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Items: 34


Engineering Recombinant Reoviruses To Display gp41 Membrane-Proximal External-Region Epitopes from HIV-1.

Boehme KW, Ikizler M, Iskarpatyoti JA, Wetzel JD, Willis J, Crowe JE Jr, LaBranche CC, Montefiori DC, Wilson GJ, Dermody TS.

mSphere. 2016 May 18;1(3). pii: e00086-16. doi: 10.1128/mSphere.00086-16. eCollection 2016 May-Jun.


Increased congregational support for parents of children with cystic fibrosis.

Szczesniak RD, Zou Y, Wetzel JD, Krause N, Grossoehme DH.

J Relig Health. 2015 Apr;54(2):664-75. doi: 10.1007/s10943-014-9928-x.


The impact of transforming healthcare delivery on cystic fibrosis outcomes: a decade of quality improvement at Cincinnati Children's Hospital.

Siracusa CM, Weiland JL, Acton JD, Chima AK, Chini BA, Hoberman AJ, Wetzel JD, Amin RS, McPhail GL.

BMJ Qual Saf. 2014 Apr;23 Suppl 1:i56-i63. doi: 10.1136/bmjqs-2013-002361.


Nebulized liposomal amikacin for the treatment of Pseudomonas aeruginosa infection in cystic fibrosis patients.

Ehsan Z, Wetzel JD, Clancy JP.

Expert Opin Investig Drugs. 2014 May;23(5):743-9. doi: 10.1517/13543784.2014.895322. Epub 2014 Mar 5. Review.


Mutations in the rotavirus spike protein VP4 reduce trypsin sensitivity but not viral spread.

Trask SD, Wetzel JD, Dermody TS, Patton JT.

J Gen Virol. 2013 Jun;94(Pt 6):1296-300. doi: 10.1099/vir.0.050674-0. Epub 2013 Feb 20.


Serotype-specific differences in inhibition of reovirus infectivity by human-milk glycans are determined by viral attachment protein σ1.

Iskarpatyoti JA, Morse EA, McClung RP, Ikizler M, Wetzel JD, Contractor N, Dermody TS.

Virology. 2012 Nov 25;433(2):489-97. doi: 10.1016/j.virol.2012.08.036. Epub 2012 Sep 19.


A rapid, automated approach for quantitation of rotavirus and reovirus infectivity.

Iskarpatyoti JA, Willis JZ, Guan J, Morse EA, Ikizler M, Wetzel JD, Dermody TS, Contractor N.

J Virol Methods. 2012 Sep;184(1-2):1-7. doi: 10.1016/j.jviromet.2012.03.018. Epub 2012 Mar 23.


Molecular determinants of proteolytic disassembly of the reovirus outer capsid.

Doyle JD, Danthi P, Kendall EA, Ooms LS, Wetzel JD, Dermody TS.

J Biol Chem. 2012 Mar 9;287(11):8029-38. doi: 10.1074/jbc.M111.334854. Epub 2012 Jan 17.


Genetic and pharmacologic alteration of cathepsin expression influences reovirus pathogenesis.

Johnson EM, Doyle JD, Wetzel JD, McClung RP, Katunuma N, Chappell JD, Washington MK, Dermody TS.

J Virol. 2009 Oct;83(19):9630-40. doi: 10.1128/JVI.01095-09. Epub 2009 Jul 29.


Reovirus preferentially infects the basolateral surface and is released from the apical surface of polarized human respiratory epithelial cells.

Excoffon KJ, Guglielmi KM, Wetzel JD, Gansemer ND, Campbell JA, Dermody TS, Zabner J.

J Infect Dis. 2008 Apr 15;197(8):1189-97. doi: 10.1086/529515.


A plasmid-based reverse genetics system for animal double-stranded RNA viruses.

Kobayashi T, Antar AA, Boehme KW, Danthi P, Eby EA, Guglielmi KM, Holm GH, Johnson EM, Maginnis MS, Naik S, Skelton WB, Wetzel JD, Wilson GJ, Chappell JD, Dermody TS.

Cell Host Microbe. 2007 Apr 19;1(2):147-57. Erratum in: Cell Host Microbe. 2007 Aug 16;2(2):139.


Type I interferons produced by hematopoietic cells protect mice against lethal infection by mammalian reovirus.

Johansson C, Wetzel JD, He J, Mikacenic C, Dermody TS, Kelsall BL.

J Exp Med. 2007 Jun 11;204(6):1349-58. Epub 2007 May 14.


Autonomous reovirus strain classification using filament-coupled antibodies.

Stone GP, Wetzel JD, Russ PK, Dermody TS, Haselton FR.

Ann Biomed Eng. 2006 Nov;34(11):1778-85. Epub 2006 Oct 10.


