.1136/practneurol-2015-001166. Epub 2015 Nov 25.


Vascular complications and surgical interventions after world's largest Q fever outbreak.

Broos PP, Hagenaars JC, Kampschreur LM, Wever PC, Bleeker-Rovers CP, Koning OH, Teijink JA, Wegdam-Blans MC.

J Vasc Surg. 2015 Nov;62(5):1273-80. doi: 10.1016/j.jvs.2015.06.217. Epub 2015 Sep 10.


Genetic variation in TLR10 is not associated with chronic Q fever, despite the inhibitory effect of TLR10 on Coxiella burnetii-induced cytokines in vitro.

Ammerdorffer A, Stappers MH, Oosting M, Schoffelen T, Hagenaars JC, Bleeker-Rovers CP, Wegdam-Blans MC, Wever PC, Roest HJ, van de Vosse E, Netea MG, Sprong T, Joosten LA.

Cytokine. 2016 Jan;77:196-202. doi: 10.1016/j.cyto.2015.09.005. Epub 2015 Sep 11.


Chronic Q fever diagnosis— consensus guideline versus expert opinion

Kampschreur LM, Wegdam-Blans MC, Wever PC, Renders NH, Delsing CE, Sprong T, van Kasteren ME, Bijlmer H, Notermans D, Oosterheert JJ, Stals FS, Nabuurs-Franssen MH, Bleeker-Rovers CP; Dutch Q Fever Consensus Group.

Emerg Infect Dis. 2015 Jul;21(7):1183-8.


Long-Term Serological Follow-Up of Acute Q-Fever Patients after a Large Epidemic.

Wielders CC, van Loenhout JA, Morroy G, Rietveld A, Notermans DW, Wever PC, Renders NH, Leenders AC, van der Hoek W, Schneeberger PM.

PLoS One. 2015 Jul 10;10(7):e0131848. doi: 10.1371/journal.pone.0131848. eCollection 2015.


Dysregulation of serum gamma interferon levels in vascular chronic Q Fever patients provides insights into disease pathogenesis.

Pennings JL, Kremers MN, Hodemaekers HM, Hagenaars JC, Koning OH, Renders NH, Hermans MH, de Klerk A, Notermans DW, Wever PC, Janssen R.

Clin Vaccine Immunol. 2015 Jun;22(6):664-71. doi: 10.1128/CVI.00078-15. Epub 2015 Apr 29.


[Adrian Stokes and 'trench jaundice'].

Wever PC.

Ned Tijdschr Geneeskd. 2015;159:A8648. Dutch.


Genetic Variation in Pattern Recognition Receptors and Adaptor Proteins Associated With Development of Chronic Q Fever.

Schoffelen T, Ammerdorffer A, Hagenaars JC, Bleeker-Rovers CP, Wegdam-Blans MC, Wever PC, Joosten LA, van der Meer JW, Sprong T, Netea MG, van Deuren M, van de Vosse E.

J Infect Dis. 2015 Sep 1;212(5):818-29. doi: 10.1093/infdis/jiv113. Epub 2015 Feb 26.


Vascular chronic Q fever: quality of life.

Hagenaars JC, Wever PC, Shamelian SO, Van Petersen AS, Hilbink M, Renders NH, De Jager-Leclercq GL, Moll FL, Koning OH.

Epidemiol Infect. 2015 Oct;143(13):2903-9. doi: 10.1017/S0950268814003951. Epub 2015 Jan 22.


The discriminative capacity of soluble Toll-like receptor (sTLR)2 and sTLR4 in inflammatory diseases.

Ten Oever J, Kox M, van de Veerdonk FL, Mothapo KM, Slavcovici A, Jansen TL, Tweehuysen L, Giamarellos-Bourboulis EJ, Schneeberger PM, Wever PC, Stoffels M, Simon A, van der Meer JW, Johnson MD, Kullberg BJ, Pickkers P, Pachot A, Joosten LA, Netea MG.

BMC Immunol. 2014 Nov 19;15:55. doi: 10.1186/s12865-014-0055-y.


Death from 1918 pandemic influenza during the First World War: a perspective from personal and anecdotal evidence.

Wever PC, van Bergen L.

Influenza Other Respir Viruses. 2014 Sep;8(5):538-46. doi: 10.1111/irv.12267. Epub 2014 Jun 27. Review.


Histological characteristics of the abdominal aortic wall in patients with vascular chronic Q fever.

Hagenaars JC, Koning OH, van den Haak RF, Verhoeven BA, Renders NH, Hermans MH, Wever PC, van Suylen RJ.

Int J Exp Pathol. 2014 Aug;95(4):282-9. doi: 10.1111/iep.12086. Epub 2014 Jun 23.


Coxiella burnetii infection (Q fever) in rheumatoid arthritis patients with and without anti-TNFα therapy.

Schoffelen T, Kampschreur LM, van Roeden SE, Wever PC, den Broeder AA, Nabuurs-Franssen MH, Sprong T, Joosten LA, van Riel PL, Oosterheert JJ, van Deuren M, Creemers MC.

Ann Rheum Dis. 2014 Jul;73(7):1436-8. doi: 10.1136/annrheumdis-2014-205455. Epub 2014 May 2. No abstract available.


