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Items: 1 to 50 of 403

1.

European task force on atopic dermatitis position paper: treatment of parental atopic dermatitis during preconception, pregnancy and lactation period.

Vestergaard C, Wollenberg A, Barbarot S, Christen-Zaech S, Deleuran M, Spuls P, Flohr C, Trzeciak M, von Kobyletzki L, Seneschal J, Paul C, Bieber T, Werfel T, Fölster-Holst R, Darsow U, Gieler U, Svensson Å, Cork M, Stalder JF, De Raeve L, Kunz B, Simon D, Chernyshov P, Hijnen D, Gelmetti C, Ring J, Taieb A, de Bruin-Weller M, Thyssen JP.

J Eur Acad Dermatol Venereol. 2019 Jun 23. doi: 10.1111/jdv.15709. [Epub ahead of print]

PMID:
31231864
2.

Pathomechanism of Dupilumab-associated inflammatory eye symptoms.

Wohlrab J, Werfel T, Wollenberg A.

J Eur Acad Dermatol Venereol. 2019 Jun 20. doi: 10.1111/jdv.15755. [Epub ahead of print]

PMID:
31220376
3.

[A "hot" topic: skin diseases and the microbiome].

Werfel T, Gläser R.

Hautarzt. 2019 Jun;70(6):398-399. doi: 10.1007/s00105-019-4422-8. German. No abstract available.

PMID:
31165215
4.

Highlights in allergic contact dermatitis 2018/2019.

Johansen JD, Werfel T.

Curr Opin Allergy Clin Immunol. 2019 May 27. doi: 10.1097/ACI.0000000000000552. [Epub ahead of print]

PMID:
31145193
5.

Preparation of Neutrally-charged, pH-responsive Polymeric Nanoparticles for Cytosolic siRNA Delivery.

Hendershot J, Smith AE, Werfel TA.

J Vis Exp. 2019 May 2;(147). doi: 10.3791/59549.

PMID:
31107463
6.

[47-year-old female with excoriated papules and erythematous partly lichenified areas on the trunk and arms : Preparation for the specialist examination: part 53].

Maghsudi H, Werfel T.

Hautarzt. 2019 Apr;70(Suppl 1):100-102. doi: 10.1007/s00105-019-4374-z. German. No abstract available.

PMID:
30976872
7.

The roadmap for the Allergology specialty and allergy care in Europe and adjacent countries. An EAACI position paper.

Fyhrquist N, Werfel T, Bilò MB, Mülleneisen N, Gerth van Wijk R.

Clin Transl Allergy. 2019 Jan 24;9:3. doi: 10.1186/s13601-019-0245-z. eCollection 2019. Review.

8.

Gal8 Visualization of Endosome Disruption Predicts Carrier-Mediated Biologic Drug Intracellular Bioavailability.

Kilchrist KV, Dimobi SC, Jackson MA, Evans BC, Werfel TA, Dailing EA, Bedingfield SK, Kelly IB, Duvall CL.

ACS Nano. 2019 Feb 26;13(2):1136-1152. doi: 10.1021/acsnano.8b05482. Epub 2019 Jan 18.

PMID:
30629431
9.

Stimulation of histamine H4 receptors increases the production of IL-9 in Th9 polarized cells.

Schaper-Gerhardt K, Wohlert M, Mommert S, Kietzmann M, Werfel T, Gutzmer R.

Br J Pharmacol. 2018 Dec 27. doi: 10.1111/bph.14566. [Epub ahead of print]

PMID:
30589077
10.

[Interdisciplinary recommendations for action in dupilumab-related inflammatory eye diseases].

Wohlrab J, Wollenberg A, Reimann H, Pleyer U, Werfel T.

Hautarzt. 2019 Jan;70(1):64-67. doi: 10.1007/s00105-018-4316-1. German. No abstract available.

PMID:
30478601
11.

The role of the histamine H4 receptor in atopic dermatitis and psoriasis.

Schaper-Gerhardt K, Rossbach K, Nikolouli E, Werfel T, Gutzmer R, Mommert S.

Br J Pharmacol. 2018 Nov 21. doi: 10.1111/bph.14550. [Epub ahead of print] Review.

PMID:
30460986
12.

Efficacy and safety of the histamine H4 receptor antagonist ZPL-3893787 in patients with atopic dermatitis.

