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Evidence for HIV-1 cure after CCR5Δ32/Δ32 allogeneic haemopoietic stem-cell transplantation 30 months post analytical treatment interruption: a case report.

Gupta RK, Peppa D, Hill AL, Gálvez C, Salgado M, Pace M, McCoy LE, Griffith SA, Thornhill J, Alrubayyi A, Huyveneers LEP, Nastouli E, Grant P, Edwards SG, Innes AJ, Frater J, Nijhuis M, Wensing AMJ, Martinez-Picado J, Olavarria E.

Lancet HIV. 2020 Mar 9. pii: S2352-3018(20)30069-2. doi: 10.1016/S2352-3018(20)30069-2. [Epub ahead of print]


Virological suppression and clinical management in response to viremia in South African HIV treatment program: A multicenter cohort study.

Hermans LE, Carmona S, Nijhuis M, Tempelman HA, Richman DD, Moorhouse M, Grobbee DE, Venter WDF, Wensing AMJ.

PLoS Med. 2020 Feb 25;17(2):e1003037. doi: 10.1371/journal.pmed.1003037. eCollection 2020 Feb.


2019 update of the drug resistance mutations in HIV-1.

Wensing AM, Calvez V, Ceccherini-Silberstein F, Charpentier C, Günthard HF, Paredes R, Shafer RW, Richman DD.

Top Antivir Med. 2019 Sep;27(3):111-121.


HIV-1 remission following CCR5Δ32/Δ32 haematopoietic stem-cell transplantation.

Gupta RK, Abdul-Jawad S, McCoy LE, Mok HP, Peppa D, Salgado M, Martinez-Picado J, Nijhuis M, Wensing AMJ, Lee H, Grant P, Nastouli E, Lambert J, Pace M, Salasc F, Monit C, Innes AJ, Muir L, Waters L, Frater J, Lever AML, Edwards SG, Gabriel IH, Olavarria E.

Nature. 2019 Apr;568(7751):244-248. doi: 10.1038/s41586-019-1027-4. Epub 2019 Mar 5.


Efficacy and safety of long-term maraviroc use in a heterogeneous group of HIV-infected patients: A retrospective cohort study.

Weehuizen JM, Wensing AMJ, Mudrikova T, Wit FWNM, Hoepelman AIM.

Int J Antimicrob Agents. 2019 Aug;54(2):215-222. doi: 10.1016/j.ijantimicag.2019.02.018. Epub 2019 Mar 1.


Immunogenicity of Influenza Vaccines: Evidence for Differential Effect of Secondary Vaccination on Humoral and Cellular Immunity.

Rosendahl Huber SK, Hendriks M, Jacobi RHJ, van de Kassteele J, Mandersloot-Oskam JC, van Boxtel RAJ, Wensing AMJ, Rots NY, Luytjes W, van Beek J.

Front Immunol. 2019 Jan 29;9:3103. doi: 10.3389/fimmu.2018.03103. eCollection 2018.


Reply to Ambrosioni et al.

Günthard HF, Calvez V, Paredes R, Pillay D, Shafer RW, Wensing AM, Jacobsen DM, Richman DD.

Clin Infect Dis. 2019 May 17;68(11):1977-1978. doi: 10.1093/cid/ciy1022. No abstract available.


Development of sensitive ddPCR assays to reliably quantify the proviral DNA reservoir in all common circulating HIV subtypes and recombinant forms.

Bosman KJ, Wensing AM, Pijning AE, van Snippenberg WJ, van Ham PM, de Jong DM, Hoepelman AI, Nijhuis M.

J Int AIDS Soc. 2018 Sep;21(9):e25185. doi: 10.1002/jia2.25185.


REtrieval And cure of Chronic Hepatitis C (REACH): Results of micro-elimination in the Utrecht province.

Kracht PAM, Arends JE, van Erpecum KJ, Thijsen SFT, Vlaminckx BJM, Weersink AJL, Wensing AMJ, Deege MPH, Dimmendaal M, Stadhouders PHGM, Friederich PW, Verhagen MAMT, Boland GJ, Hoepelman AIM.

Liver Int. 2019 Mar;39(3):455-462. doi: 10.1111/liv.13959. Epub 2018 Oct 16.


Human Immunodeficiency Virus Drug Resistance: 2018 Recommendations of the International Antiviral Society-USA Panel.

