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Emergence delirium in children is related to epileptiform discharges during anaesthesia induction: An observational study.

Koch S, Rupp L, Prager C, Wernecke KD, Kramer S, Fahlenkamp A, Spies CD.

Eur J Anaesthesiol. 2018 Aug 14. doi: 10.1097/EJA.0000000000000867. [Epub ahead of print]


Predator odour but not TMT induces 22-kHz ultrasonic vocalizations in rats that lead to defensive behaviours in conspecifics upon replay.

Fendt M, Brosch M, Wernecke KEA, Willadsen M, Wöhr M.

Sci Rep. 2018 Jul 23;8(1):11041. doi: 10.1038/s41598-018-28927-4.


Incidence of epileptiform discharges in children during induction of anaesthesia using Propofol versus Sevoflurane.

Koch S, Rupp L, Prager C, Mörgeli R, Kramer S, Wernecke KD, Fahlenkamp A, Spies C.

Clin Neurophysiol. 2018 Aug;129(8):1642-1648. doi: 10.1016/j.clinph.2018.05.013. Epub 2018 Jun 8.


Predator odor induced defensive behavior in wild and laboratory rats: A comparative study.

Storsberg S, Stryjek R, Modlińska K, Gottswinter K, D'Hanis W, Kröber A, Wernecke KEA, Roskoden T, Fendt M.

Physiol Behav. 2018 Oct 1;194:341-347. doi: 10.1016/j.physbeh.2018.06.009. Epub 2018 Jun 9.


Patient Empowerment Reduces Pain in Geriatric Patients After Gynecologic Onco-Surgery: Subgroup Analysis of a Prospective Randomized Controlled Clinical Trial.

Collette AM, Spies C, Eckardt R, Wernecke KD, Schmidt M; PERATECS Group.

J Perianesth Nurs. 2018 Jun;33(3):281-289. doi: 10.1016/j.jopan.2016.10.005. Epub 2017 Apr 5.


Reversal of apixaban induced alterations in haemostasis by different coagulation factor concentrates in patients after hip or knee replacement surgery.

Schmidt K, Krüger K, Langer E, Schmutzler M, Johnen E, Wernecke KD, Von Heymann C, Körber MK.

Blood Transfus. 2018 May 11:1-6. doi: 10.2450/2018.0028-18. [Epub ahead of print]


Balanced 10% hydroxyethyl starch compared with balanced 6% hydroxyethyl starch and balanced crystalloid using a goal-directed hemodynamic algorithm in pancreatic surgery: A randomized clinical trial.

Werner J, Hunsicker O, Schneider A, Stein H, von Heymann C, Freitag A, Feldheiser A, Wernecke KD, Spies C.

Medicine (Baltimore). 2018 Apr;97(17):e0579. doi: 10.1097/MD.0000000000010579.


Long-term sequelae of acute respiratory distress syndrome caused by severe community-acquired pneumonia: Delirium-associated cognitive impairment and post-traumatic stress disorder.

Denke C, Balzer F, Menk M, Szur S, Brosinsky G, Tafelski S, Wernecke KD, Deja M.

J Int Med Res. 2018 Jun;46(6):2265-2283. doi: 10.1177/0300060518762040. Epub 2018 Apr 2.


Nucleated red blood cells as predictors of mortality in patients with acute respiratory distress syndrome (ARDS): an observational study.

Menk M, Giebelhäuser L, Vorderwülbecke G, Gassner M, Graw JA, Weiss B, Zimmermann M, Wernecke KD, Weber-Carstens S.

Ann Intensive Care. 2018 Mar 27;8(1):42. doi: 10.1186/s13613-018-0387-5.


Associations of postoperative mortality with the time of day, week and year.

Kork F, Spies C, Conrad T, Weiss B, Roenneberg T, Wernecke KD, Balzer F.

Anaesthesia. 2018 Jun;73(6):711-718. doi: 10.1111/anae.14228. Epub 2018 Feb 23.


