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Items: 1 to 50 of 81

1.

Increased cytoplasmatic expression of cancer immune surveillance receptor CD1d in anaplastic thyroid carcinomas.

Weber F, Junger H, Werner JM, Velez Char N, Rejas C, Schlitt HJ, Hornung M.

Cancer Med. 2019 Sep 27. doi: 10.1002/cam4.2573. [Epub ahead of print]

2.

Imaging challenges of immunotherapy and targeted therapy in patients with brain metastases: Response, Progression, and Pseudoprogression.

Galldiks N, Kocher M, Ceccon G, Werner JM, Brunn A, Deckert M, Pope WB, Soffietti R, Le Rhun E, Weller M, Tonn JC, Fink GR, Langen KJ.

Neuro Oncol. 2019 Aug 22. pii: noz147. doi: 10.1093/neuonc/noz147. [Epub ahead of print]

PMID:
31437274
3.

Differentiation of treatment-related changes from tumour progression: a direct comparison between dynamic FET PET and ADC values obtained from DWI MRI.

Werner JM, Stoffels G, Lichtenstein T, Borggrefe J, Lohmann P, Ceccon G, Shah NJ, Fink GR, Langen KJ, Kabbasch C, Galldiks N.

Eur J Nucl Med Mol Imaging. 2019 Aug;46(9):1889-1901. doi: 10.1007/s00259-019-04384-7. Epub 2019 Jun 15.

PMID:
31203420
4.

Expression of CD40 Correlates Negatively with Overall and Progression-Free Survival of Low- and High-Grade Gliomas.

Werner JM, Kuhl S, Ulrich K, Krischek B, Stavrinou P, Goldbrunner R, Timmer M.

World Neurosurg. 2019 Oct;130:e17-e25. doi: 10.1016/j.wneu.2019.05.112. Epub 2019 May 21.

PMID:
31125770
5.

Death Receptor 6 (DR6) Is Overexpressed in Astrocytomas.

Stegmann S, Werner JM, Kuhl S, Röhn G, Krischek B, Stavrinou P, Goldbrunner R, Timmer M.

Anticancer Res. 2019 May;39(5):2299-2306. doi: 10.21873/anticanres.13346.

PMID:
31092421
6.

Influence of hepatic fibrosis and inflammation: Correlation between histopathological changes and Gd-EOB-DTPA-enhanced MR imaging.

Verloh N, Probst U, Utpatel K, Zeman F, Brennfleck F, Werner JM, Fellner C, Stroszczynski C, Evert M, Wiggermann P, Haimerl M.

PLoS One. 2019 May 13;14(5):e0215752. doi: 10.1371/journal.pone.0215752. eCollection 2019.

7.

Magnetic Resonance Imaging Reveals a Pronounced Treatment Response of a Isocitrate Dehydrogenase- and B-Raf Proto-Oncogene-Wildtype Epithelioid Glioblastoma.

Werner JM, Brunn A, Fink GR, Galldiks N.

World Neurosurg. 2019 Jul;127:213-215. doi: 10.1016/j.wneu.2019.04.025. Epub 2019 Apr 8.

PMID:
30974270
8.

Similar complication rates for irreversible electroporation and thermal ablation in patients with hepatocellular tumors.

Verloh N, Jensch I, Lürken L, Haimerl M, Dollinger M, Renner P, Wiggermann P, Werner JM, Zeman F, Stroszczynski C, Beyer LP.

Radiol Oncol. 2019 Mar 3;53(1):116-122. doi: 10.2478/raon-2019-0011.

9.

Successful Treatment of Myasthenia Gravis Following PD-1/CTLA-4 Combination Checkpoint Blockade in a Patient With Metastatic Melanoma.

Werner JM, Schweinsberg V, Schroeter M, von Reutern B, Malter MP, Schlaak M, Fink GR, Mauch C, Galldiks N.

Front Oncol. 2019 Feb 14;9:84. doi: 10.3389/fonc.2019.00084. eCollection 2019.

