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Items: 36

1.

A Novel Polar Core and Weakly Fixed C-Tail in Squid Arrestin Provide New Insight into Interaction with Rhodopsin.

Bandyopadhyay A, Van Eps N, Eger BT, Rauscher S, Yedidi RS, Moroni T, West GM, Robinson KA, Griffin PR, Mitchell J, Ernst OP.

J Mol Biol. 2018 Oct 19;430(21):4102-4118. doi: 10.1016/j.jmb.2018.08.009. Epub 2018 Aug 16.

PMID:
30120952
2.

Delineating the role of cooperativity in the design of potent PROTACs for BTK.

Zorba A, Nguyen C, Xu Y, Starr J, Borzilleri K, Smith J, Zhu H, Farley KA, Ding W, Schiemer J, Feng X, Chang JS, Uccello DP, Young JA, Garcia-Irrizary CN, Czabaniuk L, Schuff B, Oliver R, Montgomery J, Hayward MM, Coe J, Chen J, Niosi M, Luthra S, Shah JC, El-Kattan A, Qiu X, West GM, Noe MC, Shanmugasundaram V, Gilbert AM, Brown MF, Calabrese MF.

Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):E7285-E7292. doi: 10.1073/pnas.1803662115. Epub 2018 Jul 16.

3.

Sites associated with Kalydeco binding on human Cystic Fibrosis Transmembrane Conductance Regulator revealed by Hydrogen/Deuterium Exchange.

Byrnes LJ, Xu Y, Qiu X, Hall JD, West GM.

Sci Rep. 2018 Mar 16;8(1):4664. doi: 10.1038/s41598-018-22959-6.

4.

Biophysical Interactions of Direct AMPK Activators.

Kurumbail RG, West GM, Dharmarajan V, Borzilleri KA, Withka JM, Ward J, Reyes AR, Rajamohan F, Griffin PR, Calabrese MF.

Methods Mol Biol. 2018;1732:29-55. doi: 10.1007/978-1-4939-7598-3_3.

PMID:
29480467
5.

Emerging Methods in Chemoproteomics with Relevance to Drug Discovery.

Nguyen C, West GM, Geoghegan KF.

Methods Mol Biol. 2017;1513:11-22. Review.

PMID:
27807827
6.

Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitors.

Zuhl AM, Nolan CE, Brodney MA, Niessen S, Atchison K, Houle C, Karanian DA, Ambroise C, Brulet JW, Beck EM, Doran SD, O'Neill BT, Am Ende CW, Chang C, Geoghegan KF, West GM, Judkins JC, Hou X, Riddell DR, Johnson DS.

Nat Commun. 2016 Oct 11;7:13042. doi: 10.1038/ncomms13042.

7.

SERBP1 Is a Component of the Liver Receptor Homologue-1 Transcriptional Complex.

Mari Y, West GM, Scharager-Tapia C, Pascal BD, Garcia-Ordonez RD, Griffin PR.

J Proteome Res. 2015 Nov 6;14(11):4571-80. doi: 10.1021/acs.jproteome.5b00379. Epub 2015 Oct 7.

8.

Software Analysis of Uncorrelated MS1 Peaks for Discovery of Post-Translational Modifications.

Pascal BD, West GM, Scharager-Tapia C, Flefil R, Moroni T, Martinez-Acedo P, Griffin PR, Carvalloza AC.

J Am Soc Mass Spectrom. 2015 Dec;26(12):2133-40. doi: 10.1007/s13361-015-1229-4. Epub 2015 Aug 12.

PMID:
26265041
9.

Conformational states of the full-length glucagon receptor.

Yang L, Yang D, de Graaf C, Moeller A, West GM, Dharmarajan V, Wang C, Siu FY, Song G, Reedtz-Runge S, Pascal BD, Wu B, Potter CS, Zhou H, Griffin PR, Carragher B, Yang H, Wang MW, Stevens RC, Jiang H.

Nat Commun. 2015 Jul 31;6:7859. doi: 10.1038/ncomms8859.

10.

Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser.

