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Items: 1 to 50 of 273

1.

Development and Initial Validation of the Asthma Severity Scoring System (ASSESS).

Fitzpatrick AM, Szefler SJ, Mauger DT, Phillips BR, Denlinger LC, Moore WC, Sorkness RL, Wenzel SE, Gergen PJ, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Israel E, Levy BD, Meyers DA, Teague WG, Bacharier LB, Ly NP, Phipatanakul W, Ross KR, Zein J, Jarjour NN.

J Allergy Clin Immunol. 2019 Oct 8. pii: S0091-6749(19)31254-0. doi: 10.1016/j.jaci.2019.09.018. [Epub ahead of print]

PMID:
31604088
2.

Dupilumab Efficacy in Patients With Uncontrolled, Moderate-to-Severe Allergic Asthma.

Corren J, Castro M, O'Riordan T, Hanania NA, Pavord ID, Quirce S, Chipps BE, Wenzel SE, Thangavelu K, Rice MS, Harel S, Jagerschmidt A, Khan A, Kamat S, Maroni J, Rowe P, Lu Y, Amin N, Pirozzi G, Ruddy M, Graham NMH, Teper A.

J Allergy Clin Immunol Pract. 2019 Sep 12. pii: S2213-2198(19)30775-5. doi: 10.1016/j.jaip.2019.08.050. [Epub ahead of print]

3.

Estimated Ventricular Size, Asthma Severity and Exacerbations: The SARP III Cohort.

Ash SY, Vegas Sanchez-Ferrero G, Schiebler ML, Rahaghi FN, Rai A, Come CE, Ross JC, Colon AG, Cardet JC, Bleecker ER, Castro M, Fahy JV, Fain SB, Gaston BM, Hoffman EA, Jarjour NN, Lempel JK, Mauger DT, Tattersall MC, Wenzel SE, Levy BD, Washko GR, Israel E, San Jose Estepar R; SARP Investigators.

Chest. 2019 Sep 12. pii: S0012-3692(19)33744-4. doi: 10.1016/j.chest.2019.08.2185. [Epub ahead of print]

PMID:
31521672
4.

Investigation of the relationship between IL-6 and type 2 biomarkers in patients with severe asthma.

Li X, Hastie AT, Peters MC, Hawkins GA, Phipatanakul W, Li H, Moore WC, Busse WW, Castro M, Erzurum SC, Gaston B, Israel E, Jarjour NN, Levy BD, Wenzel SE, Meyers DA, Fahy JV, Bleecker ER; National Heart, Lung, and Blood Institute's Severe Asthma Research Program (SARP) Networks.

J Allergy Clin Immunol. 2019 Sep 9. pii: S0091-6749(19)31173-X. doi: 10.1016/j.jaci.2019.08.031. [Epub ahead of print] No abstract available.

PMID:
31513878
5.

As-needed β agonist-inhaled corticosteroid in mild asthma.

Gauthier M, Wenzel SE.

Lancet. 2019 Sep 14;394(10202):897-898. doi: 10.1016/S0140-6736(19)31994-4. Epub 2019 Aug 23. No abstract available.

PMID:
31451208
6.

Clinical significance of the bronchodilator response in children with severe asthma.

Coverstone AM, Bacharier LB, Wilson BS, Fitzpatrick AM, Teague WG, Phipatanakul W, Wenzel SE, Gaston BM, Bleecker ER, Moore WC, Ramratnam S, Jarjour NN, Ly NP, Fahy JV, Mauger DT, Schechtman KB, Yin-DeClue H, Boomer JS, Castro M.

Pediatr Pulmonol. 2019 Nov;54(11):1694-1703. doi: 10.1002/ppul.24473. Epub 2019 Aug 19.

PMID:
31424170
7.

15-Lipoxygenase 1 in nasal polyps promotes CCL26/eotaxin 3 expression through extracellular signal-regulated kinase activation.

Li Z, Zeng M, Deng Y, Zhao J, Zhou X, Trudeau JB, Goldschmidt E, Moore JA, Chu H, Zhang W, Yin S, Liu Z, Di YP, Lee SE, Wenzel SE.

