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Items: 1 to 50 of 64

1.

Expression of AXL receptor tyrosine kinase relates to monocyte dysfunction and severity of cirrhosis.

Brenig R, Pop OT, Triantafyllou E, Geng A, Singanayagam A, Perez-Shibayama C, Besse L, Cupovic J, Künzler P, Boldanova T, Brand S, Semela D, Duong FH, Weston CJ, Ludewig B, Heim MH, Wendon J, Antoniades CG, Bernsmeier C.

Life Sci Alliance. 2019 Dec 10;3(1). pii: e201900465. doi: 10.26508/lsa.201900465. Print 2020 Jan.

2.

Resolving the fibrotic niche of human liver cirrhosis at single-cell level.

Ramachandran P, Dobie R, Wilson-Kanamori JR, Dora EF, Henderson BEP, Luu NT, Portman JR, Matchett KP, Brice M, Marwick JA, Taylor RS, Efremova M, Vento-Tormo R, Carragher NO, Kendall TJ, Fallowfield JA, Harrison EM, Mole DJ, Wigmore SJ, Newsome PN, Weston CJ, Iredale JP, Tacke F, Pollard JW, Ponting CP, Marioni JC, Teichmann SA, Henderson NC.

Nature. 2019 Nov;575(7783):512-518. doi: 10.1038/s41586-019-1631-3. Epub 2019 Oct 9.

PMID:
31597160
3.

Effect of thinning and burning fuel reduction treatments on forest carbon and bushfire fuel hazard in Eucalyptus sieberi forests of South-Eastern Australia.

Volkova L, Weston CJ.

Sci Total Environ. 2019 Dec 1;694:133708. doi: 10.1016/j.scitotenv.2019.133708. Epub 2019 Aug 1.

PMID:
31398652
4.

Obesity in acute alcoholic hepatitis increases morbidity and mortality.

Parker R, Kim SJ, Im GY, Nahas J, Dhesi B, Vergis N, Sinha A, Ghezzi A, Rink MR, McCune A, Aithal GP, Newsome PN, Weston CJ, Holt A, Gao B.

EBioMedicine. 2019 Jul;45:511-518. doi: 10.1016/j.ebiom.2019.03.046. Epub 2019 Jul 3.

5.

The Role of Myeloid-Derived Cells in the Progression of Liver Disease.

Weston CJ, Zimmermann HW, Adams DH.

Front Immunol. 2019 Apr 24;10:893. doi: 10.3389/fimmu.2019.00893. eCollection 2019. Review.

6.

Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer.

Malehmir M, Pfister D, Gallage S, Szydlowska M, Inverso D, Kotsiliti E, Leone V, Peiseler M, Surewaard BGJ, Rath D, Ali A, Wolf MJ, Drescher H, Healy ME, Dauch D, Kroy D, Krenkel O, Kohlhepp M, Engleitner T, Olkus A, Sijmonsma T, Volz J, Deppermann C, Stegner D, Helbling P, Nombela-Arrieta C, Rafiei A, Hinterleitner M, Rall M, Baku F, Borst O, Wilson CL, Leslie J, O'Connor T, Weston CJ, Adams DH, Sheriff L, Teijeiro A, Prinz M, Bogeska R, Anstee N, Bongers MN, Notohamiprodjo M, Geisler T, Withers DJ, Ware J, Mann DA, Augustin HG, Vegiopoulos A, Milsom MD, Rose AJ, Lalor PF, Llovet JM, Pinyol R, Tacke F, Rad R, Matter M, Djouder N, Kubes P, Knolle PA, Unger K, Zender L, Nieswandt B, Gawaz M, Weber A, Heikenwalder M.

Nat Med. 2019 Apr;25(4):641-655. doi: 10.1038/s41591-019-0379-5. Epub 2019 Apr 1.

7.

Novel Targets in the Immune Microenvironment of the Hepatic Sinusoids for Treating Liver Diseases.

