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Items: 1 to 50 of 65

1.

Preclinical pharmacokinetic evaluation to facilitate repurposing of tyrosine kinase inhibitors nilotinib and imatinib as antiviral agents.

Ananthula HK, Parker S, Touchette E, Buller RM, Patel G, Kalman D, Salzer JS, Gallardo-Romero N, Olson V, Damon IK, Moir-Savitz T, Sallans L, Werner MH, Sherwin CM, Desai PB.

BMC Pharmacol Toxicol. 2018 Dec 4;19(1):80. doi: 10.1186/s40360-018-0270-x.

2.

Ethical Theories: The More, the Better?

Salloch S, Werner MH.

Am J Bioeth. 2016 Sep;16(9):40-1. doi: 10.1080/15265161.2016.1196258. No abstract available.

PMID:
27471939
3.

Natalizumab-treated patients at high risk for PML persistently excrete JC polyomavirus.

Werner MH, Huang D.

J Neurovirol. 2016 Dec;22(6):871-875. Epub 2016 May 19.

4.

Formulation approaches to improving the delivery of an antiviral drug with activity against seasonal flu.

Sammeta SM, Wang L, Mutyam SK, O'Loughlin K, Green CE, Werner MH, Kelly T, Shankar GN.

Pharm Dev Technol. 2015 Mar;20(2):169-75. doi: 10.3109/10837450.2013.852574. Epub 2013 Nov 13.

PMID:
24218989
5.

[Morality, ethics and public health: philosophy and the challenge of pluralism].

Werner MH.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2009 May;52(5):489-93. doi: 10.1007/s00103-009-0837-1. German.

PMID:
19330272
6.

Transcriptional upregulation of p21/WAF/Cip1 in myeloid leukemic blasts expressing AML1-ETO.

Berg T, Fliegauf M, Burger J, Staege MS, Liu S, Martinez N, Heidenreich O, Burdach S, Haferlach T, Werner MH, Lübbert M.

Haematologica. 2008 Nov;93(11):1728-33. doi: 10.3324/haematol.13044. Epub 2008 Sep 11.

7.

A basic/hydrophobic cleft of the T4 activator MotA interacts with the C-terminus of E.coli sigma70 to activate middle gene transcription.

Bonocora RP, Caignan G, Woodrell C, Werner MH, Hinton DM.

Mol Microbiol. 2008 Jul;69(2):331-43. doi: 10.1111/j.1365-2958.2008.06276.x.

8.

A TAF4-homology domain from the corepressor ETO is a docking platform for positive and negative regulators of transcription.

Wei Y, Liu S, Lausen J, Woodrell C, Cho S, Biris N, Kobayashi N, Wei Y, Yokoyama S, Werner MH.

Nat Struct Mol Biol. 2007 Jul;14(7):653-61. Epub 2007 Jun 17.

PMID:
17572682
9.

NIH funding: what does the future look like?

Werner MH.

Science. 2007 Apr 13;316(5822):198-200; author reply 198-200. No abstract available.

PMID:
17436447
10.

Emerging roles for the death adaptor FADD in death receptor avidity and cell cycle regulation.

Werner MH, Wu C, Walsh CM.

Cell Cycle. 2006 Oct;5(20):2332-8. Epub 2006 Oct 16. Review.

PMID:
17102623
11.
12.

The structure of FADD and its mode of interaction with procaspase-8.

Carrington PE, Sandu C, Wei Y, Hill JM, Morisawa G, Huang T, Gavathiotis E, Wei Y, Werner MH.

Mol Cell. 2006 Jun 9;22(5):599-610.

13.

FADD self-association is required for stable interaction with an activated death receptor.

Sandu C, Morisawa G, Wegorzewska I, Huang T, Arechiga AF, Hill JM, Kim T, Walsh CM, Werner MH.

Cell Death Differ. 2006 Dec;13(12):2052-61. Epub 2006 May 19.

14.

ELA2 is regulated by hematopoietic transcription factors, but not repressed by AML1-ETO.

Lausen J, Liu S, Fliegauf M, Lübbert M, Werner MH.

Oncogene. 2006 Mar 2;25(9):1349-57.

PMID:
16247445
15.

A mechanism for death receptor discrimination by death adaptors.

Sandu C, Gavathiotis E, Huang T, Wegorzewska I, Werner MH.

J Biol Chem. 2005 Sep 9;280(36):31974-80. Epub 2005 Jul 8.

16.

The nuclear receptor co-repressor (N-CoR) utilizes repression domains I and III for interaction and co-repression with ETO.

Lausen J, Cho S, Liu S, Werner MH.

J Biol Chem. 2004 Nov 19;279(47):49281-8. Epub 2004 Sep 17.

17.

T4 AsiA blocks DNA recognition by remodeling sigma70 region 4.

Lambert LJ, Wei Y, Schirf V, Demeler B, Werner MH.

EMBO J. 2004 Aug 4;23(15):2952-62. Epub 2004 Jul 15.

18.

Molecular analysis of activator engagement with RNA polymerase.

Lambert LJ, Schirf V, Demeler B, Werner MH.

Methods Enzymol. 2003;370:505-21. No abstract available.

PMID:
14712671
19.

Identification of an expanded binding surface on the FADD death domain responsible for interaction with CD95/Fas.

Hill JM, Morisawa G, Kim T, Huang T, Wei Y, Wei Y, Werner MH.

J Biol Chem. 2004 Jan 9;279(2):1474-81. Epub 2003 Oct 22.

20.

PEA-15 binding to ERK1/2 MAPKs is required for its modulation of integrin activation.

Chou FL, Hill JM, Hsieh JC, Pouyssegur J, Brunet A, Glading A, Uberall F, Ramos JW, Werner MH, Ginsberg MH.

