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Items: 1 to 50 of 107

1.

A Biparatopic HER2-Targeting Antibody-Drug Conjugate Induces Tumor Regression in Primary Models Refractory to or Ineligible for HER2-Targeted Therapy.

Li JY, Perry SR, Muniz-Medina V, Wang X, Wetzel LK, Rebelatto MC, Masson Hinrichs MJ, Bezabeh BZ, Fleming RL, Dimasi N, Feng H, Toader D, Yuan AQ, Xu L, Lin J, Gao C, Wu H, Dixit R, Osbourn JK, Coats SR.

Cancer Cell. 2019 Jun 10;35(6):948-949. doi: 10.1016/j.ccell.2019.05.010. No abstract available.

PMID:
31185215
2.

TgCentrin2 is required for invasion and replication in the human parasite Toxoplasma gondii.

Leung JM, Liu J, Wetzel LA, Hu K.

J Cell Sci. 2019 Jun 10. pii: jcs.228791. doi: 10.1242/jcs.228791. [Epub ahead of print]

PMID:
31182647
3.

Predicted glycosyltransferases promote development and prevent spurious cell clumping in the choanoflagellate S. rosetta.

Wetzel LA, Levin TC, Hulett RE, Chan D, King GA, Aldayafleh R, Booth DS, Sigg MA, King N.

Elife. 2018 Dec 17;7. pii: e41482. doi: 10.7554/eLife.41482.

4.

Evaluation of Pyrrolobenzodiazepine-Loaded Nanoparticles: A Targeted Drug Delivery Approach.

Tyagi P, Pechenov S, RiosDoria J, Masterson L, Dickinson NJ, Howard P, Mao S, Harper J, Wetzel L, Yo K, Subramony JA.

J Pharm Sci. 2019 Apr;108(4):1590-1597. doi: 10.1016/j.xphs.2018.11.023. Epub 2018 Nov 22.

PMID:
30472264
5.

Preclinical assessment of an antibody-PBD conjugate that targets BCMA on multiple myeloma and myeloma progenitor cells.

Kinneer K, Flynn M, Thomas SB, Meekin J, Varkey R, Xiao X, Zhong H, Breen S, Hynes PG, Fleming R, Bezabeh B, Chen CT, Wetzel L, Chen R, Dimasi N, Tai YT, Anderson KC, Herbst R, Howard PW, Hurt EM, Tice DA.

Leukemia. 2019 Mar;33(3):766-771. doi: 10.1038/s41375-018-0278-7. Epub 2018 Oct 12. No abstract available.

PMID:
30315237
6.

Juvenile coho salmon growth and health in streams across an urbanization gradient.

Spanjer AR, Moran PW, Larsen KA, Wetzel LA, Hansen AG, Beauchamp DA.

Sci Total Environ. 2018 Jun 1;625:1003-1012. doi: 10.1016/j.scitotenv.2017.12.327. Epub 2018 Jan 5.

PMID:
29996397
7.

Preclinical Evaluation of MEDI0641, a Pyrrolobenzodiazepine-Conjugated Antibody-Drug Conjugate Targeting 5T4.

Harper J, Lloyd C, Dimasi N, Toader D, Marwood R, Lewis L, Bannister D, Jovanovic J, Fleming R, D'Hooge F, Mao S, Marrero AM, Korade M 3rd, Strout P, Xu L, Chen C, Wetzel L, Breen S, van Vlerken-Ysla L, Jalla S, Rebelatto M, Zhong H, Hurt EM, Hinrichs MJ, Huang K, Howard PW, Tice DA, Hollingsworth RE, Herbst R, Kamal A.

Mol Cancer Ther. 2017 Aug;16(8):1576-1587. doi: 10.1158/1535-7163.MCT-16-0825. Epub 2017 May 18.

8.
9.

Antibody-Drug Conjugates Bearing Pyrrolobenzodiazepine or Tubulysin Payloads Are Immunomodulatory and Synergize with Multiple Immunotherapies.

Rios-Doria J, Harper J, Rothstein R, Wetzel L, Chesebrough J, Marrero A, Chen C, Strout P, Mulgrew K, McGlinchey K, Fleming R, Bezabeh B, Meekin J, Stewart D, Kennedy M, Martin P, Buchanan A, Dimasi N, Michelotti E, Hollingsworth R.