Kang Y, Zhou XE, Gao X, He Y, Liu W, Ishchenko A, Barty A, White TA, Yefanov O, Han GW, Xu Q, de Waal PW, Ke J, Tan MH, Zhang C, Moeller A, West GM, Pascal BD, Van Eps N, Caro LN, Vishnivetskiy SA, Lee RJ, Suino-Powell KM, Gu X, Pal K, Ma J, Zhi X, Boutet S, Williams GJ, Messerschmidt M, Gati C, Zatsepin NA, Wang D, James D, Basu S, Roy-Chowdhury S, Conrad CE, Coe J, Liu H, Lisova S, Kupitz C, Grotjohann I, Fromme R, Jiang Y, Tan M, Yang H, Li J, Wang M, Zheng Z, Li D, Howe N, Zhao Y, Standfuss J, Diederichs K, Dong Y, Potter CS, Carragher B, Caffrey M, Jiang H, Chapman HN, Spence JC, Fromme P, Weierstall U, Ernst OP, Katritch V, Gurevich VV, Griffin PR, Hubbell WL, Stevens RC, Cherezov V, Melcher K, Xu HE.

Nature. 2015 Jul 30;523(7562):561-7. doi: 10.1038/nature14656. Epub 2015 Jul 22.

11.

Global analysis of protein folding thermodynamics for disease state characterization.

Adhikari J, West GM, Fitzgerald MC.

J Proteome Res. 2015 May 1;14(5):2287-97. doi: 10.1021/acs.jproteome.5b00057. Epub 2015 Apr 9.

12.

Antiproliferation activity of a small molecule repressor of liver receptor homolog 1.

Corzo CA, Mari Y, Chang MR, Khan T, Kuruvilla D, Nuhant P, Kumar N, West GM, Duckett DR, Roush WR, Griffin PR.

Mol Pharmacol. 2015 Feb;87(2):296-304. doi: 10.1124/mol.114.095554. Epub 2014 Dec 3.

13.

Mass spectrometry approach and ELISA reveal the effect of codon optimization on N-linked glycosylation of HIV-1 gp120.

Honarmand Ebrahimi K, West GM, Flefil R.

J Proteome Res. 2014 Dec 5;13(12):5801-11. doi: 10.1021/pr500740n. Epub 2014 Oct 6.

14.

Glucagon-like peptide-1 receptor ligand interactions: structural cross talk between ligands and the extracellular domain.

West GM, Willard FS, Sloop KW, Showalter AD, Pascal BD, Griffin PR.

PLoS One. 2014 Sep 2;9(9):e105683. doi: 10.1371/journal.pone.0105683. eCollection 2014.

15.

Using unnatural amino acid mutagenesis to probe the regulation of PRMT1.

Rust HL, Subramanian V, West GM, Young DD, Schultz PG, Thompson PR.

ACS Chem Biol. 2014 Mar 21;9(3):649-55. doi: 10.1021/cb400859z. Epub 2014 Jan 6.

16.

Protein conformation ensembles monitored by HDX reveal a structural rationale for abscisic acid signaling protein affinities and activities.

West GM, Pascal BD, Ng LM, Soon FF, Melcher K, Xu HE, Chalmers MJ, Griffin PR.

Structure. 2013 Feb 5;21(2):229-35. doi: 10.1016/j.str.2012.12.001. Epub 2013 Jan 3.

17.

Thermodynamic analysis of protein-ligand binding interactions in complex biological mixtures using the stability of proteins from rates of oxidation.

Strickland EC, Geer MA, Tran DT, Adhikari J, West GM, DeArmond PD, Xu Y, Fitzgerald MC.

Nat Protoc. 2013 Jan;8(1):148-61. doi: 10.1038/nprot.2012.146. Epub 2012 Dec 20.

18.

HDX workbench: software for the analysis of H/D exchange MS data.

Pascal BD, Willis S, Lauer JL, Landgraf RR, West GM, Marciano D, Novick S, Goswami D, Chalmers MJ, Griffin PR.

J Am Soc Mass Spectrom. 2012 Sep;23(9):1512-21. doi: 10.1007/s13361-012-0419-6. Epub 2012 Jun 13.

19.

Structural basis for basal activity and autoactivation of abscisic acid (ABA) signaling SnRK2 kinases.

Ng LM, Soon FF, Zhou XE, West GM, Kovach A, Suino-Powell KM, Chalmers MJ, Li J, Yong EL, Zhu JK, Griffin PR, Melcher K, Xu HE.

Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21259-64. doi: 10.1073/pnas.1118651109. Epub 2011 Dec 12.

20.

Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases.

Soon FF, Ng LM, Zhou XE, West GM, Kovach A, Tan MH, Suino-Powell KM, He Y, Xu Y, Chalmers MJ, Brunzelle JS, Zhang H, Yang H, Jiang H, Li J, Yong EL, Cutler S, Zhu JK, Griffin PR, Melcher K, Xu HE.