Günthard HF, Calvez V, Paredes R, Pillay D, Shafer RW, Wensing AM, Jacobsen DM, Richman DD.

Clin Infect Dis. 2019 Jan 7;68(2):177-187. doi: 10.1093/cid/ciy463.


Rapid Rebound of a Preexisting CXCR4-tropic Human Immunodeficiency Virus Variant After Allogeneic Transplantation With CCR5 Δ32 Homozygous Stem Cells.

Verheyen J, Thielen A, Lübke N, Dirks M, Widera M, Dittmer U, Kordelas L, Däumer M, de Jong DCM, Wensing AMJ, Kaiser R, Nijhuis M, Esser S.

Clin Infect Dis. 2019 Feb 1;68(4):684-687. doi: 10.1093/cid/ciy565.


All-printed cell counting chambers with on-chip sample preparation for point-of-care CD4 counting.

Wasserberg D, Zhang X, Breukers C, Connell BJ, Baeten E, van den Blink D, S O L À Benet È, Bloem AC, Nijhuis M, Wensing AMJ, Terstappen LWMM, Beck M.

Biosens Bioelectron. 2018 Oct 15;117:659-668. doi: 10.1016/j.bios.2018.07.002. Epub 2018 Jul 3.


Immune-escape mutations and stop-codons in HBsAg develop in a large proportion of patients with chronic HBV infection exposed to anti-HBV drugs in Europe.

Colagrossi L, Hermans LE, Salpini R, Di Carlo D, Pas SD, Alvarez M, Ben-Ari Z, Boland G, Bruzzone B, Coppola N, Seguin-Devaux C, Dyda T, Garcia F, Kaiser R, Köse S, Krarup H, Lazarevic I, Lunar MM, Maylin S, Micheli V, Mor O, Paraschiv S, Paraskevis D, Poljak M, Puchhammer-Stöckl E, Simon F, Stanojevic M, Stene-Johansen K, Tihic N, Trimoulet P, Verheyen J, Vince A, Lepej SZ, Weis N, Yalcinkaya T, Boucher CAB, Wensing AMJ, Perno CF, Svicher V; HEPVIR working group of the European Society for translational antiviral research (ESAR).

BMC Infect Dis. 2018 Jun 1;18(1):251. doi: 10.1186/s12879-018-3161-2.


Impact of the HIV-1 genetic background and HIV-1 population size on the evolution of raltegravir resistance.

Fun A, Leitner T, Vandekerckhove L, Däumer M, Thielen A, Buchholz B, Hoepelman AIM, Gisolf EH, Schipper PJ, Wensing AMJ, Nijhuis M.

Retrovirology. 2018 Jan 5;15(1):1. doi: 10.1186/s12977-017-0384-z.


Effect of HIV-1 low-level viraemia during antiretroviral therapy on treatment outcomes in WHO-guided South African treatment programmes: a multicentre cohort study.

Hermans LE, Moorhouse M, Carmona S, Grobbee DE, Hofstra LM, Richman DD, Tempelman HA, Venter WDF, Wensing AMJ.

Lancet Infect Dis. 2018 Feb;18(2):188-197. doi: 10.1016/S1473-3099(17)30681-3. Epub 2017 Nov 17. Erratum in: Lancet Infect Dis. 2017 Nov 24;:.


Viral reactivations and associated outcomes in the context of immune reconstitution after pediatric hematopoietic cell transplantation.

Admiraal R, de Koning CCH, Lindemans CA, Bierings MB, Wensing AMJ, Versluys AB, Wolfs TFW, Nierkens S, Boelens JJ.

J Allergy Clin Immunol. 2017 Dec;140(6):1643-1650.e9. doi: 10.1016/j.jaci.2016.12.992. Epub 2017 Apr 7.


Acute influenza virus-associated encephalitis and encephalopathy in adults: a challenging diagnosis.

Meijer WJ, Linn FH, Wensing AM, Leavis HL, van Riel D, GeurtsvanKessel CH, Wattjes MP, Murk JL.

JMM Case Rep. 2016 Dec 19;3(6):e005076. doi: 10.1099/jmmcr.0.005076. eCollection 2016 Dec.


High Rates of Transmission of Drug-resistant HIV in Aruba Resulting in Reduced Susceptibility to the WHO Recommended First-line Regimen in Nearly Half of Newly Diagnosed HIV-infected Patients.

