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Items: 1 to 50 of 101

1.

Reciprocal signaling and direct physical interactions between fibroblasts and breast cancer cells in a 3D environment.

Wessels DJ, Pradhan N, Park YN, Klepitsch MA, Lusche DF, Daniels KJ, Conway KD, Voss ER, Hegde SV, Conway TP, Soll DR.

PLoS One. 2019 Jun 24;14(6):e0218854. doi: 10.1371/journal.pone.0218854. eCollection 2019.

2.

Integrin α-3 ß-1's central role in breast cancer, melanoma and glioblastoma cell aggregation revealed by antibodies with blocking activity.

Lusche DF, Klemme MR, Soll BA, Reis RJ, Forrest CC, Nop TS, Wessels DJ, Berger B, Glover R, Soll DR.

MAbs. 2019 May/Jun;11(4):691-708. doi: 10.1080/19420862.2019.1583987. Epub 2019 Apr 16.

PMID:
30810437
3.

Overexpressing TPTE2 (TPIP), a homolog of the human tumor suppressor gene PTEN, rescues the abnormal phenotype of the PTEN-/- mutant.

Lusche DF, Buchele EC, Russell KB, Soll BA, Vitolo MI, Klemme MR, Wessels DJ, Soll DR.

Oncotarget. 2018 Apr 20;9(30):21100-21121. doi: 10.18632/oncotarget.24941. eCollection 2018 Apr 20.

4.

Melanoma cells undergo aggressive coalescence in a 3D Matrigel model that is repressed by anti-CD44.

Wessels D, Lusche DF, Voss E, Kuhl S, Buchele EC, Klemme MR, Russell KB, Ambrose J, Soll BA, Bossler A, Milhem M, Goldman C, Soll DR.

PLoS One. 2017 Mar 6;12(3):e0173400. doi: 10.1371/journal.pone.0173400. eCollection 2017.

5.

4D Tumorigenesis Model for Quantitating Coalescence, Directed Cell Motility and Chemotaxis, Identifying Unique Cell Behaviors, and Testing Anticancer Drugs.

Kuhl S, Voss E, Scherer A, Lusche DF, Wessels D, Soll DR.

Methods Mol Biol. 2016;1407:229-50. doi: 10.1007/978-1-4939-3480-5_18.

PMID:
27271907
6.

Mediated coalescence: a possible mechanism for tumor cellular heterogeneity.

Ambrose J, Livitz M, Wessels D, Kuhl S, Lusche DF, Scherer A, Voss E, Soll DR.

Am J Cancer Res. 2015 Oct 15;5(11):3485-504. eCollection 2015.

7.

Quantitative Motion Analysis in Two and Three Dimensions.

Wessels DJ, Lusche DF, Kuhl S, Scherer A, Voss E, Soll DR.

Methods Mol Biol. 2016;1365:265-92. doi: 10.1007/978-1-4939-3124-8_14.

PMID:
26498790
8.

A computer-assisted 3D model for analyzing the aggregation of tumorigenic cells reveals specialized behaviors and unique cell types that facilitate aggregate coalescence.

Scherer A, Kuhl S, Wessels D, Lusche DF, Hanson B, Ambrose J, Voss E, Fletcher E, Goldman C, Soll DR.

PLoS One. 2015 Mar 19;10(3):e0118628. doi: 10.1371/journal.pone.0118628. eCollection 2015.

9.

PTEN redundancy: overexpressing lpten, a homolog of Dictyostelium discoideum ptenA, the ortholog of human PTEN, rescues all behavioral defects of the mutant ptenA-.

Lusche DF, Wessels D, Richardson NA, Russell KB, Hanson BM, Soll BA, Lin BH, Soll DR.

PLoS One. 2014 Sep 23;9(9):e108495. doi: 10.1371/journal.pone.0108495. eCollection 2014.

10.
11.

Myosin heavy chain kinases play essential roles in Ca2+, but not cAMP, chemotaxis and the natural aggregation of Dictyostelium discoideum.

Wessels D, Lusche DF, Steimle PA, Scherer A, Kuhl S, Wood K, Hanson B, Egelhoff TT, Soll DR.

J Cell Sci. 2012 Oct 15;125(Pt 20):4934-44. doi: 10.1242/jcs.112474. Epub 2012 Aug 16.

12.

The IplA Ca2+ channel of Dictyostelium discoideum is necessary for chemotaxis mediated through Ca2+, but not through cAMP, and has a fundamental role in natural aggregation.

Lusche DF, Wessels D, Scherer A, Daniels K, Kuhl S, Soll DR.

J Cell Sci. 2012 Apr 1;125(Pt 7):1770-83. doi: 10.1242/jcs.098301. Epub 2012 Feb 28.

13.

Survey of T-2 and HT-2 toxins by LC-MS/MS in oats and oat products from European oat mills in 2005-2009.

Pettersson H, Brown C, Hauk J, Hoth S, Meyer J, Wessels D.

