Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 35

1.

Scientific evidence for pelvic floor devices presented at conferences: An overview.

Te Brummelstroete GH, Loohuis AM, Wessels NJ, Westers HC, van Summeren JJGT, Blanker MH.

Neurourol Urodyn. 2019 Sep;38(7):1958-1965. doi: 10.1002/nau.24099. Epub 2019 Jul 8.

2.

Comprehensive Profiling of Primary and Metastatic ccRCC Reveals a High Homology of the Metastases to a Subregion of the Primary Tumour.

Ferronika P, Hof J, Kats-Ugurlu G, Sijmons RH, Terpstra MM, de Lange K, Leliveld-Kors A, Westers H, Kok K.

Cancers (Basel). 2019 Jun 12;11(6). pii: E812. doi: 10.3390/cancers11060812.

3.

A functional assay-based procedure to classify mismatch repair gene variants in Lynch syndrome.

Drost M, Tiersma Y, Thompson BA, Frederiksen JH, Keijzers G, Glubb D, Kathe S, Osinga J, Westers H, Pappas L, Boucher KM, Molenkamp S, Zonneveld JB, van Asperen CJ, Goldgar DE, Wallace SS, Sijmons RH, Spurdle AB, Rasmussen LJ, Greenblatt MS, de Wind N, Tavtigian SV.

Genet Med. 2019 Jul;21(7):1486-1496. doi: 10.1038/s41436-018-0372-2. Epub 2018 Dec 3.

PMID:
30504929
4.

Functional Studies on Primary Tubular Epithelial Cells Indicate a Tumor Suppressor Role of SETD2 in Clear Cell Renal Cell Carcinoma.

Li J, Kluiver J, Osinga J, Westers H, van Werkhoven MB, Seelen MA, Sijmons RH, van den Berg A, Kok K.

Neoplasia. 2016 Jun;18(6):339-46. doi: 10.1016/j.neo.2016.04.005. Epub 2016 May 26.

5.

SETD2: an epigenetic modifier with tumor suppressor functionality.

Li J, Duns G, Westers H, Sijmons R, van den Berg A, Kok K.

Oncotarget. 2016 Aug 2;7(31):50719-50734. doi: 10.18632/oncotarget.9368. Review.

6.

Correspondence: SEMA4A variation and risk of colorectal cancer.

Kinnersley B, Chubb D, Dobbins SE, Frampton M, Buch S, Timofeeva MN, Castellví-Bel S, Farrington SM, Forsti A, Hampe J, Hemminki K, Hofstra RM, Northwood E, Palles C, Pinheiro M, Ruiz-Ponte C, Schafmayer C, Teixeira MR, Westers H, van Wezel T, Timothy Bishop D, Tomlinson I, Dunlop MG, Houlston RS.

Nat Commun. 2016 Mar 10;7:10611. doi: 10.1038/ncomms10611. No abstract available.

7.

CoNVaDING: Single Exon Variation Detection in Targeted NGS Data.

Johansson LF, van Dijk F, de Boer EN, van Dijk-Bos KK, Jongbloed JD, van der Hout AH, Westers H, Sinke RJ, Swertz MA, Sijmons RH, Sikkema-Raddatz B.

Hum Mutat. 2016 May;37(5):457-64. doi: 10.1002/humu.22969. Epub 2016 Feb 24.

PMID:
26864275
8.

Recurrent Coding Sequence Variation Explains Only A Small Fraction of the Genetic Architecture of Colorectal Cancer.

Timofeeva MN, Kinnersley B, Farrington SM, Whiffin N, Palles C, Svinti V, Lloyd A, Gorman M, Ooi LY, Hosking F, Barclay E, Zgaga L, Dobbins S, Martin L, Theodoratou E, Broderick P, Tenesa A, Smillie C, Grimes G, Hayward C, Campbell A, Porteous D, Deary IJ, Harris SE, Northwood EL, Barrett JH, Smith G, Wolf R, Forman D, Morreau H, Ruano D, Tops C, Wijnen J, Schrumpf M, Boot A, Vasen HF, Hes FJ, van Wezel T, Franke A, Lieb W, Schafmayer C, Hampe J, Buch S, Propping P, Hemminki K, Försti A, Westers H, Hofstra R, Pinheiro M, Pinto C, Teixeira M, Ruiz-Ponte C, Fernández-Rozadilla C, Carracedo A, Castells A, Castellví-Bel S, Campbell H, Bishop DT, Tomlinson IP, Dunlop MG, Houlston RS.