Hofstra LM, Sánchez Rivas E, Nijhuis M, Bank LEA, Wilkinson E, Kelly K, Mudrikova T, Schuurman R, de Oliveira T, de Kort J, Wensing AMJ.

Clin Infect Dis. 2017 Apr 15;64(8):1092-1097. doi: 10.1093/cid/cix056.


2017 Update of the Drug Resistance Mutations in HIV-1.

Wensing AM, Calvez V, Günthard HF, Johnson VA, Paredes R, Pillay D, Shafer RW, Richman DD.

Top Antivir Med. 2016 Dec;24(4):132-133.


Influenza vaccination in healthcare workers; comparison of side effects and preferred route of administration of intradermal versus intramuscular administration.

Meijer WJ, Wensing AMJ, Bos AA, Kuiphuis JCF, Hagelen EMM, Wilschut JC, de Vries MJT, Riezebos-Brilman A.

Vaccine. 2017 Mar 13;35(11):1517-1523. doi: 10.1016/j.vaccine.2017.01.065. Epub 2017 Feb 10.


Genotypic susceptibility score (GSS) and CD4+ T cell recovery in HIV-1 patients with suppressed viral load.

Gonzalez-Serna A, Glas AC, Brumme CJ, Poon AF, Nohpal De La Rosa A, Mudrikova T, Dias Lima V, Wensing AM, Harrigan R.

J Antimicrob Chemother. 2017 Feb;72(2):496-503. doi: 10.1093/jac/dkw455. Epub 2016 Dec 20.


The hepatitis C virus nonstructural protein 3 Q80K polymorphism is frequently detected and transmitted among HIV-infected MSM in the Netherlands.

Newsum AM, Ho CK, Lieveld FI, van de Laar TJ, Koekkoek SM, Rebers SP, van der Meer JT, Wensing AM, Boland GJ, Arends JE, van Erpecum KJ, Prins M, Molenkamp R, Schinkel J.

AIDS. 2017 Jan 2;31(1):105-112.


 Resistance-associated polymorphisms in Dutch hepatitis C genotype 1a patients with and without HIV infection.

Lieveld FI, Swaans N, Newsum AM, Ho CK, Schinkel J, Molenkamp R, van der Meer JT, Arends JE, Hoepelman AI, Wensing AM, Siersema PD, van Erpecum KJ, Boland GJ.

Ann Hepatol. 2016 Sep-Oct;15(5):696-704. doi: 10.5604/16652681.1212426.


Continuous intravenous infusion of enfuvirtide in a patient with a multidrug-resistant HIV strain.

Neijzen RW, Van Maarseveen EM, Hoepelman AI, Wensing AM, Bonora S, D'Avolio A, Mudrikova T.

Int J Clin Pharm. 2016 Aug;38(4):749-51. doi: 10.1007/s11096-016-0316-3. Epub 2016 May 14.


Astrovirus outbreak at a pediatric hematology and hematopoietic stem cell transplant unit despite strict hygiene rules.

van der Doef HP, Bathoorn E, van der Linden MP, Wolfs TF, Minderhoud AL, Bierings MB, Wensing AM, Lindemans CA.

Bone Marrow Transplant. 2016 May;51(5):747-50. doi: 10.1038/bmt.2015.337. Epub 2016 Jan 25. No abstract available.


The presence of protective cytotoxic T lymphocytes does not correlate with shorter lifespans of productively infected cells in HIV-1 infection.

Spits HB, Mudrikova T, Schellens IM, Wensing AM, Prins JM, Feuth T, Spierings E, Nijhuis M, van Baarle D, Borghans JA.

AIDS. 2016 Jan 2;30(1):9-17. doi: 10.1097/QAD.0000000000000914.


HIV-1 Drug Resistance Mutations: Potential Applications for Point-of-Care Genotypic Resistance Testing.

Rhee SY, Jordan MR, Raizes E, Chua A, Parkin N, Kantor R, Van Zyl GU, Mukui I, Hosseinipour MC, Frenkel LM, Ndembi N, Hamers RL, Rinke de Wit TF, Wallis CL, Gupta RK, Fokam J, Zeh C, Schapiro JM, Carmona S, Katzenstein D, Tang M, Aghokeng AF, De Oliveira T, Wensing AM, Gallant JE, Wainberg MA, Richman DD, Fitzgibbon JE, Schito M, Bertagnolio S, Yang C, Shafer RW.

