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Items: 18

1.

Identification of hyper-rewired genomic stress non-oncogene addiction genes across 15 cancer types.

Hjaltelin JX, Izarzugaza JMG, Jensen LJ, Russo F, Westergaard D, Brunak S.

NPJ Syst Biol Appl. 2019 Aug 7;5:27. doi: 10.1038/s41540-019-0104-5. eCollection 2019.

2.

Herpes Simplex Virus Type 1 infection is associated with suicidal behavior and first registered psychiatric diagnosis in a healthy population.

Nissen J, Trabjerg B, Pedersen MG, Banasik K, Pedersen OB, Sørensen E, Nielsen KR, Erikstrup C, Petersen MS, Paarup HM, Bruun-Rasmussen P, Westergaard D, Hansen TF, Pedersen CB, Werge T, Torrey F, Hjalgrim H, Mortensen PB, Yolken R, Brunak S, Ullum H, Burgdorf KS.

Psychoneuroendocrinology. 2019 Oct;108:150-154. doi: 10.1016/j.psyneuen.2019.06.015. Epub 2019 Jun 28.

3.

DBDS Genomic Cohort, a prospective and comprehensive resource for integrative and temporal analysis of genetic, environmental and lifestyle factors affecting health of blood donors.

Hansen TF, Banasik K, Erikstrup C, Pedersen OB, Westergaard D, Chmura PJ, Nielsen K, Thørner L, Hjalgrim H, Paarup H, Larsen MAH, Petersen M, Jennum P, Andersen S, Nyegaard M, Jemec GBE, Olesen J, Werge T, Johansson PI, Sørensen E, Brunak S, Ullum H, Burgdorf KS.

BMJ Open. 2019 Jun 9;9(6):e028401. doi: 10.1136/bmjopen-2018-028401.

4.

Comorbidity landscape of the Danish patient population affected by chromosome abnormalities.

Jørgensen IF, Russo F, Jensen AB, Westergaard D, Lademann M, Hu JX, Brunak S, Belling K.

Genet Med. 2019 Apr 25. doi: 10.1038/s41436-019-0519-9. [Epub ahead of print]

PMID:
31019277
5.

Population-wide analysis of differences in disease progression patterns in men and women.

Westergaard D, Moseley P, Sørup FKH, Baldi P, Brunak S.

Nat Commun. 2019 Feb 8;10(1):666. doi: 10.1038/s41467-019-08475-9.

6.

Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders.

Burgdorf KS, Trabjerg BB, Pedersen MG, Nissen J, Banasik K, Pedersen OB, Sørensen E, Nielsen KR, Larsen MH, Erikstrup C, Bruun-Rasmussen P, Westergaard D, Thørner LW, Hjalgrim H, Paarup HM, Brunak S, Pedersen CB, Torrey EF, Werge T, Mortensen PB, Yolken RH, Ullum H.

Brain Behav Immun. 2019 Jul;79:152-158. doi: 10.1016/j.bbi.2019.01.026. Epub 2019 Jan 29.

7.

Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers.

Tsafou K, Katschnig AM, Radic-Sarikas B, Mutz CN, Iljin K, Schwentner R, Kauer MO, Mühlbacher K, Aryee DNT, Westergaard D, Haapa-Paananen S, Fey V, Superti-Furga G, Toretsky J, Brunak S, Kovar H.

Oncotarget. 2018 Jul 24;9(57):31018-31031. doi: 10.18632/oncotarget.25760. eCollection 2018 Jul 24.

8.

Unexplored therapeutic opportunities in the human genome.

Oprea TI, Bologa CG, Brunak S, Campbell A, Gan GN, Gaulton A, Gomez SM, Guha R, Hersey A, Holmes J, Jadhav A, Jensen LJ, Johnson GL, Karlson A, Leach AR, Ma'ayan A, Malovannaya A, Mani S, Mathias SL, McManus MT, Meehan TF, von Mering C, Muthas D, Nguyen DT, Overington JP, Papadatos G, Qin J, Reich C, Roth BL, Schürer SC, Simeonov A, Sklar LA, Southall N, Tomita S, Tudose I, Ursu O, Vidovic D, Waller A, Westergaard D, Yang JJ, Zahoránszky-Köhalmi G.

Nat Rev Drug Discov. 2018 May;17(5):377. doi: 10.1038/nrd.2018.52. Epub 2018 Mar 23.

PMID:
29567993
9.

Unexplored therapeutic opportunities in the human genome.

Oprea TI, Bologa CG, Brunak S, Campbell A, Gan GN, Gaulton A, Gomez SM, Guha R, Hersey A, Holmes J, Jadhav A, Jensen LJ, Johnson GL, Karlson A, Leach AR, Ma'ayan A, Malovannaya A, Mani S, Mathias SL, McManus MT, Meehan TF, von Mering C, Muthas D, Nguyen DT, Overington JP, Papadatos G, Qin J, Reich C, Roth BL, Schürer SC, Simeonov A, Sklar LA, Southall N, Tomita S, Tudose I, Ursu O, Vidovic D, Waller A, Westergaard D, Yang JJ, Zahoránszky-Köhalmi G.

