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Items: 1 to 50 of 259

1.

Characterization of differential dynamics, specificity, and allostery of lipoxygenase family members.

Mikulska-Ruminska K, Shrivastava IH, Krieger J, Zhang S, Li H, Bayir H, Wenzel SE, VanDemark AP, Kagan VE, Bahar I.

J Chem Inf Model. 2019 Feb 14. doi: 10.1021/acs.jcim.9b00006. [Epub ahead of print]

PMID:
30762363
2.

Sialylation of MUC4β N-glycans by ST6GAL1 orchestrates human airway epithelial cell differentiation associated with Type-2 inflammation.

Zhou X, Kinlough CL, Hughey RP, Jin M, Inoue H, Etling E, Modena BD, Kaminski N, Bleecker ER, Meyers DA, Jarjour NN, Trudeau JB, Holguin F, Ray A, Wenzel SE.

JCI Insight. 2019 Feb 7. pii: 122475. doi: 10.1172/jci.insight.122475. [Epub ahead of print]

3.

Multiview Cluster Analysis Identifies Variable Corticosteroid Response Phenotypes in Severe Asthma.

Wu W, Bang S, Bleecker ER, Castro M, Denlinger L, Erzurum SC, Fahy JV, Fitzpatrick AM, Gaston BM, Hastie AT, Israel E, Jarjour NN, Levy BD, Mauger DT, Meyers DA, Moore WC, Peters M, Phillips BR, Phipatanakul W, Sorkness RL, Wenzel SE.

Am J Respir Crit Care Med. 2019 Jan 25. doi: 10.1164/rccm.201808-1543OC. [Epub ahead of print]

PMID:
30682261
4.

Dysfunctional ErbB2, an EGF receptor family member, hinders repair of airway epithelial cells from asthmatic patients.

Inoue H, Hattori T, Zhou X, Etling EB, Modena BD, Trudeau JB, Holguin F, Wenzel SE.

J Allergy Clin Immunol. 2019 Jan 10. pii: S0091-6749(19)30008-9. doi: 10.1016/j.jaci.2018.11.046. [Epub ahead of print]

PMID:
30639343
5.

Racial disparities in asthma-related health care use in the National Heart, Lung, and Blood Institute's Severe Asthma Research Program.

Fitzpatrick AM, Gillespie SE, Mauger DT, Phillips BR, Bleecker ER, Israel E, Meyers DA, Moore WC, Sorkness RL, Wenzel SE, Bacharier LB, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston BM, Jarjour NN, Larkin A, Levy BD, Ly NP, Ortega VE, Peters SP, Phipatanakul W, Ramratnam S, Teague WG.

J Allergy Clin Immunol. 2019 Jan 8. pii: S0091-6749(18)31732-9. doi: 10.1016/j.jaci.2018.11.022. [Epub ahead of print]

PMID:
30635198
6.

Adapting clinical trial design to maintain meaningful outcomes during a multicenter asthma trial in the precision medicine era.

Sorkness CA, King TS, Dyer AM, Chinchilli VM, Mauger DT, Krishnan JA, Blake K, Castro M, Covar R, Israel E, Kraft M, Lang JE, Lugogo N, Peters SP, Wechsler ME, Wenzel SE, Lazarus SC; National Heart Lung and Blood Institute's “AsthmaNet”.

Contemp Clin Trials. 2019 Feb;77:98-103. doi: 10.1016/j.cct.2018.12.012. Epub 2018 Dec 27.

PMID:
30593883
7.

Clinical Issues in Severe Asthma: Debates and Discussions About Personalizing Patient Management.

Panettieri RA Jr, Wechsler ME, Wenzel SE.

Chest. 2018 Dec;154(6):1459-1460. doi: 10.1016/j.chest.2018.09.002.

PMID:
30526975
8.

Empowerment of 15-lipoxygenase catalytic competence in selective oxidation of membrane ETE-PE to ferroptotic death signals, HpETE-PE.