PLoS One. 2015 Dec 30;10(12):e0145772. doi: 10.1371/journal.pone.0145772. eCollection 2015.


2015 Update of the Drug Resistance Mutations in HIV-1.

Wensing AM, Calvez V, Günthard HF, Johnson VA, Paredes R, Pillay D, Shafer RW, Richman DD.

Top Antivir Med. 2015 Oct-Nov;23(4):132-41.


Transmission of HIV Drug Resistance and the Predicted Effect on Current First-line Regimens in Europe.

Hofstra LM, Sauvageot N, Albert J, Alexiev I, Garcia F, Struck D, Van de Vijver DAMC, Åsjö B, Beshkov D, Coughlan S, Descamps D, Griskevicius A, Hamouda O, Horban A, Van Kasteren M, Kolupajeva T, Kostrikis LG, Liitsola K, Linka M, Mor O, Nielsen C, Otelea D, Paraskevis D, Paredes R, Poljak M, Puchhammer-Stöckl E, Sönnerborg A, Staneková D, Stanojevic M, Van Laethem K, Zazzi M, Zidovec Lepej S, Boucher CAB, Schmit JC, Wensing AMJ; SPREAD Program, Puchhammer-Stockl E, Sarcletti M, Schmied B, Geit M, Balluch G, Vandamme AM, Vercauteren J, Derdelinckx I, Sasse A, Bogaert M, Ceunen H, De Roo A, De Wit S, Echahidi F, Fransen K, Goffard JC, Goubau P, Goudeseune E, Yombi JC, Lacor P, Liesnard C, Moutschen M, Pierard D, Rens R, Schrooten Y, Vaira D, Vandekerckhove LPR, Van den Heuvel A, Van Der Gucht B, Van Ranst M, Van Wijngaerden E, Vandercam B, Vekemans M, Verhofstede C, Clumeck N, Van Laethem K, Beshkov D, Alexiev I, Lepej SZ, Begovac J, Kostrikis L, Demetriades I, Kousiappa I, Demetriou V, Hezka J, Linka M, Maly M, Machala L, Nielsen C, Jørgensen LB, Gerstoft J, Mathiesen L, Pedersen C, Nielsen H, Laursen A, Kvinesdal B, Liitsola K, Ristola M, Suni J, Sutinen J, Descamps D, Assoumou L, Castor G, Grude M, Flandre P, Storto A, Hamouda O, Kücherer C, Berg T, Braun P, Poggensee G, Däumer M, Eberle J, Heiken H, Kaiser R, Knechten H, Korn K, Müller H, Neifer S, Schmidt B, Walter H, Gunsenheimer-Bartmeyer B, Harrer T, Paraskevis D, Hatzakis A, Zavitsanou A, Vassilakis A, Lazanas M, Chini M, Lioni A, Sakka V, Kourkounti S, Paparizos V, Antoniadou A, Papadopoulos A, Poulakou G, Katsarolis I, Protopapas K, Chryssos G, Drimis S, Gargalianos P, Xylomenos G, Lourida G, Psichogiou M, Daikos GL, Sipsas NV, Kontos A, Gamaletsou MN, Koratzanis G, Sambatakou H, Mariolis H, Skoutelis A, Papastamopoulos V, Georgiou O, Panagopoulos P, Maltezos E, Coughlan S, De Gascun C, Byrne C, Duffy M, Bergin C, Reidy D, Farrell G, Lambert J, O'Connor E, Rochford A, Low J, Coakely P, O'Dea S, Hall W, Mor O, Levi I, Chemtob D, Grossman Z, Zazzi M, de Luca A, Balotta C, Riva C, Mussini C, Caramma I, Capetti A, Colombo MC, Rossi C, Prati F, Tramuto F, Vitale F, Ciccozzi M, Angarano G, Rezza G, Kolupajeva T, Vasins O, Griskevicius A, Lipnickiene V, Schmit JC, Struck D, Sauvageot N, Hemmer R, Arendt V, Michaux C, Staub T, Sequin-Devaux C, Wensing AMJ, Boucher CAB, van de Vijver DAMC, van Kessel A, van Bentum PHM, Brinkman K, Connell BJ, van der Ende ME, Hoepelman IM, van Kasteren M, Kuipers M, Langebeek N, Richter C, Santegoets RMWJ, Schrijnders-Gudde L, Schuurman R, van de Ven BJM, Åsjö B, Kran AB, Ormaasen V, Aavitsland P, Horban A, Stanczak JJ, Stanczak GP, Firlag-Burkacka E, Wiercinska-Drapalo A, Jablonowska E, Maolepsza E, Leszczyszyn-Pynka M, Szata W, Camacho R, Palma C, Borges F, Paixão T, Duque V, Araújo F, Otelea D, Paraschiv S, Tudor AM, Cernat R, Chiriac C, Dumitrescu F, Prisecariu LJ, Stanojevic M, Jevtovic D, Salemovic D, Stanekova D, Habekova M, Chabadová Z, Drobkova T, Bukovinova P, Shunnar A, Truska P, Poljak M, Lunar M, Babic D, Tomazic J, Vidmar L, Vovko T, Karner P, Garcia F, Paredes R, Monge S, Moreno S, Del Amo J, Asensi V, Sirvent JL, de Mendoza C, Delgado R, Gutiérrez F, Berenguer J, Garcia-Bujalance S, Stella N, de Los Santos I, Blanco JR, Dalmau D, Rivero M, Segura F, Elías MJP, Alvarez M, Chueca N, Rodríguez-Martín C, Vidal C, Palomares JC, Viciana I, Viciana P, Cordoba J, Aguilera A, Domingo P, Galindo MJ, Miralles C, Del Pozo MA, Ribera E, Iribarren JA, Ruiz L, de la Torre J, Vidal F, Clotet B, Albert J, Heidarian A, Aperia-Peipke K, Axelsson M, Mild M, Karlsson A, Sönnerborg A, Thalme A, Navér L, Bratt G, Karlsson A, Blaxhult A, Gisslén M, Svennerholm B, Bergbrant I, Björkman P, Säll C, Mellgren Å, Lindholm A, Kuylenstierna N, Montelius R, Azimi F, Johansson B, Carlsson M, Johansson E, Ljungberg B, Ekvall H, Strand A, Mäkitalo S, Öberg S, Holmblad P, Höfer M, Holmberg H, Josefson P, Ryding U.