J Allergy Clin Immunol. 2019 Jul 11. pii: S0091-6749(19)30905-4. doi: 10.1016/j.jaci.2019.06.037. [Epub ahead of print]

PMID:
31301373
8.

Structural and Functional Features on Quantitative Chest Computed Tomography in the Korean Asian versus the White American Healthy Non-Smokers.

Cho HB, Chae KJ, Jin GY, Choi J, Lin CL, Hoffman EA, Wenzel SE, Castro M, Fain SB, Jarjour NN, Schiebler ML, Barr RG, Hansel N, Cooper CB, Kleerup EC, Han MK, Woodruff PG, Kanner RE, Bleecker ER, Peters SP, Moore WC, Lee CH, Choi S; National Heart, Lung and Blood Institute's SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS) and Severe Asthma Research Program (SARP).

Korean J Radiol. 2019 Jul;20(7):1236-1245. doi: 10.3348/kjr.2019.0083.

9.

BAL Cell Gene Expression in Severe Asthma Reveals Mechanisms of Severe Disease and Influences of Medications.

Weathington N, O'Brien ME, Radder J, Whisenant TC, Bleecker ER, Busse WW, Erzurum SC, Gaston B, Hastie AT, Jarjour NN, Meyers DA, Milosevic J, Moore WC, Tedrow JR, Trudeau JB, Wong HP, Wu W, Kaminski N, Wenzel SE, Modena BD.

Am J Respir Crit Care Med. 2019 Oct 1;200(7):837-856. doi: 10.1164/rccm.201811-2221OC.

PMID:
31161938
10.

Redox (phospho)lipidomics of signaling in inflammation and programmed cell death.

Tyurina YY, St Croix CM, Watkins SC, Watson AM, Epperly MW, Anthonymuthu TS, Kisin ER, Vlasova II, Krysko O, Krysko DV, Kapralov AA, Dar HH, Tyurin VA, Amoscato AA, Popova EN, Bolevich SB, Timashev PS, Kellum JA, Wenzel SE, Mallampalli RK, Greenberger JS, Bayir H, Shvedova AA, Kagan VE.

J Leukoc Biol. 2019 Jul;106(1):57-81. doi: 10.1002/JLB.3MIR0119-004RR. Epub 2019 May 9. Review.

11.

The effect of BPIFA1/SPLUNC1 genetic variation on its expression and function in asthmatic airway epithelium.

Schaefer N, Li X, Seibold MA, Jarjour NN, Denlinger LC, Castro M, Coverstone AM, Teague WG, Boomer J, Bleecker ER, Meyers DA, Moore WC, Hawkins GA, Fahy J, Phillips BR, Mauger DT, Dakhama A, Gellatly S, Pavelka N, Berman R, Di YP, Wenzel SE, Chu HW.

JCI Insight. 2019 Apr 18;4(8). pii: 127237. doi: 10.1172/jci.insight.127237. eCollection 2019 Apr 18.

12.

Extracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma.

Lachowicz-Scroggins ME, Dunican EM, Charbit AR, Raymond W, Looney MR, Peters MC, Gordon ED, Woodruff PG, Lefrançais E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, Coverstone AM, Castro M, Hastie AT, Bleecker ER, Fajt ML, Wenzel SE, Israel E, Levy BD, Fahy JV.

Am J Respir Crit Care Med. 2019 May 1;199(9):1076-1085. doi: 10.1164/rccm.201810-1869OC.

PMID:
30888839
13.

Differences in Particle Deposition Between Members of Imaging-Based Asthma Clusters.

Choi J, LeBlanc LJ, Choi S, Haghighi B, Hoffman EA, O'Shaughnessy P, Wenzel SE, Castro M, Fain S, Jarjour N, Schiebler ML, Denlinger L, Delvadia R, Walenga R, Babiskin A, Lin CL.

J Aerosol Med Pulm Drug Deliv. 2019 Aug;32(4):213-223. doi: 10.1089/jamp.2018.1487. Epub 2019 Mar 19.

PMID:
30888242
14.

Solving insomnia electronically: Sleep treatment for asthma (SIESTA): A study protocol for a randomized controlled trial.

