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Items: 1 to 50 of 495

1.

The authors reply.

Ledbetter D, Aczon M, Wetzel RC.

Pediatr Crit Care Med. 2019 Apr;20(4):399-400. doi: 10.1097/PCC.0000000000001900. No abstract available.

PMID:
30951002
2.

The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2.

Tafur L, Sadian Y, Hanske J, Wetzel R, Weis F, Müller CW.

Elife. 2019 Mar 26;8. pii: e43204. doi: 10.7554/eLife.43204.

3.

Honey-Based Salve and Burdock Leaf Dressings as an Alternative to Surgical Debridement of a Traumatic Wound Eschar.

Schell A, Copp J, Bogie KM, Wetzel R.

Adv Wound Care (New Rochelle). 2019 Mar 1;8(3):101-107. doi: 10.1089/wound.2018.0806. Epub 2019 Mar 5.

4.

Factors associated with the prevalence of neonatal abstinence syndrome in West Virginia.

Rogerson T, Houston A 2nd, Lyman G, Ogden J, Paschall K, Penaranda M, Rios A, Wetzel R, Horzempa J.

J Opioid Manag. 2018 Nov/Dec;14(6):445-452. doi: 10.5055/jom.2018.0477.

PMID:
30629281
5.

Response to Letter to the Editor: Costs and Radiographic Outcomes of Rotational Ankle Fractures Treated by Orthopaedic Surgeons With or Without Trauma Fellowship Training.

Virkus WW, Wetzel RJ, McKinley TO, Sorkin AT, Cheeseman JS, Hill LC, Kempton LB.

J Am Acad Orthop Surg. 2019 Feb 1;27(3):e143-e145. doi: 10.5435/JAAOS-D-18-00509. No abstract available.

PMID:
30320736
6.

Predicting individual physiologically acceptable states at discharge from a pediatric intensive care unit.

Carlin CS, Ho LV, Ledbetter DR, Aczon MD, Wetzel RC.

J Am Med Inform Assoc. 2018 Dec 1;25(12):1600-1607. doi: 10.1093/jamia/ocy122.

PMID:
30295770
7.

Artificial Intelligence: An Inkling of Caution.

Wetzel RC, Aczon M, Ledbetter DR.

Pediatr Crit Care Med. 2018 Oct;19(10):1004-1005. doi: 10.1097/PCC.0000000000001700. No abstract available.

PMID:
30281572
8.

Scapular Body Fracture in the Athlete: A Systematic Review.

Neral M, Knapik DM, Wetzel RJ, Salata MJ, Voos JE.

HSS J. 2018 Oct;14(3):328-332. doi: 10.1007/s11420-018-9624-6. Epub 2018 Aug 13. Review.

PMID:
30258341
9.

Mutational analysis implicates the amyloid fibril as the toxic entity in Huntington's disease.

Drombosky KW, Rode S, Kodali R, Jacob TC, Palladino MJ, Wetzel R.

Neurobiol Dis. 2018 Dec;120:126-138. doi: 10.1016/j.nbd.2018.08.019. Epub 2018 Aug 30.

PMID:
30171891
10.

Low-dose dexmedetomidine as an adjuvant to propofol infusion for children in MRI: A double-cohort study.

Nagoshi M, Reddy S, Bell M, Cresencia A, Margolis R, Wetzel R, Ross P.

Paediatr Anaesth. 2018 Jul;28(7):639-646. doi: 10.1111/pan.13400. Epub 2018 Jun 7.

PMID:
29882298
11.

The Dependence of Machine Learning on Electronic Medical Record Quality.

Ho LV, Ledbetter D, Aczon M, Wetzel R.

AMIA Annu Symp Proc. 2018 Apr 16;2017:883-891. eCollection 2017.

12.

Costs and Radiographic Outcomes of Rotational Ankle Fractures Treated by Orthopaedic Surgeons With or Without Trauma Fellowship Training.

Virkus WW, Wetzel RJ, McKinley TO, Sorkin AT, Cheesman JS, Hill LC, Kempton LB.

J Am Acad Orthop Surg. 2018 Jun 15;26(12):e261-e268. doi: 10.5435/JAAOS-D-16-00687.

PMID:
29787464
13.

An Aggregate Weight-Normalized Thioflavin-T Measurement Scale for Characterizing Polymorphic Amyloids and Assembly Intermediates.

Wetzel R, Chemuru S, Misra P, Kodali R, Mukherjee S, Kar K.

Methods Mol Biol. 2018;1777:121-144. doi: 10.1007/978-1-4939-7811-3_6.

