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Items: 44


Complement and T Cell Metabolism: Food for Thought.

West EE, Kemper C.

Immunometabolism. 2019 Jun 20;1(T Cell Metabolic Reprogramming):e190006. doi: 10.20900/immunometab20190006.


IL-21/type I interferon interplay regulates neutrophil-dependent innate immune responses to Staphylococcus aureus.

Spolski R, West EE, Li P, Veenbergen S, Yung S, Kazemian M, Oh J, Yu ZX, Freeman AF, Holland SM, Murphy PM, Leonard WJ.

Elife. 2019 Apr 16;8. pii: e45501. doi: 10.7554/eLife.45501.


Asparaginyl Endopeptidase (Legumain) Supports Human Th1 Induction via Cathepsin L-Mediated Intracellular C3 Activation.

Freeley S, Cardone J, Günther SC, West EE, Reinheckel T, Watts C, Kemper C, Kolev MV.

Front Immunol. 2018 Oct 24;9:2449. doi: 10.3389/fimmu.2018.02449. eCollection 2018.


Complement receptor CD46 co-stimulates optimal human CD8+ T cell effector function via fatty acid metabolism.

Arbore G, West EE, Rahman J, Le Friec G, Niyonzima N, Pirooznia M, Tunc I, Pavlidis P, Powell N, Li Y, Liu P, Servais A, Couzi L, Fremeaux-Bacchi V, Placais L, Ferraro A, Walsh PR, Kavanagh D, Afzali B, Lavender P, Lachmann HJ, Kemper C.

Nat Commun. 2018 Oct 10;9(1):4186. doi: 10.1038/s41467-018-06706-z.


Unexpected Roles for Intracellular Complement in the Regulation of Th1 Responses.

West EE, Afzali B, Kemper C.

Adv Immunol. 2018;138:35-70. doi: 10.1016/ Epub 2018 Mar 26. Review.


Complement and the Regulation of T Cell Responses.

West EE, Kolev M, Kemper C.

Annu Rev Immunol. 2018 Apr 26;36:309-338. doi: 10.1146/annurev-immunol-042617-053245. Review.


Effector CD8 T cells dedifferentiate into long-lived memory cells.

Youngblood B, Hale JS, Kissick HT, Ahn E, Xu X, Wieland A, Araki K, West EE, Ghoneim HE, Fan Y, Dogra P, Davis CW, Konieczny BT, Antia R, Cheng X, Ahmed R.

Nature. 2017 Dec 21;552(7685):404-409. doi: 10.1038/nature25144. Epub 2017 Dec 13.


STAT5-mediated chromatin interactions in superenhancers activate IL-2 highly inducible genes: Functional dissection of the Il2ra gene locus.

Li P, Mitra S, Spolski R, Oh J, Liao W, Tang Z, Mo F, Li X, West EE, Gromer D, Lin JX, Liu C, Ruan Y, Leonard WJ.

Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):12111-12119. doi: 10.1073/pnas.1714019114. Epub 2017 Oct 24.


A TSLP-complement axis mediates neutrophil killing of methicillin-resistant Staphylococcus aureus.

West EE, Spolski R, Kazemian M, Yu ZX, Kemper C, Leonard WJ.

Sci Immunol. 2016 Nov 18;1(5). pii: eaaf8471. doi: 10.1126/sciimmunol.aaf8471.


T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⁺ T cells.

Arbore G, West EE, Spolski R, Robertson AAB, Klos A, Rheinheimer C, Dutow P, Woodruff TM, Yu ZX, O'Neill LA, Coll RC, Sher A, Leonard WJ, Köhl J, Monk P, Cooper MA, Arno M, Afzali B, Lachmann HJ, Cope AP, Mayer-Barber KD, Kemper C.

Science. 2016 Jun 17;352(6292):aad1210. doi: 10.1126/science.aad1210.


EGR2 is critical for peripheral naïve T-cell differentiation and the T-cell response to influenza.

Du N, Kwon H, Li P, West EE, Oh J, Liao W, Yu Z, Ren M, Leonard WJ.

Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16484-9. doi: 10.1073/pnas.1417215111. Epub 2014 Nov 3.


Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection.

Penaloza-MacMaster P, Kamphorst AO, Wieland A, Araki K, Iyer SS, West EE, O'Mara L, Yang S, Konieczny BT, Sharpe AH, Freeman GJ, Rudensky AY, Ahmed R.

J Exp Med. 2014 Aug 25;211(9):1905-18. doi: 10.1084/jem.20132577. Epub 2014 Aug 11.