Shi X, Buysse DJ, Ritterband LM, Sereika SM, Strollo PJ, Wenzel SE, Luyster FS.

Contemp Clin Trials. 2019 Apr;79:73-79. doi: 10.1016/j.cct.2019.02.011. Epub 2019 Feb 27.

PMID:
30825525
15.

Characterization of Differential Dynamics, Specificity, and Allostery of Lipoxygenase Family Members.

Mikulska-Ruminska K, Shrivastava I, Krieger J, Zhang S, Li H, Bayır H, Wenzel SE, VanDemark AP, Kagan VE, Bahar I.

J Chem Inf Model. 2019 May 28;59(5):2496-2508. doi: 10.1021/acs.jcim.9b00006. Epub 2019 Feb 28.

16.

Sialylation of MUC4β N-glycans by ST6GAL1 orchestrates human airway epithelial cell differentiation associated with type-2 inflammation.

Zhou X, Kinlough CL, Hughey RP, Jin M, Inoue H, Etling E, Modena BD, Kaminski N, Bleecker ER, Meyers DA, Jarjour NN, Trudeau JB, Holguin F, Ray A, Wenzel SE.

JCI Insight. 2019 Mar 7;4(5). pii: 122475. doi: 10.1172/jci.insight.122475. eCollection 2019 Mar 7.

17.

Multiview Cluster Analysis Identifies Variable Corticosteroid Response Phenotypes in Severe Asthma.

Wu W, Bang S, Bleecker ER, Castro M, Denlinger L, Erzurum SC, Fahy JV, Fitzpatrick AM, Gaston BM, Hastie AT, Israel E, Jarjour NN, Levy BD, Mauger DT, Meyers DA, Moore WC, Peters M, Phillips BR, Phipatanakul W, Sorkness RL, Wenzel SE.

Am J Respir Crit Care Med. 2019 Jun 1;199(11):1358-1367. doi: 10.1164/rccm.201808-1543OC. Erratum in: Am J Respir Crit Care Med. 2019 Aug 1;200(3):400.

PMID:
30682261
18.

Dysfunctional ErbB2, an EGF receptor family member, hinders repair of airway epithelial cells from asthmatic patients.

Inoue H, Hattori T, Zhou X, Etling EB, Modena BD, Trudeau JB, Holguin F, Wenzel SE.

J Allergy Clin Immunol. 2019 Jun;143(6):2075-2085.e10. doi: 10.1016/j.jaci.2018.11.046. Epub 2019 Jan 10.

19.

Racial disparities in asthma-related health care use in the National Heart, Lung, and Blood Institute's Severe Asthma Research Program.

Fitzpatrick AM, Gillespie SE, Mauger DT, Phillips BR, Bleecker ER, Israel E, Meyers DA, Moore WC, Sorkness RL, Wenzel SE, Bacharier LB, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston BM, Jarjour NN, Larkin A, Levy BD, Ly NP, Ortega VE, Peters SP, Phipatanakul W, Ramratnam S, Teague WG.

J Allergy Clin Immunol. 2019 Jun;143(6):2052-2061. doi: 10.1016/j.jaci.2018.11.022. Epub 2019 Jan 8.

PMID:
30635198
20.

Adapting clinical trial design to maintain meaningful outcomes during a multicenter asthma trial in the precision medicine era.

Sorkness CA, King TS, Dyer AM, Chinchilli VM, Mauger DT, Krishnan JA, Blake K, Castro M, Covar R, Israel E, Kraft M, Lang JE, Lugogo N, Peters SP, Wechsler ME, Wenzel SE, Lazarus SC; National Heart Lung and Blood Institute's “AsthmaNet”.

Contemp Clin Trials. 2019 Feb;77:98-103. doi: 10.1016/j.cct.2018.12.012. Epub 2018 Dec 27.

PMID:
30593883
21.

Clinical Issues in Severe Asthma: Debates and Discussions About Personalizing Patient Management.

Panettieri RA Jr, Wechsler ME, Wenzel SE.

Chest. 2018 Dec;154(6):1459-1460. doi: 10.1016/j.chest.2018.09.002.