Clin Infect Dis. 2016 Mar 1;62(5):655-663. doi: 10.1093/cid/civ963. Epub 2015 Nov 29.


Clinical outcome of maraviroc-containing therapy in heavily pre-treated HIV-1-infected patients.

van Lelyveld SF, Symons J, van Ham P, Connell BJ, Nijhuis M, Wensing AM, Hoepelman AI.

Int J Antimicrob Agents. 2016 Jan;47(1):84-90. doi: 10.1016/j.ijantimicag.2015.09.013. Epub 2015 Oct 25.


Comparison of digital PCR platforms and semi-nested qPCR as a tool to determine the size of the HIV reservoir.

Bosman KJ, Nijhuis M, van Ham PM, Wensing AM, Vervisch K, Vandekerckhove L, De Spiegelaere W.

Sci Rep. 2015 Sep 9;5:13811. doi: 10.1038/srep13811.


Treatment of Immunocompromised, Critically Ill Patients with Influenza A H1N1 Infection with a Combination of Oseltamivir, Amantadine, and Zanamivir.

Meijer WJ, Kromdijk W, van den Broek MP, Haas PJ, Minnema MC, Boucher CA, de Lange DW, Wensing AM.

Case Rep Infect Dis. 2015;2015:504975. doi: 10.1155/2015/504975. Epub 2015 Aug 9.


Maraviroc Intensification of cART in Patients with Suboptimal Immunological Recovery: A 48-Week, Placebo-Controlled Randomized Trial.

van Lelyveld SF, Drylewicz J, Krikke M, Veel EM, Otto SA, Richter C, Soetekouw R, Prins JM, Brinkman K, Mulder JW, Kroon F, Middel A, Symons J, Wensing AM, Nijhuis M, Borghans JA, Tesselaar K, Hoepelman AI; MIRS study group.

PLoS One. 2015 Jul 24;10(7):e0132430. doi: 10.1371/journal.pone.0132430. eCollection 2015.


Primary resistance to integrase strand-transfer inhibitors in Europe.