Anthonymuthu TS, Kenny EM, Shrivastava IH, Tyurina YY, Hier ZE, Ting HC, Dar H, Tyurin VA, Nesterova A, Amoscato AA, Mikulska-Ruminska K, Rosenbaum JC, Mao G, Jinming Z, Conrad M, Kellum JA, Wenzel SE, VanDemark AP, Bahar I, Kagan VE, Bayir H.

J Am Chem Soc. 2018 Dec 7. doi: 10.1021/jacs.8b09913. [Epub ahead of print]

PMID:
30525572
9.

Clinical Issues in Severe Asthma: Consensus and Controversies on the Road to Precision Medicine.

Bleecker ER, Panettieri RA Jr, Wenzel SE.

Chest. 2018 Oct;154(4):982-983. doi: 10.1016/j.chest.2018.08.1022.

PMID:
30290932
10.

Internet-Based Cognitive-Behavioral Therapy for Insomnia in Adults With Asthma: A Pilot Study.

Luyster FS, Ritterband LM, Sereika SM, Buysse DJ, Wenzel SE, Strollo PJ.

Behav Sleep Med. 2018 Sep 25:1-13. doi: 10.1080/15402002.2018.1518229. [Epub ahead of print]

PMID:
30252506
11.

Association of free vitamin D3 concentrations and asthma treatment failures in the VIDA Trial.

Lima JJ, Castro M, King TS, Lang JE, Ortega VE, Peters SP, Denlinger LC, Israel E, Sorkness CA, Wechsler ME, Wenzel SE, Smith LJ.

Ann Allergy Asthma Immunol. 2018 Oct;121(4):444-450.e1. doi: 10.1016/j.anai.2018.06.001. Epub 2018 Jun 14.

PMID:
29908319
12.

Prospective predictors of exacerbation status in severe asthma over a 3-year follow-up.

Kimura H, Konno S, Makita H, Taniguchi N, Shimizu K, Suzuki M, Kimura H, Goudarzi H, Nakamaru Y, Ono J, Ohta S, Izuhara K, Ito YM, Wenzel SE, Nishimura M; Hi-CARAT investigators.

Clin Exp Allergy. 2018 Sep;48(9):1137-1146. doi: 10.1111/cea.13170. Epub 2018 Jun 4.

PMID:
29781543
13.

Liberty Asthma QUEST: Phase 3 Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate Dupilumab Efficacy/Safety in Patients with Uncontrolled, Moderate-to-Severe Asthma.

Busse WW, Maspero JF, Rabe KF, Papi A, Wenzel SE, Ford LB, Pavord ID, Zhang B, Staudinger H, Pirozzi G, Amin N, Akinlade B, Eckert L, Chao J, Graham NMH, Teper A.

Adv Ther. 2018 May;35(5):737-748. doi: 10.1007/s12325-018-0702-4. Epub 2018 May 3.

14.

Pruning of the Pulmonary Vasculature in Asthma. The Severe Asthma Research Program (SARP) Cohort.

Ash SY, Rahaghi FN, Come CE, Ross JC, Colon AG, Cardet-Guisasola JC, Dunican EM, Bleecker ER, Castro M, Fahy JV, Fain SB, Gaston BM, Hoffman EA, Jarjour NN, Mauger DT, Wenzel SE, Levy BD, San Jose Estepar R, Israel E, Washko GR; SARP Investigators.

Am J Respir Crit Care Med. 2018 Jul 1;198(1):39-50. doi: 10.1164/rccm.201712-2426OC.

PMID:
29672122
15.

Effects of endogenous sex hormones on lung function and symptom control in adolescents with asthma.