10.

Combined Amino Acid Positron Emission Tomography and Advanced Magnetic Resonance Imaging in Glioma Patients.

Lohmann P, Werner JM, Shah NJ, Fink GR, Langen KJ, Galldiks N.

Cancers (Basel). 2019 Jan 29;11(2). pii: E153. doi: 10.3390/cancers11020153. Review.

11.

Murine DX5+NKT Cells Display Their Cytotoxic and Proapoptotic Potentials against Colitis-Inducing CD4+CD62Lhigh T Cells through Fas Ligand.

Werner JM, Damian M, Farkas SA, Schlitt HJ, Geissler EK, Hornung M.

J Immunol Res. 2018 Sep 30;2018:8175810. doi: 10.1155/2018/8175810. eCollection 2018.

12.

FET PET reveals considerable spatial differences in tumour burden compared to conventional MRI in newly diagnosed glioblastoma.

Lohmann P, Stavrinou P, Lipke K, Bauer EK, Ceccon G, Werner JM, Neumaier B, Fink GR, Shah NJ, Langen KJ, Galldiks N.

Eur J Nucl Med Mol Imaging. 2019 Mar;46(3):591-602. doi: 10.1007/s00259-018-4188-8. Epub 2018 Oct 16.

PMID:
30327856
13.

Dabrafenib Treatment in a Patient with an Epithelioid Glioblastoma and BRAF V600E Mutation.

Ceccon G, Werner JM, Dunkl V, Tscherpel C, Stoffels G, Brunn A, Deckert M, Fink GR, Galldiks N.

Int J Mol Sci. 2018 Apr 5;19(4). pii: E1090. doi: 10.3390/ijms19041090.

14.

The partial dissociation of MHC class I-bound peptides exposes their N terminus to trimming by endoplasmic reticulum aminopeptidase 1.

Papakyriakou A, Reeves E, Beton M, Mikolajek H, Douglas L, Cooper G, Elliott T, Werner JM, James E.

J Biol Chem. 2018 May 18;293(20):7538-7548. doi: 10.1074/jbc.RA117.000313. Epub 2018 Mar 29.

15.

Predicting Early Viral Control under Direct-Acting Antiviral Therapy for Chronic Hepatitis C Virus Using Pretreatment Immunological Markers.

Hutchinson JA, Weigand K, Adenugba A, Kronenberg K, Haarer J, Zeman F, Riquelme P, Hornung M, Ahrens N, Schlitt HJ, Geissler EK, Werner JM.

Front Immunol. 2018 Feb 7;9:146. doi: 10.3389/fimmu.2018.00146. eCollection 2018.

16.

Expression of FAS-L Differs from Primary to Relapsed Low-grade Gliomas and Predicts Progression-free Survival.

Werner JM, Kuhl S, Stavrinou P, Röhn G, Krischek B, Blau T, Goldbrunner R, Timmer M.

Anticancer Res. 2017 Dec;37(12):6639-6648.

PMID:
29187439
17.

Direct evidence for conformational dynamics in major histocompatibility complex class I molecules.

van Hateren A, Anderson M, Bailey A, Werner JM, Skipp P, Elliott T.

J Biol Chem. 2017 Dec 8;292(49):20255-20269. doi: 10.1074/jbc.M117.809624. Epub 2017 Oct 11.

18.

Use of Immunolabeling to Analyze Stable, Dynamic, and Nascent Microtubules in the Zebrafish Embryo.

McFarland RJ, Brown SP, Vital E, Werner JM, Brewster RM.

J Vis Exp. 2017 Sep 20;(127). doi: 10.3791/55792.

19.

Discordance and Conversion Rates of Progesterone-, Estrogen-, and HER2/neu-Receptor Status in Primary Breast Cancer and Brain Metastasis Mainly Triggered by Hormone Therapy.

