Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 82

1.
2.

Hematologic toxicity in BRCA1 and BRCA2 mutation carriers during chemotherapy: A retrospective matched cohort study.

West AH, Knollman H, Dugan J, Hedeker D, Handorf EA, Nielsen SM, Bealin LC, Goldblatt LG, Willems H, Daly MB, Afghahi A, Olopade OI, Hulick PJ, Shagisultanova E, Huo D, Obeid E, Churpek JE.

Cancer Med. 2019 Sep;8(12):5609-5618. doi: 10.1002/cam4.2471. Epub 2019 Aug 12.

3.

Role of the highly conserved G68 residue in the yeast phosphorelay protein Ypd1: implications for interactions between histidine phosphotransfer (HPt) and response regulator proteins.

Kennedy EN, Hebdon SD, Menon SK, Foster CA, Copeland DM, Xu Q, Janiak-Spens F, West AH.

BMC Biochem. 2019 Jan 21;20(1):1. doi: 10.1186/s12858-019-0104-5.

4.

Regulatory Targets of the Response Regulator RR_1586 from Clostridioides difficile Identified Using a Bacterial One-Hybrid Screen.

Hebdon SD, Menon SK, Richter-Addo GB, Karr EA, West AH.

J Bacteriol. 2018 Nov 6;200(23). pii: e00351-18. doi: 10.1128/JB.00351-18. Print 2018 Dec 1.

5.

Clinical interpretation of pathogenic ATM and CHEK2 variants on multigene panel tests: navigating moderate risk.

West AH, Blazer KR, Stoll J, Jones M, Weipert CM, Nielsen SM, Kupfer SS, Weitzel JN, Olopade OI.

Fam Cancer. 2018 Oct;17(4):495-505. doi: 10.1007/s10689-018-0070-x.

6.

Prognostic tumor sequencing panels frequently identify germ line variants associated with hereditary hematopoietic malignancies.

Drazer MW, Kadri S, Sukhanova M, Patil SA, West AH, Feurstein S, Calderon DA, Jones MF, Weipert CM, Daugherty CK, Ceballos-López AA, Raca G, Lingen MW, Li Z, Segal JP, Churpek JE, Godley LA.

Blood Adv. 2018 Jan 23;2(2):146-150. doi: 10.1182/bloodadvances.2017013037.

7.

Old and new tools in the clinical diagnosis of inherited bone marrow failure syndromes.

West AH, Churpek JE.

Hematology Am Soc Hematol Educ Program. 2017 Dec 8;2017(1):79-87. doi: 10.1182/asheducation-2017.1.79. Review.

8.
9.

Crystal structures of two nitroreductases from hypervirulent Clostridium difficile and functionally related interactions with the antibiotic metronidazole.

Wang B, Powell SM, Hessami N, Najar FZ, Thomas LM, Karr EA, West AH, Richter-Addo GB.

Nitric Oxide. 2016 Nov 30;60:32-39. doi: 10.1016/j.niox.2016.09.003. Epub 2016 Sep 10.

10.

Crystal structure and DNA binding activity of a PadR family transcription regulator from hypervirulent Clostridium difficile R20291.

Isom CE, Menon SK, Thomas LM, West AH, Richter-Addo GB, Karr EA.

BMC Microbiol. 2016 Oct 4;16(1):231.

11.

Metal Transition in Sodium-Ammonia Nanodroplets.

Hartweg S, West AH, Yoder BL, Signorell R.

Angew Chem Int Ed Engl. 2016 Sep 26;55(40):12347-50. doi: 10.1002/anie.201604282. Epub 2016 Aug 29.

PMID:
27571535
12.
13.

Solvated Electrons in Clusters: Magic Numbers for the Photoelectron Anisotropy.

West AH, Yoder BL, Luckhaus D, Signorell R.

J Phys Chem A. 2015 Dec 17;119(50):12376-82. doi: 10.1021/acs.jpca.5b07629. Epub 2015 Sep 18.

PMID:
26355269
14.

Probing the chemical mechanism of saccharopine reductase from Saccharomyces cerevisiae using site-directed mutagenesis.

Vashishtha AK, West AH, Cook PF.

Arch Biochem Biophys. 2015 Oct 15;584:98-106. doi: 10.1016/j.abb.2015.08.023. Epub 2015 Sep 3.

15.
16.

Angle-Resolved Photoemission of Solvated Electrons in Sodium-Doped Clusters.

West AH, Yoder BL, Luckhaus D, Saak CM, Doppelbauer M, Signorell R.

J Phys Chem Lett. 2015 Apr 16;6(8):1487-92. doi: 10.1021/acs.jpclett.5b00477. Epub 2015 Apr 7.

PMID:
26263156
17.

Electron mean free path from angle-dependent photoelectron spectroscopy of aerosol particles.

Goldmann M, Miguel-Sánchez J, West AH, Yoder BL, Signorell R.

