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Items: 1 to 50 of 345

1.

Tautomeric G•U pairs within the molecular ribosomal grip and fidelity of decoding in bacteria.

Rozov A, Wolff P, Grosjean H, Yusupov M, Yusupova G, Westhof E.

Nucleic Acids Res. 2018 Jun 21. doi: 10.1093/nar/gky547. [Epub ahead of print]

PMID:
29931292
2.

Dimerization confers increased stability to nucleases in 5' halves from glycine and glutamic acid tRNAs.

Tosar JP, Gámbaro F, Darré L, Pantano S, Westhof E, Cayota A.

Nucleic Acids Res. 2018 Jun 11. doi: 10.1093/nar/gky495. [Epub ahead of print]

PMID:
29893896
3.

Mining for recurrent long-range interactions in RNA structures reveals embedded hierarchies in network families.

Reinharz V, Soulé A, Westhof E, Waldispühl J, Denise A.

Nucleic Acids Res. 2018 May 4;46(8):3841-3851. doi: 10.1093/nar/gky197.

4.

Mutations in signal recognition particle SRP54 cause syndromic neutropenia with Shwachman-Diamond-like features.

Carapito R, Konantz M, Paillard C, Miao Z, Pichot A, Leduc MS, Yang Y, Bergstrom KL, Mahoney DH, Shardy DL, Alsaleh G, Naegely L, Kolmer A, Paul N, Hanauer A, Rolli V, Müller JS, Alghisi E, Sauteur L, Macquin C, Morlon A, Sancho CS, Amati-Bonneau P, Procaccio V, Mosca-Boidron AL, Marle N, Osmani N, Lefebvre O, Goetz JG, Unal S, Akarsu NA, Radosavljevic M, Chenard MP, Rialland F, Grain A, Béné MC, Eveillard M, Vincent M, Guy J, Faivre L, Thauvin-Robinet C, Thevenon J, Myers K, Fleming MD, Shimamura A, Bottollier-Lemallaz E, Westhof E, Lengerke C, Isidor B, Bahram S.

J Clin Invest. 2017 Nov 1;127(11):4090-4103. doi: 10.1172/JCI92876. Epub 2017 Oct 3.

5.

Crystal structure and fluorescence properties of the iSpinach aptamer in complex with DFHBI.

Fernandez-Millan P, Autour A, Ennifar E, Westhof E, Ryckelynck M.

RNA. 2017 Dec;23(12):1788-1795. doi: 10.1261/rna.063008.117. Epub 2017 Sep 22.

6.

Recent Advances in Mitochondrial Aminoacyl-tRNA Synthetases and Disease.

Sissler M, González-Serrano LE, Westhof E.

Trends Mol Med. 2017 Aug;23(8):693-708. doi: 10.1016/j.molmed.2017.06.002. Epub 2017 Jul 14. Review.

7.

A novel double kink-turn module in euryarchaeal RNase P RNAs.

Lai LB, Tanimoto A, Lai SM, Chen WY, Marathe IA, Westhof E, Wysocki VH, Gopalan V.

Nucleic Acids Res. 2017 Jul 7;45(12):7432-7440. doi: 10.1093/nar/gkx388.

8.

RNA Structure: Advances and Assessment of 3D Structure Prediction.

Miao Z, Westhof E.

Annu Rev Biophys. 2017 May 22;46:483-503. doi: 10.1146/annurev-biophys-070816-034125. Epub 2017 Mar 30. Review.

PMID:
28375730
9.

RNA-Puzzles Round III: 3D RNA structure prediction of five riboswitches and one ribozyme.

Miao Z, Adamiak RW, Antczak M, Batey RT, Becka AJ, Biesiada M, Boniecki MJ, Bujnicki JM, Chen SJ, Cheng CY, Chou FC, Ferré-D'Amaré AR, Das R, Dawson WK, Ding F, Dokholyan NV, Dunin-Horkawicz S, Geniesse C, Kappel K, Kladwang W, Krokhotin A, Łach GE, Major F, Mann TH, Magnus M, Pachulska-Wieczorek K, Patel DJ, Piccirilli JA, Popenda M, Purzycka KJ, Ren A, Rice GM, Santalucia J Jr, Sarzynska J, Szachniuk M, Tandon A, Trausch JJ, Tian S, Wang J, Weeks KM, Williams B 2nd, Xiao Y, Xu X, Zhang D, Zok T, Westhof E.