Patten DA, Shepherd EL, Weston CJ, Shetty S.

Semin Liver Dis. 2019 May;39(2):111-123. doi: 10.1055/s-0039-1678727. Epub 2019 Mar 25. Erratum in: Semin Liver Dis. 2019 May;39(2):e1.

PMID:
30912097
8.

Fire intensity effects on post-fire fuel recovery in Eucalyptus open forests of south-eastern Australia.

Volkova L, Weiss Aparicio AG, Weston CJ.

Sci Total Environ. 2019 Jun 20;670:328-336. doi: 10.1016/j.scitotenv.2019.03.226. Epub 2019 Mar 16.

PMID:
30904646
9.

Aboveground carbon of community-managed Chirpine (Pinus roxburghii Sarg.) forests of Nepal based on stand types and geographic aspects.

Pariyar S, Volkova L, Sharma RP, Sunam R, Weston CJ.

PeerJ. 2019 Mar 8;7:e6494. doi: 10.7717/peerj.6494. eCollection 2019.

10.

The Reactive Oxygen Species-Mitophagy Signaling Pathway Regulates Liver Endothelial Cell Survival During Ischemia/Reperfusion Injury.

Bhogal RH, Weston CJ, Velduis S, G D Leuvenink H, Reynolds GM, Davies S, Nyguet-Thin L, Alfaifi M, Shepard EL, Boteon Y, Wallace L, Oo YH, Adams DH, Mirza DF, Mergental H, Muirhead G, Stephenson BTF, Afford SC.

Liver Transpl. 2018 Oct;24(10):1437-1452. doi: 10.1002/lt.25313.

11.

A data - Model fusion methodology for mapping bushfire fuels for smoke emissions forecasting in forested landscapes of south-eastern Australia.

Volkova L, Meyer CPM, Haverd V, Weston CJ.

J Environ Manage. 2018 Sep 15;222:21-29. doi: 10.1016/j.jenvman.2018.05.060. Epub 2018 May 23.

PMID:
29800860
12.

Importance of disturbance history on net primary productivity in the world's most productive forests and implications for the global carbon cycle.

Volkova L, Roxburgh SH, Weston CJ, Benyon RG, Sullivan AL, Polglase PJ.

Glob Chang Biol. 2018 Sep;24(9):4293-4303. doi: 10.1111/gcb.14309. Epub 2018 May 30.

PMID:
29758588
13.

Inhibition of semicarbazide-sensitive amine oxidase reduces atherosclerosis in apolipoprotein E-deficient mice.

Wang SH, Yu TY, Tsai FC, Weston CJ, Lin MS, Hung CS, Kao HL, Li YI, Solé M, Unzeta M, Chen YL, Chuang LM, Li HY.

Transl Res. 2018 Jul;197:12-31. doi: 10.1016/j.trsl.2018.03.001. Epub 2018 Mar 27.

PMID:
29653075
14.

CC chemokine receptor 2 promotes recruitment of myeloid cells associated with insulin resistance in nonalcoholic fatty liver disease.

Parker R, Weston CJ, Miao Z, Corbett C, Armstrong MJ, Ertl L, Ebsworth K, Walters MJ, Baumart T, Newland D, McMahon J, Zhang P, Singh R, Campbell J, Newsome PN, Charo I, Schall TJ, Adams DH.

Am J Physiol Gastrointest Liver Physiol. 2018 Apr 1;314(4):G483-G493. doi: 10.1152/ajpgi.00213.2017. Epub 2018 Feb 8.

15.

SCARF-1 promotes adhesion of CD4+ T cells to human hepatic sinusoidal endothelium under conditions of shear stress.

Patten DA, Kamarajah SK, Rose JM, Tickle J, Shepherd EL, Adams DH, Weston CJ, Shetty S.

Sci Rep. 2017 Dec 14;7(1):17600. doi: 10.1038/s41598-017-17928-4.

16.