Cancer Res. 2017 May 15;77(10):2686-2698. doi: 10.1158/0008-5472.CAN-16-2854. Epub 2017 Mar 10.

10.

Self-organized synchronization of digital phase-locked loops with delayed coupling in theory and experiment.

Wetzel L, Jörg DJ, Pollakis A, Rave W, Fettweis G, Jülicher F.

PLoS One. 2017 Feb 16;12(2):e0171590. doi: 10.1371/journal.pone.0171590. eCollection 2017.

11.

Isolation of luteal endothelial cells and functional interactions with T lymphocytes.

Walusimbi SS, Wetzel LM, Townson DH, Pate JL.

Reproduction. 2017 May;153(5):519-533. doi: 10.1530/REP-16-0578. Epub 2017 Feb 7.

PMID:
28174320
12.

Disseminated cat-scratch disease in an adult with selective IgA deficiency.

Rohr A, Ash R, Vadaparampil J, Hill J, Wetzel L.

Radiol Case Rep. 2016 Apr 8;11(2):54-7. doi: 10.1016/j.radcr.2016.02.016. eCollection 2016 Jun.

13.

Lipid- and polyion complex-based micelles as agonist platforms for TNFR superfamily receptors.

Gilbreth RN, Novarra S, Wetzel L, Florinas S, Cabral H, Kataoka K, Rios-Doria J, Christie RJ, Baca M.

J Control Release. 2016 Jul 28;234:104-14. doi: 10.1016/j.jconrel.2016.05.041. Epub 2016 May 17.

PMID:
27212104
14.

A Potent HER3 Monoclonal Antibody That Blocks Both Ligand-Dependent and -Independent Activities: Differential Impacts of PTEN Status on Tumor Response.

Xiao Z, Carrasco RA, Schifferli K, Kinneer K, Tammali R, Chen H, Rothstein R, Wetzel L, Yang C, Chowdhury P, Tsui P, Steiner P, Jallal B, Herbst R, Hollingsworth RE, Tice DA.

Mol Cancer Ther. 2016 Apr;15(4):689-701. doi: 10.1158/1535-7163.MCT-15-0555. Epub 2016 Feb 15.

15.

A Biparatopic HER2-Targeting Antibody-Drug Conjugate Induces Tumor Regression in Primary Models Refractory to or Ineligible for HER2-Targeted Therapy.

Li JY, Perry SR, Muniz-Medina V, Wang X, Wetzel LK, Rebelatto MC, Hinrichs MJ, Bezabeh BZ, Fleming RL, Dimasi N, Feng H, Toader D, Yuan AQ, Xu L, Lin J, Gao C, Wu H, Dixit R, Osbourn JK, Coats SR.

Cancer Cell. 2016 Jan 11;29(1):117-29. doi: 10.1016/j.ccell.2015.12.008. Erratum in: Cancer Cell. 2019 Jun 10;35(6):948-949.

16.

Doxil synergizes with cancer immunotherapies to enhance antitumor responses in syngeneic mouse models.

Rios-Doria J, Durham N, Wetzel L, Rothstein R, Chesebrough J, Holoweckyj N, Zhao W, Leow CC, Hollingsworth R.

Neoplasia. 2015 Aug;17(8):661-70. doi: 10.1016/j.neo.2015.08.004.

17.

Comparison of patient intake of ticagrelor, prasugrel, or clopidogrel on restoring platelet function by donor platelets.

Scharbert G, Wetzel L, Schrottmaier WC, Kral JB, Weber T, Assinger A.

Transfusion. 2015 Jun;55(6):1320-6. doi: 10.1111/trf.12977. Epub 2015 Jan 15.

PMID:
25641006
18.

In reply to Whitley et al.

Kirchheiner K, Czajka-Pepl A, Ponocny-Seliger E, Scharbert G, Wetzel L, Nout RA, Sturdza A, Dimopoulos JC, Dörr W, Pötter R.

Int J Radiat Oncol Biol Phys. 2014 Oct 1;90(2):469-70. doi: 10.1016/j.ijrobp.2014.06.051. No abstract available.