DeBoer MD, Phillips BR, Mauger DT, Zein J, Erzurum SC, Fitzpatrick AM, Gaston BM, Myers R, Ross KR, Chmiel J, Lee MJ, Fahy JV, Peters M, Ly NP, Wenzel SE, Fajt ML, Holguin F, Moore WC, Peters SP, Meyers D, Bleecker ER, Castro M, Coverstone AM, Bacharier LB, Jarjour NN, Sorkness RL, Ramratnam S, Irani AM, Israel E, Levy B, Phipatanakul W, Gaffin JM, Gerald Teague W.

BMC Pulm Med. 2018 Apr 10;18(1):58. doi: 10.1186/s12890-018-0612-x.

16.

ALX receptor ligands define a biochemical endotype for severe asthma.

Ricklefs I, Barkas I, Duvall MG, Cernadas M, Grossman NL, Israel E, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Denlinger LC, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, Hastie AT, Johansson MW, Peters MC, Phillips BR, Levy BD; National Heart Lung and Blood Institute’s Severe Asthma Research Program- Investigators.

JCI Insight. 2018 Mar 22;3(6). pii: 120932. doi: 10.1172/jci.insight.120932. [Epub ahead of print] No abstract available.

17.

Refractory airway type 2 inflammation in a large subgroup of asthmatic patients treated with inhaled corticosteroids.

Peters MC, Kerr S, Dunican EM, Woodruff PG, Fajt ML, Levy BD, Israel E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, Coverstone AM, Castro M, Hastie AT, Bleecker ER, Wenzel SE, Fahy JV; National Heart, Lung and Blood Institute Severe Asthma Research Program 3.

J Allergy Clin Immunol. 2019 Jan;143(1):104-113.e14. doi: 10.1016/j.jaci.2017.12.1009. Epub 2018 Mar 7.

PMID:
29524537
18.

Differentiation of quantitative CT imaging phenotypes in asthma versus COPD.

Choi S, Haghighi B, Choi J, Hoffman EA, Comellas AP, Newell JD, Wenzel SE, Castro M, Fain SB, Jarjour NN, Schiebler ML, Barr RG, Han MK, Bleecker ER, Cooper CB, Couper D, Hansel N, Kanner RE, Kazerooni EA, Kleerup EAC, Martinez FJ, O'Neal WK, Woodruff PG, Lin CL.

BMJ Open Respir Res. 2017 Nov 9;4(1):e000252. doi: 10.1136/bmjresp-2017-000252. eCollection 2017. Erratum in: BMJ Open Respir Res. 2018 Mar 6;5(1):e000252corr1.

19.

Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction.

Dunican EM, Elicker BM, Gierada DS, Nagle SK, Schiebler ML, Newell JD, Raymond WW, Lachowicz-Scroggins ME, Di Maio S, Hoffman EA, Castro M, Fain SB, Jarjour NN, Israel E, Levy BD, Erzurum SC, Wenzel SE, Meyers DA, Bleecker ER, Phillips BR, Mauger DT, Gordon ED, Woodruff PG, Peters MC, Fahy JV; National Heart Lung and Blood Institute (NHLBI) Severe Asthma Research Program (SARP).

J Clin Invest. 2018 Mar 1;128(3):997-1009. doi: 10.1172/JCI95693. Epub 2018 Feb 5.

20.

ATP12A promotes mucus dysfunction during Type 2 airway inflammation.

Lennox AT, Coburn SL, Leech JA, Heidrich EM, Kleyman TR, Wenzel SE, Pilewski JM, Corcoran TE, Myerburg MM.

Sci Rep. 2018 Feb 1;8(1):2109. doi: 10.1038/s41598-018-20444-8.

21.

Crosstalk between mAChRM3 and β2AR, via acetylcholine PI3/PKC/PBEP1/Raf-1 MEK1/2/ERK1/2 pathway activation, in human bronchial epithelial cells after long-term cigarette smoke exposure.

Albano GD, Bonanno A, Moscato M, Anzalone G, Di Sano C, Riccobono L, Wenzel SE, Profita M.

Life Sci. 2018 Jan 1;192:99-109. doi: 10.1016/j.lfs.2017.11.034. Epub 2017 Nov 22.