Geometric confinement is required for recovery and maintenance of chondrocyte phenotype in alginate.

Cooke ME, Pearson MJ, Moakes RJA, Weston CJ, Davis ET, Jones SW, Grover LM.

APL Bioeng. 2017 Oct 9;1(1):016104. doi: 10.1063/1.5006752. eCollection 2017 Dec.

17.

Impaired Transmigration of Myeloid-Derived Suppressor Cells across Human Sinusoidal Endothelium Is Associated with Decreased Expression of CD13.

Resheq YJ, Menzner AK, Bosch J, Tickle J, Li KK, Wilhelm A, Hepburn E, Murihead G, Ward ST, Curbishley SM, Zimmermann HW, Bruns T, Gilbert DF, Tripal P, Mackensen A, Adams DH, Weston CJ.

J Immunol. 2017 Sep 1;199(5):1672-1681. doi: 10.4049/jimmunol.1600466. Epub 2017 Jul 24.

18.

CD14+ CD15- HLA-DR- myeloid-derived suppressor cells impair antimicrobial responses in patients with acute-on-chronic liver failure.

Bernsmeier C, Triantafyllou E, Brenig R, Lebosse FJ, Singanayagam A, Patel VC, Pop OT, Khamri W, Nathwani R, Tidswell R, Weston CJ, Adams DH, Thursz MR, Wendon JA, Antoniades CG.

Gut. 2018 Jun;67(6):1155-1167. doi: 10.1136/gutjnl-2017-314184. Epub 2017 Jun 7.

19.

CD151 supports VCAM-1-mediated lymphocyte adhesion to liver endothelium and is upregulated in chronic liver disease and hepatocellular carcinoma.

Wadkin JCR, Patten DA, Kamarajah SK, Shepherd EL, Novitskaya V, Berditchevski F, Adams DH, Weston CJ, Shetty S.

Am J Physiol Gastrointest Liver Physiol. 2017 Aug 1;313(2):G138-G149. doi: 10.1152/ajpgi.00411.2016. Epub 2017 May 4.

20.

MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure.

Triantafyllou E, Pop OT, Possamai LA, Wilhelm A, Liaskou E, Singanayagam A, Bernsmeier C, Khamri W, Petts G, Dargue R, Davies SP, Tickle J, Yuksel M, Patel VC, Abeles RD, Stamataki Z, Curbishley SM, Ma Y, Wilson ID, Coen M, Woollard KJ, Quaglia A, Wendon J, Thursz MR, Adams DH, Weston CJ, Antoniades CG.

Gut. 2018 Feb;67(2):333-347. doi: 10.1136/gutjnl-2016-313615. Epub 2017 Apr 27.

21.

Vascular adhesion protein-1 is elevated in primary sclerosing cholangitis, is predictive of clinical outcome and facilitates recruitment of gut-tropic lymphocytes to liver in a substrate-dependent manner.

Trivedi PJ, Tickle J, Vesterhus MN, Eddowes PJ, Bruns T, Vainio J, Parker R, Smith D, Liaskou E, Thorbjørnsen LW, Hirschfield GM, Auvinen K, Hubscher SG, Salmi M, Adams DH, Weston CJ.

Gut. 2018 Jun;67(6):1135-1145. doi: 10.1136/gutjnl-2016-312354. Epub 2017 Apr 20.

22.

Increased Expression of Cytotoxic T-Lymphocyte-Associated Protein 4 by T Cells, Induced by B7 in Sera, Reduces Adaptive Immunity in Patients With Acute Liver Failure.

Khamri W, Abeles RD, Hou TZ, Anderson AE, El-Masry A, Triantafyllou E, Bernsmeier C, Larsen FS, Singanayagam A, Kudo N, Possamai LA, Lebosse F, Auzinger G, Bernal W, Willars C, Weston CJ, Lombardi G, Wendon J, Thursz M, Antoniades CG.

