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Items: 12

1.

N-desmethylclozapine (NDMC) is an antagonist at the human native muscarinic M(1) receptor.

Thomas DR, Dada A, Jones GA, Deisz RA, Gigout S, Langmead CJ, Werry TD, Hendry N, Hagan JJ, Davies CH, Watson JM.

Neuropharmacology. 2010 Jun;58(8):1206-14. doi: 10.1016/j.neuropharm.2010.02.017. Epub 2010 Mar 3.

PMID:
20206188
2.

Performance of mouse neural stem cells as a screening reagent: characterization of PAC1 activity in medium-throughput functional assays.

Lodge AP, Langmead CJ, Daniel G, Anderson GW, Werry TD.

J Biomol Screen. 2010 Feb;15(2):159-68. doi: 10.1177/1087057109355468. Epub 2009 Dec 30.

PMID:
20042531
3.

Pharmacology of 5HT(2C) receptor-mediated ERK1/2 phosphorylation: agonist-specific activation pathways and the impact of RNA editing.

Werry TD, Stewart GD, Crouch MF, Watts A, Sexton PM, Christopoulos A.

Biochem Pharmacol. 2008 Nov 15;76(10):1276-87. doi: 10.1016/j.bcp.2008.08.024. Epub 2008 Aug 31.

PMID:
18812172
4.

Receptor activity-modifying proteins differentially modulate the G protein-coupling efficiency of amylin receptors.

Morfis M, Tilakaratne N, Furness SG, Christopoulos G, Werry TD, Christopoulos A, Sexton PM.

Endocrinology. 2008 Nov;149(11):5423-31. doi: 10.1210/en.2007-1735. Epub 2008 Jul 3.

PMID:
18599553
5.

RNA editing of the serotonin 5HT2C receptor and its effects on cell signalling, pharmacology and brain function.

Werry TD, Loiacono R, Sexton PM, Christopoulos A.

Pharmacol Ther. 2008 Jul;119(1):7-23. doi: 10.1016/j.pharmthera.2008.03.012. Epub 2008 May 2. Review.

PMID:
18554725
6.

The relaxin family peptide receptor 3 activates extracellular signal-regulated kinase 1/2 through a protein kinase C-dependent mechanism.

van der Westhuizen ET, Werry TD, Sexton PM, Summers RJ.

Mol Pharmacol. 2007 Jun;71(6):1618-29. Epub 2007 Mar 9.

PMID:
17351017
7.

Mechanisms of ERK1/2 regulation by seven-transmembrane-domain receptors.

Werry TD, Christopoulos A, Sexton PM.

Curr Pharm Des. 2006;12(14):1683-702. Review.

PMID:
16712482
8.

Characterization of serotonin 5-HT2C receptor signaling to extracellular signal-regulated kinases 1 and 2.

Werry TD, Gregory KJ, Sexton PM, Christopoulos A.

J Neurochem. 2005 Jun;93(6):1603-15.

9.

"Ins and outs" of seven-transmembrane receptor signalling to ERK.

Werry TD, Sexton PM, Christopoulos A.

Trends Endocrinol Metab. 2005 Jan-Feb;16(1):26-33. Review.

PMID:
15620546
11.

Mechanisms of cross-talk between G-protein-coupled receptors resulting in enhanced release of intracellular Ca2+.

Werry TD, Wilkinson GF, Willars GB.

Biochem J. 2003 Sep 1;374(Pt 2):281-96. Review.

12.

Ca(2+) signalling by recombinant human CXCR2 chemokine receptors is potentiated by P2Y nucleotide receptors in HEK cells.

Werry TD, Christie MI, Dainty IA, Wilkinson GF, Willars GB.

Br J Pharmacol. 2002 Mar;135(5):1199-208.

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