Thymic stromal lymphopoietin and interleukin-4 mediate the pathogenesis of halothane-induced liver injury in mice.

Proctor WR, Chakraborty M, Fullerton AM, Korrapati MC, Ryan PM, Semple K, Morrison JC, Berkson JD, Chea LS, Yang Q, Li AP, Spolski R, West EE, Rochman Y, Leonard WJ, Bourdi M, Pohl LR.

Hepatology. 2014 Nov;60(5):1741-52. doi: 10.1002/hep.27169. Epub 2014 May 20.


Opposing actions of IL-2 and IL-21 on Th9 differentiation correlate with their differential regulation of BCL6 expression.

Liao W, Spolski R, Li P, Du N, West EE, Ren M, Mitra S, Leonard WJ.

Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3508-13. doi: 10.1073/pnas.1301138111. Epub 2014 Feb 18.


TSLP: A Key Regulator of Asthma Pathogenesis.

West EE, Kashyap M, Leonard WJ.

Drug Discov Today Dis Mech. 2012 Dec 1;9(3-4). doi: 10.1016/j.ddmec.2012.09.003.


PD-L1 blockade synergizes with IL-2 therapy in reinvigorating exhausted T cells.

West EE, Jin HT, Rasheed AU, Penaloza-Macmaster P, Ha SJ, Tan WG, Youngblood B, Freeman GJ, Smith KA, Ahmed R.

J Clin Invest. 2013 Jun;123(6):2604-15. doi: 10.1172/JCI67008. Epub 2013 May 15.


The cytokines IL-21 and GM-CSF have opposing regulatory roles in the apoptosis of conventional dendritic cells.

Wan CK, Oh J, Li P, West EE, Wong EA, Andraski AB, Spolski R, Yu ZX, He J, Kelsall BL, Leonard WJ.

Immunity. 2013 Mar 21;38(3):514-27. doi: 10.1016/j.immuni.2013.02.011. Epub 2013 Feb 28.


Comparative analysis of simian immunodeficiency virus gag-specific effector and memory CD8+ T cells induced by different adenovirus vectors.

Tan WG, Jin HT, West EE, Penaloza-MacMaster P, Wieland A, Zilliox MJ, McElrath MJ, Barouch DH, Ahmed R.

J Virol. 2013 Feb;87(3):1359-72. doi: 10.1128/JVI.02055-12. Epub 2012 Nov 21.


Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8(+) T cells.

Youngblood B, Oestreich KJ, Ha SJ, Duraiswamy J, Akondy RS, West EE, Wei Z, Lu P, Austin JW, Riley JL, Boss JM, Ahmed R.

Immunity. 2011 Sep 23;35(3):400-12. doi: 10.1016/j.immuni.2011.06.015.


Tight regulation of memory CD8(+) T cells limits their effectiveness during sustained high viral load.

West EE, Youngblood B, Tan WG, Jin HT, Araki K, Alexe G, Konieczny BT, Calpe S, Freeman GJ, Terhorst C, Haining WN, Ahmed R.

Immunity. 2011 Aug 26;35(2):285-98. doi: 10.1016/j.immuni.2011.05.017.


Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection.

Jin HT, Anderson AC, Tan WG, West EE, Ha SJ, Araki K, Freeman GJ, Kuchroo VK, Ahmed R.

Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14733-8. doi: 10.1073/pnas.1009731107. Epub 2010 Aug 2.


PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice.

Mueller SN, Vanguri VK, Ha SJ, West EE, Keir ME, Glickman JN, Sharpe AH, Ahmed R.

J Clin Invest. 2010 Jul;120(7):2508-15. doi: 10.1172/JCI40040. Epub 2010 Jun 14.


CD154 deficiency uncouples allograft CD8+ T-cell effector function from proliferation and inhibits murine airway obliteration.

Shah PD, West EE, Whitlock AB, Orens JB, McDyer JF.

Am J Transplant. 2009 Dec;9(12):2697-706. doi: 10.1111/j.1600-6143.2009.02805.x.


CD4+CD25+Foxp3+ Tregs resolve experimental lung injury in mice and are present in humans with acute lung injury.

D'Alessio FR, Tsushima K, Aggarwal NR, West EE, Willett MH, Britos MF, Pipeling MR, Brower RG, Tuder RM, McDyer JF, King LS.

J Clin Invest. 2009 Oct;119(10):2898-913. doi: 10.1172/JCI36498. Epub 2009 Sep 21.


