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EXPRESS: Preserving right ventricular function in patients with pulmonary arterial hypertension: single centre experience with a cardiac magnetic resonance imaging-guided treatment strategy.

Huis In 't Veld AE, Van de Veerdonk MC, Spruijt O, Groeneveldt JA, Marcus JT, Westerhof N, Bogaard HJ, Vonk-Noordegraaf A.

Pulm Circ. 2019 Jan 11:2045894018824553. doi: 10.1177/2045894018824553. [Epub ahead of print] No abstract available.


Uniform tube models with single reflection site do not explain aortic wave travel and pressure wave shape.

Westerhof BE, Westerhof N.

Physiol Meas. 2018 Dec 24;39(12):124006. doi: 10.1088/1361-6579/aaf3dd.


Application of the wave-reservoir approach to different aortic sites: overstretching the concept.

Westerhof N, Westerhof B, Segers P.

J Hypertens. 2018 Apr;36(4):963-964. doi: 10.1097/HJH.0000000000001684. No abstract available.


Commentaries on Viewpoint: Origin of the forward-going "backward" wave.

Hydren JR, Richardson RS, Symons JD, Mynard JP, Smolich JJ, Ramos JS, Dias KA, Dalleck LC, Drummond C, Westerhof B, Westerhof N, Zuo L, Zhou T.

J Appl Physiol (1985). 2017 Nov 1;123(5):1408-1410. doi: 10.1152/japplphysiol.00758.2017. No abstract available.


Treatment strategies for the right heart in pulmonary hypertension.

Westerhof BE, Saouti N, van der Laarse WJ, Westerhof N, Vonk Noordegraaf A.

Cardiovasc Res. 2017 Oct 1;113(12):1465-1473. doi: 10.1093/cvr/cvx148. Review.


Vascular remodelling in the pulmonary circulation after major lung resection.

Rol N, Happé C, Beliën JAM, de Man FS, Westerhof N, Vonk-Noordegraaf A, Grünberg K, Bogaard HJ.

Eur Respir J. 2017 Aug 31;50(2). pii: 1700806. doi: 10.1183/13993003.00806-2017. Print 2017 Aug. No abstract available.


Upfront combination therapy reduces right ventricular volumes in pulmonary arterial hypertension.

van de Veerdonk MC, Huis In T Veld AE, Marcus JT, Westerhof N, Heymans MW, Bogaard HJ, Vonk-Noordegraaf A.

Eur Respir J. 2017 Jun 29;49(6). pii: 1700007. doi: 10.1183/13993003.00007-2017. Print 2017 Jun.


Towards a consensus on the understanding and analysis of the pulse waveform: Results from the 2016 Workshop on Arterial Hemodynamics: Past, present and future.

Segers P, O'Rourke MF, Parker K, Westerhof N, Hughes A.

Artery Res. 2017 Jun;18:75-80. doi: 10.1016/j.artres.2017.03.004. Epub 2017 Apr 28.


Vascular narrowing in pulmonary arterial hypertension is heterogeneous: rethinking resistance.

Rol N, Timmer EM, Faes TJ, Vonk Noordegraaf A, Grünberg K, Bogaard HJ, Westerhof N.

Physiol Rep. 2017 Mar;5(6). pii: e13159. doi: 10.14814/phy2.13159.


Leadership and Innovation-Listening to and Learning From Young People in Burundi.

Nininahazwe C, Alesi J, Caswell G, Lumumba M, Mellin J, Ndayizeye NM, Orza L, Rahimi M, Westerhof N.

J Adolesc Health. 2017 Feb;60(2S2):S7-S9. doi: 10.1016/j.jadohealth.2016.11.012.


Linking Sexual and Reproductive Health and Rights and HIV Services for Young People: The Link Up Project.

Stackpool-Moore L, Bajpai D, Caswell G, Crone T, Dewar F, Gray G, Kyendikuwa A, Mellin J, Miller A, Morgan F, Orza L, Stevenson J, Westerhof N, Wong F, Yam E, Zieman B.

J Adolesc Health. 2017 Feb;60(2S2):S3-S6. doi: 10.1016/j.jadohealth.2016.11.008.


Searching for the Second R in Sexual and Reproductive Health and … Rights.

Orza L, Crone T, Mellin J, Westerhof N, Stackpool-Moore L, Restoy E, Gray G, Stevenson J.

J Adolesc Health. 2017 Feb;60(2S2):S10-S14. doi: 10.1016/j.jadohealth.2016.11.006.


The Relationship Between the Right Ventricle and its Load in Pulmonary Hypertension.

Vonk Noordegraaf A, Westerhof BE, Westerhof N.

J Am Coll Cardiol. 2017 Jan 17;69(2):236-243. doi: 10.1016/j.jacc.2016.10.047. Review.