PMID:
30526975
22.

Empowerment of 15-Lipoxygenase Catalytic Competence in Selective Oxidation of Membrane ETE-PE to Ferroptotic Death Signals, HpETE-PE.

Anthonymuthu TS, Kenny EM, Shrivastava I, Tyurina YY, Hier ZE, Ting HC, Dar HH, Tyurin VA, Nesterova A, Amoscato AA, Mikulska-Ruminska K, Rosenbaum JC, Mao G, Zhao J, Conrad M, Kellum JA, Wenzel SE, VanDemark AP, Bahar I, Kagan VE, Bayır H.

J Am Chem Soc. 2018 Dec 26;140(51):17835-17839. doi: 10.1021/jacs.8b09913. Epub 2018 Dec 17.

PMID:
30525572
23.

Clinical Issues in Severe Asthma: Consensus and Controversies on the Road to Precision Medicine.

Bleecker ER, Panettieri RA Jr, Wenzel SE.

Chest. 2018 Oct;154(4):982-983. doi: 10.1016/j.chest.2018.08.1022.

PMID:
30290932
24.

Internet-Based Cognitive-Behavioral Therapy for Insomnia in Adults With Asthma: A Pilot Study.

Luyster FS, Ritterband LM, Sereika SM, Buysse DJ, Wenzel SE, Strollo PJ.

Behav Sleep Med. 2018 Sep 25:1-13. doi: 10.1080/15402002.2018.1518229. [Epub ahead of print]

PMID:
30252506
25.

Association of free vitamin D3 concentrations and asthma treatment failures in the VIDA Trial.

Lima JJ, Castro M, King TS, Lang JE, Ortega VE, Peters SP, Denlinger LC, Israel E, Sorkness CA, Wechsler ME, Wenzel SE, Smith LJ.

Ann Allergy Asthma Immunol. 2018 Oct;121(4):444-450.e1. doi: 10.1016/j.anai.2018.06.001. Epub 2018 Jun 14.

26.

Prospective predictors of exacerbation status in severe asthma over a 3-year follow-up.

Kimura H, Konno S, Makita H, Taniguchi N, Shimizu K, Suzuki M, Kimura H, Goudarzi H, Nakamaru Y, Ono J, Ohta S, Izuhara K, Ito YM, Wenzel SE, Nishimura M; Hi-CARAT investigators.

Clin Exp Allergy. 2018 Sep;48(9):1137-1146. doi: 10.1111/cea.13170. Epub 2018 Jun 4.

PMID:
29781543
27.

Liberty Asthma QUEST: Phase 3 Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate Dupilumab Efficacy/Safety in Patients with Uncontrolled, Moderate-to-Severe Asthma.

Busse WW, Maspero JF, Rabe KF, Papi A, Wenzel SE, Ford LB, Pavord ID, Zhang B, Staudinger H, Pirozzi G, Amin N, Akinlade B, Eckert L, Chao J, Graham NMH, Teper A.

Adv Ther. 2018 May;35(5):737-748. doi: 10.1007/s12325-018-0702-4. Epub 2018 May 3.

28.

Pruning of the Pulmonary Vasculature in Asthma. The Severe Asthma Research Program (SARP) Cohort.

Ash SY, Rahaghi FN, Come CE, Ross JC, Colon AG, Cardet-Guisasola JC, Dunican EM, Bleecker ER, Castro M, Fahy JV, Fain SB, Gaston BM, Hoffman EA, Jarjour NN, Mauger DT, Wenzel SE, Levy BD, San Jose Estepar R, Israel E, Washko GR; SARP Investigators.

Am J Respir Crit Care Med. 2018 Jul 1;198(1):39-50. doi: 10.1164/rccm.201712-2426OC.

29.

Effects of endogenous sex hormones on lung function and symptom control in adolescents with asthma.

DeBoer MD, Phillips BR, Mauger DT, Zein J, Erzurum SC, Fitzpatrick AM, Gaston BM, Myers R, Ross KR, Chmiel J, Lee MJ, Fahy JV, Peters M, Ly NP, Wenzel SE, Fajt ML, Holguin F, Moore WC, Peters SP, Meyers D, Bleecker ER, Castro M, Coverstone AM, Bacharier LB, Jarjour NN, Sorkness RL, Ramratnam S, Irani AM, Israel E, Levy B, Phipatanakul W, Gaffin JM, Gerald Teague W.