Estimated prevalence of chronic Q fever among Coxiella burnetii seropositive patients with an abdominal aortic/iliac aneurysm or aorto-iliac reconstruction after a large Dutch Q fever outbreak.

Hagenaars JC, Wever PC, van Petersen AS, Lestrade PJ, de Jager-Leclercq MG, Hermans MH, Moll FL, Koning OH, Renders NH.

J Infect. 2014 Aug;69(2):154-60. doi: 10.1016/j.jinf.2014.03.009. Epub 2014 Mar 16.


Serological follow-up in patients with aorto-iliac disease and evidence of Q fever infection.

Hagenaars JC, Renders NH, van Petersen AS, Shamelian SO, de Jager-Leclercq MG, Moll FL, Wever PC, Koning OH.

Eur J Clin Microbiol Infect Dis. 2014 Aug;33(8):1407-14. doi: 10.1007/s10096-014-2084-0. Epub 2014 Mar 12.


Characteristics of hospitalized acute Q fever patients during a large epidemic, The Netherlands.

Wielders CC, Wuister AM, de Visser VL, de Jager-Leclercq MG, Groot CA, Dijkstra F, van Gageldonk-Lafeber AB, van Leuken JP, Wever PC, van der Hoek W, Schneeberger PM.

PLoS One. 2014 Mar 10;9(3):e91764. doi: 10.1371/journal.pone.0091764. eCollection 2014.


Chronic Q fever in the Netherlands 5 years after the start of the Q fever epidemic: results from the Dutch chronic Q fever database.

Kampschreur LM, Delsing CE, Groenwold RH, Wegdam-Blans MC, Bleeker-Rovers CP, de Jager-Leclercq MG, Hoepelman AI, van Kasteren ME, Buijs J, Renders NH, Nabuurs-Franssen MH, Oosterheert JJ, Wever PC.

J Clin Microbiol. 2014 May;52(5):1637-43. doi: 10.1128/JCM.03221-13. Epub 2014 Mar 5.


Foodborne trematodiasis and Opisthorchis felineus acquired in Italy.

Wunderink HF, Rozemeijer W, Wever PC, Verweij JJ, van Lieshout L.

Emerg Infect Dis. 2014 Jan;20(1):154-5. doi: 10.3201/eid2001.130476. No abstract available. Erratum in: Emerg Infect Dis. 2014 Dec;20(12):2186. Rozemijer, Wouter [corrected to Rozemeijer, Wouter].


Correlations between peripheral blood Coxiella burnetii DNA load, interleukin-6 levels, and C-reactive protein levels in patients with acute Q fever.

Kremers MN, Janssen R, Wielders CC, Kampschreur LM, Schneeberger PM, Netten PM, de Klerk A, Hodemaekers HM, Hermans MH, Notermans DW, Wever PC.

Clin Vaccine Immunol. 2014 Apr;21(4):484-7. doi: 10.1128/CVI.00715-13. Epub 2014 Jan 29.


Biomarkers and molecular analysis to improve bloodstream infection diagnostics in an emergency care unit.

Loonen AJ, de Jager CP, Tosserams J, Kusters R, Hilbink M, Wever PC, van den Brule AJ.

PLoS One. 2014 Jan 27;9(1):e87315. doi: 10.1371/journal.pone.0087315. eCollection 2014.


Two cases with acute abdominal aneurysm and evidence of acute Q fever infection.

Hagenaars JC, Kampschreur LM, de Jager-Leclercq MG, van Petersen AS, Moll FL, Renders NH, Wever PC, Koning OH, Hoornenborg E.

Ann Vasc Surg. 2014 Feb;28(2):494.e1-3. doi: 10.1016/j.avsg.2013.03.022. Epub 2013 Dec 22.


Predominant association of Raoultella bacteremia with diseases of the biliary tract.

de Jong E, Erkens-Hulshof S, van der Velden LB, Voss A, Bosboom R, Hodiamont CJ, Wever PC, Rentenaar RJ, Sturm PD.

Scand J Infect Dis. 2014 Feb;46(2):141-3. doi: 10.3109/00365548.2013.857044. Epub 2013 Dec 11.


Emergence of methicillin resistance and Panton-Valentine leukocidin positivity in hospital- and community-acquired Staphylococcus aureus infections in Beira, Mozambique.

van der Meeren BT, Millard PS, Scacchetti M, Hermans MH, Hilbink M, Concelho TB, Ferro JJ, Wever PC.

Trop Med Int Health. 2014 Feb;19(2):169-76. doi: 10.1111/tmi.12221. Epub 2013 Nov 11.


Antibiotic prophylaxis for high-risk patients with acute Q Fever: no definitive answers yet.

Kampschreur LM, Oosterheert JJ, Wever PC, Bleeker-Rovers CP.

Clin Infect Dis. 2014 Feb;58(3):446-7. doi: 10.1093/cid/cit718. Epub 2013 Nov 5. No abstract available.


The aetiology of community-acquired pneumonia and implications for patient management.

van Gageldonk-Lafeber AB, Wever PC, van der Lubben IM, de Jager CP, Meijer A, de Vries MC, Elberse K, van der Sande MA, van der Hoek W.

Neth J Med. 2013 Oct;71(8):418-25.

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