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CoQ10 and Cognition a Review and Study Protocol for a 90-Day Randomized Controlled Trial Investigating the Cognitive Effects of Ubiquinol in the Healthy Elderly.

Stough C, Nankivell M, Camfield DA, Perry NL, Pipingas A, Macpherson H, Wesnes K, Ou R, Hare D, de Haan J, Head G, Lansjoen P, Langsjoen A, Tan B, Pase MP, King R, Rowsell R, Zwalf O, Rathner Y, Cooke M, Rosenfeldt F.

Front Aging Neurosci. 2019 May 29;11:103. doi: 10.3389/fnagi.2019.00103. eCollection 2019.


D-Cycloserine Improves Difficult Discriminations in a Pattern Separation Task in Alzheimer's Disease Patients with Dementia.

Goetghebeur PJD, Wesnes KA, Targum SD.

J Alzheimers Dis. 2019;69(2):377-383. doi: 10.3233/JAD-181094.


Mild Behavioral Impairment as a Marker of Cognitive Decline in Cognitively Normal Older Adults.

Creese B, Brooker H, Ismail Z, Wesnes KA, Hampshire A, Khan Z, Megalogeni M, Corbett A, Aarsland D, Ballard C.

Am J Geriatr Psychiatry. 2019 Feb 2. pii: S1064-7481(19)30227-1. doi: 10.1016/j.jagp.2019.01.215. [Epub ahead of print]


The relationship between the frequency of number-puzzle use and baseline cognitive function in a large online sample of adults aged 50 and over.

Brooker H, Wesnes KA, Ballard C, Hampshire A, Aarsland D, Khan Z, Stenton R, Megalogeni M, Corbett A.

Int J Geriatr Psychiatry. 2019 Jul;34(7):932-940. doi: 10.1002/gps.5085. Epub 2019 Feb 28.


An online investigation of the relationship between the frequency of word puzzle use and cognitive function in a large sample of older adults.

Brooker H, Wesnes KA, Ballard C, Hampshire A, Aarsland D, Khan Z, Stenton R, McCambridge L, Corbett A.

Int J Geriatr Psychiatry. 2019 Jul;34(7):921-931. doi: 10.1002/gps.5033. Epub 2019 May 16.


The Cognitive Ageing, Nutrition and Neurogenesis (CANN) trial: Design and progress.

Irvine MA, Scholey A, King R, Gillings R, Vauzour D, Demichele SJ, Das T, Wesnes KA, Sutton BP, Cassidy A, Pipingas A, Potter JF, Johnson G, White D, Larsen R, Cohen NJ, Minihane AM.

Alzheimers Dement (N Y). 2018 Sep 5;4:591-601. doi: 10.1016/j.trci.2018.08.001. eCollection 2018.


Investigating the relationship between age of onset of depressive disorder and cognitive function.

Eraydin IE, Mueller C, Corbett A, Ballard C, Brooker H, Wesnes K, Aarsland D, Huntley J.

Int J Geriatr Psychiatry. 2019 Jan;34(1):38-46. doi: 10.1002/gps.4979. Epub 2018 Sep 27.


The effects of the selective muscarinic M3 receptor antagonist darifenacin, and of hyoscine (scopolamine), on motion sickness, skin conductance & cognitive function.

Golding JF, Wesnes KA, Leaker BR.

Br J Clin Pharmacol. 2018 Jul;84(7):1535-1543. doi: 10.1111/bcp.13579. Epub 2018 Apr 19.


Impaired verbal episodic memory in healthy older adults is marked by increased F2-Isoprostanes.

Downey LA, Simpson T, Timmer J, Nolidin K, Croft K, Wesnes KA, Scholey A, Deleuil S, Stough C.

Prostaglandins Leukot Essent Fatty Acids. 2018 Feb;129:32-37. doi: 10.1016/j.plefa.2018.02.001. Epub 2018 Feb 3.


A randomised double-blind placebo-controlled pilot trial of a combined extract of sage, rosemary and melissa, traditional herbal medicines, on the enhancement of memory in normal healthy subjects, including influence of age.