RNA. 2017 May;23(5):655-672. doi: 10.1261/rna.060368.116. Epub 2017 Jan 30.

10.

Crystal structures of a group II intron lariat primed for reverse splicing.

Costa M, Walbott H, Monachello D, Westhof E, Michel F.

Science. 2016 Dec 2;354(6316). pii: aaf9258.

PMID:
27934709
11.

An integrated, structure- and energy-based view of the genetic code.

Grosjean H, Westhof E.

Nucleic Acids Res. 2016 Sep 30;44(17):8020-40. doi: 10.1093/nar/gkw608. Epub 2016 Jul 22. Review.

12.

New Structural Insights into Translational Miscoding.

Rozov A, Demeshkina N, Westhof E, Yusupov M, Yusupova G.

Trends Biochem Sci. 2016 Sep;41(9):798-814. doi: 10.1016/j.tibs.2016.06.001. Epub 2016 Jun 30. Review.

PMID:
27372401
13.

Supporting breast-feeding women from the perspective of the midwife: A systematic review of the literature.

Swerts M, Westhof E, Bogaerts A, Lemiengre J.

Midwifery. 2016 Jun;37:32-40. doi: 10.1016/j.midw.2016.02.016. Epub 2016 Mar 4. Review.

PMID:
27217235
14.

The ribosome prohibits the G•U wobble geometry at the first position of the codon-anticodon helix.

Rozov A, Westhof E, Yusupov M, Yusupova G.

Nucleic Acids Res. 2016 Jul 27;44(13):6434-41. doi: 10.1093/nar/gkw431. Epub 2016 May 12.

15.

RBscore&NBench: a high-level web server for nucleic acid binding residues prediction with a large-scale benchmarking database.

Miao Z, Westhof E.

Nucleic Acids Res. 2016 Jul 8;44(W1):W562-7. doi: 10.1093/nar/gkw251. Epub 2016 Apr 15.

16.

iSpinach: a fluorogenic RNA aptamer optimized for in vitro applications.

Autour A, Westhof E, Ryckelynck M.

Nucleic Acids Res. 2016 Apr 7;44(6):2491-500. doi: 10.1093/nar/gkw083. Epub 2016 Mar 1.

17.

Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code.

Rozov A, Demeshkina N, Khusainov I, Westhof E, Yusupov M, Yusupova G.

Nat Commun. 2016 Jan 21;7:10457. doi: 10.1038/ncomms10457.

18.

A Large-Scale Assessment of Nucleic Acids Binding Site Prediction Programs.

Miao Z, Westhof E.

PLoS Comput Biol. 2015 Dec 17;11(12):e1004639. doi: 10.1371/journal.pcbi.1004639. eCollection 2015 Dec.

19.

RNA structure from deep sequencing.

Westhof E.

Nat Biotechnol. 2015 Sep;33(9):928-9. doi: 10.1038/nbt.3338. No abstract available.

PMID:
26348961
20.

Perspectives and Pitfalls in Nucleic Acids Crystallography.

Westhof E.

Methods Mol Biol. 2016;1320:3-8. doi: 10.1007/978-1-4939-2763-0_1.

PMID:
26227033
21.

Structural insights into the translational infidelity mechanism.

Rozov A, Demeshkina N, Westhof E, Yusupov M, Yusupova G.

Nat Commun. 2015 Jun 3;6:7251. doi: 10.1038/ncomms8251.

22.

Prediction of nucleic acid binding probability in proteins: a neighboring residue network based score.

Miao Z, Westhof E.

Nucleic Acids Res. 2015 Jun 23;43(11):5340-51. doi: 10.1093/nar/gkv446. Epub 2015 May 4.

23.