Timmer M, Werner JM, Röhn G, Ortmann M, Blau T, Cramer C, Stavrinou P, Krischek B, Mallman P, Goldbrunner R.

Anticancer Res. 2017 Sep;37(9):4859-4865.

PMID:
28870906
20.

Applications of hyperthermic intraperitoneal chemotherapy for metastatic colorectal cancer.

Hornung M, Werner JM, Schlitt HJ.

Expert Rev Anticancer Ther. 2017 Sep;17(9):841-850. doi: 10.1080/14737140.2017.1357470. Epub 2017 Jul 25. Review.

PMID:
28715968
21.

ALPPS (associating liver partition and portal vein ligation for staged hepatectomy) does not affect proliferation, apoptosis, or angiogenesis as compared to standard liver resection for colorectal liver metastases.

Joechle K, Moser C, Ruemmele P, Schmidt KM, Werner JM, Geissler EK, Schlitt HJ, Lang SA.

World J Surg Oncol. 2017 Mar 7;15(1):57. doi: 10.1186/s12957-017-1121-8.

22.

Immune Reconstitution After HCV Clearance With Direct Antiviral Agents: Potential Consequences for Patients With HCC?

Werner JM, Adenugba A, Protzer U.

Transplantation. 2017 May;101(5):904-909. doi: 10.1097/TP.0000000000001606. Review.

PMID:
27941432
23.

The anti-sigma factor RsrA responds to oxidative stress by reburying its hydrophobic core.

Rajasekar KV, Zdanowski K, Yan J, Hopper JT, Francis ML, Seepersad C, Sharp C, Pecqueur L, Werner JM, Robinson CV, Mohammed S, Potts JR, Kleanthous C.

Nat Commun. 2016 Jul 19;7:12194. doi: 10.1038/ncomms12194.

24.

Living Donor Liver Transplantation.

Werner JM, Schlitt HJ.

Transplantation. 2016 Jun;100(6):1173-4. doi: 10.1097/TP.0000000000001282. No abstract available.

PMID:
27203587
25.

New HCV Therapies and Liver Transplantation.

Werner JM, Vermehren J.

Transplantation. 2016 Feb;100(2):260-1. doi: 10.1097/TP.0000000000001092. Review. No abstract available.

PMID:
26813409
26.

Microtubule-associated protein 1b is required for shaping the neural tube.

Jayachandran P, Olmo VN, Sanchez SP, McFarland RJ, Vital E, Werner JM, Hong E, Sanchez-Alberola N, Molodstov A, Brewster RM.

Neural Dev. 2016 Jan 18;11:1. doi: 10.1186/s13064-015-0056-4.

27.

Selector function of MHC I molecules is determined by protein plasticity.

Bailey A, Dalchau N, Carter R, Emmott S, Phillips A, Werner JM, Elliott T.

Sci Rep. 2015 Oct 20;5:14928. doi: 10.1038/srep14928.

28.

Neuroendocrine tumors of the pancreas: a retrospective single-center analysis using the ENETS TNM-classification and immunohistochemical markers for risk stratification.

Brunner SM, Weber F, Werner JM, Agha A, Farkas SA, Schlitt HJ, Hornung M.

BMC Surg. 2015 Apr 25;15:49. doi: 10.1186/s12893-015-0033-1.

29.

Plasticity of empty major histocompatibility complex class I molecules determines peptide-selector function.

van Hateren A, Bailey A, Werner JM, Elliott T.

Mol Immunol. 2015 Dec;68(2 Pt A):98-101. doi: 10.1016/j.molimm.2015.03.010. Epub 2015 Mar 26. Review.

30.

Synthesis and evaluation of a (3R,6S,9S)-2-oxo-1-azabicyclo[4.3.0]nonane scaffold as a mimic of Xaa-trans-Pro in poly-L-proline type II helix conformation.

Aillard B, Kilburn JD, Blaydes JP, Tizzard GJ, Findlow S, Werner JM, Bloodworth S.