Sci Rep. 2015 Nov 10;5:16286. doi: 10.1038/srep16286.

9.

New target genes in endometrial tumors show a role for the estrogen-receptor pathway in microsatellite-unstable cancers.

Ferreira AM, Tuominen I, Sousa S, Gerbens F, van Dijk-Bos K, Osinga J, Kooi KA, Sanjabi B, Esendam C, Oliveira C, Terpstra P, Hardonk M, van der Sluis T, Zazula M, Stachura J, van der Zee AG, Hollema H, Sijmons RH, Aaltonen LA, Seruca R, Hofstra RM, Westers H.

Hum Mutat. 2014 Dec;35(12):1514-23. doi: 10.1002/humu.22700.

PMID:
25231886
10.

High frequency of RPL22 mutations in microsatellite-unstable colorectal and endometrial tumors.

Ferreira AM, Tuominen I, van Dijk-Bos K, Sanjabi B, van der Sluis T, van der Zee AG, Hollema H, Zazula M, Sijmons RH, Aaltonen LA, Westers H, Hofstra RM.

Hum Mutat. 2014 Dec;35(12):1442-5. doi: 10.1002/humu.22686.

PMID:
25196364
11.

Re: Role of the oxidative DNA damage repair gene OGG1 in colorectal tumorigenesis.

Kinnersley B, Buch S, Castellví-Bel S, Farrington SM, Forsti A, Hampe J, Hemminki K, Hofstra RM, Northwood E, Palles C, Pinheiro M, Ruiz-Ponte C, Schafmayer C, Teixeira MR, Westers H, Wezel Tv, Bishop DT, Tomlinson I, Dunlop MG, Houlston RS.

J Natl Cancer Inst. 2014 Apr 26;106(5). pii: dju086. doi: 10.1093/jnci/dju086. No abstract available.

12.

The MLH1 c.1852_1853delinsGC (p.K618A) variant in colorectal cancer: genetic association study in 18,723 individuals.

Abulí A, Bujanda L, Muñoz J, Buch S, Schafmayer C, Valeria Maiorana M, Veneroni S, van Wezel T, Liu T, Westers H, Esteban-Jurado C, Ocaña T, Piqué JM, Andreu M, Jover R, Carracedo A, Xicola RM, Llor X, Castells A; EPICOLON Consortium, Dunlop M, Hofstra R, Lindblom A, Wijnen J, Peterlongo P, Hampe J, Ruiz-Ponte C, Castellví-Bel S.

PLoS One. 2014 Apr 17;9(4):e95022. doi: 10.1371/journal.pone.0095022. eCollection 2014.

13.

CLMP is essential for intestinal development, but does not play a key role in cellular processes involved in intestinal epithelial development.

van der Werf CS, Hsiao NH, Conroy S, Paredes J, Ribeiro AS, Sribudiani Y, Seruca R, Hofstra RM, Westers H, van Ijzendoorn SC.

PLoS One. 2013;8(2):e54649. doi: 10.1371/journal.pone.0054649. Epub 2013 Feb 27.

14.

Contribution of bi-allelic germline MUTYH mutations to early-onset and familial colorectal cancer and to low number of adenomatous polyps: case-series and literature review.

Knopperts AP, Nielsen M, Niessen RC, Tops CM, Jorritsma B, Varkevisser J, Wijnen J, Siezen CL, Heine-Bröring RC, van Kranen HJ, Vos YJ, Westers H, Kampman E, Sijmons RH, Hes FJ.

Fam Cancer. 2013 Mar;12(1):43-50. doi: 10.1007/s10689-012-9570-2. Review.

PMID:
23007840
15.

Functional analysis of the sortase YhcS in Bacillus subtilis.

Fasehee H, Westers H, Bolhuis A, Antelmann H, Hecker M, Quax WJ, Mirlohi AF, van Dijl JM, Ahmadian G.

