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Items: 11

1.

Isolation and structure-function characterization of a signaling-active rhodopsin-G protein complex.

Gao Y, Westfield G, Erickson JW, Cerione RA, Skiniotis G, Ramachandran S.

J Biol Chem. 2017 Aug 25;292(34):14280-14289. doi: 10.1074/jbc.M117.797100. Epub 2017 Jun 27.

2.

Visualization of arrestin recruitment by a G-protein-coupled receptor.

Shukla AK, Westfield GH, Xiao K, Reis RI, Huang LY, Tripathi-Shukla P, Qian J, Li S, Blanc A, Oleskie AN, Dosey AM, Su M, Liang CR, Gu LL, Shan JM, Chen X, Hanna R, Choi M, Yao XJ, Klink BU, Kahsai AW, Sidhu SS, Koide S, Penczek PA, Kossiakoff AA, Woods VL Jr, Kobilka BK, Skiniotis G, Lefkowitz RJ.

Nature. 2014 Aug 14;512(7513):218-222. doi: 10.1038/nature13430. Epub 2014 Jun 22.

3.

Context dependency of Set1/COMPASS-mediated histone H3 Lys4 trimethylation.

Thornton JL, Westfield GH, Takahashi YH, Cook M, Gao X, Woodfin AR, Lee JS, Morgan MA, Jackson J, Smith ER, Couture JF, Skiniotis G, Shilatifard A.

Genes Dev. 2014 Jan 15;28(2):115-20. doi: 10.1101/gad.232215.113. Epub 2014 Jan 8.

4.

Ligand-induced architecture of the leptin receptor signaling complex.

Mancour LV, Daghestani HN, Dutta S, Westfield GH, Schilling J, Oleskie AN, Herbstman JF, Chou SZ, Skiniotis G.

Mol Cell. 2012 Nov 30;48(4):655-61. doi: 10.1016/j.molcel.2012.09.003. Epub 2012 Oct 11.

5.

Structural analysis of the core COMPASS family of histone H3K4 methylases from yeast to human.

Takahashi YH, Westfield GH, Oleskie AN, Trievel RC, Shilatifard A, Skiniotis G.

Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20526-31. doi: 10.1073/pnas.1109360108. Epub 2011 Dec 7.

6.

Structural flexibility of the G alpha s alpha-helical domain in the beta2-adrenoceptor Gs complex.

Westfield GH, Rasmussen SG, Su M, Dutta S, DeVree BT, Chung KY, Calinski D, Velez-Ruiz G, Oleskie AN, Pardon E, Chae PS, Liu T, Li S, Woods VL Jr, Steyaert J, Kobilka BK, Sunahara RK, Skiniotis G.

Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):16086-91. doi: 10.1073/pnas.1113645108. Epub 2011 Sep 13.

7.

A hypomorphic Artemis human disease allele causes aberrant chromosomal rearrangements and tumorigenesis.

Jacobs C, Huang Y, Masud T, Lu W, Westfield G, Giblin W, Sekiguchi JM.

Hum Mol Genet. 2011 Feb 15;20(4):806-19. doi: 10.1093/hmg/ddq524. Epub 2010 Dec 8.

8.

Switch recombination and somatic hypermutation are controlled by the heavy chain 3' enhancer region.

Dunnick WA, Collins JT, Shi J, Westfield G, Fontaine C, Hakimpour P, Papavasiliou FN.

J Exp Med. 2009 Nov 23;206(12):2613-23. doi: 10.1084/jem.20091280. Epub 2009 Nov 2.

9.

Impact of a hypomorphic Artemis disease allele on lymphocyte development, DNA end processing, and genome stability.

Huang Y, Giblin W, Kubec M, Westfield G, St Charles J, Chadde L, Kraftson S, Sekiguchi J.

J Exp Med. 2009 Apr 13;206(4):893-908. doi: 10.1084/jem.20082396. Epub 2009 Apr 6.

10.

Leaky severe combined immunodeficiency and aberrant DNA rearrangements due to a hypomorphic RAG1 mutation.

Giblin W, Chatterji M, Westfield G, Masud T, Theisen B, Cheng HL, DeVido J, Alt FW, Ferguson DO, Schatz DG, Sekiguchi J.

Blood. 2009 Mar 26;113(13):2965-75. doi: 10.1182/blood-2008-07-165167. Epub 2009 Jan 6.

11.

Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation.

Buis J, Wu Y, Deng Y, Leddon J, Westfield G, Eckersdorff M, Sekiguchi JM, Chang S, Ferguson DO.

Cell. 2008 Oct 3;135(1):85-96. doi: 10.1016/j.cell.2008.08.015.

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