Casadellà M, van Ham PM, Noguera-Julian M, van Kessel A, Pou C, Hofstra LM, Santos JR, Garcia F, Struck D, Alexiev I, Bakken Kran AM, Hoepelman AI, Kostrikis LG, Somogyi S, Liitsola K, Linka M, Nielsen C, Otelea D, Paraskevis D, Poljak M, Puchhammer-Stöckl E, Staneková D, Stanojevic M, Van Laethem K, Zidovec Lepej S, Clotet B, Boucher CA, Paredes R, Wensing AM; SPREAD programme.

J Antimicrob Chemother. 2015 Oct;70(10):2885-8. doi: 10.1093/jac/dkv202. Epub 2015 Jul 17.


Combined Analysis of the Prevalence of Drug-Resistant Hepatitis B Virus in Antiviral Therapy-Experienced Patients in Europe (CAPRE).

Hermans LE, Svicher V, Pas SD, Salpini R, Alvarez M, Ben Ari Z, Boland G, Bruzzone B, Coppola N, Seguin-Devaux C, Dyda T, Garcia F, Kaiser R, Köse S, Krarup H, Lazarevic I, Lunar MM, Maylin S, Micheli V, Mor O, Paraschiv S, Paraskevis D, Poljak M, Puchhammer-Stöckl E, Simon F, Stanojevic M, Stene-Johansen K, Tihic N, Trimoulet P, Verheyen J, Vince A, Weis N, Yalcinkaya T, Lepej SZ, Perno C, Boucher CA, Wensing AM; HEPVIR Working Group of the European Society for Translational Antiviral Research.

J Infect Dis. 2016 Jan 1;213(1):39-48. doi: 10.1093/infdis/jiv363. Epub 2015 Jul 1.


Sufficient Immunosuppression with Thymoglobulin Is Essential for a Successful Haplo-Myeloid Bridge in Haploidentical-Cord Blood Transplantation.

Lindemans CA, Te Boome LC, Admiraal R, Jol-van der Zijde EC, Wensing AM, Versluijs AB, Bierings MB, Kuball J, Boelens JJ.

Biol Blood Marrow Transplant. 2015 Oct;21(10):1839-45. doi: 10.1016/j.bbmt.2015.06.001. Epub 2015 Jun 26.


Influenza virus infection in pregnancy: a review.

Meijer WJ, van Noortwijk AG, Bruinse HW, Wensing AM.

Acta Obstet Gynecol Scand. 2015 Aug;94(8):797-819. doi: 10.1111/aogs.12680. Epub 2015 Jun 13. Review.


Current knowledge and future perspectives on acute hepatitis C infection.

Hullegie SJ, Arends JE, Rijnders BJ, Irving WL, Salmon D, Prins M, Wensing AM, Klenerman P, Leblebicioglu H, Boesecke C, Rockstroh JK, Hoepelman AI.

Clin Microbiol Infect. 2015 Aug;21(8):797.e9-797.e17. doi: 10.1016/j.cmi.2015.03.026. Epub 2015 Apr 16. Review.


Acute otorrhea in children with tympanostomy tubes: prevalence of bacteria and viruses in the post-pneumococcal conjugate vaccine era.

van Dongen TM, Venekamp RP, Wensing AM, Bogaert D, Sanders EA, Schilder AG.

Pediatr Infect Dis J. 2015 Apr;34(4):355-60. doi: 10.1097/INF.0000000000000595.


Efficacy of tenofovir and efavirenz in combination with lamivudine or emtricitabine in antiretroviral-naive patients in Europe.

Swartz JE, Vandekerckhove L, Ammerlaan H, de Vries AC, Begovac J, Bierman WF, Boucher CA, van der Ende ME, Grossman Z, Kaiser R, Levy I, Mudrikova T, Paredes R, Perez-Bercoff D, Pronk M, Richter C, Schmit JC, Vercauteren J, Zazzi M, Židovec Lepej S, De Luca A, Wensing AM; European Society for translational Antiviral Research (ESAR).

J Antimicrob Chemother. 2015;70(6):1850-7. doi: 10.1093/jac/dkv033. Epub 2015 Mar 3.


Low HIV-1 transmitted drug resistance in Bulgaria against a background of high clade diversity.

Alexiev I, Shankar A, Wensing AM, Beshkov D, Elenkov I, Stoycheva M, Nikolova D, Nikolova M, Switzer WM.

J Antimicrob Chemother. 2015;70(6):1874-80. doi: 10.1093/jac/dkv011. Epub 2015 Feb 3.