Proteomics. 2011 Oct;11(19):3905-13. doi: 10.1002/pmic.201100174. Epub 2011 Aug 31.

PMID:
21800427
16.

A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3).

Enciso-Mora V, Broderick P, Ma Y, Jarrett RF, Hjalgrim H, Hemminki K, van den Berg A, Olver B, Lloyd A, Dobbins SE, Lightfoot T, van Leeuwen FE, Försti A, Diepstra A, Broeks A, Vijayakrishnan J, Shield L, Lake A, Montgomery D, Roman E, Engert A, von Strandmann EP, Reiners KS, Nolte IM, Smedby KE, Adami HO, Russell NS, Glimelius B, Hamilton-Dutoit S, de Bruin M, Ryder LP, Molin D, Sorensen KM, Chang ET, Taylor M, Cooke R, Hofstra R, Westers H, van Wezel T, van Eijk R, Ashworth A, Rostgaard K, Melbye M, Swerdlow AJ, Houlston RS.

Nat Genet. 2010 Dec;42(12):1126-1130. doi: 10.1038/ng.696. Epub 2010 Oct 31.

17.

Estrogens, MSI and Lynch syndrome-associated tumors.

Ferreira AM, Westers H, Albergaria A, Seruca R, Hofstra RM.

Biochim Biophys Acta. 2009 Dec;1796(2):194-200. doi: 10.1016/j.bbcan.2009.06.004. Epub 2009 Jun 25. Review.

PMID:
19559756
18.

Mononucleotide precedes dinucleotide repeat instability during colorectal tumour development in Lynch syndrome patients.

Ferreira AM, Westers H, Sousa S, Wu Y, Niessen RC, Olderode-Berends M, van der Sluis T, Reuvekamp PT, Seruca R, Kleibeuker JH, Hollema H, Sijmons RH, Hofstra RM.

J Pathol. 2009 Sep;219(1):96-102. doi: 10.1002/path.2573.

PMID:
19521971
19.

Germline hypermethylation of MLH1 and EPCAM deletions are a frequent cause of Lynch syndrome.

Niessen RC, Hofstra RM, Westers H, Ligtenberg MJ, Kooi K, Jager PO, de Groote ML, Dijkhuizen T, Olderode-Berends MJ, Hollema H, Kleibeuker JH, Sijmons RH.

Genes Chromosomes Cancer. 2009 Aug;48(8):737-44. doi: 10.1002/gcc.20678.

PMID:
19455606
20.

Do microsatellite instability profiles really differ between colorectal and endometrial tumors?

Ferreira AM, Westers H, Wu Y, Niessen RC, Olderode-Berends M, van der Sluis T, van der Zee AG, Hollema H, Kleibeuker JH, Sijmons RH, Hofstra RM.

Genes Chromosomes Cancer. 2009 Jul;48(7):552-7. doi: 10.1002/gcc.20664.

PMID:
19373783
21.

Biochemical characterization of MLH3 missense mutations does not reveal an apparent role of MLH3 in Lynch syndrome.

Ou J, Rasmussen M, Westers H, Andersen SD, Jager PO, Kooi KA, Niessen RC, Eggen BJ, Nielsen FC, Kleibeuker JH, Sijmons RH, Rasmussen LJ, Hofstra RM.

Genes Chromosomes Cancer. 2009 Apr;48(4):340-50. doi: 10.1002/gcc.20644.

PMID:
19156873
22.

PMS2 involvement in patients suspected of Lynch syndrome.

Niessen RC, Kleibeuker JH, Westers H, Jager PO, Rozeveld D, Bos KK, Boersma-van Ek W, Hollema H, Sijmons RH, Hofstra RM.

Genes Chromosomes Cancer. 2009 Apr;48(4):322-9. doi: 10.1002/gcc.20642.

PMID:
19132747
23.

A database to support the interpretation of human mismatch repair gene variants.

Ou J, Niessen RC, Vonk J, Westers H, Hofstra RM, Sijmons RH.

Hum Mutat. 2008 Nov;29(11):1337-41. doi: 10.1002/humu.20907.