A critical appraisal of transpulmonary and diastolic pressure gradients.

Handoko ML, De Man FS, Oosterveer FP, Bogaard HJ, Vonk-Noordegraaf A, Westerhof N.

Physiol Rep. 2016 Sep;4(17). pii: e12910. doi: 10.14814/phy2.12910.


Contribution of the Arterial System and the Heart to Blood Pressure during Normal Aging - A Simulation Study.

Maksuti E, Westerhof N, Westerhof BE, Broomé M, Stergiopulos N.

PLoS One. 2016 Jun 24;11(6):e0157493. doi: 10.1371/journal.pone.0157493. eCollection 2016.


Pneumonectomy combined with SU5416 induces severe pulmonary hypertension in rats.

Happé CM, de Raaf MA, Rol N, Schalij I, Vonk-Noordegraaf A, Westerhof N, Voelkel NF, de Man FS, Bogaard HJ.

Am J Physiol Lung Cell Mol Physiol. 2016 Jun 1;310(11):L1088-97. doi: 10.1152/ajplung.00023.2016. Epub 2016 Apr 1.


Intravenous iron therapy in patients with idiopathic pulmonary arterial hypertension and iron deficiency.

Ruiter G, Manders E, Happé CM, Schalij I, Groepenhoff H, Howard LS, Wilkins MR, Bogaard HJ, Westerhof N, van der Laarse WJ, de Man FS, Vonk-Noordegraaf A.

Pulm Circ. 2015 Sep;5(3):466-72. doi: 10.1086/682217.


Wave separation, wave intensity, the reservoir-wave concept, and the instantaneous wave-free ratio: presumptions and principles.

Westerhof N, Segers P, Westerhof BE.

Hypertension. 2015 Sep;66(3):e21. doi: 10.1161/HYP.0000000000000036. No abstract available.


Wave Separation, Wave Intensity, the Reservoir-Wave Concept, and the Instantaneous Wave-Free Ratio: Presumptions and Principles.

Westerhof N, Segers P, Westerhof BE.

Hypertension. 2015 Jul;66(1):93-8. doi: 10.1161/HYPERTENSIONAHA.115.05567. Epub 2015 May 26. Erratum in: Hypertension. 2015 Sep;66(3):e21.


Aortic wave speed: two-point and peripheral pressure methods compared with the gold standard.

Westerhof N, Westerhof BE.

J Hypertens. 2015 May;33(5):926-7. doi: 10.1097/HJH.0000000000000554. No abstract available.


Clinical relevance of right ventricular diastolic stiffness in pulmonary hypertension.

Trip P, Rain S, Handoko ML, van der Bruggen C, Bogaard HJ, Marcus JT, Boonstra A, Westerhof N, Vonk-Noordegraaf A, de Man FS.

Eur Respir J. 2015 Jun;45(6):1603-12. doi: 10.1183/09031936.00156714. Epub 2015 Apr 16.


The effects of exercise on right ventricular contractility and right ventricular-arterial coupling in pulmonary hypertension.

Spruijt OA, de Man FS, Groepenhoff H, Oosterveer F, Westerhof N, Vonk-Noordegraaf A, Bogaard HJ.

Am J Respir Crit Care Med. 2015 May 1;191(9):1050-7. doi: 10.1164/rccm.201412-2271OC.


Predicting pulmonary hypertension with standard computed tomography pulmonary angiography.

Spruijt OA, Bogaard HJ, Heijmans MW, Lely RJ, van de Veerdonk MC, de Man FS, Westerhof N, Vonk-Noordegraaf A.

Int J Cardiovasc Imaging. 2015 Apr;31(4):871-9. doi: 10.1007/s10554-015-0618-x. Epub 2015 Feb 17.


The reservoir wave paradigm discussion.

Westerhof N, Westerhof BE.

J Hypertens. 2015 Mar;33(3):458-60. doi: 10.1097/HJH.0000000000000499. No abstract available.


Bridging cardiovascular physics, physiology, and clinical practice: Karel H. Wesseling, pioneer of continuous noninvasive hemodynamic monitoring.

Westerhof BE, Settels JJ, Bos WJ, Westerhof N, Karemaker JM, Wieling W, van Montfrans GA, van Lieshout JJ.

Am J Physiol Heart Circ Physiol. 2015 Feb 1;308(3):H153-6. doi: 10.1152/ajpheart.00839.2014. Epub 2014 Nov 21. No abstract available.


Signs of right ventricular deterioration in clinically stable patients with pulmonary arterial hypertension.

van de Veerdonk MC, Marcus JT, Westerhof N, de Man FS, Boonstra A, Heymans MW, Bogaard HJ, Vonk Noordegraaf A.

Chest. 2015 Apr;147(4):1063-1071. doi: 10.1378/chest.14-0701.


The arterial load and its role on the heart.