J Chem Phys. 2015 Jun 14;142(22):224304. doi: 10.1063/1.4922307.

PMID:
26071707
18.

Barrierless proton transfer across weak CH⋯O hydrogen bonds in dimethyl ether dimer.

Yoder BL, Bravaya KB, Bodi A, West AH, Sztáray B, Signorell R.

J Chem Phys. 2015 Mar 21;142(11):114303. doi: 10.1063/1.4914456.

PMID:
25796245
19.

Unique metastases of ALK mutated lung cancer activated to the adnexa of the uterus.

West AH, Yamada SD, MacMahon H, Acharya SS, Ali SM, He J, Lukas RV, Miller VA, Salgia R.

Case Rep Clin Pathol. 2014 Sep;1(2):151-154.

20.

Familial myelodysplastic syndrome/acute leukemia syndromes: a review and utility for translational investigations.

West AH, Godley LA, Churpek JE.

Ann N Y Acad Sci. 2014 Mar;1310:111-8. doi: 10.1111/nyas.12346. Epub 2014 Jan 27. Review.

21.

Size-dependent velocity map photoelectron imaging of nanosized ammonia aerosol particles.

West AH, Yoder BL, Signorell R.

J Phys Chem A. 2013 Dec 19;117(50):13326-35. doi: 10.1021/jp406313a. Epub 2013 Aug 14.

PMID:
23919276
22.

Histidine phosphotransfer proteins in fungal two-component signal transduction pathways.

Fassler JS, West AH.

Eukaryot Cell. 2013 Aug;12(8):1052-60. doi: 10.1128/EC.00083-13. Epub 2013 Jun 14. Review.

23.

A velocity map imaging photoelectron spectrometer for the study of ultrafine aerosols with a table-top VUV laser and Na-doping for particle sizing applied to dimethyl ether condensation.

Yoder BL, West AH, Schläppi B, Chasovskikh E, Signorell R.

J Chem Phys. 2013 Jan 28;138(4):044202. doi: 10.1063/1.4788620.

PMID:
23387577
24.

Immunodominance of antigenic site B over site A of hemagglutinin of recent H3N2 influenza viruses.

Popova L, Smith K, West AH, Wilson PC, James JA, Thompson LF, Air GM.

PLoS One. 2012;7(7):e41895. doi: 10.1371/journal.pone.0041895. Epub 2012 Jul 25.

25.

Supporting role of lysine 13 and glutamate 16 in the acid-base mechanism of saccharopine dehydrogenase from Saccharomyces cerevisiae.

Kumar VP, West AH, Cook PF.

Arch Biochem Biophys. 2012 Jun 1;522(1):57-61. doi: 10.1016/j.abb.2012.03.027. Epub 2012 Apr 11.

PMID:
22521736
26.

Evidence in support of lysine 77 and histidine 96 as acid-base catalytic residues in saccharopine dehydrogenase from Saccharomyces cerevisiae.

Kumar VP, Thomas LM, Bobyk KD, Andi B, Cook PF, West AH.

Biochemistry. 2012 Jan 31;51(4):857-66. doi: 10.1021/bi201808. Epub 2012 Jan 23.

27.

Contribution of K99 and D319 to substrate binding and catalysis in the saccharopine dehydrogenase reaction.

Ekanayake DK, West AH, Cook PF.

Arch Biochem Biophys. 2011 Oct;514(1-2):8-15. doi: 10.1016/j.abb.2011.07.013. Epub 2011 Jul 27.

28.

The oxidation state of active site thiols determines activity of saccharopine dehydrogenase at low pH.

Bobyk KD, Kim SG, Kumar VP, Kim SK, West AH, Cook PF.

Arch Biochem Biophys. 2011 Sep 15;513(2):71-80. doi: 10.1016/j.abb.2011.07.009. Epub 2011 Jul 28.

PMID:
21798231
29.

Kinetic and chemical mechanisms of homocitrate synthase from Thermus thermophilus.

Kumar VP, West AH, Cook PF.

J Biol Chem. 2011 Aug 19;286(33):29428-39. doi: 10.1074/jbc.M111.246355. Epub 2011 Jul 6.

30.

Fungal Skn7 stress responses and their relationship to virulence.

Fassler JS, West AH.

Eukaryot Cell. 2011 Feb;10(2):156-67. doi: 10.1128/EC.00245-10. Epub 2010 Dec 3. Review.

31.

Genetic and biochemical analysis of the SLN1 pathway in Saccharomyces cerevisiae.

Fassler JS, West AH.

Methods Enzymol. 2010;471:291-317. doi: 10.1016/S0076-6879(10)71016-8. Epub 2010 Mar 1.

32.

Kinetic studies of the yeast His-Asp phosphorelay signaling pathway.

Kaserer AO, Andi B, Cook PF, West AH.

