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Items: 19

1.

High cancer risk and increased mortality in patients with Peutz-Jeghers syndrome.

van Lier MG, Westerman AM, Wagner A, Looman CW, Wilson JH, de Rooij FW, Lemmens VE, Kuipers EJ, Mathus-Vliegen EM, van Leerdam ME.

Gut. 2011 Feb;60(2):141-7. doi: 10.1136/gut.2010.223750.

PMID:
21205875
2.

Multiple anxiogenic drugs recruit a parvalbumin-containing subpopulation of GABAergic interneurons in the basolateral amygdala.

Hale MW, Johnson PL, Westerman AM, Abrams JK, Shekhar A, Lowry CA.

Prog Neuropsychopharmacol Biol Psychiatry. 2010 Oct 1;34(7):1285-93. doi: 10.1016/j.pnpbp.2010.07.012. Epub 2010 Jul 18.

3.

STK11 status and intussusception risk in Peutz-Jeghers syndrome.

Hearle N, Schumacher V, Menko FH, Olschwang S, Boardman LA, Gille JJ, Keller JJ, Westerman AM, Scott RJ, Lim W, Trimbath JD, Giardiello FM, Gruber SB, Offerhaus GJ, Rooij FW, Wilson JH, Hansmann A, Möslein G, Royer-Pokora B, Vogel T, Phillips RK, Spigelman AD, Houlston RS.

J Med Genet. 2006 Aug;43(8):e41.

4.

Nasal polyposis in Peutz-Jeghers syndrome: a distinct histopathological and molecular genetic entity.

de Leng WW, Westerman AM, Weterman MA, Jansen M, van Dekken H, Giardiello FM, de Rooij FW, Paul Wilson JH, Offerhaus GJ, Keller JJ.

J Clin Pathol. 2007 Apr;60(4):392-6. Epub 2006 Jun 14.

5.

Frequency and spectrum of cancers in the Peutz-Jeghers syndrome.

Hearle N, Schumacher V, Menko FH, Olschwang S, Boardman LA, Gille JJ, Keller JJ, Westerman AM, Scott RJ, Lim W, Trimbath JD, Giardiello FM, Gruber SB, Offerhaus GJ, de Rooij FW, Wilson JH, Hansmann A, Möslein G, Royer-Pokora B, Vogel T, Phillips RK, Spigelman AD, Houlston RS.

Clin Cancer Res. 2006 May 15;12(10):3209-15.

6.

LKB1 exonic and whole gene deletions are a common cause of Peutz-Jeghers syndrome.

Volikos E, Robinson J, Aittomäki K, Mecklin JP, Järvinen H, Westerman AM, de Rooji FW, Vogel T, Moeslein G, Launonen V, Tomlinson IP, Silver AR, Aaltonen LA.

J Med Genet. 2006 May;43(5):e18.

7.

Mutation analysis of three genes encoding novel LKB1-interacting proteins, BRG1, STRADalpha, and MO25alpha, in Peutz-Jeghers syndrome.

Alhopuro P, Katajisto P, Lehtonen R, Ylisaukko-Oja SK, Näätsaari L, Karhu A, Westerman AM, Wilson JH, de Rooij FW, Vogel T, Moeslein G, Tomlinson IP, Aaltonen LA, Mäkelä TP, Launonen V.

Br J Cancer. 2005 Mar 28;92(6):1126-9.

8.

Relative frequency and morphology of cancers in STK11 mutation carriers.

Lim W, Olschwang S, Keller JJ, Westerman AM, Menko FH, Boardman LA, Scott RJ, Trimbath J, Giardiello FM, Gruber SB, Gille JJ, Offerhaus GJ, de Rooij FW, Wilson JH, Spigelman AD, Phillips RK, Houlston RS.

Gastroenterology. 2004 Jun;126(7):1788-94.

PMID:
15188174
9.

Cyclooxygenase 2 expression and molecular alterations in Peutz-Jeghers hamartomas and carcinomas.

De Leng WW, Westerman AM, Weterman MA, De Rooij FW, Dekken Hv Hv, De Goeij AF, Gruber SB, Wilson JH, Offerhaus GJ, Giardiello FM, Keller JJ.

Clin Cancer Res. 2003 Aug 1;9(8):3065-72.

10.

Molecular genetic evidence of an association between nasal polyposis and the Peutz-Jeghers syndrome.

Keller JJ, Westerman AM, de Rooij FW, Wilson JH, van Dekken H, Giardiello FM, Weterman MA, Offerhaus GJ.

Ann Intern Med. 2002 Jun 4;136(11):855-6. No abstract available.

PMID:
12044140
11.

Molecular genetic alterations in hamartomatous polyps and carcinomas of patients with Peutz-Jeghers syndrome.

Entius MM, Keller JJ, Westerman AM, van Rees BP, van Velthuysen ML, de Goeij AF, Wilson JH, Giardiello FM, Offerhaus GJ.

J Clin Pathol. 2001 Feb;54(2):126-31.

12.

Peutz-Jeghers syndrome: risks of a hereditary condition.

Westerman AM, Wilson JH.

Scand J Gastroenterol Suppl. 1999;230:64-70. Review.

PMID:
10499464
13.

Novel mutations in the LKB1/STK11 gene in Dutch Peutz-Jeghers families.

Westerman AM, Entius MM, Boor PP, Koole R, de Baar E, Offerhaus GJ, Lubinski J, Lindhout D, Halley DJ, de Rooij FW, Wilson JH.

Hum Mutat. 1999;13(6):476-81.

PMID:
10408777
14.

Molecular and phenotypic markers of hamartomatous polyposis syndromes in the gastrointestinal tract.

Entius MM, Westerman AM, van Velthuysen ML, Wilson JH, Hamilton SR, Giardiello FM, Offerhaus GJ.

Hepatogastroenterology. 1999 Mar-Apr;46(26):661-6. Review.

PMID:
10370593
15.

Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers.

Su GH, Hruban RH, Bansal RK, Bova GS, Tang DJ, Shekher MC, Westerman AM, Entius MM, Goggins M, Yeo CJ, Kern SE.

Am J Pathol. 1999 Jun;154(6):1835-40.

16.

Peutz-Jeghers syndrome: 78-year follow-up of the original family.

Westerman AM, Entius MM, de Baar E, Boor PP, Koole R, van Velthuysen ML, Offerhaus GJ, Lindhout D, de Rooij FW, Wilson JH.

Lancet. 1999 Apr 10;353(9160):1211-5.

PMID:
10217080
17.

Peutz-Jeghers polyps, dysplasia, and K-ras codon 12 mutations.

Entius MM, Westerman AM, Giardiello FM, van Velthuysen ML, Polak MM, Slebos RJ, Wilson JH, Hamilton SR, Offerhaus GJ.

Gut. 1997 Sep;41(3):320-2.

18.

Malignancy in Peutz-Jeghers syndrome? The pitfall of pseudo-invasion.

Westerman AM, van Velthuysen ML, Bac DJ, Schouten WR, Wilson JH.

J Clin Gastroenterol. 1997 Jul;25(1):387-90.

PMID:
9412930
19.

Expression of the multidrug resistance-associated protein (MRP) gene in human cancers.

Nooter K, Westerman AM, Flens MJ, Zaman GJ, Scheper RJ, van Wingerden KE, Burger H, Oostrum R, Boersma T, Sonneveld P, et al.

Clin Cancer Res. 1995 Nov;1(11):1301-10.

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