Westerhof N, Westerhof BE.

Hypertension. 2015 Jan;65(1):29-30. doi: 10.1161/HYPERTENSIONAHA.114.04450. Epub 2014 Oct 6. No abstract available.


Contractile dysfunction of left ventricular cardiomyocytes in patients with pulmonary arterial hypertension.

Manders E, Bogaard HJ, Handoko ML, van de Veerdonk MC, Keogh A, Westerhof N, Stienen GJ, Dos Remedios CG, Humbert M, Dorfmüller P, Fadel E, Guignabert C, van der Velden J, Vonk-Noordegraaf A, de Man FS, Ottenheijm CA.

J Am Coll Cardiol. 2014 Jul 8;64(1):28-37. doi: 10.1016/j.jacc.2014.04.031.


Protein changes contributing to right ventricular cardiomyocyte diastolic dysfunction in pulmonary arterial hypertension.

Rain S, Bos Dda S, Handoko ML, Westerhof N, Stienen G, Ottenheijm C, Goebel M, Dorfmüller P, Guignabert C, Humbert M, Bogaard HJ, Remedios CD, Saripalli C, Hidalgo CG, Granzier HL, Vonk-Noordegraaf A, van der Velden J, de Man FS.

J Am Heart Assoc. 2014 Jun 3;3(3):e000716. doi: 10.1161/JAHA.113.000716.


SuHx rat model: partly reversible pulmonary hypertension and progressive intima obstruction.

de Raaf MA, Schalij I, Gomez-Arroyo J, Rol N, Happé C, de Man FS, Vonk-Noordegraaf A, Westerhof N, Voelkel NF, Bogaard HJ.

Eur Respir J. 2014 Jul;44(1):160-8. doi: 10.1183/09031936.00204813. Epub 2014 May 2.


The interventricular septum in pulmonary hypertension does not show features of right ventricular failure.

Ruiter G, van de Veerdonk MC, Bogaard HJ, Wong YY, Marcus JT, Lammertsma AA, Westerhof N, van der Laarse WJ, de Man FS, Vonk-Noordegraaf A.

Int J Cardiol. 2014 May 15;173(3):509-12. doi: 10.1016/j.ijcard.2014.03.064. Epub 2014 Mar 18. No abstract available.


Pulmonary 2-deoxy-2-[(18)F]-fluoro-d-glucose uptake is low in treated patients with idiopathic pulmonary arterial hypertension.

Ruiter G, Wong YY, Raijmakers P, Huisman MC, Lammertsma AA, Knaapen P, de Man FS, Westerhof N, van der Laarse WJ, Vonk-Noordegraaf A.

Pulm Circ. 2013 Sep;3(3):647-53. doi: 10.1086/674335. Epub 2013 Nov 18.


The importance of trabecular hypertrophy in right ventricular adaptation to chronic pressure overload.

van de Veerdonk MC, Dusoswa SA, Marcus JT, Bogaard HJ, Spruijt O, Kind T, Westerhof N, Vonk-Noordegraaf A.

Int J Cardiovasc Imaging. 2014 Feb;30(2):357-65. doi: 10.1007/s10554-013-0338-z. Epub 2013 Dec 4.


Measuring central pulmonary pressures during exercise in COPD: how to cope with respiratory effects.

Boerrigter BG, Waxman AB, Westerhof N, Vonk-Noordegraaf A, Systrom DM.

Eur Respir J. 2014 May;43(5):1316-25. doi: 10.1183/09031936.00016913. Epub 2013 Oct 31.


Right ventricular diastolic impairment in patients with pulmonary arterial hypertension.

Rain S, Handoko ML, Trip P, Gan CT, Westerhof N, Stienen GJ, Paulus WJ, Ottenheijm CA, Marcus JT, Dorfmüller P, Guignabert C, Humbert M, Macdonald P, Dos Remedios C, Postmus PE, Saripalli C, Hidalgo CG, Granzier HL, Vonk-Noordegraaf A, van der Velden J, de Man FS.

Circulation. 2013 Oct 29;128(18):2016-25, 1-10. doi: 10.1161/CIRCULATIONAHA.113.001873. Epub 2013 Sep 20.


Prognostic relevance of changes in exercise test variables in pulmonary arterial hypertension.

Groepenhoff H, Vonk-Noordegraaf A, van de Veerdonk MC, Boonstra A, Westerhof N, Bogaard HJ.

PLoS One. 2013 Sep 5;8(9):e72013. doi: 10.1371/journal.pone.0072013. eCollection 2013.


Severely reduced diffusion capacity in idiopathic pulmonary arterial hypertension: patient characteristics and treatment responses.

Trip P, Nossent EJ, de Man FS, van den Berk IA, Boonstra A, Groepenhoff H, Leter EM, Westerhof N, Grünberg K, Bogaard HJ, Vonk-Noordegraaf A.