Risk factors for 30-day complications after cancer surgery in geriatric patients: a secondary analysis.

Scholtz K, Spies CD, Mörgeli R, Eckardt R, von Dossow V, Braun S, Sehouli J, Bahra M, Stief CG, Wernecke KD, Schmidt M; PERATECS Group.

Acta Anaesthesiol Scand. 2018 Apr;62(4):451-463. doi: 10.1111/aas.13067. Epub 2018 Jan 22.


The new agreement of the international RIGA consensus conference on nasal airway function tests.

Vogt K, Bachmann-Harildstad G, Lintermann A, Nechyporenko A, Peters F, Wernecke KD.

Rhinology. 2018 Jun 1;56(2):133-143. doi: 10.4193/Rhin17.084.


Ethanol-Induced Alterations of T Cells and Cytokines after Surgery in a Murine Infection Model.

Lanzke N, Menk M, von Haefen C, Sargsyan L, Scharf B, Wernecke KD, Spies CD.

Int J Inflam. 2017;2017:1067598. doi: 10.1155/2017/1067598. Epub 2017 Nov 20.


Readiness to change and therapy outcomes of an innovative psychotherapy program for surgical patients: results from a randomized controlled trial.

Krampe H, Salz AL, Kerper LF, Krannich A, Schnell T, Wernecke KD, Spies CD.

BMC Psychiatry. 2017 Dec 29;17(1):417. doi: 10.1186/s12888-017-1579-5.


Smoking, Gender, and Overweight Are Important Influencing Factors on Monocytic HLA-DR before and after Major Cancer Surgery.

Lachmann G, von Haefen C, Kurth J, Yuerek F, Wernecke KD, Spies C.

Biomed Res Int. 2017;2017:5216562. doi: 10.1155/2017/5216562. Epub 2017 Aug 8.


The growth of uterine myomas in untreated women: influence factors and ultrasound monitoring.

Armbrust R, Wernecke KD, Sehouli J, David M.

Arch Gynecol Obstet. 2018 Jan;297(1):131-137. doi: 10.1007/s00404-017-4568-5. Epub 2017 Oct 23.


Fears and Concerns of Patients with Uterine Fibroids - a Survey of 807 Women.

Knudsen NI, Wernecke KD, Siedentopf F, David M.

Geburtshilfe Frauenheilkd. 2017 Sep;77(9):976-983. doi: 10.1055/s-0043-118132. Epub 2017 Sep 25.


Diagnostic value of plasma NGAL and intraoperative diuresis for AKI after major gynecological surgery in patients treated within an intraoperative goal-directed hemodynamic algorithm: A substudy of a randomized controlled trial.

Hunsicker O, Feldheiser A, Weimann A, Liehre D, Sehouli J, Wernecke KD, Spies C.

Medicine (Baltimore). 2017 Jul;96(28):e7357. doi: 10.1097/MD.0000000000007357.


In vivo application of Granulocyte-Macrophage Colony-stimulating Factor enhances postoperative qualitative monocytic function.

Lachmann G, Kurth J, von Haefen C, Yuerek F, Wernecke KD, Spies C.

Int J Med Sci. 2017 Apr 8;14(4):367-375. doi: 10.7150/ijms.18288. eCollection 2017.


Habenula and interpeduncular nucleus differentially modulate predator odor-induced innate fear behavior in rats.

Vincenz D, Wernecke KEA, Fendt M, Goldschmidt J.

Behav Brain Res. 2017 Aug 14;332:164-171. doi: 10.1016/j.bbr.2017.05.053. Epub 2017 May 26.


Tea-induced improvement of endothelial function in humans: No role for epigallocatechin gallate (EGCG).

Lorenz M, Rauhut F, Hofer C, Gwosc S, Müller E, Praeger D, Zimmermann BF, Wernecke KD, Baumann G, Stangl K, Stangl V.

Sci Rep. 2017 May 23;7(1):2279. doi: 10.1038/s41598-017-02384-x.