Perry NSL, Menzies R, Hodgson F, Wedgewood P, Howes MR, Brooker HJ, Wesnes KA, Perry EK.

Phytomedicine. 2018 Jan 15;39:42-48. doi: 10.1016/j.phymed.2017.08.015. Epub 2017 Aug 18.


The impact of blackcurrant juice on attention, mood and brain wave spectral activity in young healthy volunteers.

Watson AW, Okello EJ, Brooker HJ, Lester S, McDougall GJ, Wesnes KA.

Nutr Neurosci. 2019 Aug;22(8):596-606. doi: 10.1080/1028415X.2017.1420539. Epub 2018 Jan 17.


Spearmint Extract Improves Working Memory in Men and Women with Age-Associated Memory Impairment.

Herrlinger KA, Nieman KM, Sanoshy KD, Fonseca BA, Lasrado JA, Schild AL, Maki KC, Wesnes KA, Ceddia MA.

J Altern Complement Med. 2018 Jan;24(1):37-47. doi: 10.1089/acm.2016.0379. Epub 2018 Jan 9.


Poor cognitive ageing: Vulnerabilities, mechanisms and the impact of nutritional interventions.

Miquel S, Champ C, Day J, Aarts E, Bahr BA, Bakker M, Bánáti D, Calabrese V, Cederholm T, Cryan J, Dye L, Farrimond JA, Korosi A, Layé S, Maudsley S, Milenkovic D, Mohajeri MH, Sijben J, Solomon A, Spencer JPE, Thuret S, Vanden Berghe W, Vauzour D, Vellas B, Wesnes K, Willatts P, Wittenberg R, Geurts L.

Ageing Res Rev. 2018 Mar;42:40-55. doi: 10.1016/j.arr.2017.12.004. Epub 2017 Dec 15. Review.


Tolerability of ORM-12741 and effects on episodic memory in patients with Alzheimer's disease.

Rinne JO, Wesnes K, Cummings JL, Hakulinen P, Hallikainen M, Hänninen J, Murphy M, Riordan H, Scheinin M, Soininen H, Rouru J.

Alzheimers Dement (N Y). 2016 Dec 8;3(1):1-9. doi: 10.1016/j.trci.2016.11.004. eCollection 2017 Jan.


Does attentional dysfunction and thalamic atrophy predict decline in dementia with Lewy bodies?

Watson R, Colloby SJ, Blamire AM, Wesnes KA, Wood J, O'Brien JT.

Parkinsonism Relat Disord. 2017 Dec;45:69-74. doi: 10.1016/j.parkreldis.2017.10.006. Epub 2017 Oct 9.


Online assessment of risk factors for dementia and cognitive function in healthy adults.

Huntley J, Corbett A, Wesnes K, Brooker H, Stenton R, Hampshire A, Ballard C.

Int J Geriatr Psychiatry. 2018 Feb;33(2):e286-e293. doi: 10.1002/gps.4790. Epub 2017 Sep 27.


Homocysteine, Tryptophan, and Cognition in the Very Old.

Mendonça N, Granic A, Mathers JC, Martin-Ruiz C, Wesnes KA, Seal CJ, Jagger C, Hill TR.

J Am Med Dir Assoc. 2017 Oct 1;18(10):895-896. doi: 10.1016/j.jamda.2017.07.010. Epub 2017 Aug 23. No abstract available.


One-Carbon Metabolism Biomarkers and Cognitive Decline in the Very Old: The Newcastle 85+ Study.

Mendonça N, Granic A, Mathers JC, Martin-Ruiz C, Wesnes KA, Seal CJ, Jagger C, Hill TR.

J Am Med Dir Assoc. 2017 Sep 1;18(9):806.e19-806.e27. doi: 10.1016/j.jamda.2017.05.008. Epub 2017 Jun 21.


Longitudinal changes in global and domain specific cognitive function in the very-old: findings from the Newcastle 85+ Study.