Eur Respir J. 2013 Dec;42(6):1575-85. doi: 10.1183/09031936.00184412. Epub 2013 Aug 15.


Reversibility of the monocrotaline pulmonary hypertension rat model.

Ruiter G, de Man FS, Schalij I, Sairras S, Grünberg K, Westerhof N, van der Laarse WJ, Vonk-Noordegraaf A.

Eur Respir J. 2013 Aug;42(2):553-6. doi: 10.1183/09031936.00012313. No abstract available.


A review of methods to determine the functional arterial parameters stiffness and resistance.

Westerhof N, Westerhof BE.

J Hypertens. 2013 Sep;31(9):1769-75. doi: 10.1097/HJH.0b013e3283633589. Review.


CrossTalk proposal: Forward and backward pressure waves in the arterial system do represent reality.

Westerhof N, Westerhof BE.

J Physiol. 2013 Mar 1;591(5):1167-9; discussion 1177. doi: 10.1113/jphysiol.2012.249763. No abstract available.


Describing right ventricular function.

Vonk-Noordegraaf A, Westerhof N.

Eur Respir J. 2013 Jun;41(6):1419-23. doi: 10.1183/09031936.00160712. Epub 2013 Jan 11. Review.


Accurate assessment of load-independent right ventricular systolic function in patients with pulmonary hypertension.

Trip P, Kind T, van de Veerdonk MC, Marcus JT, de Man FS, Westerhof N, Vonk-Noordegraaf A.

J Heart Lung Transplant. 2013 Jan;32(1):50-5. doi: 10.1016/j.healun.2012.09.022. Epub 2012 Nov 17.


Right ventricular oxygen supply parameters are decreased in human and experimental pulmonary hypertension.

Ruiter G, Ying Wong Y, de Man FS, Louis Handoko M, Jaspers RT, Postmus PE, Westerhof N, Niessen HW, van der Laarse WJ, Vonk-Noordegraaf A.

J Heart Lung Transplant. 2013 Feb;32(2):231-40. doi: 10.1016/j.healun.2012.09.025. Epub 2012 Nov 9.


Diaphragm weakness in pulmonary arterial hypertension: role of sarcomeric dysfunction.

Manders E, de Man FS, Handoko ML, Westerhof N, van Hees HW, Stienen GJ, Vonk-Noordegraaf A, Ottenheijm CA.

Am J Physiol Lung Cell Mol Physiol. 2012 Dec 15;303(12):L1070-8. doi: 10.1152/ajplung.00135.2012. Epub 2012 Sep 7.


Aortic function quantified: the heart's essential cushion.

Saouti N, Marcus JT, Vonk Noordegraaf A, Westerhof N.

J Appl Physiol (1985). 2012 Oct 15;113(8):1285-91. doi: 10.1152/japplphysiol.00432.2012. Epub 2012 Aug 30.


Ventilatory and cardiocirculatory exercise profiles in COPD: the role of pulmonary hypertension.

Boerrigter BG, Bogaard HJ, Trip P, Groepenhoff H, Rietema H, Holverda S, Boonstra A, Postmus PE, Westerhof N, Vonk-Noordegraaf A.

Chest. 2012 Nov;142(5):1166-1174. doi: 10.1378/chest.11-2798.


Magnitude and return time of the reflected wave: the effects of large artery stiffness and aortic geometry.

Westerhof BE, Westerhof N.

J Hypertens. 2012 May;30(5):932-9. doi: 10.1097/HJH.0b013e3283524932.


Right atrial pressure affects the interaction between lung mechanics and right ventricular function in spontaneously breathing COPD patients.

Boerrigter B, Trip P, Bogaard HJ, Groepenhoff H, Oosterveer F, Westerhof N, Vonk Noordegraaf A.

PLoS One. 2012;7(1):e30208. doi: 10.1371/journal.pone.0030208. Epub 2012 Jan 17.


Pulmonary endarterectomy normalizes interventricular dyssynchrony and right ventricular systolic wall stress.

Mauritz GJ, Vonk-Noordegraaf A, Kind T, Surie S, Kloek JJ, Bresser P, Saouti N, Bosboom J, Westerhof N, Marcus JT.

J Cardiovasc Magn Reson. 2012 Jan 12;14:5. doi: 10.1186/1532-429X-14-5.


Bisoprolol delays progression towards right heart failure in experimental pulmonary hypertension.

de Man FS, Handoko ML, van Ballegoij JJ, Schalij I, Bogaards SJ, Postmus PE, van der Velden J, Westerhof N, Paulus WJ, Vonk-Noordegraaf A.

Circ Heart Fail. 2012 Jan;5(1):97-105. doi: 10.1161/CIRCHEARTFAILURE.111.964494. Epub 2011 Dec 9.


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