Werfel T, Layton G, Yeadon M, Whitlock L, Osterloh I, Jimenez P, Liu W, Lynch V, Asher A, Tsianakas A, Purkins L.

J Allergy Clin Immunol. 2019 May;143(5):1830-1837.e4. doi: 10.1016/j.jaci.2018.07.047. Epub 2018 Nov 9.

PMID:
30414855
13.

Human and computational models of atopic dermatitis: A review and perspectives by an expert panel of the International Eczema Council.

Eyerich K, Brown SJ, Perez White BE, Tanaka RJ, Bissonette R, Dhar S, Bieber T, Hijnen DJ, Guttman-Yassky E, Irvine A, Thyssen JP, Vestergaard C, Werfel T, Wollenberg A, Paller AS, Reynolds NJ.

J Allergy Clin Immunol. 2019 Jan;143(1):36-45. doi: 10.1016/j.jaci.2018.10.033. Epub 2018 Nov 7.

14.

Treatment-Induced Tumor Cell Apoptosis and Secondary Necrosis Drive Tumor Progression in the Residual Tumor Microenvironment through MerTK and IDO1.

Werfel TA, Elion DL, Rahman B, Hicks DJ, Sanchez V, Gonzales-Ericsson PI, Nixon MJ, James JL, Balko JM, Scherle PA, Koblish HK, Cook RS.

Cancer Res. 2019 Jan 1;79(1):171-182. doi: 10.1158/0008-5472.CAN-18-1106. Epub 2018 Nov 9.

PMID:
30413412
15.

Non-celiac gluten/wheat sensitivity (NCGS)-a currently undefined disorder without validated diagnostic criteria and of unknown prevalence: Position statement of the task force on food allergy of the German Society of Allergology and Clinical Immunology (DGAKI).

Reese I, Schäfer C, Kleine-Tebbe J, Ahrens B, Bachmann O, Ballmer-Weber B, Beyer K, Bischoff SC, Blümchen K, Dölle S, Enck P, Enninger A, Huttegger I, Lämmel S, Lange L, Lepp U, Mahler V, Mönnikes H, Ockenga J, Otto B, Schnadt S, Szepfalusi Z, Treudler R, Wassmann-Otto A, Zuberbier T, Werfel T, Worm M.

Allergo J Int. 2018;27(5):147-151. doi: 10.1007/s40629-018-0070-2. Epub 2018 May 28.

16.

[Decreased professional performance and quality of life in patients with moderate-to-severe atopic eczema : Results from the German atopic eczema registry TREATgermany].

Haufe E, Abraham S, Heratizadeh A, Harder I, Zink A, Weisshaar E, Kleinheinz A, von Kiedrowski R, Worm M, Bell M, Wollenberg A, Neubert K, Staubach-Renz P, Hilgers M, Bieber T, Fell I, Homey B, Effendy I, Mempel M, Schäkel K, Beissert S, Weidinger S, Werfel T, Schmitt J.

Hautarzt. 2018 Oct;69(10):815-824. doi: 10.1007/s00105-018-4261-z. German.

PMID:
30191254
17.

Efferocytosis in the tumor microenvironment.

Werfel TA, Cook RS.

Semin Immunopathol. 2018 Nov;40(6):545-554. doi: 10.1007/s00281-018-0698-5. Epub 2018 Sep 5. Review.

18.

Novel systemic drugs in treatment of atopic dermatitis: results from phase II and phase III studies published in 2017/2018.

Werfel T.

Curr Opin Allergy Clin Immunol. 2018 Oct;18(5):432-437. doi: 10.1097/ACI.0000000000000477. Review.

PMID:
30095475
19.

The Anaphylatoxin C3a Receptor Expression on Human M2 Macrophages Is Down-Regulated by Stimulating the Histamine H4 Receptor and the IL-4 Receptor.

Mommert S, Aslan D, Ratz L, Stark H, Gutzmer R, Werfel T.

J Innate Immun. 2018;10(4):349-362. doi: 10.1159/000490426. Epub 2018 Jul 20.

20.

Molecular Regulation of Acute Tie2 Suppression in Sepsis.

Thamm K, Schrimpf C, Retzlaff J, Idowu TO, van Meurs M, Zijlstra JG, Ghosh CC, Zeitvogel J, Werfel TA, Haller H, Parikh SM, David S.

Crit Care Med. 2018 Sep;46(9):e928-e936. doi: 10.1097/CCM.0000000000003269.