Food Addit Contam Part B Surveill. 2011;4(2):110-5. doi: 10.1080/19393210.2011.561933. Epub 2011 May 11.

14.

Nhe1 is essential for potassium but not calcium facilitation of cell motility and the monovalent cation requirement for chemotactic orientation in Dictyostelium discoideum.

Lusche DF, Wessels D, Ryerson DE, Soll DR.

Eukaryot Cell. 2011 Mar;10(3):320-31. doi: 10.1128/EC.00255-10. Epub 2011 Jan 14.

15.

Ca2+ chemotaxis in Dictyostelium discoideum.

Scherer A, Kuhl S, Wessels D, Lusche DF, Raisley B, Soll DR.

J Cell Sci. 2010 Nov 1;123(Pt 21):3756-67. doi: 10.1242/jcs.068619. Epub 2010 Oct 12.

16.

An unconventional myosin required for cell polarization and chemotaxis.

Breshears LM, Wessels D, Soll DR, Titus MA.

Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6918-23. doi: 10.1073/pnas.0909796107. Epub 2010 Mar 29.

17.

2D and 3D quantitative analysis of cell motility and cytoskeletal dynamics.

Wessels D, Kuhl S, Soll DR.

Methods Mol Biol. 2009;586:315-35. doi: 10.1007/978-1-60761-376-3_18.

PMID:
19768439
18.

Light microscopy to image and quantify cell movement.

Wessels DJ, Kuhl S, Soll DR.

Methods Mol Biol. 2009;571:455-71. doi: 10.1007/978-1-60761-198-1_30.

PMID:
19763985
19.

How a cell crawls and the role of cortical myosin II.

Soll DR, Wessels D, Kuhl S, Lusche DF.

Eukaryot Cell. 2009 Sep;8(9):1381-96. doi: 10.1128/EC.00121-09. Epub 2009 Jul 24.

20.
21.

ClC-3 and IClswell are required for normal neutrophil chemotaxis and shape change.

Volk AP, Heise CK, Hougen JL, Artman CM, Volk KA, Wessels D, Soll DR, Nauseef WM, Lamb FS, Moreland JG.

J Biol Chem. 2008 Dec 5;283(49):34315-26. doi: 10.1074/jbc.M803141200. Epub 2008 Oct 7.

22.

Cofilin determines the migration behavior and turning frequency of metastatic cancer cells.

Sidani M, Wessels D, Mouneimne G, Ghosh M, Goswami S, Sarmiento C, Wang W, Kuhl S, El-Sibai M, Backer JM, Eddy R, Soll D, Condeelis J.

J Cell Biol. 2007 Nov 19;179(4):777-91.

23.

PTEN plays a role in the suppression of lateral pseudopod formation during Dictyostelium motility and chemotaxis.

Wessels D, Lusche DF, Kuhl S, Heid P, Soll DR.

J Cell Sci. 2007 Aug 1;120(Pt 15):2517-31. Epub 2007 Jul 10.

24.
25.

Towards a molecular understanding of human diseases using Dictyostelium discoideum.

Williams RS, Boeckeler K, Gräf R, Müller-Taubenberger A, Li Z, Isberg RR, Wessels D, Soll DR, Alexander H, Alexander S.

Trends Mol Med. 2006 Sep;12(9):415-24. Epub 2006 Aug 4. Review.

PMID:
16890490
26.

Evaluation of the safety and pharmacodynamics of Hematide, a novel erythropoietic agent, in a phase 1, double-blind, placebo-controlled, dose-escalation study in healthy volunteers.

Stead RB, Lambert J, Wessels D, Iwashita JS, Leuther KK, Woodburn KW, Schatz PJ, Okamoto DM, Naso R, Duliege AM.

Blood. 2006 Sep 15;108(6):1830-4. Epub 2006 May 23.

PMID:
16720830
27.

Plethysmography and impulse oscillometry assessment of tiotropium and ipratropium bromide; a randomized, double-blind, placebo-controlled, cross-over study in healthy subjects.

Singh D, Tal-Singer R, Faiferman I, Lasenby S, Henderson A, Wessels D, Goosen A, Dallow N, Vessey R, Goldman M.

Br J Clin Pharmacol. 2006 Apr;61(4):398-404.

28.
29.
30.

An investigation of the relationship between air emissions of volatile organic compounds and the incidence of cancer in Indiana counties.

Boeglin ML, Wessels D, Henshel D.

Environ Res. 2006 Feb;100(2):242-54. Epub 2005 Jun 29.

PMID:
15992796
31.

Computer-assisted analysis of filopod formation and the role of myosin II heavy chain phosphorylation in Dictyostelium.

Heid PJ, Geiger J, Wessels D, Voss E, Soll DR.

J Cell Sci. 2005 May 15;118(Pt 10):2225-37. Epub 2005 Apr 26.

32.

RasGEF-containing proteins GbpC and GbpD have differential effects on cell polarity and chemotaxis in Dictyostelium.

Bosgraaf L, Waijer A, Engel R, Visser AJ, Wessels D, Soll D, van Haastert PJ.