Stephan BCM, Muniz-Terrera G, Granic A, Collerton J, Davies K, Saxby BK, Wesnes KA, Kirkwood TBL, Jagger C.

Int J Geriatr Psychiatry. 2018 Feb;33(2):298-306. doi: 10.1002/gps.4743. Epub 2017 Jun 22.


Effects of aging and depression on mnemonic discrimination ability.

Camfield DA, Fontana R, Wesnes KA, Mills J, Croft RJ.

Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2018 May;25(3):464-483. doi: 10.1080/13825585.2017.1325827. Epub 2017 May 16.


Performance-based and Observational Assessments in Clinical Trials Across the Alzheimer's Disease Spectrum.

Harvey PD, Cosentino S, Curiel R, Goldberg TE, Kaye J, Loewenstein D, Marson D, Salmon D, Wesnes K, Posner H.

Innov Clin Neurosci. 2017 Feb 1;14(1-2):30-39. eCollection 2017 Jan-Feb. Review.


Outcomes Assessment in Clinical Trials of Alzheimer's Disease and its Precursors: Readying for Short-term and Long-term Clinical Trial Needs.

Posner H, Curiel R, Edgar C, Hendrix S, Liu E, Loewenstein DA, Morrison G, Shinobu L, Wesnes K, Harvey PD.

Innov Clin Neurosci. 2017 Feb 1;14(1-2):22-29. eCollection 2017 Jan-Feb.


Physical activity is associated with a decreased multiple sclerosis risk: The EnvIMS study.

Wesnes K, Myhr KM, Riise T, Cortese M, Pugliatti M, Boström I, Landtblom AM, Wolfson C, Bjørnevik K.

Mult Scler. 2018 Feb;24(2):150-157. doi: 10.1177/1352458517694088. Epub 2017 Feb 1.


Effects of the Red Bull energy drink on cognitive function and mood in healthy young volunteers.

Wesnes KA, Brooker H, Watson AW, Bal W, Okello E.

J Psychopharmacol. 2017 Feb;31(2):211-221. doi: 10.1177/0269881116681459. Epub 2016 Dec 14.


Utility, reliability, sensitivity and validity of an online test system designed to monitor changes in cognitive function in clinical trials.

Wesnes KA, Brooker H, Ballard C, McCambridge L, Stenton R, Corbett A.

Int J Geriatr Psychiatry. 2017 Dec;32(12):e83-e92. doi: 10.1002/gps.4659. Epub 2017 Jan 27.


The woman who did not recognise her own face.

Myren-Svelstad S, Meisingset TW, Wesnes K.

Tidsskr Nor Laegeforen. 2016 Nov 22;136(21):1815-1818. eCollection 2016 Nov. English, Norwegian. No abstract available.


Predicting Risk of Cognitive Decline in Very Old Adults Using Three Models: The Framingham Stroke Risk Profile; the Cardiovascular Risk Factors, Aging, and Dementia Model; and Oxi-Inflammatory Biomarkers.

Harrison SL, de Craen AJ, Kerse N, Teh R, Granic A, Davies K, Wesnes KA, den Elzen WP, Gussekloo J, Kirkwood TB, Robinson L, Jagger C, Siervo M, Stephan BC.

J Am Geriatr Soc. 2017 Feb;65(2):381-389. doi: 10.1111/jgs.14532. Epub 2016 Nov 14.


Effects of levomilnacipran extended-release on major depressive disorder patients with cognitive impairments: post-hoc analysis of a phase III study.

Wesnes KA, Gommoll C, Chen C, Sambunaris A, McIntyre RS, Harvey PD.

Int Clin Psychopharmacol. 2017 Mar;32(2):72-79. doi: 10.1097/YIC.0000000000000157.


Nutrition for the ageing brain: Towards evidence for an optimal diet.

Vauzour D, Camprubi-Robles M, Miquel-Kergoat S, Andres-Lacueva C, Bánáti D, Barberger-Gateau P, Bowman GL, Caberlotto L, Clarke R, Hogervorst E, Kiliaan AJ, Lucca U, Manach C, Minihane AM, Mitchell ES, Perneczky R, Perry H, Roussel AM, Schuermans J, Sijben J, Spencer JP, Thuret S, van de Rest O, Vandewoude M, Wesnes K, Williams RJ, Williams RS, Ramirez M.