BMC Pulm Med. 2018 Apr 10;18(1):58. doi: 10.1186/s12890-018-0612-x.

30.

ALX receptor ligands define a biochemical endotype for severe asthma.

Ricklefs I, Barkas I, Duvall MG, Cernadas M, Grossman NL, Israel E, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Denlinger LC, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, Hastie AT, Johansson MW, Peters MC, Phillips BR, Levy BD; National Heart Lung and Blood Institute’s Severe Asthma Research Program- Investigators.

JCI Insight. 2018 Mar 22;3(6). pii: 120932. doi: 10.1172/jci.insight.120932. No abstract available.

31.

Refractory airway type 2 inflammation in a large subgroup of asthmatic patients treated with inhaled corticosteroids.

Peters MC, Kerr S, Dunican EM, Woodruff PG, Fajt ML, Levy BD, Israel E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, Coverstone AM, Castro M, Hastie AT, Bleecker ER, Wenzel SE, Fahy JV; National Heart, Lung and Blood Institute Severe Asthma Research Program 3.

J Allergy Clin Immunol. 2019 Jan;143(1):104-113.e14. doi: 10.1016/j.jaci.2017.12.1009. Epub 2018 Mar 7.

PMID:
29524537
32.

Differentiation of quantitative CT imaging phenotypes in asthma versus COPD.

Choi S, Haghighi B, Choi J, Hoffman EA, Comellas AP, Newell JD, Wenzel SE, Castro M, Fain SB, Jarjour NN, Schiebler ML, Barr RG, Han MK, Bleecker ER, Cooper CB, Couper D, Hansel N, Kanner RE, Kazerooni EA, Kleerup EAC, Martinez FJ, O'Neal WK, Woodruff PG, Lin CL.

BMJ Open Respir Res. 2017 Nov 9;4(1):e000252. doi: 10.1136/bmjresp-2017-000252. eCollection 2017. Erratum in: BMJ Open Respir Res. 2018 Mar 6;5(1):e000252corr1.

33.

Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction.

Dunican EM, Elicker BM, Gierada DS, Nagle SK, Schiebler ML, Newell JD, Raymond WW, Lachowicz-Scroggins ME, Di Maio S, Hoffman EA, Castro M, Fain SB, Jarjour NN, Israel E, Levy BD, Erzurum SC, Wenzel SE, Meyers DA, Bleecker ER, Phillips BR, Mauger DT, Gordon ED, Woodruff PG, Peters MC, Fahy JV; National Heart Lung and Blood Institute (NHLBI) Severe Asthma Research Program (SARP).

J Clin Invest. 2018 Mar 1;128(3):997-1009. doi: 10.1172/JCI95693. Epub 2018 Feb 5.

34.

ATP12A promotes mucus dysfunction during Type 2 airway inflammation.

Lennox AT, Coburn SL, Leech JA, Heidrich EM, Kleyman TR, Wenzel SE, Pilewski JM, Corcoran TE, Myerburg MM.

Sci Rep. 2018 Feb 1;8(1):2109. doi: 10.1038/s41598-018-20444-8.

35.

Crosstalk between mAChRM3 and β2AR, via acetylcholine PI3/PKC/PBEP1/Raf-1 MEK1/2/ERK1/2 pathway activation, in human bronchial epithelial cells after long-term cigarette smoke exposure.

Albano GD, Bonanno A, Moscato M, Anzalone G, Di Sano C, Riccobono L, Wenzel SE, Profita M.

Life Sci. 2018 Jan 1;192:99-109. doi: 10.1016/j.lfs.2017.11.034. Epub 2017 Nov 22.

PMID:
29175450
36.

Association of interleukin 1 receptor-like 1 gene polymorphisms with eosinophilic phenotype in Japanese adults with asthma.

Inoue H, Ito I, Niimi A, Matsumoto H, Oguma T, Tajiri T, Iwata T, Nagasaki T, Kanemitsu Y, Morishima T, Hirota T, Tamari M, Wenzel SE, Mishima M.