J Cell Sci. 2005 May 1;118(Pt 9):1899-910. Epub 2005 Apr 12.

33.

Intracellular role of adenylyl cyclase in regulation of lateral pseudopod formation during Dictyostelium chemotaxis.

Stepanovic V, Wessels D, Daniels K, Loomis WF, Soll DR.

Eukaryot Cell. 2005 Apr;4(4):775-86.

34.

Sphingosine-1-phosphate plays a role in the suppression of lateral pseudopod formation during Dictyostelium discoideum cell migration and chemotaxis.

Kumar A, Wessels D, Daniels KJ, Alexander H, Alexander S, Soll DR.

Cell Motil Cytoskeleton. 2004 Dec;59(4):227-41.

PMID:
15476260
35.

The role of myosin heavy chain phosphorylation in Dictyostelium motility, chemotaxis and F-actin localization.

Heid PJ, Wessels D, Daniels KJ, Gibson DP, Zhang H, Voss E, Soll DR.

J Cell Sci. 2004 Sep 15;117(Pt 20):4819-35. Epub 2004 Aug 31.

36.

RasC plays a role in transduction of temporal gradient information in the cyclic-AMP wave of Dictyostelium discoideum.

Wessels D, Brincks R, Kuhl S, Stepanovic V, Daniels KJ, Weeks G, Lim CJ, Spiegelman G, Fuller D, Iranfar N, Loomis WF, Soll DR.

Eukaryot Cell. 2004 Jun;3(3):646-62.

37.

The chemotaxis defect of Shwachman-Diamond Syndrome leukocytes.

Stepanovic V, Wessels D, Goldman FD, Geiger J, Soll DR.

Cell Motil Cytoskeleton. 2004 Mar;57(3):158-74.

PMID:
14743349
38.
39.

Equipotency of insulin glargine and regular human insulin on glucose disposal in healthy subjects following intravenous infusion.

Scholtz HE, Pretorius SG, Wessels DH, Venter C, Potgieter MA, Becker RH.

Acta Diabetol. 2003 Dec;40(4):156-62.

PMID:
14740274
40.
41.

Computer-assisted reconstruction and motion analysis of the three-dimensional cell.

Soll DR, Wessels D, Heid PJ, Voss E.

ScientificWorldJournal. 2003 Sep 3;3:827-41. Review.

42.

Shared, unique and redundant functions of three members of the class I myosins (MyoA, MyoB and MyoF) in motility and chemotaxis in Dictyostelium.

Falk DL, Wessels D, Jenkins L, Pham T, Kuhl S, Titus MA, Soll DR.

J Cell Sci. 2003 Oct 1;116(Pt 19):3985-99.

43.

A contextual framework for characterizing motility and chemotaxis mutants in Dictyostelium discoideum.

Soll DR, Wessels D, Heid PJ, Zhang H.

J Muscle Res Cell Motil. 2002;23(7-8):659-72. Review.

PMID:
12952065
44.

Human polymorphonuclear leukocytes respond to waves of chemoattractant, like Dictyostelium.

Geiger J, Wessels D, Soll DR.

Cell Motil Cytoskeleton. 2003 Sep;56(1):27-44.

PMID:
12905529
45.

Asynchronous cell cycle and asymmetric vacuolar inheritance in true hyphae of Candida albicans.

Barelle CJ, Bohula EA, Kron SJ, Wessels D, Soll DR, Schäfer A, Brown AJ, Gow NA.

Eukaryot Cell. 2003 Jun;2(3):398-410.

46.

Biotransformation of insulin glargine after subcutaneous injection in healthy subjects.

Kuerzel GU, Shukla U, Scholtz HE, Pretorius SG, Wessels DH, Venter C, Potgieter MA, Lang AM, Koose T, Bernhardt E.

Curr Med Res Opin. 2003;19(1):34-40.

PMID:
12661778
47.

Regulation of caldesmon activity by Cdc2 kinase plays an important role in maintaining membrane cortex integrity during cell division.

Li Y, Wessels D, Wang T, Lin JL, Soll DR, Lin JJ.

Cell Mol Life Sci. 2003 Jan;60(1):198-211.

PMID:
12613668
48.

Constitutively active protein kinase A disrupts motility and chemotaxis in Dictyostelium discoideum.

Zhang H, Heid PJ, Wessels D, Daniels KJ, Pham T, Loomis WF, Soll DR.

Eukaryot Cell. 2003 Feb;2(1):62-75.

49.

Cell biology of mating in Candida albicans.

Lockhart SR, Daniels KJ, Zhao R, Wessels D, Soll DR.

Eukaryot Cell. 2003 Feb;2(1):49-61.

50.

Pharmacokinetics and absolute oral bioavailability of an 800-mg oral dose of telithromycin in healthy young and elderly volunteers.

Perret C, Lenfant B, Weinling E, Wessels DH, Scholtz HE, Montay G, Sultan E.

Chemotherapy. 2002 Dec;48(5):217-23.

PMID:
12476037

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