PMID:
25304801
19.

The Rosetteless gene controls development in the choanoflagellate S. rosetta.

Levin TC, Greaney AJ, Wetzel L, King N.

Elife. 2014 Oct 9;3. doi: 10.7554/eLife.04070.

20.

Inflammatory Myofibroblastic Tumor: A Case Study.

Powell CL, Holzbeierlein JM, Wetzel L, Padmanabhan P.

Urol Case Rep. 2014 Jun 25;2(5):173-5. doi: 10.1016/j.eucr.2014.05.010. eCollection 2014 Sep.

21.

Posttraumatic stress disorder after high-dose-rate brachytherapy for cervical cancer with 2 fractions in 1 application under spinal/epidural anesthesia: incidence and risk factors.

Kirchheiner K, Czajka-Pepl A, Ponocny-Seliger E, Scharbert G, Wetzel L, Nout RA, Sturdza A, Dimopoulos JC, Dörr W, Pötter R.

Int J Radiat Oncol Biol Phys. 2014 Jun 1;89(2):260-7. doi: 10.1016/j.ijrobp.2014.02.018. Epub 2014 Apr 7.

PMID:
24721589
22.

Anterior Spinal Surgery Involving Variant Vascular Anatomy: A Case Report.

Amin TJ, Burton DC, Delcore R, Wetzel LH.

Spine Deform. 2013 Nov;1(6):468-472. doi: 10.1016/j.jspd.2013.08.001. Epub 2013 Nov 21.

PMID:
27927375
23.

Intravenous nonopioid analgesic drugs in chronic low back pain patients on chronic opioid treatment: a crossover, randomised, double-blinded, placebo-controlled study.

Wetzel L, Zadrazil M, Paternostro-Sluga T, Authried G, Kozek-Langenecker S, Scharbert G.

Eur J Anaesthesiol. 2014 Jan;31(1):35-40. doi: 10.1097/EJA.0b013e328365ae28. Retraction in: Eur J Anaesthesiol. 2015 Apr;32(4):287.

PMID:
24141646
24.

Novel thioredoxin-like proteins are components of a protein complex coating the cortical microtubules of Toxoplasma gondii.

Liu J, Wetzel L, Zhang Y, Nagayasu E, Ems-McClung S, Florens L, Hu K.

Eukaryot Cell. 2013 Dec;12(12):1588-99. doi: 10.1128/EC.00082-13. Epub 2013 Jul 19.

25.

Effect of the carrier solution for hydroxyethyl starch on platelet aggregation and clot formation.

Schaden E, Wetzel L, Kozek-Langenecker S, Thaler U, Scharbert G.

Br J Anaesth. 2012 Oct;109(4):572-7. doi: 10.1093/bja/aes229. Epub 2012 Jul 11.

26.

Detected renal cysts are tips of the iceberg in adults with ADPKD.

Grantham JJ, Mulamalla S, Grantham CJ, Wallace DP, Cook LT, Wetzel LH, Fields TA, Bae KT.

Clin J Am Soc Nephrol. 2012 Jul;7(7):1087-93. doi: 10.2215/CJN.00900112. Epub 2012 May 10.

27.

Heparin-induced effects of prothrombin complex concentrates in thromboelastometry.

Scharbert G, Thaler U, Weilnböck C, Wetzel L, Kozek-Langenecker S.

Wien Klin Wochenschr. 2012 May;124(9-10):320-5. doi: 10.1007/s00508-012-0171-8. Epub 2012 May 11.

PMID:
22576961
28.

Less blood loss with tetrastarch.

Wetzel L, Kozek-Langenecker S.

Intensive Care Med. 2012 Jun;38(6):1078-9; author reply1080-1. doi: 10.1007/s00134-012-2552-x. Epub 2012 Apr 11. No abstract available.

PMID:
22491940
29.

Kidney volume and functional outcomes in autosomal dominant polycystic kidney disease.

Chapman AB, Bost JE, Torres VE, Guay-Woodford L, Bae KT, Landsittel D, Li J, King BF, Martin D, Wetzel LH, Lockhart ME, Harris PC, Moxey-Mims M, Flessner M, Bennett WM, Grantham JJ.