PMID:
29175450
22.

Association of interleukin 1 receptor-like 1 gene polymorphisms with eosinophilic phenotype in Japanese adults with asthma.

Inoue H, Ito I, Niimi A, Matsumoto H, Oguma T, Tajiri T, Iwata T, Nagasaki T, Kanemitsu Y, Morishima T, Hirota T, Tamari M, Wenzel SE, Mishima M.

Respir Investig. 2017 Nov;55(6):338-347. doi: 10.1016/j.resinv.2017.08.006. Epub 2017 Sep 22.

PMID:
29153414
23.

Aerosol deposition predictions in computed tomography-derived skeletons from severe asthmatics: A feasibility study.

Miyawaki S, Hoffman EA, Wenzel SE, Lin CL.

Clin Biomech (Bristol, Avon). 2017 Nov 4. pii: S0268-0033(17)30273-5. doi: 10.1016/j.clinbiomech.2017.10.020. [Epub ahead of print]

PMID:
29129332
24.

Peripheral Eosinophilia in Patients With Inflammatory Bowel Disease Defines an Aggressive Disease Phenotype.

Click B, Anderson AM, Koutroubakis IE, Rivers CR, Babichenko D, Machicado JD, Hartman DJ, Hashash JG, Dunn MA, Schwartz M, Swoger J, Barrie A III, Wenzel SE, Regueiro M, Binion DG.

Am J Gastroenterol. 2017 Dec;112(12):1849-1858. doi: 10.1038/ajg.2017.402. Epub 2017 Nov 7.

PMID:
29112200
25.

Internet-Based Monitoring in the Severe Asthma Research Program Identifies a Subgroup of Patients With Labile Asthma Control.

Wong-McGrath K, Denlinger LC, Bleecker ER, Castro M, Gaston B, Israel E, Jarjour NN, Mauger DT, Peters S, Phillips BR, Wenzel SE, Fahy JV, Peters MC; National Heart Lung and Blood Institute’s Severe Asthma Research Program-3 Investigators.

Chest. 2018 Feb;153(2):378-386. doi: 10.1016/j.chest.2017.10.017. Epub 2017 Oct 26.

26.

PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals.

Wenzel SE, Tyurina YY, Zhao J, St Croix CM, Dar HH, Mao G, Tyurin VA, Anthonymuthu TS, Kapralov AA, Amoscato AA, Mikulska-Ruminska K, Shrivastava IH, Kenny EM, Yang Q, Rosenbaum JC, Sparvero LJ, Emlet DR, Wen X, Minami Y, Qu F, Watkins SC, Holman TR, VanDemark AP, Kellum JA, Bahar I, Bayır H, Kagan VE.

Cell. 2017 Oct 19;171(3):628-641.e26. doi: 10.1016/j.cell.2017.09.044.

27.

An invisible disease: severe asthma is more than just "bad asthma".

Wenzel SE, Brillhart S, Nowack K.

Eur Respir J. 2017 Sep 20;50(3). pii: 1701109. doi: 10.1183/13993003.01109-2017. Print 2017 Sep. No abstract available.

PMID:
28931667
28.

Distinct Phenotypes of Smokers with Fixed Airflow Limitation Identified by Cluster Analysis of Severe Asthma.

Konno S, Taniguchi N, Makita H, Nakamaru Y, Shimizu K, Shijubo N, Fuke S, Takeyabu K, Oguri M, Kimura H, Maeda Y, Suzuki M, Nagai K, Ito YM, Wenzel SE, Nishimura M; HiCARAT Investigators ‡; HiCARAT Investigators.

Ann Am Thorac Soc. 2018 Jan;15(1):33-41. doi: 10.1513/AnnalsATS.201701-065OC.

PMID:
28910142
29.

Baseline Features of the Severe Asthma Research Program (SARP III) Cohort: Differences with Age.