Persistence of frequently transmitted drug-resistant HIV-1 variants can be explained by high viral replication capacity.

Pingen M, Wensing AM, Fransen K, De Bel A, de Jong D, Hoepelman AI, Magiorkinis E, Paraskevis D, Lunar MM, Poljak M, Nijhuis M, Boucher CA; SPREAD programme.

Retrovirology. 2014 Nov 29;11:105. doi: 10.1186/s12977-014-0105-9.


Global Dispersal Pattern of HIV Type 1 Subtype CRF01_AE: A Genetic Trace of Human Mobility Related to Heterosexual Sexual Activities Centralized in Southeast Asia.

Angelis K, Albert J, Mamais I, Magiorkinis G, Hatzakis A, Hamouda O, Struck D, Vercauteren J, Wensing AM, Alexiev I, Åsjö B, Balotta C, Camacho RJ, Coughlan S, Griskevicius A, Grossman Z, Horban A, Kostrikis LG, Lepej S, Liitsola K, Linka M, Nielsen C, Otelea D, Paredes R, Poljak M, Puchhammer-Stöckl E, Schmit JC, Sönnerborg A, Staneková D, Stanojevic M, Boucher CA, Kaplan L, Vandamme AM, Paraskevis D.

J Infect Dis. 2015 Jun 1;211(11):1735-44. doi: 10.1093/infdis/jiu666. Epub 2014 Dec 15.


Diminished transmission of drug resistant HIV-1 variants with reduced replication capacity in a human transmission model.

Pingen M, Sarrami-Forooshani R, Wensing AM, van Ham P, Drewniak A, Boucher CA, Geijtenbeek TB, Nijhuis M.

Retrovirology. 2014 Dec 14;11:113. doi: 10.1186/s12977-014-0113-9.


Residual viremia is preceding viral blips and persistent low-level viremia in treated HIV-1 patients.

Hofstra LM, Mudrikova T, Stam AJ, Otto S, Tesselaar K, Nijhuis M, Wensing AM.

PLoS One. 2014 Oct 29;9(10):e110749. doi: 10.1371/journal.pone.0110749. eCollection 2014.


Infection with the frequently transmitted HIV-1 M41L variant has no influence on selection of tenofovir resistance.

Pingen M, Nijhuis M, Mudrikova T, van Laarhoven A, Langebeek N, Richter C, Boucher CA, Wensing AM.

J Antimicrob Chemother. 2015 Feb;70(2):573-80. doi: 10.1093/jac/dku377. Epub 2014 Sep 26.


Increased prevalence of gastrointestinal viruses and diminished secretory immunoglobulin a levels in antibody deficiencies.

van de Ven AA, Janssen WJ, Schulz LS, van Loon AM, Voorkamp K, Sanders EA, Kusters JG, Nierkens S, Boes M, Wensing AM, van Montfrans JM.

J Clin Immunol. 2014 Nov;34(8):962-70. doi: 10.1007/s10875-014-0087-3. Epub 2014 Aug 19.


2014 Update of the drug resistance mutations in HIV-1.

Wensing AM, Calvez V, Günthard HF, Johnson VA, Paredes R, Pillay D, Shafer RW, Richman DD.

Top Antivir Med. 2014 Jun-Jul;22(3):642-50.


Increase in transmitted resistance to non-nucleoside reverse transcriptase inhibitors among newly diagnosed HIV-1 infections in Europe.

Frentz D, Van de Vijver DA, Abecasis AB, Albert J, Hamouda O, Jørgensen LB, Kücherer C, Struck D, Schmit JC, Vercauteren J, Åsjö B, Balotta C, Beshkov D, Camacho RJ, Clotet B, Coughlan S, Griskevicius A, Grossman Z, Horban A, Kolupajeva T, Korn K, Kostrikis LG, Liitsola K, Linka M, Nielsen C, Otelea D, Paraskevis D, Paredes R, Poljak M, Puchhammer-Stöckl E, Sönnerborg A, Stanekova D, Stanojevic M, Van Wijngaerden E, Wensing AM, Boucher CA; SPREAD Programme.

BMC Infect Dis. 2014 Jul 21;14:407. doi: 10.1186/1471-2334-14-407.


Dependence on the CCR5 coreceptor for viral replication explains the lack of rebound of CXCR4-predicted HIV variants in the Berlin patient.

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