PMID:
29979219
21.

Consensus-based European guidelines for treatment of atopic eczema (atopic dermatitis) in adults and children: part II.

Wollenberg A, Barbarot S, Bieber T, Christen-Zaech S, Deleuran M, Fink-Wagner A, Gieler U, Girolomoni G, Lau S, Muraro A, Czarnecka-Operacz M, Schäfer T, Schmid-Grendelmeier P, Simon D, Szalai Z, Szepietowski JC, Taïeb A, Torrelo A, Werfel T, Ring J; European Dermatology Forum (EDF), the European Academy of Dermatology and Venereology (EADV), the European Academy of Allergy and Clinical Immunology (EAACI), the European Task Force on Atopic Dermatitis (ETFAD), European Federation of Allergy and Airways Diseases Patients’ Associations (EFA), the European Society for Dermatology and Psychiatry (ESDaP), the European Society of Pediatric Dermatology (ESPD), Global Allergy and Asthma European Network (GA2LEN) and the European Union of Medical Specialists (UEMS).

J Eur Acad Dermatol Venereol. 2018 Jun;32(6):850-878. doi: 10.1111/jdv.14888.

PMID:
29878606
22.

Contact Allergy: A Review of Current Problems from a Clinical Perspective.

Uter W, Werfel T, White IR, Johansen JD.

Int J Environ Res Public Health. 2018 May 29;15(6). pii: E1108. doi: 10.3390/ijerph15061108. Review.

23.

Measurement of healthcare quality in atopic dermatitis - development and application of a set of quality indicators.

Steinke S, Beikert FC, Langenbruch A, Fölster-Holst R, Ring J, Schmitt J, Werfel T, Hintzen S, Franzke N, Augustin M.

J Eur Acad Dermatol Venereol. 2018 Dec;32(12):2237-2243. doi: 10.1111/jdv.15074. Epub 2018 Jun 13.

PMID:
29763514
24.

Consensus-based European guidelines for treatment of atopic eczema (atopic dermatitis) in adults and children: part I.

Wollenberg A, Barbarot S, Bieber T, Christen-Zaech S, Deleuran M, Fink-Wagner A, Gieler U, Girolomoni G, Lau S, Muraro A, Czarnecka-Operacz M, Schäfer T, Schmid-Grendelmeier P, Simon D, Szalai Z, Szepietowski JC, Taïeb A, Torrelo A, Werfel T, Ring J; European Dermatology Forum (EDF), the European Academy of Dermatology and Venereology (EADV), the European Academy of Allergy and Clinical Immunology (EAACI), the European Task Force on Atopic Dermatitis (ETFAD), European Federation of Allergy and Airways Diseases Patients’ Associations (EFA), the European Society for Dermatology and Psychiatry (ESDaP), the European Society of Pediatric Dermatology (ESPD), Global Allergy and Asthma European Network (GA2LEN) and the European Union of Medical Specialists (UEMS).

J Eur Acad Dermatol Venereol. 2018 May;32(5):657-682. doi: 10.1111/jdv.14891.

PMID:
29676534
25.

Birch pollen-related foods can cause late eczematous reactions in patients with atopic dermatitis.

Wassmann-Otto A, Heratizadeh A, Wichmann K, Werfel T.

Allergy. 2018 Oct;73(10):2046-2054. doi: 10.1111/all.13454. Epub 2018 Oct 2.

PMID:
29654628
26.

The histamine H4 receptor modulates the differentiation process of human monocyte-derived M1 macrophages and the release of CCL4/MIP-1β from fully differentiated M1 macrophages.

Mommert S, Ratz L, Stark H, Gutzmer R, Werfel T.

Inflamm Res. 2018 Jun;67(6):503-513. doi: 10.1007/s00011-018-1140-0. Epub 2018 Mar 29.

PMID:
29600327
27.

Impact of increasing treatment rates on cost-effectiveness of subcutaneous immunotherapy (SCIT) in respiratory allergy: a decision analytic modelling approach.

Richter AK, Klimek L, Merk HF, Mülleneisen N, Renz H, Wehrmann W, Werfel T, Hamelmann E, Siebert U, Sroczynski G, Wasem J, Biermann-Stallwitz J.

Eur J Health Econ. 2018 Dec;19(9):1229-1242. doi: 10.1007/s10198-018-0970-6. Epub 2018 Mar 24.