J Biol Chem. 2003 Dec 26;278(52):52587-97. Epub 2003 Sep 23.

21.

Recognition of ERK MAP kinase by PEA-15 reveals a common docking site within the death domain and death effector domain.

Hill JM, Vaidyanathan H, Ramos JW, Ginsberg MH, Werner MH.

EMBO J. 2002 Dec 2;21(23):6494-504.

22.
23.

Flipping a genetic switch by subunit exchange.

Lambert LJ, Schirf V, Demeler B, Cadene M, Werner MH.

EMBO J. 2001 Dec 17;20(24):7149-59. Erratum in: EMBO J. 2004 Aug 4;23(15):3186.

24.

Uniform 13C/15N-labeling of DNA by tandem repeat amplification.

Werner MH, Gupta V, Lambert LJ, Nagata T.

Methods Enzymol. 2001;338:283-304.

PMID:
11460553
26.

Runt domains take the lead in hematopoiesis and osteogenesis.

Werner MH, Shigesada K, Ito Y.

Nat Med. 1999 Dec;5(12):1356-7. No abstract available.

PMID:
10581073
27.

Molecular insights into PEBP2/CBF beta-SMMHC associated acute leukemia revealed from the structure of PEBP2/CBF beta.

Goger M, Gupta V, Kim WY, Shigesada K, Ito Y, Werner MH.

Nat Struct Biol. 1999 Jul;6(7):620-3.

PMID:
10404215
28.

Immunoglobulin motif DNA recognition and heterodimerization of the PEBP2/CBF Runt domain.

Nagata T, Gupta V, Sorce D, Kim WY, Sali A, Chait BT, Shigesada K, Ito Y, Werner MH.

Nat Struct Biol. 1999 Jul;6(7):615-9.

PMID:
10404214
29.
30.

Correction of the NMR structure of the ETS1/DNA complex.

Werner MH, Clore GM, Fisher CL, Fisher RJ, Trinh L, Shiloach J, Gronenborn AM.

J Biomol NMR. 1997 Dec;10(4):317-28.

PMID:
9460239
31.

ETS1-DNA binding and intercalation: correction.

Werner MH, Gronenborn AM, Clore GM.

Science. 1997 Jun 27;276(5321):1957. No abstract available.

PMID:
9221491
32.

Architectural transcription factors: proteins that remodel DNA.

Werner MH, Burley SK.

Cell. 1997 Mar 21;88(6):733-6. Review. No abstract available.

33.

Stopping death cold.

Werner MH.

Structure. 1996 Aug 15;4(8):879-83. Review.

34.

Molecular determinants of mammmalian sex.

Werner MH, Huth JR, Gronenborn AM, Clore GM.

Trends Biochem Sci. 1996 Aug;21(8):302-8. Review.

PMID:
8772384
35.

Intercalation, DNA kinking, and the control of transcription.

Werner MH, Gronenborn AM, Clore GM.

Science. 1996 Feb 9;271(5250):778-84. Review. Erratum in: Science. 1997 Jun 27;276(5321):1957.

PMID:
8628992
36.

The solution structure of the human ETS1-DNA complex reveals a novel mode of binding and true side chain intercalation.

Werner MH, Clore M, Fisher CL, Fisher RJ, Trinh L, Shiloach J, Gronenborn AM.

Cell. 1995 Dec 1;83(5):761-71. Erratum in: Cell 1996 Oct 18;87(2):following 355.

37.

The increasing incidence of malignant gliomas and primary central nervous system lymphoma in the elderly.

Werner MH, Phuphanich S, Lyman GH.

Cancer. 1995 Nov 1;76(9):1634-42.

PMID:
8635069
38.

Neoplastic meningitis with normal neurological findings. Magnetic resonance imaging results.

Elliott P, Ku NN, Werner MH.

J Neuroimaging. 1995 Oct;5(4):233-6.

PMID:
7579752
39.

NMR spectroscopic analysis of the DNA conformation induced by the human testis determining factor SRY.

Werner MH, Bianchi ME, Gronenborn AM, Clore GM.

Biochemistry. 1995 Sep 19;34(37):11998-2004.

PMID:
7547937
40.

Increasing Incidence of Primary Brain Tumors in the Elderly in Florida.

Werner MH, Phuphanich S, Lyman GH.

Cancer Control. 1995 Jul;2(4):309-314.

PMID:
10862170
41.
42.

Activation of the sphingomyelin cycle through the low-affinity neurotrophin receptor.

Dobrowsky RT, Werner MH, Castellino AM, Chao MV, Hannun YA.

Science. 1994 Sep 9;265(5178):1596-9.

PMID:
8079174
43.
44.

Refolding proteins by gel filtration chromatography.

Werner MH, Clore GM, Gronenborn AM, Kondoh A, Fisher RJ.

FEBS Lett. 1994 May 30;345(2-3):125-30.

45.

Biphasic generation of diacylglycerol by angiotensin and phorbol ester in bovine adrenal chromaffin cells.

Tuominen RK, Werner MH, Ye H, McMillian MK, Hudson PM, Hannun YA, Hong JS.

Biochem Biophys Res Commun. 1993 Jan 15;190(1):181-5.

PMID:
8380691
48.

Multiphasic generation of diacylglycerol in thrombin-activated human platelets.

Werner MH, Bielawska AE, Hannun YA.

Biochem J. 1992 Mar 15;282 ( Pt 3):815-20.

49.

Three-dimensional structure of soybean trypsin/chymotrypsin Bowman-Birk inhibitor in solution.

Werner MH, Wemmer DE.

Biochemistry. 1992 Feb 4;31(4):999-1010.

PMID:
1734975
50.

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