In vitro and ex vivo Measurement of Prophylactic Dabigatran Concentrations with a New Ecarin-Based Thromboelastometry Test.

Körber MK, Langer E, Köhr M, Wernecke KD, Korte W, von Heymann C.

Transfus Med Hemother. 2017 Apr;44(2):100-105. doi: 10.1159/000470622. Epub 2017 Mar 27.


Whole-body vibration to prevent intensive care unit-acquired weakness: safety, feasibility, and metabolic response.

Wollersheim T, Haas K, Wolf S, Mai K, Spies C, Steinhagen-Thiessen E, Wernecke KD, Spranger J, Weber-Carstens S.

Crit Care. 2017 Jan 9;21(1):9. doi: 10.1186/s13054-016-1576-y.


Influence of Volatile Anesthesia on the Release of Glutamate and other Amino Acids in the Nucleus Accumbens in a Rat Model of Alcohol Withdrawal: A Pilot Study.

Seidemann T, Spies C, Morgenstern R, Wernecke KD, Netzhammer N.

PLoS One. 2017 Jan 3;12(1):e0169017. doi: 10.1371/journal.pone.0169017. eCollection 2017.


Observational clinical study on organ dysfunction associated with dosing of antibiotics in a Pediatric Intensive Care Unit.

Tafelski S, Gratopp A, Richter F, Kramer S, Spies C, Wernecke KD, Nachtigall I.

Minerva Pediatr. 2018 Aug;70(4):331-339. doi: 10.23736/S0026-4946.16.04667-3. Epub 2016 Nov 10.


Predictors of survival in critically ill patients with acute respiratory distress syndrome (ARDS): an observational study.

Balzer F, Menk M, Ziegler J, Pille C, Wernecke KD, Spies C, Schmidt M, Weber-Carstens S, Deja M.

BMC Anesthesiol. 2016 Nov 8;16(1):108.


Influence of female sex and fertile age on neuromyelitis optica spectrum disorders.

Borisow N, Kleiter I, Gahlen A, Fischer K, Wernecke KD, Pache F, Ruprecht K, Havla J, Krumbholz M, Kümpfel T, Aktas O, Ringelstein M, Geis C, Kleinschnitz C, Berthele A, Hemmer B, Angstwurm K, Weissert R, Stellmann JP, Schuster S, Stangel M, Lauda F, Tumani H, Mayer C, Zeltner L, Ziemann U, Linker RA, Schwab M, Marziniak M, Then Bergh F, Hofstadt-van Oy U, Neuhaus O, Winkelmann A, Marouf W, Rückriem L, Faiss J, Wildemann B, Paul F, Jarius S, Trebst C, Hellwig K; NEMOS (Neuromyelitis Optica Study Group).

Mult Scler. 2017 Jul;23(8):1092-1103. doi: 10.1177/1352458516671203. Epub 2016 Oct 6.


Does the severity of preoperative anemia or blood transfusion have a stronger impact on long-term survival after cardiac surgery?

von Heymann C, Kaufner L, Sander M, Spies C, Schmidt K, Gombotz H, Wernecke KD, Balzer F.

J Thorac Cardiovasc Surg. 2016 Nov;152(5):1412-1420. doi: 10.1016/j.jtcvs.2016.06.010. Epub 2016 Jun 22.


Validity of Different Delirium Assessment Tools for Critically Ill Children: Covariates Matter.

Luetz A, Gensel D, Müller J, Weiss B, Martiny V, Heinz A, Wernecke KD, Spies C.

Crit Care Med. 2016 Nov;44(11):2060-2069.


Effects of repetitive imagination of alcohol consumption on craving in alcohol-dependent patients: A pilot study.

Geisel O, Behnke J, Schneider M, Wernecke KD, Müller CA.

Addict Behav Rep. 2016 Aug 7;4:51-57. doi: 10.1016/j.abrep.2016.08.001. eCollection 2016 Dec.