Nat Rev Drug Discov. 2018 May;17(5):317-332. doi: 10.1038/nrd.2018.14. Epub 2018 Mar 23. Review. Erratum in: Nat Rev Drug Discov. 2018 Mar 23;:.

10.

A comprehensive and quantitative comparison of text-mining in 15 million full-text articles versus their corresponding abstracts.

Westergaard D, Stærfeldt HH, Tønsberg C, Jensen LJ, Brunak S.

PLoS Comput Biol. 2018 Feb 15;14(2):e1005962. doi: 10.1371/journal.pcbi.1005962. eCollection 2018 Feb.

11.

Sequencing and de novo assembly of 150 genomes from Denmark as a population reference.

Maretty L, Jensen JM, Petersen B, Sibbesen JA, Liu S, Villesen P, Skov L, Belling K, Theil Have C, Izarzugaza JMG, Grosjean M, Bork-Jensen J, Grove J, Als TD, Huang S, Chang Y, Xu R, Ye W, Rao J, Guo X, Sun J, Cao H, Ye C, van Beusekom J, Espeseth T, Flindt E, Friborg RM, Halager AE, Le Hellard S, Hultman CM, Lescai F, Li S, Lund O, Løngren P, Mailund T, Matey-Hernandez ML, Mors O, Pedersen CNS, Sicheritz-Pontén T, Sullivan P, Syed A, Westergaard D, Yadav R, Li N, Xu X, Hansen T, Krogh A, Bolund L, Sørensen TIA, Pedersen O, Gupta R, Rasmussen S, Besenbacher S, Børglum AD, Wang J, Eiberg H, Kristiansen K, Brunak S, Schierup MH.

Nature. 2017 Aug 3;548(7665):87-91. doi: 10.1038/nature23264. Epub 2017 Jul 26.

PMID:
28746312
12.

Klinefelter syndrome comorbidities linked to increased X chromosome gene dosage and altered protein interactome activity.

Belling K, Russo F, Jensen AB, Dalgaard MD, Westergaard D, Rajpert-De Meyts E, Skakkebæk NE, Juul A, Brunak S.

Hum Mol Genet. 2017 Apr 1;26(7):1219-1229. doi: 10.1093/hmg/ddx014.

13.

TEMPORAL ORDER OF DISEASE PAIRS AFFECTS SUBSEQUENT DISEASE TRAJECTORIES: THE CASE OF DIABETES AND SLEEP APNEA.

Beck MK, Westergaard D, Jensen AB, Groop L, Brunak S.

Pac Symp Biocomput. 2017;22:380-389. doi: 10.1142/9789813207813_0036.

14.

Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios.

Besenbacher S, Liu S, Izarzugaza JM, Grove J, Belling K, Bork-Jensen J, Huang S, Als TD, Li S, Yadav R, Rubio-García A, Lescai F, Demontis D, Rao J, Ye W, Mailund T, Friborg RM, Pedersen CN, Xu R, Sun J, Liu H, Wang O, Cheng X, Flores D, Rydza E, Rapacki K, Damm Sørensen J, Chmura P, Westergaard D, Dworzynski P, Sørensen TI, Lund O, Hansen T, Xu X, Li N, Bolund L, Pedersen O, Eiberg H, Krogh A, Børglum AD, Brunak S, Kristiansen K, Schierup MH, Wang J, Gupta R, Villesen P, Rasmussen S.

Nat Commun. 2015 Jan 19;6:5969. doi: 10.1038/ncomms6969.

15.

Acquisition of docetaxel resistance in breast cancer cells reveals upregulation of ABCB1 expression as a key mediator of resistance accompanied by discrete upregulation of other specific genes and pathways.

Hansen SN, Westergaard D, Thomsen MB, Vistesen M, Do KN, Fogh L, Belling KC, Wang J, Yang H, Gupta R, Ditzel HJ, Moreira J, Brünner N, Stenvang J, Schrohl AS.

Tumour Biol. 2015 Jun;36(6):4327-38. doi: 10.1007/s13277-015-3072-4. Epub 2015 Jan 18.

PMID:
25596703
16.

The transcriptome of corona radiata cells from individual MІІ oocytes that after ICSI developed to embryos selected for transfer: PCOS women compared to healthy women.

Wissing ML, Sonne SB, Westergaard D, Nguyen Kd, Belling K, Høst T, Mikkelsen AL.

J Ovarian Res. 2014 Nov 29;7:110. doi: 10.1186/s13048-014-0110-6.

17.

Exploring mechanisms of diet-colon cancer associations through candidate molecular interaction networks.

Westergaard D, Li J, Jensen K, Kouskoumvekaki I, Panagiotou G.

BMC Genomics. 2014 May 17;15:380. doi: 10.1186/1471-2164-15-380.

18.

[Indications and use of fissure sealants in public dental health care in Denmark. A questionnaire-investigation].

Ekstrand K, Nielsen LA, Westergaard D, Reinert M, Thylstrup A.

Tandlaegebladet. 1991 Nov;95(16):741-7. Danish.

PMID:
1816647

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