T cell responses to mycobacterial catalase-peroxidase profile a pathogenic antigen in systemic sarcoidosis.

Chen ES, Wahlström J, Song Z, Willett MH, Wikén M, Yung RC, West EE, McDyer JF, Zhang Y, Eklund A, Grunewald J, Moller DR.

J Immunol. 2008 Dec 15;181(12):8784-96.


Manipulating both the inhibitory and stimulatory immune system towards the success of therapeutic vaccination against chronic viral infections.

Ha SJ, West EE, Araki K, Smith KA, Ahmed R.

Immunol Rev. 2008 Jun;223:317-33. doi: 10.1111/j.1600-065X.2008.00638.x. Review.


Differential CMV-specific CD8+ effector T cell responses in the lung allograft predominate over the blood during human primary infection.

Pipeling MR, West EE, Osborne CM, Whitlock AB, Dropulic LK, Willett MH, Forman M, Valsamakis A, Orens JB, Moller DR, Lechtzin N, Migueles SA, Connors M, McDyer JF.

J Immunol. 2008 Jul 1;181(1):546-56.


Persistent cytomegalovirus-specific memory responses in the lung allograft and blood following primary infection in lung transplant recipients.

Shlobin OA, West EE, Lechtzin N, Miller SM, Borja M, Orens JB, Dropulic LK, McDyer JF.

J Immunol. 2006 Feb 15;176(4):2625-34.


Pluripotent allospecific CD8+ effector T cells traffic to lung in murine obliterative airway disease.

West EE, Lavoie TL, Orens JB, Chen ES, Ye SQ, Finkelman FD, Garcia JG, McDyer JF.

Am J Respir Cell Mol Biol. 2006 Jan;34(1):108-18. Epub 2005 Sep 29.


Heritability of nociception. III. Genetic relationships among commonly used assays of nociception and hypersensitivity.

Lariviere WR, Wilson SG, Laughlin TM, Kokayeff A, West EE, Adhikari SM, Wan Y, Mogil JS.

Pain. 2002 May;97(1-2):75-86.


Identification of quantitative trait loci for chemical/inflammatory nociception in mice.

Wilson SG, Chesler EJ, Hain H, Rankin AJ, Schwarz JZ, Call SB, Murray MR, West EE, Teuscher C, Rodriguez-Zas S, Belknap JK, Mogil JS.

Pain. 2002 Apr;96(3):385-91.


Quantitation of maxillary remodeling. 1. A description of osseous changes relative to superimposition on metallic implants.

Baumrind S, Korn EL, Ben-Bassat Y, West EE.

Am J Orthod Dentofacial Orthop. 1987 Jan;91(1):29-41.


Prediction of mandibular rotation: an empirical test of clinician performance.

Baumrind S, Korn EL, West EE.

Am J Orthod. 1984 Nov;86(5):371-85.


Superimpositional assessment of treatment-associated changes in the temporomandibular joint and the mandibular symphysis.

Baumrind S, Korn EL, Isaacson RJ, West EE, Molthen R.

Am J Orthod. 1983 Dec;84(6):443-65.


Quantitative analysis of the orthodontic and orthopedic effects of maxillary traction.

Baumrind S, Korn EL, Isaacson RJ, West EE, Molthen R.

Am J Orthod. 1983 Nov;84(5):384-98.


Changes in facial dimensions associated with the use of forces to retract the maxilla.

Baumrind S, Korn EL, Molthen R, West EE.

Am J Orthod. 1981 Jul;80(1):17-30. No abstract available.


Distal displacement of the maxilla and the upper first molar.

Baumrind S, Molthen R, West EE, Miller DM.

Am J Orthod. 1979 Jun;75(6):630-40.


Mandibular plan changes during maxillary retraction. Part 2. Addenda.

Baumrind S, Molthen R, West EE, Miller DM.

Am J Orthod. 1979 Jan;75(1):86-9. No abstract available.


Mandibular plane changes during maxillary retraction. Part 2.

Baumrind S, Molthen R, West EE, Miller DM.

Am J Orthod. 1978 Dec;74(6):603-20. No abstract available.


Mandibular plane changes during maxillary retraction.

Baumrind S, Molthen R, West EE, Miller DM.

Am J Orthod. 1978 Jul;74(1):32-40. No abstract available.


Treatment objectives in the deciduous dentition.

West EE.

Am J Orthod. 1969 Jun;55(6):617-32. No abstract available.


Diastema--a cause for concern.

West EE.

Dent Clin North Am. 1968 Jul:425-34. No abstract available.


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