Org Biomol Chem. 2015 Apr 21;13(15):4562-9. doi: 10.1039/c5ob00180c.

PMID:
25777583
31.

Molecular Mechanism for the Control of Eukaryotic Elongation Factor 2 Kinase by pH: Role in Cancer Cell Survival.

Xie J, Mikolajek H, Pigott CR, Hooper KJ, Mellows T, Moore CE, Mohammed H, Werner JM, Thomas GJ, Proud CG.

Mol Cell Biol. 2015 May;35(10):1805-24. doi: 10.1128/MCB.00012-15. Epub 2015 Mar 16.

32.

X-ray, spectroscopic and normal-mode dynamics of calexcitin: structure-function studies of a neuronal calcium-signalling protein.

Erskine PT, Fokas A, Muriithi C, Rehman H, Yates LA, Bowyer A, Findlow IS, Hagan R, Werner JM, Miles AJ, Wallace BA, Wells SA, Wood SP, Cooper JB.

Acta Crystallogr D Biol Crystallogr. 2015 Mar;71(Pt 3):615-31. doi: 10.1107/S1399004714026704. Epub 2015 Feb 26.

PMID:
25760610
33.

Elongation Factor 2 Kinase Is Regulated by Proline Hydroxylation and Protects Cells during Hypoxia.

Moore CE, Mikolajek H, Regufe da Mota S, Wang X, Kenney JW, Werner JM, Proud CG.

Mol Cell Biol. 2015 May;35(10):1788-804. doi: 10.1128/MCB.01457-14. Epub 2015 Mar 9.

34.

Characterization of recombinantly expressed matrilin VWA domains.

Becker AK, Mikolajek H, Werner JM, Paulsson M, Wagener R.

Protein Expr Purif. 2015 Mar;107:20-8. doi: 10.1016/j.pep.2014.11.005. Epub 2014 Nov 21.

35.

Durability of antibody response against hepatitis B virus in healthcare workers vaccinated as adults.

Gara N, Abdalla A, Rivera E, Zhao X, Werner JM, Liang TJ, Hoofnagle JH, Rehermann B, Ghany MG.

Clin Infect Dis. 2015 Feb 15;60(4):505-13. doi: 10.1093/cid/ciu867. Epub 2014 Nov 10.

36.

Ribavirin improves the IFN-γ response of natural killer cells to IFN-based therapy of hepatitis C virus infection.

Werner JM, Serti E, Chepa-Lotrea X, Stoltzfus J, Ahlenstiel G, Noureddin M, Feld JJ, Liang TJ, Rotman Y, Rehermann B.

Hepatology. 2014 Oct;60(4):1160-9. doi: 10.1002/hep.27092. Epub 2014 Aug 13.

37.

Monocytes activate natural killer cells via inflammasome-induced interleukin 18 in response to hepatitis C virus replication.

Serti E, Werner JM, Chattergoon M, Cox AL, Lohmann V, Rehermann B.

Gastroenterology. 2014 Jul;147(1):209-220.e3. doi: 10.1053/j.gastro.2014.03.046. Epub 2014 Mar 28.

38.

Two polymorphisms facilitate differences in plasticity between two chicken major histocompatibility complex class I proteins.

Bailey A, van Hateren A, Elliott T, Werner JM.

PLoS One. 2014 Feb 20;9(2):e89657. doi: 10.1371/journal.pone.0089657. eCollection 2014.

39.

A structure of a collagen VI VWA domain displays N and C termini at opposite sides of the protein.

Becker AK, Mikolajek H, Paulsson M, Wagener R, Werner JM.

Structure. 2014 Feb 4;22(2):199-208. doi: 10.1016/j.str.2013.06.028. Epub 2013 Dec 12.

40.

The hepatitis B vaccine protects re-exposed health care workers, but does not provide sterilizing immunity.

Werner JM, Abdalla A, Gara N, Ghany MG, Rehermann B.

