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Items: 31

1.

A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma.

Salaverria I, Martin-Guerrero I, Wagener R, Kreuz M, Kohler CW, Richter J, Pienkowska-Grela B, Adam P, Burkhardt B, Claviez A, Damm-Welk C, Drexler HG, Hummel M, Jaffe ES, Küppers R, Lefebvre C, Lisfeld J, Löffler M, Macleod RA, Nagel I, Oschlies I, Rosolowski M, Russell RB, Rymkiewicz G, Schindler D, Schlesner M, Scholtysik R, Schwaenen C, Spang R, Szczepanowski M, Trümper L, Vater I, Wessendorf S, Klapper W, Siebert R; Molecular Mechanisms in Malignant Lymphoma Network Project; Berlin-Frankfurt-Münster Non-Hodgkin Lymphoma Group.

Blood. 2014 Feb 20;123(8):1187-98. doi: 10.1182/blood-2013-06-507996. Epub 2014 Jan 7.

2.

Biological characterization of adult MYC-translocation-positive mature B-cell lymphomas other than molecular Burkitt lymphoma.

Aukema SM, Kreuz M, Kohler CW, Rosolowski M, Hasenclever D, Hummel M, Küppers R, Lenze D, Ott G, Pott C, Richter J, Rosenwald A, Szczepanowski M, Schwaenen C, Stein H, Trautmann H, Wessendorf S, Trümper L, Loeffler M, Spang R, Kluin PM, Klapper W, Siebert R; Molecular Mechanisms in Malignant Lymphomas Network Project.

Haematologica. 2014 Apr;99(4):726-35. doi: 10.3324/haematol.2013.091827. Epub 2013 Oct 31.

3.

High resolution copy number analysis of IRF4 translocation-positive diffuse large B-cell and follicular lymphomas.

Salaverria I, Martin-Guerrero I, Burkhardt B, Kreuz M, Zenz T, Oschlies I, Arnold N, Baudis M, Bens S, García-Orad A, Lisfeld J, Schwaenen C, Szczepanowski M, Wessendorf S, Pfreundschuh M, Trümper L, Klapper W, Siebert R.

Genes Chromosomes Cancer. 2013 Feb;52(2):150-5. doi: 10.1002/gcc.22014. Epub 2012 Oct 17.

PMID:
23073988
4.

Patient age at diagnosis is associated with the molecular characteristics of diffuse large B-cell lymphoma.

Klapper W, Kreuz M, Kohler CW, Burkhardt B, Szczepanowski M, Salaverria I, Hummel M, Loeffler M, Pellissery S, Woessmann W, Schwänen C, Trümper L, Wessendorf S, Spang R, Hasenclever D, Siebert R; Molecular Mechanisms in Malignant Lymphomas Network Project of the Deutsche Krebshilfe.

Blood. 2012 Feb 23;119(8):1882-7. doi: 10.1182/blood-2011-10-388470. Epub 2012 Jan 11.

5.

Recurrent deletions of the TNFSF7 and TNFSF9 genes in 19p13.3 in diffuse large B-cell and Burkitt lymphomas.

Scholtysik R, Nagel I, Kreuz M, Vater I, Giefing M, Schwaenen C, Wessendorf S, Trümper L, Loeffler M, Siebert R, Küppers R.

Int J Cancer. 2012 Sep 1;131(5):E830-5. doi: 10.1002/ijc.27416. Epub 2012 Jan 31.

6.

Identification of genomic alterations associated with metastasis and cancer specific survival in clear cell renal cell carcinoma.

Sanjmyatav J, Junker K, Matthes S, Muehr M, Sava D, Sternal M, Wessendorf S, Kreuz M, Gajda M, Wunderlich H, Schwaenen C.

J Urol. 2011 Nov;186(5):2078-83. doi: 10.1016/j.juro.2011.06.050. Epub 2011 Sep 23.

PMID:
21944119
7.

Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults.

Salaverria I, Philipp C, Oschlies I, Kohler CW, Kreuz M, Szczepanowski M, Burkhardt B, Trautmann H, Gesk S, Andrusiewicz M, Berger H, Fey M, Harder L, Hasenclever D, Hummel M, Loeffler M, Mahn F, Martin-Guerrero I, Pellissery S, Pott C, Pfreundschuh M, Reiter A, Richter J, Rosolowski M, Schwaenen C, Stein H, Trümper L, Wessendorf S, Spang R, Küppers R, Klapper W, Siebert R; Molecular Mechanisms in Malignant Lymphomas Network Project of the Deutsche Krebshilfe; German High-Grade Lymphoma Study Group; Berlin-Frankfurt-Münster-NHL trial group.