PMID:
29744831
14.

Applying Machine Learning to Pediatric Critical Care Data.

Williams JB, Ghosh D, Wetzel RC.

Pediatr Crit Care Med. 2018 Jul;19(7):599-608. doi: 10.1097/PCC.0000000000001567.

PMID:
29727354
15.

Heterotopic Ossification of the Inferior Pubic Ramus.

Cheng CW, Kim SP, Francis JJ, Wetzel RJ.

J Am Acad Orthop Surg. 2018 Jun 1;26(11):e246-e248. doi: 10.5435/JAAOS-D-17-00101.

PMID:
29697500
16.

Coacervation-Mediated Combinatorial Synthesis of Biomatrices for Stem Cell Culture and Directed Differentiation.

Wieduwild R, Wetzel R, Husman D, Bauer S, El-Sayed I, Duin S, Murawala P, Thomas AK, Wobus M, Bornhäuser M, Zhang Y.

Adv Mater. 2018 May;30(22):e1706100. doi: 10.1002/adma.201706100. Epub 2018 Apr 16.

PMID:
29659062
17.

First Get the Data, Then Do the Science!

Wetzel RC.

Pediatr Crit Care Med. 2018 Apr;19(4):382-383. doi: 10.1097/PCC.0000000000001482. No abstract available.

PMID:
29620713
18.

Molecular mechanism of promoter opening by RNA polymerase III.

Vorländer MK, Khatter H, Wetzel R, Hagen WJH, Müller CW.

Nature. 2018 Jan 17;553(7688):295-300. doi: 10.1038/nature25440.

19.

RAD52 is required for RNA-templated recombination repair in post-mitotic neurons.

Welty S, Teng Y, Liang Z, Zhao W, Sanders LH, Greenamyre JT, Rubio ME, Thathiah A, Kodali R, Wetzel R, Levine AS, Lan L.

J Biol Chem. 2018 Jan 26;293(4):1353-1362. doi: 10.1074/jbc.M117.808402. Epub 2017 Dec 7.

20.

Development and Validation of an Empiric Tool to Predict Favorable Neurologic Outcomes Among PICU Patients.

Gupta P, Rettiganti M, Gossett JM, Daufeldt J, Rice TB, Wetzel RC.

Crit Care Med. 2018 Jan;46(1):108-115. doi: 10.1097/CCM.0000000000002753.

PMID:
28991830
21.

Prevalence and Management of Coracoid Fracture Sustained During Sporting Activities and Time to Return to Sport: A Systematic Review.

Knapik DM, Patel SH, Wetzel RJ, Voos JE.

Am J Sports Med. 2018 Mar;46(3):753-758. doi: 10.1177/0363546517718513. Epub 2017 Aug 7.

PMID:
28783475
22.

Structural insights into transcription initiation by yeast RNA polymerase I.

Sadian Y, Tafur L, Kosinski J, Jakobi AJ, Wetzel R, Buczak K, Hagen WJ, Beck M, Sachse C, Müller CW.

EMBO J. 2017 Sep 15;36(18):2698-2709. doi: 10.15252/embj.201796958. Epub 2017 Jul 24.

23.

Fibril polymorphism affects immobilized non-amyloid flanking domains of huntingtin exon1 rather than its polyglutamine core.

Lin HK, Boatz JC, Krabbendam IE, Kodali R, Hou Z, Wetzel R, Dolga AM, Poirier MA, van der Wel PCA.

Nat Commun. 2017 May 24;8:15462. doi: 10.1038/ncomms15462.

24.

Backbone Engineering within a Latent β-Hairpin Structure to Design Inhibitors of Polyglutamine Amyloid Formation.

Kar K, Baker MA, Lengyel GA, Hoop CL, Kodali R, Byeon IJ, Horne WS, van der Wel PC, Wetzel R.

J Mol Biol. 2017 Jan 20;429(2):308-323. doi: 10.1016/j.jmb.2016.12.010. Epub 2016 Dec 13.

25.

Wide Variation of Surgical Cost in the Treatment of Periarticular Lower Extremity Injuries Between 6 Fellowship-Trained Trauma Surgeons.

Wetzel RJ, Kempton LB, Lee ES, Zlowodzki M, McKinley TO, Virkus WW.

J Orthop Trauma. 2016 Dec;30(12):e377-e383.

PMID:
27870692
26.

Molecular Structures of Transcribing RNA Polymerase I.

Tafur L, Sadian Y, Hoffmann NA, Jakobi AJ, Wetzel R, Hagen WJH, Sachse C, Müller CW.