Gastroenterology. 2017 Jul;153(1):263-276.e8. doi: 10.1053/j.gastro.2017.03.023. Epub 2017 Mar 28.

23.

Rapid prediction of particulate, humus and resistant fractions of soil organic carbon in reforested lands using infrared spectroscopy.

Madhavan DB, Baldock JA, Read ZJ, Murphy SC, Cunningham SC, Perring MP, Herrmann T, Lewis T, Cavagnaro TR, England JR, Paul KI, Weston CJ, Baker TG.

J Environ Manage. 2017 May 15;193:290-299. doi: 10.1016/j.jenvman.2017.02.013. Epub 2017 Feb 21.

PMID:
28232243
24.

Mitotic control of human papillomavirus genome-containing cells is regulated by the function of the PDZ-binding motif of the E6 oncoprotein.

Marsh EK, Delury CP, Davies NJ, Weston CJ, Miah MAL, Banks L, Parish JL, Higgs MR, Roberts S.

Oncotarget. 2017 Mar 21;8(12):19491-19506. doi: 10.18632/oncotarget.14469.

25.

Human liver sinusoidal endothelial cells promote intracellular crawling of lymphocytes during recruitment: A new step in migration.

Patten DA, Wilson GK, Bailey D, Shaw RK, Jalkanen S, Salmi M, Rot A, Weston CJ, Adams DH, Shetty S.

Hepatology. 2017 Jan;65(1):294-309. doi: 10.1002/hep.28879. Epub 2016 Nov 25.

26.

Stabilin-1 expression defines a subset of macrophages that mediate tissue homeostasis and prevent fibrosis in chronic liver injury.

Rantakari P, Patten DA, Valtonen J, Karikoski M, Gerke H, Dawes H, Laurila J, Ohlmeier S, Elima K, Hübscher SG, Weston CJ, Jalkanen S, Adams DH, Salmi M, Shetty S.

Proc Natl Acad Sci U S A. 2016 Aug 16;113(33):9298-303. doi: 10.1073/pnas.1604780113. Epub 2016 Jul 29.

27.

Mid-infrared spectroscopy for rapid assessment of soil properties after land use change from pastures to Eucalyptus globulus plantations.

Madhavan DB, Kitching M, Mendham DS, Weston CJ, Baker TG.

J Environ Manage. 2016 Jun 15;175:67-75. doi: 10.1016/j.jenvman.2016.03.032. Epub 2016 Apr 1.

PMID:
27043775
28.

Interaction of TWEAK with Fn14 leads to the progression of fibrotic liver disease by directly modulating hepatic stellate cell proliferation.

Wilhelm A, Shepherd EL, Amatucci A, Munir M, Reynolds G, Humphreys E, Resheq Y, Adams DH, Hübscher S, Burkly LC, Weston CJ, Afford SC.

J Pathol. 2016 May;239(1):109-21. doi: 10.1002/path.4707. Epub 2016 Mar 29.

29.

Evaluation of serum and tissue levels of VAP-1 in colorectal cancer.

Ward ST, Weston CJ, Shepherd EL, Hejmadi R, Ismail T, Adams DH.

BMC Cancer. 2016 Feb 24;16:154. doi: 10.1186/s12885-016-2183-7.

30.

Intestinal CCL25 expression is increased in colitis and correlates with inflammatory activity.

Trivedi PJ, Bruns T, Ward S, Mai M, Schmidt C, Hirschfield GM, Weston CJ, Adams DH.

J Autoimmun. 2016 Apr;68:98-104. doi: 10.1016/j.jaut.2016.01.001. Epub 2016 Feb 9.

31.

Bidirectional transendothelial migration of monocytes across hepatic sinusoidal endothelium shapes monocyte differentiation and regulates the balance between immunity and tolerance in liver.

Zimmermann HW, Bruns T, Weston CJ, Curbishley SM, Liaskou E, Li KK, Resheq YJ, Badenhorst PW, Adams DH.