Clin J Am Soc Nephrol. 2012 Mar;7(3):479-86. doi: 10.2215/CJN.09500911. Epub 2012 Feb 16.

30.

Analysis of baseline parameters in the HALT polycystic kidney disease trials.

Torres VE, Chapman AB, Perrone RD, Bae KT, Abebe KZ, Bost JE, Miskulin DC, Steinman TI, Braun WE, Winklhofer FT, Hogan MC, Oskoui FR, Kelleher C, Masoumi A, Glockner J, Halin NJ, Martin DR, Remer E, Patel N, Pedrosa I, Wetzel LH, Thompson PA, Miller JP, Meyers CM, Schrier RW; HALT PKD Study Group.

Kidney Int. 2012 Mar;81(6):577-85. doi: 10.1038/ki.2011.411. Epub 2011 Dec 28.

31.

Allergic reaction after dextran.

Wetzel L, Kozek-Langenecker S.

Acta Anaesthesiol Scand. 2012 Jan;56(1):132; author reply 132-3. doi: 10.1111/j.1399-6576.2011.02515.x. Epub 2011 Sep 7. No abstract available.

PMID:
22092241
32.

Cardiac magnetic resonance assessment of left ventricular mass in autosomal dominant polycystic kidney disease.

Perrone RD, Abebe KZ, Schrier RW, Chapman AB, Torres VE, Bost J, Kaya D, Miskulin DC, Steinman TI, Braun W, Winklhofer FT, Hogan MC, Rahbari-Oskoui F, Kelleher C, Masoumi A, Glockner J, Halin NJ, Martin D, Remer E, Patel N, Pedrosa I, Wetzel LH, Thompson PA, Miller JP, Bae KT; HALT PKD Study Group, Meyers CM.

Clin J Am Soc Nephrol. 2011 Oct;6(10):2508-15. doi: 10.2215/CJN.04610511. Epub 2011 Sep 8.

33.

Communication with survivors of motor vehicle crashes.

Marco CA, Wetzel LR.

Emerg Med J. 2012 Aug;29(8):626-9. doi: 10.1136/emermed-2011-200059. Epub 2011 Aug 19.

PMID:
21856704
34.

Circumaortic renal vein tumor thrombus in renal cell carcinoma.

Lee EK, Wetzel LH, Holzbeierlein JM.

Int J Urol. 2011 Aug;18(8):605-6. doi: 10.1111/j.1442-2042.2011.02790.x. Epub 2011 Jun 9. No abstract available.

35.

Quality of colonoscopy withdrawal technique and variability in adenoma detection rates (with videos).

Lee RH, Tang RS, Muthusamy VR, Ho SB, Shah NK, Wetzel L, Bain AS, Mackintosh EE, Paek AM, Crissien AM, Saraf LJ, Kalmaz DM, Savides TJ.

Gastrointest Endosc. 2011 Jul;74(1):128-34. doi: 10.1016/j.gie.2011.03.003. Epub 2011 Apr 30.

PMID:
21531410
36.

Potentially modifiable factors affecting the progression of autosomal dominant polycystic kidney disease.

Torres VE, Grantham JJ, Chapman AB, Mrug M, Bae KT, King BF Jr, Wetzel LH, Martin D, Lockhart ME, Bennett WM, Moxey-Mims M, Abebe KZ, Lin Y, Bost JE; Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease (CRISP).

Clin J Am Soc Nephrol. 2011 Mar;6(3):640-7. doi: 10.2215/CJN.03250410. Epub 2010 Nov 18.

37.

Use of brain MRI after deep brain stimulation hardware implantation.

Nazzaro JM, Lyons KE, Wetzel LH, Pahwa R.

Int J Neurosci. 2010 Mar;120(3):176-83. doi: 10.3109/00207450903389156.

PMID:
20374084
38.

Evidence of extraordinary growth in the progressive enlargement of renal cysts.

Grantham JJ, Cook LT, Wetzel LH, Cadnapaphornchai MA, Bae KT.

Clin J Am Soc Nephrol. 2010 May;5(5):889-96. doi: 10.2215/CJN.00550110. Epub 2010 Apr 1.