Teague WG, Phillips BR, Fahy JV, Wenzel SE, Fitzpatrick AM, Moore WC, Hastie AT, Bleecker ER, Meyers DA, Peters SP, Castro M, Coverstone AM, Bacharier LB, Ly NP, Peters MC, Denlinger LC, Ramratnam S, Sorkness RL, Gaston BM, Erzurum SC, Comhair SAA, Myers RE, Zein J, DeBoer MD, Irani AM, Israel E, Levy B, Cardet JC, Phipatanakul W, Gaffin JM, Holguin F, Fajt ML, Aujla SJ, Mauger DT, Jarjour NN.

J Allergy Clin Immunol Pract. 2018 Mar - Apr;6(2):545-554.e4. doi: 10.1016/j.jaip.2017.05.032. Epub 2017 Aug 31.

30.

"Only a Life Lived for Others Is Worth Living": Redox Signaling by Oxygenated Phospholipids in Cell Fate Decisions.

Tyurina YY, Shrivastava I, Tyurin VA, Mao G, Dar HH, Watkins S, Epperly M, Bahar I, Shvedova AA, Pitt B, Wenzel SE, Mallampalli RK, Sadovsky Y, Gabrilovich D, Greenberger JS, Bayır H, Kagan VE.

Antioxid Redox Signal. 2018 Nov 1;29(13):1333-1358. doi: 10.1089/ars.2017.7124. Epub 2017 Oct 16.

PMID:
28835115
31.

Natural killer cell-mediated inflammation resolution is disabled in severe asthma.

Duvall MG, Barnig C, Cernadas M, Ricklefs I, Krishnamoorthy N, Grossman NL, Bhakta NR, Fahy JV, Bleecker ER, Castro M, Erzurum SC, Gaston BM, Jarjour NN, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, Hastie AT, Johansson MW, Peters MC, Phillips BR, Israel E, Levy BD; National Heart, Lung, and Blood Institute’s Severe Asthma Research Program-3 Investigators.

Sci Immunol. 2017 Mar 10;2(9). pii: eaam5446. doi: 10.1126/sciimmunol.aam5446.

32.

Expression of intelectin-1 in bronchial epithelial cells of asthma is correlated with T-helper 2 (Type-2) related parameters and its function.

Watanabe T, Chibana K, Shiobara T, Tei R, Koike R, Nakamura Y, Arai R, Horigane Y, Shimizu Y, Takemasa A, Fukuda T, Wenzel SE, Ishii Y.

Allergy Asthma Clin Immunol. 2017 Aug 1;13:35. doi: 10.1186/s13223-017-0207-8. eCollection 2017.

33.

ALX receptor ligands define a biochemical endotype for severe asthma.

Ricklefs I, Barkas I, Duvall MG, Cernadas M, Grossman NL, Israel E, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Denlinger LC, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, Hastie AT, Johansson MW, Peters MC, Phillips BR, Levy BD; National Heart Lung and Blood Institute’s Severe Asthma Research Program-3 Investigators.

JCI Insight. 2017 Jul 20;2(14). pii: 93534. doi: 10.1172/jci.insight.93534. [Epub ahead of print]

34.

Severe asthma in humans and mouse model suggests a CXCL10 signature underlies corticosteroid-resistant Th1 bias.

Gauthier M, Chakraborty K, Oriss TB, Raundhal M, Das S, Chen J, Huff R, Sinha A, Fajt M, Ray P, Wenzel SE, Ray A.

JCI Insight. 2017 Jul 6;2(13). pii: 94580. doi: 10.1172/jci.insight.94580. [Epub ahead of print]

35.

American Thoracic Society/National Heart, Lung, and Blood Institute Asthma-Chronic Obstructive Pulmonary Disease Overlap Workshop Report.

Woodruff PG, van den Berge M, Boucher RC, Brightling C, Burchard EG, Christenson SA, Han MK, Holtzman MJ, Kraft M, Lynch DA, Martinez FD, Reddel HK, Sin DD, Washko GR, Wenzel SE, Punturieri A, Freemer MM, Wise RA.