Hepatology. 2016 Jan;63(1):233-46. doi: 10.1002/hep.28285. Epub 2015 Nov 23.

32.

Cytoglobin expression in the hepatic stellate cell line HSC-T6 is regulated by extracellular matrix proteins dependent on FAK-signalling.

Stone LC, Thorne LS, Weston CJ, Graham M, Hodges NJ.

Fibrogenesis Tissue Repair. 2015 Aug 21;8:15. doi: 10.1186/s13069-015-0032-y. eCollection 2015.

33.

CD248/endosialin critically regulates hepatic stellate cell proliferation during chronic liver injury via a PDGF-regulated mechanism.

Wilhelm A, Aldridge V, Haldar D, Naylor AJ, Weston CJ, Hedegaard D, Garg A, Fear J, Reynolds GM, Croft AP, Henderson NC, Buckley CD, Newsome PN.

Gut. 2016 Jul;65(7):1175-85. doi: 10.1136/gutjnl-2014-308325. Epub 2015 Jun 15.

34.

Serum alkaline phosphatase in multidrug resistance 2 (Mdr2(-/-) ) knockout mice is strain specific.

Trivedi PJ, Weston CJ, Webb GJ, Newsome PN, Hirschfield GM, Adams DH.

Hepatology. 2016 Jan;63(1):346. doi: 10.1002/hep.27874. Epub 2015 Jun 26. No abstract available.

PMID:
25930031
35.

CMV infection of human sinusoidal endothelium regulates hepatic T cell recruitment and activation.

Bruns T, Zimmermann HW, Pachnio A, Li KK, Trivedi PJ, Reynolds G, Hubscher S, Stamataki Z, Badenhorst PW, Weston CJ, Moss PA, Adams DH.

J Hepatol. 2015 Jul;63(1):38-49. doi: 10.1016/j.jhep.2015.02.046. Epub 2015 Mar 12.

PMID:
25770658
36.

Contact-dependent depletion of hydrogen peroxide by catalase is a novel mechanism of myeloid-derived suppressor cell induction operating in human hepatic stellate cells.

Resheq YJ, Li KK, Ward ST, Wilhelm A, Garg A, Curbishley SM, Blahova M, Zimmermann HW, Jitschin R, Mougiakakos D, Mackensen A, Weston CJ, Adams DH.

J Immunol. 2015 Mar 15;194(6):2578-86. doi: 10.4049/jimmunol.1401046. Epub 2015 Feb 9.

37.

Vascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis.

Weston CJ, Shepherd EL, Claridge LC, Rantakari P, Curbishley SM, Tomlinson JW, Hubscher SG, Reynolds GM, Aalto K, Anstee QM, Jalkanen S, Salmi M, Smith DJ, Day CP, Adams DH.

J Clin Invest. 2015 Feb;125(2):501-20. doi: 10.1172/JCI73722. Epub 2014 Dec 22.

38.

Patients with acute-on-chronic liver failure have increased numbers of regulatory immune cells expressing the receptor tyrosine kinase MERTK.

Bernsmeier C, Pop OT, Singanayagam A, Triantafyllou E, Patel VC, Weston CJ, Curbishley S, Sadiq F, Vergis N, Khamri W, Bernal W, Auzinger G, Heneghan M, Ma Y, Jassem W, Heaton ND, Adams DH, Quaglia A, Thursz MR, Wendon J, Antoniades CG.

Gastroenterology. 2015 Mar;148(3):603-615.e14. doi: 10.1053/j.gastro.2014.11.045. Epub 2014 Dec 3.

PMID:
25479139
39.

The effects of CCR5 inhibition on regulatory T-cell recruitment to colorectal cancer.

Ward ST, Li KK, Hepburn E, Weston CJ, Curbishley SM, Reynolds GM, Hejmadi RK, Bicknell R, Eksteen B, Ismail T, Rot A, Adams DH.

Br J Cancer. 2015 Jan 20;112(2):319-28. doi: 10.1038/bjc.2014.572. Epub 2014 Nov 18.