39.

Imminent cardiac risk assessment via optical intravascular biochemical analysis.

Wetzel DL, Wetzel LH, Wetzel MD, Lodder RA.

Analyst. 2009 Jun;134(6):1099-106. doi: 10.1039/b821164g. Epub 2009 Apr 9.

PMID:
19475135
40.

MCAK and paclitaxel have differential effects on spindle microtubule organization and dynamics.

Rizk RS, Bohannon KP, Wetzel LA, Powers J, Shaw SL, Walczak CE.

Mol Biol Cell. 2009 Mar;20(6):1639-51. doi: 10.1091/mbc.E08-09-0985. Epub 2009 Jan 21.

41.
42.

Transesophageal Echocardiographyfor Detection Of Left Atrial Appendage Thrombi: Is It Good Enough?

Biria A, Rosamond T, Lakkireddy D, Wetzel L.

J Atr Fibrillation. 2008 May 16;1(1):10. doi: 10.4022/jafib.10. eCollection 2008 May-Jun. No abstract available.

43.

IntraCameral right coronary artery: detection by 64 slice coronary computed tomographic angiography and implications for radiofrequency ablation of atrial dysrhythmias.

Rosamond T, Wetzel LH, Lakkireddy D, Ferrell R, Tadros P.

Pacing Clin Electrophysiol. 2007 Dec;30(12):1571-4.

PMID:
18070317
44.

Magnetic resonance imaging evaluation of hepatic cysts in early autosomal-dominant polycystic kidney disease: the Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease cohort.

Bae KT, Zhu F, Chapman AB, Torres VE, Grantham JJ, Guay-Woodford LM, Baumgarten DA, King BF Jr, Wetzel LH, Kenney PJ, Brummer ME, Bennett WM, Klahr S, Meyers CM, Zhang X, Thompson PA, Miller JP; Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease (CRISP).

Clin J Am Soc Nephrol. 2006 Jan;1(1):64-9. Epub 2005 Oct 26.

45.

Development and assessment of a neuropsychological battery to aid in predicting driving performance.

Szlyk JP, Myers L, Zhang Y, Wetzel L, Shapiro R.

J Rehabil Res Dev. 2002 Jul-Aug;39(4):483-96.

46.

Cyst number but not the rate of cystic growth is associated with the mutated gene in autosomal dominant polycystic kidney disease.

Harris PC, Bae KT, Rossetti S, Torres VE, Grantham JJ, Chapman AB, Guay-Woodford LM, King BF, Wetzel LH, Baumgarten DA, Kenney PJ, Consugar M, Klahr S, Bennett WM, Meyers CM, Zhang QJ, Thompson PA, Zhu F, Miller JP.

J Am Soc Nephrol. 2006 Nov;17(11):3013-9. Epub 2006 Oct 11.

47.

Assessment of microscopic hematuria in adults.

McDonald MM, Swagerty D, Wetzel L.

Am Fam Physician. 2006 May 15;73(10):1748-54.

48.

Initial evaluation of a computer-based medication management tool in a geriatric clinic.

Hornick TR, Higgins PA, Stollings C, Wetzel L, Barzilai K, Wolpaw D.

Am J Geriatr Pharmacother. 2006 Mar;4(1):62-9.

PMID:
16730622
49.

Volume progression in polycystic kidney disease.

Grantham JJ, Torres VE, Chapman AB, Guay-Woodford LM, Bae KT, King BF Jr, Wetzel LH, Baumgarten DA, Kenney PJ, Harris PC, Klahr S, Bennett WM, Hirschman GN, Meyers CM, Zhang X, Zhu F, Miller JP; CRISP Investigators.

N Engl J Med. 2006 May 18;354(20):2122-30.

50.

Sonographic assessment of the severity and progression of autosomal dominant polycystic kidney disease: the Consortium of Renal Imaging Studies in Polycystic Kidney Disease (CRISP).

O'Neill WC, Robbin ML, Bae KT, Grantham JJ, Chapman AB, Guay-Woodford LM, Torres VE, King BF, Wetzel LH, Thompson PA, Miller JP.

Am J Kidney Dis. 2005 Dec;46(6):1058-64.

PMID:
16310571

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