Methods Enzymol. 2010;471:59-75. doi: 10.1016/S0076-6879(10)71004-1. Epub 2010 Mar 1.

33.

Glutamates 78 and 122 in the active site of saccharopine dehydrogenase contribute to reactant binding and modulate the basicity of the acid-base catalysts.

Ekanayake DK, Andi B, Bobyk KD, West AH, Cook PF.

J Biol Chem. 2010 Jul 2;285(27):20756-68. doi: 10.1074/jbc.M110.119826. Epub 2010 Apr 28.

34.

Effects of osmolytes on the SLN1-YPD1-SSK1 phosphorelay system from Saccharomyces cerevisiae.

Kaserer AO, Andi B, Cook PF, West AH.

Biochemistry. 2009 Aug 25;48(33):8044-50. doi: 10.1021/bi900886g.

35.
36.

Chemical mechanism of saccharopine reductase from Saccharomyces cerevisiae.

Vashishtha AK, West AH, Cook PF.

Biochemistry. 2009 Jun 30;48(25):5899-907. doi: 10.1021/bi900599s.

PMID:
19449898
37.

Potassium is an activator of homoisocitrate dehydrogenase from Saccharomyces cerevisiae.

Lin Y, West AH, Cook PF.

Biochemistry. 2008 Oct 7;47(40):10809-15. doi: 10.1021/bi801370h. Epub 2008 Sep 12.

38.

Evidence for a catalytic dyad in the active site of homocitrate synthase from Saccharomyces cerevisiae.

Qian J, Khandogin J, West AH, Cook PF.

Biochemistry. 2008 Jul 1;47(26):6851-8. doi: 10.1021/bi800087k. Epub 2008 Jun 6.

PMID:
18533686
39.

Overall kinetic mechanism of saccharopine dehydrogenase (L-glutamate forming) from Saccharomyces cerevisiae.

Vashishtha AK, West AH, Cook PF.

Biochemistry. 2008 May 13;47(19):5417-23. doi: 10.1021/bi800086g. Epub 2008 Apr 17.

PMID:
18416559
40.

Chemical mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae.

Lin Y, Volkman J, Nicholas KM, Yamamoto T, Eguchi T, Nimmo SL, West AH, Cook PF.

Biochemistry. 2008 Apr 1;47(13):4169-80. doi: 10.1021/bi702361j. Epub 2008 Mar 6.

PMID:
18321070
41.

Assessment of four biodiesel production processes using HYSYS.Plant.

West AH, Posarac D, Ellis N.

Bioresour Technol. 2008 Sep;99(14):6587-601. doi: 10.1016/j.biortech.2007.11.046. Epub 2008 Jan 29.

PMID:
18234493
42.
43.

Crystal structures of ligand-bound saccharopine dehydrogenase from Saccharomyces cerevisiae.

Andi B, Xu H, Cook PF, West AH.

Biochemistry. 2007 Nov 6;46(44):12512-21. Epub 2007 Oct 16.

PMID:
17939687
44.

Crystal structures of manganese- and cobalt-substituted myoglobin in complex with NO and nitrite reveal unusual ligand conformations.

Zahran ZN, Chooback L, Copeland DM, West AH, Richter-Addo GB.

J Inorg Biochem. 2008 Feb;102(2):216-33. Epub 2007 Aug 25.

45.

Functional characterization of the phosphorelay protein Mpr1p from Schizosaccharomyces pombe.

Tan H, Janiak-Spens F, West AH.

FEMS Yeast Res. 2007 Sep;7(6):912-21. Epub 2007 Jun 7.

46.

Determinants of substrate specificity for saccharopine dehydrogenase from Saccharomyces cerevisiae.

Xu H, West AH, Cook PF.

Biochemistry. 2007 Jun 26;46(25):7625-36. Epub 2007 Jun 2.

47.

Complete kinetic mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae.

Lin Y, Alguindigue SS, Volkman J, Nicholas KM, West AH, Cook PF.

Biochemistry. 2007 Jan 23;46(3):890-8.

48.

A proposed proton shuttle mechanism for saccharopine dehydrogenase from Saccharomyces cerevisiae.

Xu H, Alguindigue SS, West AH, Cook PF.

Biochemistry. 2007 Jan 23;46(3):871-82.

49.

Functional studies of the Ssk1p response regulator protein of Candida albicans as determined by phenotypic analysis of receiver domain point mutants.

Menon V, Li D, Chauhan N, Rajnarayanan R, Dubrovska A, West AH, Calderone R.

Mol Microbiol. 2006 Nov;62(4):997-1013. Epub 2006 Oct 13.

50.

Overall kinetic mechanism of saccharopine dehydrogenase from Saccharomyces cerevisiae.

Xu H, West AH, Cook PF.

Biochemistry. 2006 Oct 3;45(39):12156-66.

PMID:
17002315

Supplemental Content

Support Center