Routine delirium monitoring is independently associated with a reduction of hospital mortality in critically ill surgical patients: A prospective, observational cohort study.

Luetz A, Weiss B, Boettcher S, Burmeister J, Wernecke KD, Spies C.

J Crit Care. 2016 Oct;35:168-73. doi: 10.1016/j.jcrc.2016.05.028. Epub 2016 Jun 7.


Feasibility of noise reduction by a modification in ICU environment.

Luetz A, Weiss B, Penzel T, Fietze I, Glos M, Wernecke KD, Bluemke B, Dehn AM, Willemeit T, Finke A, Spies C.

Physiol Meas. 2016 Jul;37(7):1041-55. doi: 10.1088/0967-3334/37/7/1041. Epub 2016 May 31.


Impact of retained blood requiring reintervention on outcomes after cardiac surgery.

Balzer F, von Heymann C, Boyle EM, Wernecke KD, Grubitzsch H, Sander M.

J Thorac Cardiovasc Surg. 2016 Aug;152(2):595-601.e4. doi: 10.1016/j.jtcvs.2016.03.086. Epub 2016 Apr 14.


Correction: Perioperative Care and the Importance of Continuous Quality Improvement-A Controlled Intervention Study in Three Tanzanian Hospitals.

Bosse G, Abels W, Mtatifikolo F, Ngoli B, Neuner B, Wernecke KD, Spies C.

PLoS One. 2016 May 19;11(5):e0156206. doi: 10.1371/journal.pone.0156206. eCollection 2016.


End-of-life decisions in surgical intensive care medicine - the relevance of blood transfusions.

Graw JA, Spies CD, Wernecke KD, Braun JP.

Transfus Apher Sci. 2016 Jun;54(3):416-20. doi: 10.1016/j.transci.2016.03.005. Epub 2016 Mar 24.


Impact of preoperative 18F-FDG PET/CT on survival of resected mono-metastatic non-small cell lung cancer.

Tönnies S, Tönnies M, Kollmeier J, Bauer TT, Förster GJ, Kaiser D, Wernecke KD, Pfannschmidt J.

Lung Cancer. 2016 Mar;93:28-34. doi: 10.1016/j.lungcan.2015.12.008. Epub 2015 Dec 30.


Poor Sleep in Multiple Sclerosis Correlates with Beck Depression Inventory Values, but Not with Polysomnographic Data.

Veauthier C, Gaede G, Radbruch H, Wernecke KD, Paul F.

Sleep Disord. 2016;2016:8378423. doi: 10.1155/2016/8378423. Epub 2016 Jan 18.


Influence of Granulocyte-Macrophage Colony-Stimulating Factor or Influenza Vaccination on HLA-DR, Infection and Delirium Days in Immunosuppressed Surgical Patients: Double Blind, Randomised Controlled Trial.

Spies C, Luetz A, Lachmann G, Renius M, von Haefen C, Wernecke KD, Bahra M, Schiemann A, Paupers M, Meisel C.

PLoS One. 2015 Dec 7;10(12):e0144003. doi: 10.1371/journal.pone.0144003. eCollection 2015.


Predator odor exposure increases food-carrying behavior in rats.

Wernecke KE, Brüggemann J, Fendt M.

Physiol Behav. 2016 Feb 1;154:15-9. doi: 10.1016/j.physbeh.2015.11.005. Epub 2015 Nov 7.


Neuromyelitis optica: Evaluation of 871 attacks and 1,153 treatment courses.

Kleiter I, Gahlen A, Borisow N, Fischer K, Wernecke KD, Wegner B, Hellwig K, Pache F, Ruprecht K, Havla J, Krumbholz M, Kümpfel T, Aktas O, Hartung HP, Ringelstein M, Geis C, Kleinschnitz C, Berthele A, Hemmer B, Angstwurm K, Stellmann JP, Schuster S, Stangel M, Lauda F, Tumani H, Mayer C, Zeltner L, Ziemann U, Linker R, Schwab M, Marziniak M, Then Bergh F, Hofstadt-van Oy U, Neuhaus O, Winkelmann A, Marouf W, Faiss J, Wildemann B, Paul F, Jarius S, Trebst C; Neuromyelitis Optica Study Group.