Reovirus strain-dependent inflammatory cytokine responses and replication patterns in a human monocyte cell line.

Farone AL, O'Donnell SM, Brooks CS, Young KM, Pierce JM, Wetzel JD, Dermody TS, Farone MB.

Viral Immunol. 2006 Summer;19(3):546-57.


Reovirus delays diabetes onset but does not prevent insulitis in nonobese diabetic mice.

Wetzel JD, Barton ES, Chappell JD, Baer GS, Mochow-Grundy M, Rodgers SE, Shyr Y, Powers AC, Thomas JW, Dermody TS.

J Virol. 2006 Mar;80(6):3078-82.


Reovirus variants selected for resistance to ammonium chloride have mutations in viral outer-capsid protein sigma3.

Clark KM, Wetzel JD, Gu Y, Ebert DH, McAbee SA, Stoneman EK, Baer GS, Zhu Y, Wilson GJ, Prasad BV, Dermody TS.

J Virol. 2006 Jan;80(2):671-81.


Organ-specific roles for transcription factor NF-kappaB in reovirus-induced apoptosis and disease.

O'Donnell SM, Hansberger MW, Connolly JL, Chappell JD, Watson MJ, Pierce JM, Wetzel JD, Han W, Barton ES, Forrest JC, Valyi-Nagy T, Yull FE, Blackwell TS, Rottman JN, Sherry B, Dermody TS.

J Clin Invest. 2005 Sep;115(9):2341-50. Epub 2005 Aug 11.


Junctional adhesion molecule a serves as a receptor for prototype and field-isolate strains of mammalian reovirus.

Campbell JA, Schelling P, Wetzel JD, Johnson EM, Forrest JC, Wilson GA, Aurrand-Lions M, Imhof BA, Stehle T, Dermody TS.

J Virol. 2005 Jul;79(13):7967-78.


Peyer's patch dendritic cells process viral antigen from apoptotic epithelial cells in the intestine of reovirus-infected mice.

Fleeton MN, Contractor N, Leon F, Wetzel JD, Dermody TS, Kelsall BL.

J Exp Med. 2004 Jul 19;200(2):235-45.


Isolation and molecular characterization of a novel type 3 reovirus from a child with meningitis.

Tyler KL, Barton ES, Ibach ML, Robinson C, Campbell JA, O'Donnell SM, Valyi-Nagy T, Clarke P, Wetzel JD, Dermody TS.

J Infect Dis. 2004 May 1;189(9):1664-75. Epub 2004 Apr 15.


Utilization of sialic acid as a coreceptor is required for reovirus-induced biliary disease.

Barton ES, Youree BE, Ebert DH, Forrest JC, Connolly JL, Valyi-Nagy T, Washington K, Wetzel JD, Dermody TS.

J Clin Invest. 2003 Jun;111(12):1823-33.


Detection of reovirus by reverse transcription-polymerase chain reaction using primers corresponding to conserved regions of the viral L1 genome segment.

Leary TP, Erker JC, Chalmers ML, Wetzel JD, Desai SM, Mushahwar IK, Dermody TS.

J Virol Methods. 2002 Jul;104(2):161-5.


Detection of mammalian reovirus RNA by using reverse transcription-PCR: sequence diversity within the lambda3-encoding L1 gene.

Leary TP, Erker JC, Chalmers ML, Cruz AT, Wetzel JD, Desai SM, Mushahwar IK, Dermody TS.

J Clin Microbiol. 2002 Apr;40(4):1368-75.


A monoclonal antibody specific for reovirus outer-capsid protein sigma3 inhibits sigma1-mediated hemagglutination by steric hindrance.

Nason EL, Wetzel JD, Mukherjee SK, Barton ES, Prasad BV, Dermody TS.

J Virol. 2001 Jul;75(14):6625-34.


Viruses and cells with mutations affecting viral entry are selected during persistent rotavirus infections of MA104 cells.

Mrukowicz JZ, Wetzel JD, Goral MI, Fogo AB, Wright PF, Dermody TS.

J Virol. 1998 Apr;72(4):3088-97.


Persistent reovirus infections of L cells select mutations in viral attachment protein sigma1 that alter oligomer stability.

Wilson GJ, Wetzel JD, Puryear W, Bassel-Duby R, Dermody TS.

J Virol. 1996 Oct;70(10):6598-606.


Binding of type 3 reovirus by a domain of the sigma 1 protein important for hemagglutination leads to infection of murine erythroleukemia cells.

Rubin DH, Wetzel JD, Williams WV, Cohen JA, Dworkin C, Dermody TS.

J Clin Invest. 1992 Dec;90(6):2536-42.

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