PMID:
29574666
28.

Recurrent erysipelas of the face with hyperimmune reaction to group C streptococcus.

Dequidt L, Jullie ML, Seneschal J, Werfel T, Taïeb A.

Br J Dermatol. 2018 Aug;179(2):524-525. doi: 10.1111/bjd.16538. Epub 2018 May 29. No abstract available.

PMID:
29526042
29.

[Topical therapy for atopic eczema].

Knop M, Gürtler A, Heratizadeh A, Aszodi N, Werfel T, Wollenberg A.

Hautarzt. 2018 Mar;69(3):210-216. doi: 10.1007/s00105-018-4135-4. Review. German.

PMID:
29487960
30.

[New aspects in systemic treatment of atopic dermatitis].

Werfel T, Wollenberg A, Pumnea T, Heratizadeh A.

Hautarzt. 2018 Mar;69(3):217-224. doi: 10.1007/s00105-018-4131-8. Review. German.

PMID:
29470609
31.

[Patient education for adults with atopic dermatitis according to the ARNE concept].

Heratizadeh A, Werfel T, Gieler U, Kupfer J; Arbeitsgemeinschaft Neurodermitisschulung für Erwachsene (ARNE).

Hautarzt. 2018 Mar;69(3):225-231. doi: 10.1007/s00105-018-4125-6. German.

PMID:
29445852
32.

Selective mTORC2 Inhibitor Therapeutically Blocks Breast Cancer Cell Growth and Survival.

Werfel TA, Wang S, Jackson MA, Kavanaugh TE, Joly MM, Lee LH, Hicks DJ, Sanchez V, Ericsson PG, Kilchrist KV, Dimobi SC, Sarett SM, Brantley-Sieders DM, Cook RS, Duvall CL.

Cancer Res. 2018 Apr 1;78(7):1845-1858. doi: 10.1158/0008-5472.CAN-17-2388. Epub 2018 Jan 22.

33.

Intrinsic apoptotic pathway activation increases response to anti-estrogens in luminal breast cancers.

Williams MM, Lee L, Werfel T, Joly MMM, Hicks DJ, Rahman B, Elion D, McKernan C, Sanchez V, Estrada MV, Massarweh S, Elledge R, Duvall C, Cook RS.

Cell Death Dis. 2018 Jan 17;9(2):21. doi: 10.1038/s41419-017-0072-x.

34.

Contact sensitization in dental technicians with occupational contact dermatitis. Data of the Information Network of Departments of Dermatology (IVDK) 2001-2015.

Heratizadeh A, Werfel T, Schubert S, Geier J; IVDK.

Contact Dermatitis. 2018 Apr;78(4):266-273. doi: 10.1111/cod.12943. Epub 2018 Jan 12.

PMID:
29327359
35.

[Important information regarding the guideline for (allergen-)specific immunotherapy (SIT)].

Klimek L, Werfel T.

Hautarzt. 2018 Jan;69(1):84-85. doi: 10.1007/s00105-017-4093-2. German. No abstract available.

PMID:
29242961
36.

RNase 7 Strongly Promotes TLR9-Mediated DNA Sensing by Human Plasmacytoid Dendritic Cells.

Kopfnagel V, Wagenknecht S, Harder J, Hofmann K, Kleine M, Buch A, Sodeik B, Werfel T.

J Invest Dermatol. 2018 Apr;138(4):872-881. doi: 10.1016/j.jid.2017.09.052. Epub 2017 Nov 20.

37.

Patients with atopic dermatitis and history of eczema herpeticum elicit herpes simplex virus-specific type 2 immune responses.

Traidl S, Kienlin P, Begemann G, Jing L, Koelle DM, Werfel T, Roesner LM.

J Allergy Clin Immunol. 2018 Mar;141(3):1144-1147.e5. doi: 10.1016/j.jaci.2017.09.048. Epub 2017 Nov 16. No abstract available.

PMID:
29155096
38.

Course of respiratory allergy by treatment strategy based on German routine data.

Weschenfelder AK, Klimek L, Mülleneisen N, Renz H, Wehrmann W, Werfel T, Hamelmann E, Wasem J, Biermann J.

Allergo J Int. 2017;26(6):195-203. doi: 10.1007/s40629-017-0027-x. Epub 2017 May 30.

39.