RNA-Puzzles Round II: assessment of RNA structure prediction programs applied to three large RNA structures.

Miao Z, Adamiak RW, Blanchet MF, Boniecki M, Bujnicki JM, Chen SJ, Cheng C, Chojnowski G, Chou FC, Cordero P, Cruz JA, Ferré-D'Amaré AR, Das R, Ding F, Dokholyan NV, Dunin-Horkawicz S, Kladwang W, Krokhotin A, Lach G, Magnus M, Major F, Mann TH, Masquida B, Matelska D, Meyer M, Peselis A, Popenda M, Purzycka KJ, Serganov A, Stasiewicz J, Szachniuk M, Tandon A, Tian S, Wang J, Xiao Y, Xu X, Zhang J, Zhao P, Zok T, Westhof E.

RNA. 2015 Jun;21(6):1066-84. doi: 10.1261/rna.049502.114. Epub 2015 Apr 16.

24.

Twenty years of RNA crystallography.

Westhof E.

RNA. 2015 Apr;21(4):486-7. doi: 10.1261/rna.049726.115. No abstract available.

25.

Using droplet-based microfluidics to improve the catalytic properties of RNA under multiple-turnover conditions.

Ryckelynck M, Baudrey S, Rick C, Marin A, Coldren F, Westhof E, Griffiths AD.

RNA. 2015 Mar;21(3):458-69. doi: 10.1261/rna.048033.114. Epub 2015 Jan 20.

26.

In-line alignment and Mg²⁺ coordination at the cleavage site of the env22 twister ribozyme.

Ren A, Košutić M, Rajashankar KR, Frener M, Santner T, Westhof E, Micura R, Patel DJ.

Nat Commun. 2014 Nov 20;5:5534. doi: 10.1038/ncomms6534.

27.

Biogenesis of Circular RNAs.

Vicens Q, Westhof E.

Cell. 2014 Sep 25;159(1):13-14. doi: 10.1016/j.cell.2014.09.005.

28.

Chemistry. Self-assembled RNA nanostructures.

Leontis NB, Westhof E.

Science. 2014 Aug 15;345(6198):732-3. doi: 10.1126/science.1257989. No abstract available.

PMID:
25124412
29.

Isostericity and tautomerism of base pairs in nucleic acids.

Westhof E.

FEBS Lett. 2014 Aug 1;588(15):2464-9. doi: 10.1016/j.febslet.2014.06.031. Epub 2014 Jun 17. Review.

30.

The complete genome of Blastobotrys (Arxula) adeninivorans LS3 - a yeast of biotechnological interest.

Kunze G, Gaillardin C, Czernicka M, Durrens P, Martin T, Böer E, Gabaldón T, Cruz JA, Talla E, Marck C, Goffeau A, Barbe V, Baret P, Baronian K, Beier S, Bleykasten C, Bode R, Casaregola S, Despons L, Fairhead C, Giersberg M, Gierski PP, Hähnel U, Hartmann A, Jankowska D, Jubin C, Jung P, Lafontaine I, Leh-Louis V, Lemaire M, Marcet-Houben M, Mascher M, Morel G, Richard GF, Riechen J, Sacerdot C, Sarkar A, Savel G, Schacherer J, Sherman DJ, Stein N, Straub ML, Thierry A, Trautwein-Schult A, Vacherie B, Westhof E, Worch S, Dujon B, Souciet JL, Wincker P, Scholz U, Neuvéglise C.

Biotechnol Biofuels. 2014 Apr 24;7:66. doi: 10.1186/1754-6834-7-66. eCollection 2014.

31.

Speciation of a group I intron into a lariat capping ribozyme.

Meyer M, Nielsen H, Oliéric V, Roblin P, Johansen SD, Westhof E, Masquida B.

Proc Natl Acad Sci U S A. 2014 May 27;111(21):7659-64. doi: 10.1073/pnas.1322248111. Epub 2014 May 12.

32.

Recognition of Watson-Crick base pairs: constraints and limits due to geometric selection and tautomerism.

Westhof E, Yusupov M, Yusupova G.