Blood. 2011 Jul 7;118(1):139-47. doi: 10.1182/blood-2011-01-330795. Epub 2011 Apr 12.

8.

Detection of genomic aberrations in molecularly defined Burkitt's lymphoma by array-based, high resolution, single nucleotide polymorphism analysis.

Scholtysik R, Kreuz M, Klapper W, Burkhardt B, Feller AC, Hummel M, Loeffler M, Rosolowski M, Schwaenen C, Spang R, Stein H, Thorns C, Trümper L, Vater I, Wessendorf S, Zenz T, Siebert R, Küppers R; Molecular Mechanisms in Malignant Lymphomas Network Project of Deutsche Krebshilfe.

Haematologica. 2010 Dec;95(12):2047-55. doi: 10.3324/haematol.2010.026831. Epub 2010 Sep 7.

9.

Micronuclei in peripheral blood from patients after cytostatic therapy mainly arise ex vivo from persistent damage.

Arsoy NS, Neuss S, Wessendorf S, Bommer M, Viardot A, Schütz P, Speit G.

Mutagenesis. 2009 Jul;24(4):351-7. doi: 10.1093/mutage/gep015. Epub 2009 May 7.

PMID:
19423564
10.

New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling.

Martín-Subero JI, Kreuz M, Bibikova M, Bentink S, Ammerpohl O, Wickham-Garcia E, Rosolowski M, Richter J, Lopez-Serra L, Ballestar E, Berger H, Agirre X, Bernd HW, Calvanese V, Cogliatti SB, Drexler HG, Fan JB, Fraga MF, Hansmann ML, Hummel M, Klapper W, Korn B, Küppers R, Macleod RA, Möller P, Ott G, Pott C, Prosper F, Rosenwald A, Schwaenen C, Schübeler D, Seifert M, Stürzenhofecker B, Weber M, Wessendorf S, Loeffler M, Trümper L, Stein H, Spang R, Esteller M, Barker D, Hasenclever D, Siebert R; Molecular Mechanisms in Malignant Lymphomas Network Project of the Deutsche Krebshilfe.

Blood. 2009 Mar 12;113(11):2488-97. doi: 10.1182/blood-2008-04-152900. Epub 2008 Dec 15.

11.

A distinctive subtype of t(14;18)-negative nodal follicular non-Hodgkin lymphoma characterized by a predominantly diffuse growth pattern and deletions in the chromosomal region 1p36.

Katzenberger T, Kalla J, Leich E, Stöcklein H, Hartmann E, Barnickel S, Wessendorf S, Ott MM, Müller-Hermelink HK, Rosenwald A, Ott G.

Blood. 2009 Jan 29;113(5):1053-61. doi: 10.1182/blood-2008-07-168682. Epub 2008 Oct 31.

12.

Microarray-based genomic profiling reveals novel genomic aberrations in follicular lymphoma which associate with patient survival and gene expression status.

Schwaenen C, Viardot A, Berger H, Barth TF, Bentink S, Döhner H, Enz M, Feller AC, Hansmann ML, Hummel M, Kestler HA, Klapper W, Kreuz M, Lenze D, Loeffler M, Möller P, Müller-Hermelink HK, Ott G, Rosolowski M, Rosenwald A, Ruf S, Siebert R, Spang R, Stein H, Truemper L, Lichter P, Bentz M, Wessendorf S; Molecular Mechanisms in Malignant Lymphomas Network Project of the Deutsche Krebshilfe.

Genes Chromosomes Cancer. 2009 Jan;48(1):39-54. doi: 10.1002/gcc.20617.

PMID:
18828156
13.

Pathway activation patterns in diffuse large B-cell lymphomas.

Bentink S, Wessendorf S, Schwaenen C, Rosolowski M, Klapper W, Rosenwald A, Ott G, Banham AH, Berger H, Feller AC, Hansmann ML, Hasenclever D, Hummel M, Lenze D, Möller P, Stuerzenhofecker B, Loeffler M, Truemper L, Stein H, Siebert R, Spang R; Molecular Mechanisms in Malignant Lymphomas Network Project of the.

