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Items: 25

1.

Clinical efficacy of ruxolitinib and chemotherapy in a child with Philadelphia chromosome-like acute lymphoblastic leukemia with GOLGA5-JAK2 fusion and induction failure.

Ding YY, Stern JW, Jubelirer TF, Wertheim GB, Lin F, Chang F, Gu Z, Mullighan CG, Li Y, Harvey RC, Chen IM, Willman CL, Hunger SP, Li MM, Tasian SK.

Haematologica. 2018 Sep;103(9):e427-e431. doi: 10.3324/haematol.2018.192088. Epub 2018 May 17. No abstract available.

2.

A PERK-miR-211 axis suppresses circadian regulators and protein synthesis to promote cancer cell survival.

Bu Y, Yoshida A, Chitnis N, Altman BJ, Tameire F, Oran A, Gennaro V, Armeson KE, McMahon SB, Wertheim GB, Dang CV, Ruggero D, Koumenis C, Fuchs SY, Diehl JA.

Nat Cell Biol. 2018 Jan;20(1):104-115. doi: 10.1038/s41556-017-0006-y. Epub 2017 Dec 11.

3.

MAFB enhances oncogenic Notch signaling in T cell acute lymphoblastic leukemia.

Pajcini KV, Xu L, Shao L, Petrovic J, Palasiewicz K, Ohtani Y, Bailis W, Lee C, Wertheim GB, Mani R, Muthusamy N, Li Y, Meijerink JPP, Blacklow SC, Faryabi RB, Cherry S, Pear WS.

Sci Signal. 2017 Nov 14;10(505). pii: eaam6846. doi: 10.1126/scisignal.aam6846.

4.

Severe Mucha-Habermann-Like Ulceronecrotic Skin Disease in T-Cell Acute Lymphoblastic Leukemia Responsive to Basiliximab and Stem Cell Transplant.

Orenstein LAV, Coughlin CC, Flynn AT, Pillai V, Boos MD, Wertheim GB, Treat JR, Teachey DT.

Pediatr Dermatol. 2017 Sep;34(5):e265-e270. doi: 10.1111/pde.13235.

PMID:
28884915
5.

Microsphere-Based Assessment of DNA Methylation for AML Prognosis.

Wertheim GBW, Luskin MR, Carroll M, Master SR.

Methods Mol Biol. 2017;1633:125-136. doi: 10.1007/978-1-4939-7142-8_8.

PMID:
28735484
6.

Cytochemical Staining.

Paessler ME, Helfrich M, Wertheim GBW.

Methods Mol Biol. 2017;1633:19-32. doi: 10.1007/978-1-4939-7142-8_2. Review.

PMID:
28735478
7.

Cytosine Deaminase APOBEC3A Sensitizes Leukemia Cells to Inhibition of the DNA Replication Checkpoint.

Green AM, Budagyan K, Hayer KE, Reed MA, Savani MR, Wertheim GB, Weitzman MD.

Cancer Res. 2017 Sep 1;77(17):4579-4588. doi: 10.1158/0008-5472.CAN-16-3394. Epub 2017 Jun 27.

8.

NPM1 for MRD? Droplet Like It's Hot!

Wertheim GBW, Bagg A.

J Mol Diagn. 2017 Jul;19(4):498-501. doi: 10.1016/j.jmoldx.2017.04.008.

PMID:
28645444
9.

High incidence of Philadelphia chromosome-like acute lymphoblastic leukemia in older adults with B-ALL.

Tasian SK, Hurtz C, Wertheim GB, Bailey NG, Lim MS, Harvey RC, Chen IM, Willman CL, Astles R, Zebrowski A, Reshmi SC, Li MM, Frey NV, Luger SM, Carroll M, Perl AE.

Leukemia. 2017 Apr;31(4):981-984. doi: 10.1038/leu.2016.375. Epub 2016 Dec 9. No abstract available.

10.

Incidental EBV-positivity in paediatric post-transplant specimens demonstrates the need for stringent criteria for diagnosing post-transplant lymphoproliferative disorders.

King RL, Paessler ME, Howard MT, Wertheim GB.

J Clin Pathol. 2017 Mar;70(3):270-273. doi: 10.1136/jclinpath-2016-203924. Epub 2016 Nov 15.

PMID:
27852687
11.

Validation of a clinical assay of multi-locus DNA methylation for prognosis of newly diagnosed AML.

Dinardo CD, Luskin MR, Carroll M, Smith C, Harrison J, Pierce S, Kornblau S, Konopleva M, Kadia T, Kantarjian H, Wertheim GB, Master SR.

Am J Hematol. 2017 Feb;92(2):E14-E15. doi: 10.1002/ajh.24597. No abstract available.

12.

A clinical measure of DNA methylation predicts outcome in de novo acute myeloid leukemia.