F1000Prime Rep. 2014 Apr 1;6:19. doi: 10.12703/P6-19. eCollection 2014. Review.

33.

A PNPase dependent CRISPR System in Listeria.

Sesto N, Touchon M, Andrade JM, Kondo J, Rocha EP, Arraiano CM, Archambaud C, Westhof É, Romby P, Cossart P.

PLoS Genet. 2014 Jan;10(1):e1004065. doi: 10.1371/journal.pgen.1004065. Epub 2014 Jan 9.

34.

Specific features of telomerase RNA from Hansenula polymorpha.

Smekalova EM, Malyavko AN, Zvereva MI, Mardanov AV, Ravin NV, Skryabin KG, Westhof E, Dontsova OA.

RNA. 2013 Nov;19(11):1563-74. doi: 10.1261/rna.038612.113. Epub 2013 Sep 17.

35.

Comparative genomics of emerging pathogens in the Candida glabrata clade.

Gabaldón T, Martin T, Marcet-Houben M, Durrens P, Bolotin-Fukuhara M, Lespinet O, Arnaise S, Boisnard S, Aguileta G, Atanasova R, Bouchier C, Couloux A, Creno S, Almeida Cruz J, Devillers H, Enache-Angoulvant A, Guitard J, Jaouen L, Ma L, Marck C, Neuvéglise C, Pelletier E, Pinard A, Poulain J, Recoquillay J, Westhof E, Wincker P, Dujon B, Hennequin C, Fairhead C.

BMC Genomics. 2013 Sep 14;14:623. doi: 10.1186/1471-2164-14-623.

36.

RNA structure analysis of human spliceosomes reveals a compact 3D arrangement of snRNAs at the catalytic core.

Anokhina M, Bessonov S, Miao Z, Westhof E, Hartmuth K, Lührmann R.

EMBO J. 2013 Oct 30;32(21):2804-18. doi: 10.1038/emboj.2013.198. Epub 2013 Sep 3.

37.

Structure-activity relationships of saponins enhancing the cytotoxicity of ribosome-inactivating proteins type I (RIP-I).

Böttger S, Westhof E, Siems K, Melzig MF.

Toxicon. 2013 Oct;73:144-50. doi: 10.1016/j.toxicon.2013.07.011. Epub 2013 Jul 25.

PMID:
23891686
38.

Structure of an A-form RNA duplex obtained by degradation of 6S RNA in a crystallization droplet.

Kondo J, Dock-Bregeon AC, Willkomm DK, Hartmann RK, Westhof E.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Jun;69(Pt 6):634-9. doi: 10.1107/S1744309113013018. Epub 2013 May 24.

39.

New structural insights into the decoding mechanism: translation infidelity via a G·U pair with Watson-Crick geometry.

Demeshkina N, Jenner L, Westhof E, Yusupov M, Yusupova G.

FEBS Lett. 2013 Jun 27;587(13):1848-57. doi: 10.1016/j.febslet.2013.05.009. Epub 2013 May 23. Review.

40.

High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome.

Hashem Y, des Georges A, Fu J, Buss SN, Jossinet F, Jobe A, Zhang Q, Liao HY, Grassucci RA, Bajaj C, Westhof E, Madison-Antenucci S, Frank J.

Nature. 2013 Feb 21;494(7437):385-9. doi: 10.1038/nature11872. Epub 2013 Feb 10.

41.

Transcriptome-wide identification of A > I RNA editing sites by inosine specific cleavage.

Cattenoz PB, Taft RJ, Westhof E, Mattick JS.

RNA. 2013 Feb;19(2):257-70. doi: 10.1261/rna.036202.112. Epub 2012 Dec 21.

42.

Loop-loop interactions involved in antisense regulation are processed by the endoribonuclease III in Staphylococcus aureus.

Romilly C, Chevalier C, Marzi S, Masquida B, Geissmann T, Vandenesch F, Westhof E, Romby P.

RNA Biol. 2012 Dec;9(12):1461-72. doi: 10.4161/rna.22710. Epub 2012 Nov 7.