Am J Respir Crit Care Med. 2017 Aug 1;196(3):375-381. doi: 10.1164/rccm.201705-0973WS.

36.

IRF5 distinguishes severe asthma in humans and drives Th1 phenotype and airway hyperreactivity in mice.

Oriss TB, Raundhal M, Morse C, Huff RE, Das S, Hannum R, Gauthier MC, Scholl KL, Chakraborty K, Nouraie SM, Wenzel SE, Ray P, Ray A.

JCI Insight. 2017 May 18;2(10). pii: 91019. doi: 10.1172/jci.insight.91019. [Epub ahead of print]

37.

Giants in Chest Medicine: Paul M. O'Byrne, MBBCh, FCCP.

Wenzel SE.

Chest. 2017 Mar;151(3):529-530. doi: 10.1016/j.chest.2016.07.023. No abstract available.

PMID:
28279271
38.

Consistency of T2 Gene Signatures in Severe Asthma. Key to Effective Treatments or Merely the Tip of the Iceberg?

Modena BD, Wenzel SE.

Am J Respir Crit Care Med. 2017 Feb 15;195(4):411-412. doi: 10.1164/rccm.201609-1854ED. No abstract available.

PMID:
28199166
39.

Quantitative computed tomographic imaging-based clustering differentiates asthmatic subgroups with distinctive clinical phenotypes.

Choi S, Hoffman EA, Wenzel SE, Castro M, Fain S, Jarjour N, Schiebler ML, Chen K, Lin CL; National Heart, Lung and Blood Institute's Severe Asthma Research Program.

J Allergy Clin Immunol. 2017 Sep;140(3):690-700.e8. doi: 10.1016/j.jaci.2016.11.053. Epub 2017 Jan 29.

40.

Gene Expression Correlated with Severe Asthma Characteristics Reveals Heterogeneous Mechanisms of Severe Disease.

Modena BD, Bleecker ER, Busse WW, Erzurum SC, Gaston BM, Jarjour NN, Meyers DA, Milosevic J, Tedrow JR, Wu W, Kaminski N, Wenzel SE.

Am J Respir Crit Care Med. 2017 Jun 1;195(11):1449-1463. doi: 10.1164/rccm.201607-1407OC.

41.

Effects of Age and Disease Severity on Systemic Corticosteroid Responses in Asthma.

Phipatanakul W, Mauger DT, Sorkness RL, Gaffin JM, Holguin F, Woodruff PG, Ly NP, Bacharier LB, Bhakta NR, Moore WC, Bleecker ER, Hastie AT, Meyers DA, Castro M, Fahy JV, Fitzpatrick AM, Gaston BM, Jarjour NN, Levy BD, Peters SP, Teague WG, Fajt M, Wenzel SE, Erzurum SC, Israel E; Severe Asthma Research Program.

Am J Respir Crit Care Med. 2017 Jun 1;195(11):1439-1448. doi: 10.1164/rccm.201607-1453OC.

42.

Severe asthma and asthma-chronic obstructive pulmonary disease syndrome - Authors' reply.

Wenzel SE, Jayawardena S, Graham NM, Pirozzi G, Teper A.

Lancet. 2016 Dec 3;388(10061):2742. doi: 10.1016/S0140-6736(16)31720-2. Epub 2016 Dec 2. No abstract available.

PMID:
27924776
43.

Features of the bronchial bacterial microbiome associated with atopy, asthma, and responsiveness to inhaled corticosteroid treatment.

Durack J, Lynch SV, Nariya S, Bhakta NR, Beigelman A, Castro M, Dyer AM, Israel E, Kraft M, Martin RJ, Mauger DT, Rosenberg SR, Sharp-King T, White SR, Woodruff PG, Avila PC, Denlinger LC, Holguin F, Lazarus SC, Lugogo N, Moore WC, Peters SP, Que L, Smith LJ, Sorkness CA, Wechsler ME, Wenzel SE, Boushey HA, Huang YJ; National Heart, Lung and Blood Institute's “AsthmaNet”.