Respir Investig. 2017 Nov;55(6):338-347. doi: 10.1016/j.resinv.2017.08.006. Epub 2017 Sep 22.

PMID:
29153414
37.

Aerosol deposition predictions in computed tomography-derived skeletons from severe asthmatics: A feasibility study.

Miyawaki S, Hoffman EA, Wenzel SE, Lin CL.

Clin Biomech (Bristol, Avon). 2019 Jun;66:81-87. doi: 10.1016/j.clinbiomech.2017.10.020. Epub 2017 Nov 4.

PMID:
29129332
38.

Peripheral Eosinophilia in Patients With Inflammatory Bowel Disease Defines an Aggressive Disease Phenotype.

Click B, Anderson AM, Koutroubakis IE, Rivers CR, Babichenko D, Machicado JD, Hartman DJ, Hashash JG, Dunn MA, Schwartz M, Swoger J, Barrie A III, Wenzel SE, Regueiro M, Binion DG.

Am J Gastroenterol. 2017 Dec;112(12):1849-1858. doi: 10.1038/ajg.2017.402. Epub 2017 Nov 7.

PMID:
29112200
39.

Internet-Based Monitoring in the Severe Asthma Research Program Identifies a Subgroup of Patients With Labile Asthma Control.

Wong-McGrath K, Denlinger LC, Bleecker ER, Castro M, Gaston B, Israel E, Jarjour NN, Mauger DT, Peters S, Phillips BR, Wenzel SE, Fahy JV, Peters MC; National Heart Lung and Blood Institute’s Severe Asthma Research Program-3 Investigators.

Chest. 2018 Feb;153(2):378-386. doi: 10.1016/j.chest.2017.10.017. Epub 2017 Oct 26.

40.

PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals.

Wenzel SE, Tyurina YY, Zhao J, St Croix CM, Dar HH, Mao G, Tyurin VA, Anthonymuthu TS, Kapralov AA, Amoscato AA, Mikulska-Ruminska K, Shrivastava IH, Kenny EM, Yang Q, Rosenbaum JC, Sparvero LJ, Emlet DR, Wen X, Minami Y, Qu F, Watkins SC, Holman TR, VanDemark AP, Kellum JA, Bahar I, Bayır H, Kagan VE.

Cell. 2017 Oct 19;171(3):628-641.e26. doi: 10.1016/j.cell.2017.09.044.

41.

An invisible disease: severe asthma is more than just "bad asthma".

Wenzel SE, Brillhart S, Nowack K.

Eur Respir J. 2017 Sep 20;50(3). pii: 1701109. doi: 10.1183/13993003.01109-2017. Print 2017 Sep. No abstract available.

42.

Distinct Phenotypes of Smokers with Fixed Airflow Limitation Identified by Cluster Analysis of Severe Asthma.

Konno S, Taniguchi N, Makita H, Nakamaru Y, Shimizu K, Shijubo N, Fuke S, Takeyabu K, Oguri M, Kimura H, Maeda Y, Suzuki M, Nagai K, Ito YM, Wenzel SE, Nishimura M; HiCARAT Investigators ‡; HiCARAT Investigators.

Ann Am Thorac Soc. 2018 Jan;15(1):33-41. doi: 10.1513/AnnalsATS.201701-065OC.

43.

Baseline Features of the Severe Asthma Research Program (SARP III) Cohort: Differences with Age.

Teague WG, Phillips BR, Fahy JV, Wenzel SE, Fitzpatrick AM, Moore WC, Hastie AT, Bleecker ER, Meyers DA, Peters SP, Castro M, Coverstone AM, Bacharier LB, Ly NP, Peters MC, Denlinger LC, Ramratnam S, Sorkness RL, Gaston BM, Erzurum SC, Comhair SAA, Myers RE, Zein J, DeBoer MD, Irani AM, Israel E, Levy B, Cardet JC, Phipatanakul W, Gaffin JM, Holguin F, Fajt ML, Aujla SJ, Mauger DT, Jarjour NN.