Ageing Res Rev. 2017 May;35:222-240. doi: 10.1016/j.arr.2016.09.010. Epub 2016 Oct 3. Review.


The effect of desvenlafaxine on cognitive functioning in employed outpatients with major depressive disorder: a substudy of a randomized, double-blind, placebo-controlled trial.

Reddy S, Fayyad R, Edgar CJ, Guico-Pabia CJ, Wesnes K.

J Psychopharmacol. 2016 Jun;30(6):559-67. doi: 10.1177/0269881116631649. Epub 2016 Mar 23.


Relationships Among Cognitive Function and Cerebral Blood Flow, Oxidative Stress, and Inflammation in Older Heart Failure Patients.

Kure CE, Rosenfeldt FL, Scholey AB, Pipingas A, Kaye DM, Bergin PJ, Croft KD, Wesnes KA, Myers SP, Stough C.

J Card Fail. 2016 Jul;22(7):548-59. doi: 10.1016/j.cardfail.2016.03.006. Epub 2016 Mar 18.


Single-Dose Interaction Study of the Arginine Vasopressin Type 1B Receptor Antagonist ABT-436 and Alcohol in Moderate Alcohol Drinkers.

Katz DA, Locke C, Liu W, Zhang J, Achari R, Wesnes KA, Tracy KA.

Alcohol Clin Exp Res. 2016 Apr;40(4):838-45. doi: 10.1111/acer.12996. Epub 2016 Mar 10.


Hearing loss and cognition in the Busselton Baby Boomer cohort: An epidemiological study.

Bucks RS, Dunlop PD, Taljaard DS, Brennan-Jones CG, Hunter M, Wesnes K, Eikelboom RH.

Laryngoscope. 2016 Oct;126(10):2367-75. doi: 10.1002/lary.25896. Epub 2016 Feb 24.


Differences in memory function between 5-HT1A receptor genotypes in patients with major depressive disorder.

Wesnes KA, Hopkins SC, Brooker HJ, Koblan KS.

CNS Spectr. 2016 Oct;21(5):379-384. Epub 2016 Jan 19.


Norms for healthy adults aged 18-87 years for the Cognitive Drug Research System: An automated set of tests of attention, information processing and memory for use in clinical trials.

Wesnes KA, McNamara C, Annas P.

J Psychopharmacol. 2016 Mar;30(3):263-72. doi: 10.1177/0269881115625116. Epub 2016 Jan 11.


Cognitive effects of adjunctive perampanel for partial-onset seizures: A randomized trial.

Meador KJ, Yang H, Piña-Garza JE, Laurenza A, Kumar D, Wesnes KA.

Epilepsia. 2016 Feb;57(2):243-51. doi: 10.1111/epi.13279. Epub 2016 Jan 1.


Does Self-Efficacy Affect Cognitive Performance in Persons with Clinically Isolated Syndrome and Early Relapsing Remitting Multiple Sclerosis?

Jongen PJ, Wesnes K, van Geel B, Pop P, Schrijver H, Visser LH, Gilhuis HJ, Sinnige LG, Brands AM.

Mult Scler Int. 2015;2015:960282. doi: 10.1155/2015/960282. Epub 2015 Apr 29.


Is there an association between metabolic syndrome and cognitive function in very old adults? The Newcastle 85+ Study.

Harrison SL, Stephan BC, Siervo M, Granic A, Davies K, Wesnes KA, Kirkwood TB, Robinson L, Jagger C.

J Am Geriatr Soc. 2015 Apr;63(4):667-75. doi: 10.1111/jgs.13358. Epub 2015 Apr 8.


Improved working memory performance following administration of a single dose of American ginseng (Panax quinquefolius L.) to healthy middle-age adults.

Ossoukhova A, Owen L, Savage K, Meyer M, Ibarra A, Roller M, Pipingas A, Wesnes K, Scholey A.