J Allergy Clin Immunol. 2017 Jul;140(1):63-75. doi: 10.1016/j.jaci.2016.08.055. Epub 2016 Nov 10.

44.

Development of New Therapies for Severe Asthma.

Fajt ML, Wenzel SE.

Allergy Asthma Immunol Res. 2017 Jan;9(1):3-14. doi: 10.4168/aair.2017.9.1.3. Review.

45.

Association Between Insomnia and Asthma Burden in the Severe Asthma Research Program (SARP) III.

Luyster FS, Strollo PJ Jr, Holguin F, Castro M, Dunican EM, Fahy J, Gaston B, Israel E, Jarjour NN, Mauger DT, Moore WC, Wenzel SE.

Chest. 2016 Dec;150(6):1242-1250. doi: 10.1016/j.chest.2016.09.020. Epub 2016 Oct 6.

46.

Automatic construction of subject-specific human airway geometry including trifurcations based on a CT-segmented airway skeleton and surface.

Miyawaki S, Tawhai MH, Hoffman EA, Wenzel SE, Lin CL.

Biomech Model Mechanobiol. 2017 Apr;16(2):583-596. doi: 10.1007/s10237-016-0838-6. Epub 2016 Oct 4.

47.

l-citrulline prevents asymmetric dimethylarginine-mediated reductions in nitric oxide and nitrosative stress in primary human airway epithelial cells.

Winnica D, Que LG, Baffi C, Grasemann H, Fiedler K, Yang Z, Etling E, Wasil K, Wenzel SE, Freeman B, Holguin F.

Clin Exp Allergy. 2017 Feb;47(2):190-199. doi: 10.1111/cea.12802. Epub 2016 Oct 4.

48.

Inflammatory and Comorbid Features of Patients with Severe Asthma and Frequent Exacerbations.

Denlinger LC, Phillips BR, Ramratnam S, Ross K, Bhakta NR, Cardet JC, Castro M, Peters SP, Phipatanakul W, Aujla S, Bacharier LB, Bleecker ER, Comhair SA, Coverstone A, DeBoer M, Erzurum SC, Fain SB, Fajt M, Fitzpatrick AM, Gaffin J, Gaston B, Hastie AT, Hawkins GA, Holguin F, Irani AM, Israel E, Levy BD, Ly N, Meyers DA, Moore WC, Myers R, Opina MT, Peters MC, Schiebler ML, Sorkness RL, Teague WG, Wenzel SE, Woodruff PG, Mauger DT, Fahy JV, Jarjour NN; National Heart, Lung, and Blood Institute’s Severe Asthma Research Program-3 Investigators.

Am J Respir Crit Care Med. 2017 Feb 1;195(3):302-313. doi: 10.1164/rccm.201602-0419OC.

49.

Antiinflammatory effects of bromodomain and extraterminal domain inhibition in cystic fibrosis lung inflammation.

Chen K, Campfield BT, Wenzel SE, McAleer JP, Kreindler JL, Kurland G, Gopal R, Wang T, Chen W, Eddens T, Quinn KM, Myerburg MM, Horne WT, Lora JM, Albrecht BK, Pilewski JM, Kolls JK.

JCI Insight. 2016 Jul 21;1(11). pii: e87168.

50.

Adiposity influences airway wall thickness and the asthma phenotype of HIV-associated obstructive lung disease: a cross-sectional study.

Barton JH, Ireland A, Fitzpatrick M, Kessinger C, Camp D, Weinman R, McMahon D, Leader JK, Holguin F, Wenzel SE, Morris A, Gingo MR.

BMC Pulm Med. 2016 Aug 4;16(1):111. doi: 10.1186/s12890-016-0274-5.

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