J Allergy Clin Immunol Pract. 2018 Mar - Apr;6(2):545-554.e4. doi: 10.1016/j.jaip.2017.05.032. Epub 2017 Aug 31.

44.

"Only a Life Lived for Others Is Worth Living": Redox Signaling by Oxygenated Phospholipids in Cell Fate Decisions.

Tyurina YY, Shrivastava I, Tyurin VA, Mao G, Dar HH, Watkins S, Epperly M, Bahar I, Shvedova AA, Pitt B, Wenzel SE, Mallampalli RK, Sadovsky Y, Gabrilovich D, Greenberger JS, Bayır H, Kagan VE.

Antioxid Redox Signal. 2018 Nov 1;29(13):1333-1358. doi: 10.1089/ars.2017.7124. Epub 2017 Oct 16. Review.

PMID:
28835115
45.

Natural killer cell-mediated inflammation resolution is disabled in severe asthma.

Duvall MG, Barnig C, Cernadas M, Ricklefs I, Krishnamoorthy N, Grossman NL, Bhakta NR, Fahy JV, Bleecker ER, Castro M, Erzurum SC, Gaston BM, Jarjour NN, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, Hastie AT, Johansson MW, Peters MC, Phillips BR, Israel E, Levy BD; National Heart, Lung, and Blood Institute’s Severe Asthma Research Program-3 Investigators.

Sci Immunol. 2017 Mar 10;2(9). pii: eaam5446. doi: 10.1126/sciimmunol.aam5446.

46.

Expression of intelectin-1 in bronchial epithelial cells of asthma is correlated with T-helper 2 (Type-2) related parameters and its function.

Watanabe T, Chibana K, Shiobara T, Tei R, Koike R, Nakamura Y, Arai R, Horigane Y, Shimizu Y, Takemasa A, Fukuda T, Wenzel SE, Ishii Y.

Allergy Asthma Clin Immunol. 2017 Aug 1;13:35. doi: 10.1186/s13223-017-0207-8. eCollection 2017.

47.

ALX receptor ligands define a biochemical endotype for severe asthma.

Ricklefs I, Barkas I, Duvall MG, Cernadas M, Grossman NL, Israel E, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Denlinger LC, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, Hastie AT, Johansson MW, Peters MC, Phillips BR, Levy BD; National Heart Lung and Blood Institute’s Severe Asthma Research Program-3 Investigators.

JCI Insight. 2017 Jul 20;2(14). pii: 93534. doi: 10.1172/jci.insight.93534. eCollection 2017 Jul 20. Erratum in: JCI Insight. 2018 Mar 22;3(6):.

48.

Severe asthma in humans and mouse model suggests a CXCL10 signature underlies corticosteroid-resistant Th1 bias.

Gauthier M, Chakraborty K, Oriss TB, Raundhal M, Das S, Chen J, Huff R, Sinha A, Fajt M, Ray P, Wenzel SE, Ray A.

JCI Insight. 2017 Jul 6;2(13). pii: 94580. doi: 10.1172/jci.insight.94580. eCollection 2017 Jul 6.

49.

American Thoracic Society/National Heart, Lung, and Blood Institute Asthma-Chronic Obstructive Pulmonary Disease Overlap Workshop Report.

Woodruff PG, van den Berge M, Boucher RC, Brightling C, Burchard EG, Christenson SA, Han MK, Holtzman MJ, Kraft M, Lynch DA, Martinez FD, Reddel HK, Sin DD, Washko GR, Wenzel SE, Punturieri A, Freemer MM, Wise RA.

Am J Respir Crit Care Med. 2017 Aug 1;196(3):375-381. doi: 10.1164/rccm.201705-0973WS.

50.

IRF5 distinguishes severe asthma in humans and drives Th1 phenotype and airway hyperreactivity in mice.

Oriss TB, Raundhal M, Morse C, Huff RE, Das S, Hannum R, Gauthier MC, Scholl KL, Chakraborty K, Nouraie SM, Wenzel SE, Ray P, Ray A.

JCI Insight. 2017 May 18;2(10). pii: 91019. doi: 10.1172/jci.insight.91019. eCollection 2017 May 18.

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