Mol Cell. 2016 Dec 15;64(6):1135-1143. doi: 10.1016/j.molcel.2016.11.013. Epub 2016 Nov 17.

27.

Mainstream capnography system for nonintubated children in the postanesthesia care unit: Performance with changing flow rates, and a comparison to side stream capnography.

Nagoshi M, Morzov R, Hotz J, Belson P, Matar M, Ross P, Wetzel R.

Paediatr Anaesth. 2016 Dec;26(12):1179-1187. doi: 10.1111/pan.13003. Epub 2016 Sep 24.

PMID:
27663694
28.

Pediatric Intensive Care Databases for Quality Improvement.

Wetzel RC.

J Pediatr Intensive Care. 2016 Sep;5(3):81-88. doi: 10.1055/s-0035-1568146. Epub 2015 Nov 30. Review.

29.

Rapid α-oligomer formation mediated by the Aβ C terminus initiates an amyloid assembly pathway.

Misra P, Kodali R, Chemuru S, Kar K, Wetzel R.

Nat Commun. 2016 Aug 22;7:12419. doi: 10.1038/ncomms12419.

30.

Association of Freestanding Children's Hospitals With Outcomes in Children With Critical Illness.

Gupta P, Rettiganti M, Fisher PL, Chang AC, Rice TB, Wetzel RC.

Crit Care Med. 2016 Dec;44(12):2131-2138.

PMID:
27513535
31.

Comparison of modern locked plating and antiglide plating for fixation of osteoporotic distal fibular fractures.

Switaj PJ, Wetzel RJ, Jain NP, Weatherford BM, Ren Y, Zhang LQ, Merk BR.

Foot Ankle Surg. 2016 Sep;22(3):158-163. doi: 10.1016/j.fas.2015.06.007. Epub 2015 Jul 4.

PMID:
27502223
32.

Hemorrhagic lumbar synovial facet cyst secondary to transforaminal epidural injection: A case report and review of the literature.

Elgafy H, Peters N, Lea JE, Wetzel RM.

World J Orthop. 2016 Jul 18;7(7):452-7. doi: 10.5312/wjo.v7.i7.452. eCollection 2016 Jul 18.

33.

Impact of 24/7 In-Hospital Intensivist Coverage on Outcomes in Pediatric Intensive Care. A Multicenter Study.

Gupta P, Rettiganti M, Rice TB, Wetzel RC.

Am J Respir Crit Care Med. 2016 Dec 15;194(12):1506-1513.

PMID:
27367580
34.

Folding Landscape of Mutant Huntingtin Exon1: Diffusible Multimers, Oligomers and Fibrils, and No Detectable Monomer.

Sahoo B, Arduini I, Drombosky KW, Kodali R, Sanders LH, Greenamyre JT, Wetzel R.

PLoS One. 2016 Jun 6;11(6):e0155747. doi: 10.1371/journal.pone.0155747. eCollection 2016.

35.

Risk factors and outcomes of in-hospital cardiac arrest following pediatric heart operations of varying complexity.

Gupta P, Rettiganti M, Jeffries HE, Scanlon MC, Ghanayem NS, Daufeldt J, Rice TB, Wetzel RC.

Resuscitation. 2016 Aug;105:1-7. doi: 10.1016/j.resuscitation.2016.04.022. Epub 2016 May 13.

PMID:
27185218
36.

Effect of Inhaled Nitric Oxide on Outcomes in Children With Acute Lung Injury: Propensity Matched Analysis From a Linked Database.

Gupta P, Richardson T, Hall M, Bertoch D, Hebbar KB, Fortenberry JD, Wetzel RC.

Crit Care Med. 2016 Oct;44(10):1901-9. doi: 10.1097/CCM.0000000000001837.

PMID:
27163193
37.

Pediatric Triage in a Severe Pandemic: Maximizing Survival by Establishing Triage Thresholds.

Gall C, Wetzel R, Kolker A, Kanter RK, Toltzis P.

Crit Care Med. 2016 Sep;44(9):1762-8. doi: 10.1097/CCM.0000000000001759.

PMID:
27071069
38.

Obesity and Mortality Risk in Critically Ill Children.

Ross PA, Newth CJ, Leung D, Wetzel RC, Khemani RG.

Pediatrics. 2016 Mar;137(3):e20152035. doi: 10.1542/peds.2015-2035. Epub 2016 Feb 16.

39.

Huntingtin exon 1 fibrils feature an interdigitated β-hairpin-based polyglutamine core.