GATA3 regulates FLG and FLG2 expression in human primary keratinocytes.

Zeitvogel J, Jokmin N, Rieker S, Klug I, Brandenberger C, Werfel T.

Sci Rep. 2017 Sep 19;7(1):11847. doi: 10.1038/s41598-017-10252-x.

40.

Lipophilic siRNA targets albumin in situ and promotes bioavailability, tumor penetration, and carrier-free gene silencing.

Sarett SM, Werfel TA, Lee L, Jackson MA, Kilchrist KV, Brantley-Sieders D, Duvall CL.

Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):E6490-E6497. doi: 10.1073/pnas.1621240114. Epub 2017 Jul 24.

41.

Histamine H2 receptor stimulation upregulates TH2 chemokine CCL17 production in human M2a macrophages.

Mommert S, Gregor K, Rossbach K, Schaper K, Witte T, Gutzmer R, Werfel T.

J Allergy Clin Immunol. 2018 Feb;141(2):782-785.e5. doi: 10.1016/j.jaci.2017.06.023. Epub 2017 Jul 18. No abstract available.

PMID:
28728999
42.

Skin allergy.

Zuberbier T, Werfel T.

Curr Opin Allergy Clin Immunol. 2017 Aug;17(4):262. doi: 10.1097/ACI.0000000000000383. No abstract available.

PMID:
28622170
43.

Zwitterionic Nanocarrier Surface Chemistry Improves siRNA Tumor Delivery and Silencing Activity Relative to Polyethylene Glycol.

Jackson MA, Werfel TA, Curvino EJ, Yu F, Kavanaugh TE, Sarett SM, Dockery MD, Kilchrist KV, Jackson AN, Giorgio TD, Duvall CL.

ACS Nano. 2017 Jun 27;11(6):5680-5696. doi: 10.1021/acsnano.7b01110. Epub 2017 Jun 7.

44.

Inflammatory marker analysis in psoriatic skin under topical phosphodiesterase 4 inhibitor treatment.

Roesner LM, Kienlin P, Begemann G, Dittrich-Breiholz O, Werfel T.

J Allergy Clin Immunol. 2017 Oct;140(4):1184-1187.e8. doi: 10.1016/j.jaci.2017.04.026. Epub 2017 May 12. No abstract available.

PMID:
28506848
45.

Combined treatment with H1 and H4 receptor antagonists reduces inflammation in a mouse model of atopic dermatitis.

Köchling H, Schaper K, Wilzopolski J, Gutzmer R, Werfel T, Bäumer W, Kietzmann M, Rossbach K.

J Dermatol Sci. 2017 Aug;87(2):130-137. doi: 10.1016/j.jdermsci.2017.04.004. Epub 2017 Apr 21.

PMID:
28495120
46.

An open, multicentre, randomized clinical study in patients with bullous pemphigoid comparing methylprednisolone and azathioprine with methylprednisolone and dapsone.

Sticherling M, Franke A, Aberer E, Gläser R, Hertl M, Pfeiffer C, Rzany B, Schneider S, Shimanovich I, Werfel T, Wilczek A, Zillikens D, Schmidt E.

Br J Dermatol. 2017 Nov;177(5):1299-1305. doi: 10.1111/bjd.15649. Epub 2017 Oct 29.

PMID:
28494097
47.

In-vitro diagnostic in atopic dermatitis: Options and limitations.

Wichmann K, Heratizadeh A, Werfel T.

Allergol Select. 2017 Apr 7;1(2):150-159. doi: 10.5414/ALX01549E. eCollection 2017. Review.

48.

RNase 7 downregulates TH2 cytokine production by activated human T cells.

Kopfnagel V, Wagenknecht S, Brand L, Zeitvogel J, Harder J, Hofmann K, Kleine M, Werfel T.

Allergy. 2017 Nov;72(11):1694-1703. doi: 10.1111/all.13173. Epub 2017 Jun 21.

PMID:
28378334
49.

Combinatorial optimization of PEG architecture and hydrophobic content improves ternary siRNA polyplex stability, pharmacokinetics, and potency in vivo.

Werfel TA, Jackson MA, Kavanaugh TE, Kirkbride KC, Miteva M, Giorgio TD, Duvall C.

J Control Release. 2017 Jun 10;255:12-26. doi: 10.1016/j.jconrel.2017.03.389. Epub 2017 Mar 31.

50.

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