Leukemia. 2008 Sep;22(9):1746-54. doi: 10.1038/leu.2008.166. Epub 2008 Jun 26.

PMID:
18580954
14.

Molecular profiling of pediatric mature B-cell lymphoma treated in population-based prospective clinical trials.

Klapper W, Szczepanowski M, Burkhardt B, Berger H, Rosolowski M, Bentink S, Schwaenen C, Wessendorf S, Spang R, Möller P, Hansmann ML, Bernd HW, Ott G, Hummel M, Stein H, Loeffler M, Trümper L, Zimmermann M, Reiter A, Siebert R; Molecular Mechanisms in Malignant Lymphomas Network Project of the Deutsche Krebshilfe.

Blood. 2008 Aug 15;112(4):1374-81. doi: 10.1182/blood-2008-01-136465. Epub 2008 May 28.

15.

Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma.

Dierlamm J, Murga Penas EM, Bentink S, Wessendorf S, Berger H, Hummel M, Klapper W, Lenze D, Rosenwald A, Haralambieva E, Ott G, Cogliatti SB, Möller P, Schwaenen C, Stein H, Löffler M, Spang R, Trümper L, Siebert R; Deutsche Krebshilfe Network Project "Molecular Mechanisms in Malignant Lymphomas".

Haematologica. 2008 May;93(5):688-96. doi: 10.3324/haematol.12057. Epub 2008 Mar 26.

16.

Detailed mapping of chromosome 17p deletions reveals HIC1 as a novel tumor suppressor gene candidate telomeric to TP53 in diffuse large B-cell lymphoma.

Stöcklein H, Smardova J, Macak J, Katzenberger T, Höller S, Wessendorf S, Hutter G, Dreyling M, Haralambieva E, Mäder U, Müller-Hermelink HK, Rosenwald A, Ott G, Kalla J.

Oncogene. 2008 Apr 17;27(18):2613-25. Epub 2007 Nov 5.

PMID:
17982487
17.

Development and implementation of an analysis tool for array-based comparative genomic hybridization.

Kreuz M, Rosolowski M, Berger H, Schwaenen C, Wessendorf S, Loeffler M, Hasenclever D.

Methods Inf Med. 2007;46(5):608-13.

PMID:
17938787
18.

Further delineation of chromosomal consensus regions in primary mediastinal B-cell lymphomas: an analysis of 37 tumor samples using high-resolution genomic profiling (array-CGH).

Wessendorf S, Barth TF, Viardot A, Mueller A, Kestler HA, Kohlhammer H, Lichter P, Bentz M, Döhner H, Möller P, Schwaenen C.

Leukemia. 2007 Dec;21(12):2463-9. Epub 2007 Aug 30.

PMID:
17728785
19.

[A new dimension of DNA analysis: genomic profiling by matrix CGH].

Joos S, Radlwimmer B, Nessling M, Fritz B, Schwaenen C, Wessendorf S, Bentz M, Lichter P.

Verh Dtsch Ges Pathol. 2003;87:165-71. German.

PMID:
16888909
20.

Disclosure of candidate genes in acute myeloid leukemia with complex karyotypes using microarray-based molecular characterization.

Rücker FG, Bullinger L, Schwaenen C, Lipka DB, Wessendorf S, Fröhling S, Bentz M, Miller S, Scholl C, Schlenk RF, Radlwimmer B, Kestler HA, Pollack JR, Lichter P, Döhner K, Döhner H.

J Clin Oncol. 2006 Aug 20;24(24):3887-94. Epub 2006 Jul 24.

PMID:
16864856
21.

A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling.

Hummel M, Bentink S, Berger H, Klapper W, Wessendorf S, Barth TF, Bernd HW, Cogliatti SB, Dierlamm J, Feller AC, Hansmann ML, Haralambieva E, Harder L, Hasenclever D, Kühn M, Lenze D, Lichter P, Martin-Subero JI, Möller P, Müller-Hermelink HK, Ott G, Parwaresch RM, Pott C, Rosenwald A, Rosolowski M, Schwaenen C, Stürzenhofecker B, Szczepanowski M, Trautmann H, Wacker HH, Spang R, Loeffler M, Trümper L, Stein H, Siebert R; Molecular Mechanisms in Malignant Lymphomas Network Project of the Deutsche Krebshilfe.