Science. 2012 Jan 6;335(6064):85-8. doi: 10.1126/science.1215106. Epub 2011 Nov 24.

21.

Ligand-dependent perturbation of the conformational ensemble for the GPCR β2 adrenergic receptor revealed by HDX.

West GM, Chien EY, Katritch V, Gatchalian J, Chalmers MJ, Stevens RC, Griffin PR.

Structure. 2011 Oct 12;19(10):1424-32. doi: 10.1016/j.str.2011.08.001. Epub 2011 Sep 1.

22.

Stable isotope labeling strategy for protein-ligand binding analysis in multi-component protein mixtures.

DeArmond PD, West GM, Huang HT, Fitzgerald MC.

J Am Soc Mass Spectrom. 2011 Mar;22(3):418-30. doi: 10.1007/s13361-010-0060-1. Epub 2011 Feb 1.

23.

Differential hydrogen/deuterium exchange mass spectrometry analysis of protein-ligand interactions.

Chalmers MJ, Busby SA, Pascal BD, West GM, Griffin PR.

Expert Rev Proteomics. 2011 Feb;8(1):43-59. doi: 10.1586/epr.10.109. Review.

24.

Discovery of novel cyclophilin A ligands using an H/D exchange- and mass spectrometry-based strategy.

Dearmond PD, West GM, Anbalagan V, Campa MJ, Patz EF Jr, Fitzgerald MC.

J Biomol Screen. 2010 Oct;15(9):1051-62. doi: 10.1177/1087057110382775. Epub 2010 Sep 20.

25.

Mass spectrometry-based thermal shift assay for protein-ligand binding analysis.

West GM, Thompson JW, Soderblom EJ, Dubois LG, Dearmond PD, Moseley MA, Fitzgerald MC.

Anal Chem. 2010 Jul 1;82(13):5573-81. doi: 10.1021/ac100465a.

PMID:
20527820
26.

Quantitative proteomics approach for identifying protein-drug interactions in complex mixtures using protein stability measurements.

West GM, Tucker CL, Xu T, Park SK, Han X, Yates JR 3rd, Fitzgerald MC.

Proc Natl Acad Sci U S A. 2010 May 18;107(20):9078-82. doi: 10.1073/pnas.1000148107. Epub 2010 May 3.

27.

Painting proteins with covalent labels: what's in the picture?

Fitzgerald MC, West GM.

J Am Soc Mass Spectrom. 2009 Jun;20(6):1193-206. doi: 10.1016/j.jasms.2009.02.006. Epub 2009 Feb 12.

28.

Thermodynamic analysis of protein stability and ligand binding using a chemical modification- and mass spectrometry-based strategy.

West GM, Tang L, Fitzgerald MC.

Anal Chem. 2008 Jun 1;80(11):4175-85. doi: 10.1021/ac702610a. Epub 2008 May 6.

PMID:
18457414
29.

Reliability and repeatability of 3-D body scanner (LASS) measurements compared to anthropometry.

Brooke-Wavell K, Jones PR, West GM.

Ann Hum Biol. 1994 Nov-Dec;21(6):571-7.

PMID:
7840496
30.

The Loughborough anthropometric shadow scanner (LASS).

Jones PR, West GM, Harris DH, Read JB.

Endeavour. 1989;13(4):162-8.

PMID:
2482808
31.

Hepatic delta-aminolaevulinic acid synthetase in an attack of hereditary coproporphyria and during remission.

McIntyre N, Pearson AJ, Allan DJ, Craske S, West GM, Moore MR, Beattie AD, Paxton J, Goldberg A.

Lancet. 1971 Mar 20;1(7699):560-4. No abstract available.

PMID:
4100900
32.

Roasting meat at 250 degrees F.

STECH OD, WEST GM.

J Am Diet Assoc. 1954 Feb;30(2):160. No abstract available.

PMID:
13128999
33.
34.

WORCESTER SCHOOL CHILDREN.-THE GROWTH OF THE BODY, HEAD, AND FACE.

West GM.

Science. 1893 Jan 6;21(518):2-4. No abstract available.

PMID:
17821689
35.

The Question of the Artificial Production of Variations in Type.

West GM.

Science. 1892 Apr 22;19(481):236. No abstract available.

PMID:
17754953
36.

Growth of the Face.

West GM.

Science. 1891 Jul 3;18(439):10-1. No abstract available.

PMID:
17757772

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