40.
41.

Evaluation of serum lysyl oxidase as a blood test for colorectal cancer.

Ward ST, Weston CJ, Hepburn E, Damery S, Hejmadi RK, Morton DG, Middleton G, Ismail T, Adams DH.

Eur J Surg Oncol. 2014 Jun;40(6):731-8. doi: 10.1016/j.ejso.2013.10.023. Epub 2013 Nov 6.

42.

Cellular localization and trafficking of vascular adhesion protein-1 as revealed by an N-terminal GFP fusion protein.

Weston CJ, Shepherd EL, Adams DH.

J Neural Transm (Vienna). 2013 Jun;120(6):951-61. doi: 10.1007/s00702-013-1003-3. Epub 2013 Mar 9.

43.

Recruitment mechanisms of primary and malignant B cells to the human liver.

Shetty S, Bruns T, Weston CJ, Stamataki Z, Oo YH, Long HM, Reynolds GM, Pratt G, Moss P, Jalkanen S, Hubscher SG, Lalor PF, Adams DH.

Hepatology. 2012 Oct;56(4):1521-31. doi: 10.1002/hep.25790.

PMID:
22508288
44.

Autophagy: a cyto-protective mechanism which prevents primary human hepatocyte apoptosis during oxidative stress.

Bhogal RH, Weston CJ, Curbishley SM, Adams DH, Afford SC.

Autophagy. 2012 Apr;8(4):545-58. doi: 10.4161/auto.19012. Epub 2012 Apr 1.

45.

Activation of CD40 with platelet derived CD154 promotes reactive oxygen species dependent death of human hepatocytes during hypoxia and reoxygenation.

Bhogal RH, Weston CJ, Curbishley SM, Adams DH, Afford SC.

PLoS One. 2012;7(1):e30867. doi: 10.1371/journal.pone.0030867. Epub 2012 Jan 25.

46.

Hepatic consequences of vascular adhesion protein-1 expression.

Weston CJ, Adams DH.

J Neural Transm (Vienna). 2011 Jul;118(7):1055-64. doi: 10.1007/s00702-011-0647-0. Epub 2011 Apr 22. Review.

PMID:
21512782
47.

Isolation of primary human hepatocytes from normal and diseased liver tissue: a one hundred liver experience.

Bhogal RH, Hodson J, Bartlett DC, Weston CJ, Curbishley SM, Haughton E, Williams KT, Reynolds GM, Newsome PN, Adams DH, Afford SC.

PLoS One. 2011 Mar 29;6(3):e18222. doi: 10.1371/journal.pone.0018222.

48.

Common lymphatic endothelial and vascular endothelial receptor-1 mediates the transmigration of regulatory T cells across human hepatic sinusoidal endothelium.

Shetty S, Weston CJ, Oo YH, Westerlund N, Stamataki Z, Youster J, Hubscher SG, Salmi M, Jalkanen S, Lalor PF, Adams DH.

J Immunol. 2011 Apr 1;186(7):4147-55. doi: 10.4049/jimmunol.1002961. Epub 2011 Mar 2.

49.

Variable responses of small and large human hepatocytes to hypoxia and hypoxia/reoxygenation (H-R).

Bhogal RH, Weston CJ, Curbishley SM, Bhatt AN, Adams DH, Afford SC.

FEBS Lett. 2011 Mar 23;585(6):935-41. doi: 10.1016/j.febslet.2011.02.030. Epub 2011 Feb 25.

50.

Regulation of mucosal addressin cell adhesion molecule 1 expression in human and mice by vascular adhesion protein 1 amine oxidase activity.

Liaskou E, Karikoski M, Reynolds GM, Lalor PF, Weston CJ, Pullen N, Salmi M, Jalkanen S, Adams DH.

Hepatology. 2011 Feb;53(2):661-72. doi: 10.1002/hep.24085. Epub 2011 Jan 10.

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