N Engl J Med. 2006 Jun 8;354(23):2419-30.

22.

Candidate genes in breast cancer revealed by microarray-based comparative genomic hybridization of archived tissue.

Nessling M, Richter K, Schwaenen C, Roerig P, Wrobel G, Wessendorf S, Fritz B, Bentz M, Sinn HP, Radlwimmer B, Lichter P.

Cancer Res. 2005 Jan 15;65(2):439-47.

23.

Genomic DNA-chip hybridization reveals a higher incidence of genomic amplifications in pancreatic cancer than conventional comparative genomic hybridization and leads to the identification of novel candidate genes.

Holzmann K, Kohlhammer H, Schwaenen C, Wessendorf S, Kestler HA, Schwoerer A, Rau B, Radlwimmer B, Döhner H, Lichter P, Gress T, Bentz M.

Cancer Res. 2004 Jul 1;64(13):4428-33. Erratum in: Cancer Res. 2004 Sep 1;64(17):6358.

24.

Genomic DNA-chip hybridization in t(11;14)-positive mantle cell lymphomas shows a high frequency of aberrations and allows a refined characterization of consensus regions.

Kohlhammer H, Schwaenen C, Wessendorf S, Holzmann K, Kestler HA, Kienle D, Barth TF, Möller P, Ott G, Kalla J, Radlwimmer B, Pscherer A, Stilgenbauer S, Döhner H, Lichter P, Bentz M.

Blood. 2004 Aug 1;104(3):795-801. Epub 2004 Apr 13.

25.

Automated array-based genomic profiling in chronic lymphocytic leukemia: development of a clinical tool and discovery of recurrent genomic alterations.

Schwaenen C, Nessling M, Wessendorf S, Salvi T, Wrobel G, Radlwimmer B, Kestler HA, Haslinger C, Stilgenbauer S, Döhner H, Bentz M, Lichter P.

Proc Natl Acad Sci U S A. 2004 Jan 27;101(4):1039-44. Epub 2004 Jan 16.

26.

DNA microarray analysis in malignant lymphomas.

Schwaenen C, Wessendorf S, Kestler HA, Döhner H, Lichter P, Bentz M.

Ann Hematol. 2003 Jun;82(6):323-32. Epub 2003 Apr 26. Review.

PMID:
12719886
27.

Hidden gene amplifications in aggressive B-cell non-Hodgkin lymphomas detected by microarray-based comparative genomic hybridization.

Wessendorf S, Schwaenen C, Kohlhammer H, Kienle D, Wrobel G, Barth TF, Nessling M, Möller P, Döhner H, Lichter P, Bentz M.

Oncogene. 2003 Mar 6;22(9):1425-9.

PMID:
12618769
28.

Microarray-based copy number and expression profiling in dedifferentiated and pleomorphic liposarcoma.

Fritz B, Schubert F, Wrobel G, Schwaenen C, Wessendorf S, Nessling M, Korz C, Rieker RJ, Montgomery K, Kucherlapati R, Mechtersheimer G, Eils R, Joos S, Lichter P.

Cancer Res. 2002 Jun 1;62(11):2993-8.

29.

Early bursting strength of human colon anastomoses--an in vitro study comparing current anastomotic techniques.

Schwab R, Wessendorf S, Gutcke A, Becker P.

Langenbecks Arch Surg. 2002 Jan;386(7):507-11. Epub 2001 Nov 1.

PMID:
11819108
30.

Automated screening for genomic imbalances using matrix-based comparative genomic hybridization.

Wessendorf S, Fritz B, Wrobel G, Nessling M, Lampel S, Göettel D, Küepper M, Joos S, Hopman T, Kokocinski F, Döhner H, Bentz M, Schwäenen C, Lichter P.

Lab Invest. 2002 Jan;82(1):47-60.

PMID:
11796825
31.

Potential of chromosomal and matrix-based comparative genomic hybridization for molecular diagnostics in lymphomas.

Wessendorf S, Lichter P, Schwänen C, Fritz B, Baudis M, Walenta K, Kloess M, Döhner H, Bentz M.

Ann Hematol. 2001;80 Suppl 3:B35-7. Review. No abstract available.

PMID:
11757703

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