PMID:
23134978
43.

Structure-activity relationships among the kanamycin aminoglycosides: role of ring I hydroxyl and amino groups.

Salian S, Matt T, Akbergenov R, Harish S, Meyer M, Duscha S, Shcherbakov D, Bernet BB, Vasella A, Westhof E, Böttger EC.

Antimicrob Agents Chemother. 2012 Dec;56(12):6104-8. doi: 10.1128/AAC.01326-12. Epub 2012 Sep 4.

44.

A new understanding of the decoding principle on the ribosome.

Demeshkina N, Jenner L, Westhof E, Yusupov M, Yusupova G.

Nature. 2012 Mar 21;484(7393):256-9. doi: 10.1038/nature10913.

PMID:
22437501
45.

Mutation in a primate-conserved retrotransposon reveals a noncoding RNA as a mediator of infantile encephalopathy.

Cartault F, Munier P, Benko E, Desguerre I, Hanein S, Boddaert N, Bandiera S, Vellayoudom J, Krejbich-Trotot P, Bintner M, Hoarau JJ, Girard M, Génin E, de Lonlay P, Fourmaintraux A, Naville M, Rodriguez D, Feingold J, Renouil M, Munnich A, Westhof E, Fähling M, Lyonnet S, Henrion-Caude A.

Proc Natl Acad Sci U S A. 2012 Mar 27;109(13):4980-5. doi: 10.1073/pnas.1111596109. Epub 2012 Mar 12.

46.

Pichia sorbitophila, an Interspecies Yeast Hybrid, Reveals Early Steps of Genome Resolution After Polyploidization.

Louis VL, Despons L, Friedrich A, Martin T, Durrens P, Casarégola S, Neuvéglise C, Fairhead C, Marck C, Cruz JA, Straub ML, Kugler V, Sacerdot C, Uzunov Z, Thierry A, Weiss S, Bleykasten C, De Montigny J, Jacques N, Jung P, Lemaire M, Mallet S, Morel G, Richard GF, Sarkar A, Savel G, Schacherer J, Seret ML, Talla E, Samson G, Jubin C, Poulain J, Vacherie B, Barbe V, Pelletier E, Sherman DJ, Westhof E, Weissenbach J, Baret PV, Wincker P, Gaillardin C, Dujon B, Souciet JL.

G3 (Bethesda). 2012 Feb;2(2):299-311. doi: 10.1534/g3.111.000745. Epub 2012 Feb 1.

47.

RNA-Puzzles: a CASP-like evaluation of RNA three-dimensional structure prediction.

Cruz JA, Blanchet MF, Boniecki M, Bujnicki JM, Chen SJ, Cao S, Das R, Ding F, Dokholyan NV, Flores SC, Huang L, Lavender CA, Lisi V, Major F, Mikolajczak K, Patel DJ, Philips A, Puton T, Santalucia J, Sijenyi F, Hermann T, Rother K, Rother M, Serganov A, Skorupski M, Soltysinski T, Sripakdeevong P, Tuszynska I, Weeks KM, Waldsich C, Wildauer M, Leontis NB, Westhof E.

RNA. 2012 Apr;18(4):610-25. doi: 10.1261/rna.031054.111. Epub 2012 Feb 23.

48.

A structural module in RNase P expands the variety of RNA kinks.

Meyer M, Westhof E, Masquida B.

RNA Biol. 2012 Mar;9(3):254-60. doi: 10.4161/rna.19434. Epub 2012 Mar 1.

PMID:
22336704
49.

Automated prediction of three-way junction topological families in RNA secondary structures.

Lamiable A, Barth D, Denise A, Quessette F, Vial S, Westhof E.

Comput Biol Chem. 2012 Apr;37:1-5. doi: 10.1016/j.compbiolchem.2011.11.001. Epub 2012 Jan 11.

PMID:
22326420
50.

Ribozymes, catalytically active RNA molecules. Introduction.

Westhof E.

Methods Mol Biol. 2012;848:1-4. doi: 10.1007/978-1-61779-545-9_1.

PMID:
22315059

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