Hum Psychopharmacol. 2015 Mar;30(2):108-22. doi: 10.1002/hup.2463.


[Cerebral edema after status epilepticus].

Wesnes K, Lian KK, Kvistad KA.

Tidsskr Nor Laegeforen. 2015 Mar 10;135(5):439. doi: 10.4045/tidsskr.14.1422. eCollection 2015 Mar 10. Norwegian. No abstract available.


Practice effects due to serial cognitive assessment: Implications for preclinical Alzheimer's disease randomized controlled trials.

Goldberg TE, Harvey PD, Wesnes KA, Snyder PJ, Schneider LS.

Alzheimers Dement (Amst). 2015 Mar 29;1(1):103-11. doi: 10.1016/j.dadm.2014.11.003. eCollection 2015 Mar.


Moving beyond the pros and cons of automating cognitive testing in pathological aging and dementia: the case for equal opportunity.

Wesnes KA.

Alzheimers Res Ther. 2014 Aug 29;6(5):58. doi: 10.1186/s13195-014-0058-1. eCollection 2014. Review.


Body size and the risk of multiple sclerosis in Norway and Italy: the EnvIMS study.

Wesnes K, Riise T, Casetta I, Drulovic J, Granieri E, Holmøy T, Kampman MT, Landtblom AM, Lauer K, Lossius A, Magalhaes S, Pekmezovic T, Bjørnevik K, Wolfson C, Pugliatti M, Myhr KM.

Mult Scler. 2015 Apr;21(4):388-95. doi: 10.1177/1352458514546785. Epub 2014 Sep 2.


Atomoxetine for attention deficits following traumatic brain injury: results from a randomized controlled trial.

Ripley DL, Morey CE, Gerber D, Harrison-Felix C, Brenner LA, Pretz CR, Cusick C, Wesnes K.

Brain Inj. 2014;28(12):1514-22. doi: 10.3109/02699052.2014.919530. Epub 2014 Sep 2.


Serum 25-hydroxyvitamin D and cognitive decline in the very old: the Newcastle 85+ Study.

Granic A, Hill TR, Kirkwood TB, Davies K, Collerton J, Martin-Ruiz C, von Zglinicki T, Saxby BK, Wesnes KA, Collerton D, Mathers JC, Jagger C.

Eur J Neurol. 2015 Jan;22(1):106-15, e6-7. doi: 10.1111/ene.12539. Epub 2014 Aug 13.


Functional Living in Older Adults With Type 2 Diabetes: Executive Functioning, Dual Task Performance, and the Impact on Postural Stability and Motor Control.

Smith MA, Else JE, Paul L, Foster JK, Walker M, Wesnes KA, Riby LM.

J Aging Health. 2014 Aug;26(5):841-859. Epub 2014 Jun 4.


Relationship between working hours and power of attention, memory, fatigue, depression and self-efficacy one year after diagnosis of clinically isolated syndrome and relapsing remitting multiple sclerosis.

Jongen PJ, Wesnes K, van Geel B, Pop P, Sanders E, Schrijver H, Visser LH, Gilhuis HJ, Sinnige LG, Brands AM; COGNISEC Study Group.

PLoS One. 2014 May 1;9(5):e96444. doi: 10.1371/journal.pone.0096444. eCollection 2014. Erratum in: PLoS One. 2014;9(8):e105654.


Memantine improves attention and episodic memory in Parkinson's disease dementia and dementia with Lewy bodies.

Wesnes KA, Aarsland D, Ballard C, Londos E.

Int J Geriatr Psychiatry. 2015 Jan;30(1):46-54. doi: 10.1002/gps.4109. Epub 2014 Apr 16.


Criteria for validation and selection of cognitive tests for investigating the effects of foods and nutrients.

de Jager CA, Dye L, de Bruin EA, Butler L, Fletcher J, Lamport DJ, Latulippe ME, Spencer JP, Wesnes K.

Nutr Rev. 2014 Mar;72(3):162-79. Review.


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