Gastroenterology. 2013 Nov;145(5):1026-34. doi: 10.1053/j.gastro.2013.07.044. Epub 2013 Jul 31.

41.

Occupational exposure to hepatitis C virus: early T-cell responses in the absence of seroconversion in a longitudinal cohort study.

Heller T, Werner JM, Rahman F, Mizukoshi E, Sobao Y, Gordon AM, Sheets A, Sherker AH, Kessler E, Bean KS, Herrine SK, Stevens M, Schmitt J, Rehermann B.

J Infect Dis. 2013 Sep;208(6):1020-5. doi: 10.1093/infdis/jit270. Epub 2013 Jun 24.

42.

Innate immune responses in hepatitis C virus-exposed healthcare workers who do not develop acute infection.

Werner JM, Heller T, Gordon AM, Sheets A, Sherker AH, Kessler E, Bean KS, Stevens M, Schmitt J, Rehermann B.

Hepatology. 2013 Nov;58(5):1621-31. doi: 10.1002/hep.26353. Epub 2013 Sep 30.

43.

2β-deoxy-Kdo is an inhibitor of the Arabidopsis thaliana CMP-2-Keto-3-deoxymanno-octulosonic acid synthetase, the enzyme required for activation of Kdo prior to incorporation into rhamnogalacturonan II.

Smyth KM, Mikolajek H, Werner JM, Marchant A.

Mol Plant. 2013 May;6(3):981-4. doi: 10.1093/mp/sst011. Epub 2013 Jan 18. No abstract available.

44.

Morphological differences between β(2) -microglobulin in fibrils and inclusion bodies.

Taylor GF, Wood SP, Mörs K, Glaubitz C, Werner JM, Williamson PT.

Chembiochem. 2011 Mar 7;12(4):556-8. doi: 10.1002/cbic.201000582. Epub 2011 Jan 26.

45.

Insights into the regulation of eukaryotic elongation factor 2 kinase and the interplay between its domains.

Pigott CR, Mikolajek H, Moore CE, Finn SJ, Phippen CW, Werner JM, Proud CG.

Biochem J. 2012 Feb 15;442(1):105-18. doi: 10.1042/BJ20111536.

46.

Predictors of computer use in community-dwelling, ethnically diverse older adults.

Werner JM, Carlson M, Jordan-Marsh M, Clark F.

Hum Factors. 2011 Oct;53(5):431-47.

47.

A peptide filtering relation quantifies MHC class I peptide optimization.

Dalchau N, Phillips A, Goldstein LD, Howarth M, Cardelli L, Emmott S, Elliott T, Werner JM.

PLoS Comput Biol. 2011 Oct;7(10):e1002144. doi: 10.1371/journal.pcbi.1002144. Epub 2011 Oct 13.

48.

Migration and chemokine receptor pattern of colitis-preventing DX5+NKT cells.

Hornung M, Werner JM, Farkas S, Schlitt HJ, Geissler EK.

Int J Colorectal Dis. 2011 Nov;26(11):1423-33. doi: 10.1007/s00384-011-1249-x. Epub 2011 Jun 7.

PMID:
21647599
49.

Distribution of intrahepatic T, NK and CD3(+)CD56(+)NKT cells alters after liver transplantation: Shift from innate to adaptive immunity?

Werner JM, Lang C, Scherer MN, Farkas SA, Geissler EK, Schlitt HJ, Hornung M.

Transpl Immunol. 2011 Jul;25(1):27-33. doi: 10.1016/j.trim.2011.05.006. Epub 2011 May 23.

PMID:
21635950
50.

DX5+NKT cells display phenotypical and functional differences between spleen and liver as well as NK1.1-Balb/c and NK1.1+ C57Bl/6 mice.

Werner JM, Busl E, Farkas SA, Schlitt HJ, Geissler EK, Hornung M.

BMC Immunol. 2011 Apr 29;12:26. doi: 10.1186/1471-2172-12-26.

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