Luskin MR, Gimotty PA, Smith C, Loren AW, Figueroa ME, Harrison J, Sun Z, Tallman MS, Paietta EM, Litzow MR, Melnick AM, Levine RL, Fernandez HF, Luger SM, Carroll M, Master SR, Wertheim GB.

JCI Insight. 2016 Jun 16;1(9). pii: e87323.

13.

Mixed Phenotype Acute Leukemia with Low Hypodiploidy in a Pediatric Patient.

Salazar EG, Wertheim GB, Biegel JA, Hwang W, Tasian SK, Rheingold SR.

J Pediatr Oncol. 2015;3(1):24-28. Epub 2015 Mar 25.

14.

B Cell-Intrinsic Expression of the HuR RNA-Binding Protein Is Required for the T Cell-Dependent Immune Response In Vivo.

DeMicco A, Naradikian MS, Sindhava VJ, Yoon JH, Gorospe M, Wertheim GB, Cancro MP, Bassing CH.

J Immunol. 2015 Oct 1;195(7):3449-62. doi: 10.4049/jimmunol.1500512. Epub 2015 Aug 28.

15.

Validation of DNA methylation to predict outcome in acute myeloid leukemia by use of xMELP.

Wertheim GB, Smith C, Luskin M, Rager A, Figueroa ME, Carroll M, Master SR.

Clin Chem. 2015 Jan;61(1):249-58. doi: 10.1373/clinchem.2014.229781. Epub 2014 Oct 27.

16.

Ikaros imposes a barrier to CD8+ T cell differentiation by restricting autocrine IL-2 production.

O'Brien S, Thomas RM, Wertheim GB, Zhang F, Shen H, Wells AD.

J Immunol. 2014 Jun 1;192(11):5118-29. doi: 10.4049/jimmunol.1301992. Epub 2014 Apr 28.

17.

The Notch1 transcriptional activation domain is required for development and reveals a novel role for Notch1 signaling in fetal hematopoietic stem cells.

Gerhardt DM, Pajcini KV, D'altri T, Tu L, Jain R, Xu L, Chen MJ, Rentschler S, Shestova O, Wertheim GB, Tobias JW, Kluk M, Wood AW, Aster JC, Gimotty PA, Epstein JA, Speck N, Bigas A, Pear WS.

Genes Dev. 2014 Mar 15;28(6):576-93. doi: 10.1101/gad.227496.113.

18.

Microsphere-based multiplex analysis of DNA methylation in acute myeloid leukemia.

Wertheim GB, Smith C, Figueroa ME, Kalos M, Bagg A, Carroll M, Master SR.

J Mol Diagn. 2014 Mar;16(2):207-15. doi: 10.1016/j.jmoldx.2013.10.010. Epub 2013 Dec 25.

19.

Molecular-based classification of acute myeloid leukemia and its role in directing rational therapy: personalized medicine for profoundly promiscuous proliferations.

Wertheim GB, Hexner E, Bagg A.

Mol Diagn Ther. 2012 Dec;16(6):357-69. doi: 10.1007/s40291-012-0009-0. Review.

PMID:
23184342
20.

Molecular diagnostics of acute myeloid leukemia: it's a (next) generational thing.

Wertheim GB, Daber R, Bagg A.

J Mol Diagn. 2013 Jan;15(1):27-30. doi: 10.1016/j.jmoldx.2012.08.002. Epub 2012 Nov 16.

PMID:
23159532
21.

Minimal residual disease testing to predict relapse following transplant for AML and high-grade myelodysplastic syndromes.

Wertheim GB, Bagg A.

Expert Rev Mol Diagn. 2011 May;11(4):361-6. doi: 10.1586/erm.11.19.

PMID:
21545254
22.

The Snf1-related kinase, Hunk, is essential for mammary tumor metastasis.

Wertheim GB, Yang TW, Pan TC, Ramne A, Liu Z, Gardner HP, Dugan KD, Kristel P, Kreike B, van de Vijver MJ, Cardiff RD, Reynolds C, Chodosh LA.

Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15855-60. doi: 10.1073/pnas.0906993106. Epub 2009 Aug 28.

23.

A novel doxycycline-inducible system for the transgenic analysis of mammary gland biology.

Gunther EJ, Belka GK, Wertheim GB, Wang J, Hartman JL, Boxer RB, Chodosh LA.

FASEB J. 2002 Mar;16(3):283-92.

PMID:
11874978
24.

Developmental role of the SNF1-related kinase Hunk in pregnancy-induced changes in the mammary gland.

Gardner HP, Belka GK, Wertheim GB, Hartman JL, Ha SI, Gimotty PA, Marquis ST, Chodosh LA.

Development. 2000 Oct;127(20):4493-509.

25.

Cloning and characterization of Hunk, a novel mammalian SNF1-related protein kinase.

Gardner HP, Wertheim GB, Ha SI, Copeland NG, Gilbert DJ, Jenkins NA, Marquis ST, Chodosh LA.

Genomics. 2000 Jan 1;63(1):46-59.

PMID:
10662544

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