Ann Neurol. 2016 Feb;79(2):206-16. doi: 10.1002/ana.24554. Epub 2015 Nov 26.


Minor Postoperative Increases of Creatinine Are Associated with Higher Mortality and Longer Hospital Length of Stay in Surgical Patients.

Kork F, Balzer F, Spies CD, Wernecke KD, Ginde AA, Jankowski J, Eltzschig HK.

Anesthesiology. 2015 Dec;123(6):1301-11. doi: 10.1097/ALN.0000000000000891.


Periodic limb movements during REM sleep in multiple sclerosis: a previously undescribed entity.

Veauthier C, Gaede G, Radbruch H, Sieb JP, Wernecke KD, Paul F.

Neuropsychiatr Dis Treat. 2015 Sep 9;11:2323-9. doi: 10.2147/NDT.S83350. eCollection 2015.


Peripheral intravenous cannulation with support of infrared laser vein viewing system in a pre-operation setting in pediatric patients.

Rothbart A, Yu P, Müller-Lobeck L, Spies CD, Wernecke KD, Nachtigall I.

BMC Res Notes. 2015 Sep 21;8:463. doi: 10.1186/s13104-015-1431-2.


The olfactory hole-board test in rats: a new paradigm to study aversion and preferences to odors.

Wernecke KE, Fendt M.

Front Behav Neurosci. 2015 Aug 25;9:223. doi: 10.3389/fnbeh.2015.00223. eCollection 2015.


Patient Empowerment Improved Perioperative Quality of Care in Cancer Patients Aged ≥ 65 Years - A Randomized Controlled Trial.

Schmidt M, Eckardt R, Scholtz K, Neuner B, von Dossow-Hanfstingl V, Sehouli J, Stief CG, Wernecke KD, Spies CD; PERATECS Group.

PLoS One. 2015 Sep 17;10(9):e0137824. doi: 10.1371/journal.pone.0137824. eCollection 2015.


Perioperative Care and the Importance of Continuous Quality Improvement--A Controlled Intervention Study in Three Tanzanian Hospitals.

Bosse G, Abels W, Mtatifikolo F, Ngoli B, Neuner B, Wernecke KD, Spies C.

PLoS One. 2015 Sep 1;10(9):e0136156. doi: 10.1371/journal.pone.0136156. eCollection 2015. Erratum in: PLoS One. 2016;11(5):e0156206.


Dynamic muscle O2 saturation response is impaired during major non-cardiac surgery despite goal-directed haemodynamic therapy.

Feldheiser A, Hunsicker O, Kaufner L, Köhler J, Sieglitz H, Casans Francés R, Wernecke KD, Sehouli J, Spies C.

Rev Esp Anestesiol Reanim. 2016 Mar;63(3):149-58. doi: 10.1016/j.redar.2015.06.011. Epub 2015 Aug 28. English, Spanish.


[Commentary: "The So-Called 'Ocular Pressure Flow Analyzer (OPFA)' Gives a Measure of the Extensibility of the Eye Wall"].

Ulrich WD, Moeller A, Ulrich C, Siebert G, Wernecke KD, Erb C.

Klin Monbl Augenheilkd. 2015 Aug;232(8):1001-2. doi: 10.1055/s-0035-1546043. Epub 2015 Aug 19. German. No abstract available.


A Rare Case of Isolated Cerebral Sarcoidosis Presenting as Suprasellar Mass Lesion with Salt-Wasting Hypopituitarism.

Krenzlin H, Jussen D, Musahl C, Scheil-Bertram S, Wernecke K, Horn P.

J Neurol Surg Rep. 2015 Jul;76(1):e140-5. doi: 10.1055/s-0035-1549310. Epub 2015 Apr 27.

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