Hoop CL, Lin HK, Kar K, Magyarfalvi G, Lamley JM, Boatz JC, Mandal A, Lewandowski JR, Wetzel R, van der Wel PC.

Proc Natl Acad Sci U S A. 2016 Feb 9;113(6):1546-51. doi: 10.1073/pnas.1521933113. Epub 2016 Feb 1.

40.

Sacral erosion and insufficiency fracture secondary to dural ectasia in patient with Marfan syndrome.

Elgafy H, Peters N, Wetzel RM.

Spine J. 2016 May;16(5):e301-2. doi: 10.1016/j.spinee.2015.11.007. Epub 2015 Nov 17. No abstract available.

PMID:
26598134
41.

Risk factors for mechanical ventilation and reintubation after pediatric heart surgery.

Gupta P, Rettiganti M, Gossett JM, Yeh JC, Jeffries HE, Rice TB, Wetzel RC.

J Thorac Cardiovasc Surg. 2016 Feb;151(2):451-8.e3. doi: 10.1016/j.jtcvs.2015.09.080. Epub 2015 Sep 28.

42.

Fluorescence Correlation Spectroscopy: A Tool to Study Protein Oligomerization and Aggregation In Vitro and In Vivo.

Sahoo B, Drombosky KW, Wetzel R.

Methods Mol Biol. 2016;1345:67-87. doi: 10.1007/978-1-4939-2978-8_5.

PMID:
26453206
43.

Association of house staff training with mortality in children with critical illness.

Gupta P, Tang X, Rettiganti M, Lauer C, Kacmarek RM, Rice TB, Markovitz BP, Wetzel RC.

Acta Paediatr. 2016 Feb;105(2):e60-6. doi: 10.1111/apa.13223. Epub 2015 Nov 13.

PMID:
26399703
44.

Pediatric Index of Cardiac Surgical Intensive Care Mortality Risk Score for Pediatric Cardiac Critical Care.

Jeffries HE, Soto-Campos G, Katch A, Gall C, Rice TB, Wetzel R.

Pediatr Crit Care Med. 2015 Nov;16(9):846-52. doi: 10.1097/PCC.0000000000000489.

PMID:
26196254
45.

C-Terminal Threonine Reduces Aβ43 Amyloidogenicity Compared with Aβ42.

Chemuru S, Kodali R, Wetzel R.

J Mol Biol. 2016 Jan 29;428(2 Pt A):274-291. doi: 10.1016/j.jmb.2015.06.008. Epub 2015 Jun 26.

46.

Evidence-Based Pediatric Outcome Predictors to Guide the Allocation of Critical Care Resources in a Mass Casualty Event.

Toltzis P, Soto-Campos G, Shelton C, Kuhn EM, Hahn R, Kanter RK, Wetzel RC.

Pediatr Crit Care Med. 2015 Sep;16(7):e207-16. doi: 10.1097/PCC.0000000000000481. Erratum in: Pediatr Crit Care Med. 2016 Jan;17(1):e28. Shelton, Christian R [added].

PMID:
26121100
47.

Critical care for rare diseases (and procedures): redux.

Fackler J, Lehmann HP, Wetzel RC.

Pediatr Crit Care Med. 2015 Mar;16(3):297-9. doi: 10.1097/PCC.0000000000000360. No abstract available.

PMID:
25738931
48.

Variation of ventilation practices with center volume after pediatric heart surgery.

Gupta P, Tang X, Gossett JM, Gall CM, Lauer C, Rice TB, Wetzel RC.

Clin Cardiol. 2015 Mar;38(3):178-84. doi: 10.1002/clc.22374. Epub 2015 Feb 23.

49.

Transcript co-variance with Nestin in two mouse genetic reference populations identifies Lef1 as a novel candidate regulator of neural precursor cell proliferation in the adult hippocampus.

Ashbrook DG, Delprato A, Grellmann C, Klein M, Wetzel R, Overall RW, Badea A.

Front Neurosci. 2014 Dec 12;8:418. doi: 10.3389/fnins.2014.00418. eCollection 2014.

50.

Adequate Vitamin D3 Supplementation During Pregnancy: Decreasing the Prevalence of Asthma and Food Allergies.

Finkel J, Cira C, Mazzella L, Bartyzel J, Ramanna A, Strimel K, Waturuocha A, Musser N, Burress J, Brammer S, Wetzel R, Horzempa J.

Matern Pediatr Nutr. 2015;2(1). pii: 105. Epub 2015 Dec 28.

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