PMID:
18951442
24.

Genetic or chemical protease inhibition causes significant changes in the Bacillus subtilis exoproteome.

Westers L, Westers H, Zanen G, Antelmann H, Hecker M, Noone D, Devine KM, van Dijl JM, Quax WJ.

Proteomics. 2008 Jul;8(13):2704-13. doi: 10.1002/pmic.200800009.

PMID:
18546160
25.

Iron starvation triggers the stringent response and induces amino acid biosynthesis for bacillibactin production in Bacillus subtilis.

Miethke M, Westers H, Blom EJ, Kuipers OP, Marahiel MA.

J Bacteriol. 2006 Dec;188(24):8655-7. Epub 2006 Sep 29.

26.

The CssRS two-component regulatory system controls a general secretion stress response in Bacillus subtilis.

Westers H, Westers L, Darmon E, van Dijl JM, Quax WJ, Zanen G.

FEBS J. 2006 Aug;273(16):3816-27.

27.

Secretion of functional human interleukin-3 from Bacillus subtilis.

Westers L, Dijkstra DS, Westers H, van Dijl JM, Quax WJ.

J Biotechnol. 2006 May 17;123(2):211-24. Epub 2005 Dec 15.

PMID:
16359746
28.

Signal peptide hydrophobicity is critical for early stages in protein export by Bacillus subtilis.

Zanen G, Houben EN, Meima R, Tjalsma H, Jongbloed JD, Westers H, Oudega B, Luirink J, van Dijl JM, Quax WJ.

FEBS J. 2005 Sep;272(18):4617-30.

29.

Genes involved in SkfA killing factor production protect a Bacillus subtilis lipase against proteolysis.

Westers H, Braun PG, Westers L, Antelmann H, Hecker M, Jongbloed JD, Yoshikawa H, Tanaka T, van Dijl JM, Quax WJ.

Appl Environ Microbiol. 2005 Apr;71(4):1899-908.

30.

Bacillus subtilis as cell factory for pharmaceutical proteins: a biotechnological approach to optimize the host organism.

Westers L, Westers H, Quax WJ.

Biochim Biophys Acta. 2004 Nov 11;1694(1-3):299-310. Review.

31.

FlhF, the third signal recognition particle-GTPase of Bacillus subtilis, is dispensable for protein secretion.

Zanen G, Antelmann H, Westers H, Hecker M, van Dijl JM, Quax WJ.

J Bacteriol. 2004 Sep;186(17):5956-60.

32.

The Bacillus secretion stress response is an indicator for alpha-amylase production levels.

Westers H, Darmon E, Zanen G, Veening JW, Kuipers OP, Bron S, Quax WJ, van Dijl JM.

Lett Appl Microbiol. 2004;39(1):65-73.

33.

Proteomics of protein secretion by Bacillus subtilis: separating the "secrets" of the secretome.

Tjalsma H, Antelmann H, Jongbloed JD, Braun PG, Darmon E, Dorenbos R, Dubois JY, Westers H, Zanen G, Quax WJ, Kuipers OP, Bron S, Hecker M, van Dijl JM.

Microbiol Mol Biol Rev. 2004 Jun;68(2):207-33. Review.

34.

Genome engineering reveals large dispensable regions in Bacillus subtilis.

Westers H, Dorenbos R, van Dijl JM, Kabel J, Flanagan T, Devine KM, Jude F, Seror SJ, Beekman AC, Darmon E, Eschevins C, de Jong A, Bron S, Kuipers OP, Albertini AM, Antelmann H, Hecker M, Zamboni N, Sauer U, Bruand C, Ehrlich DS, Alonso JC, Salas M, Quax WJ.

Mol Biol Evol. 2003 Dec;20(12):2076-90. Epub 2003 Aug 29.

PMID:
12949151
35.

The extracellular proteome of Bacillus subtilis under secretion stress conditions.

Antelmann H, Darmon E, Noone D, Veening JW, Westers H, Bron S, Kuipers OP, Devine KM, Hecker M, van Dijl JM.

Mol Microbiol. 2003 Jul;49(1):143-56.

Supplemental Content

Loading ...
Support Center