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Items: 1 to 50 of 189

1.

Burn and thoracic trauma alters fracture healing, systemic inflammation, and leukocyte kinetics in a rat model of polytrauma.

Mangum LH, Avila JJ, Hurtgen BJ, Lofgren AL, Wenke JC.

J Orthop Surg Res. 2019 Feb 19;14(1):58. doi: 10.1186/s13018-019-1082-4.

2.

Recommendations for design and conduct of preclinical in vivo studies of orthopedic device-related infection.

Moriarty TF, Harris LG, Mooney RA, Wenke JC, Riool M, Zaat SAJ, Moter A, Schaer TP, Khanna N, Kuehl R, Alt V, Montali A, Liu J, Zeiter S, Busscher HJ, Grainger DW, Richards RG.

J Orthop Res. 2019 Feb;37(2):271-287. doi: 10.1002/jor.24230. Epub 2019 Feb 21. Review.

PMID:
30667561
3.
4.

Infection Precedes Heterotopic Ossification in Combat Wounded.

Juarez JK, Pugh MJ, Wenke JC, Rivera JC.

US Army Med Dep J. 2018 Jul-Dec;(2-18):1-5.

PMID:
30623392
5.

Poly(Thioketal Urethane) Autograft Extenders in an Intertransverse Process Model of Bone Formation.

McGough MAP, Shiels SM, Boller LA, Zienkiewicz KJ, Duvall CL, Wenke JC, Guelcher SA.

Tissue Eng Part A. 2019 Jan 9. doi: 10.1089/ten.TEA.2018.0223. [Epub ahead of print]

PMID:
30398387
6.

Topical rifampin powder for orthopaedic trauma part II: Topical rifampin allows for spontaneous bone healing in sterile and contaminated wounds.

Shiels SM, Tennent DJ, Lofgren AL, Wenke JC.

J Orthop Res. 2018 Dec;36(12):3142-3150. doi: 10.1002/jor.24155. Epub 2018 Oct 29.

PMID:
30270538
7.

Rapid degradation and non-selectivity of Dakin's solution prevents effectiveness in contaminated musculoskeletal wound models.

Mangum LC, Franklin NA, Garcia GR, Akers KS, Wenke JC.

Injury. 2018 Oct;49(10):1763-1773. doi: 10.1016/j.injury.2018.08.004. Epub 2018 Aug 6.

8.

Settable polymer/ceramic composite bone grafts stabilize weight-bearing tibial plateau slot defects and integrate with host bone in an ovine model.

Lu S, McGough MAP, Shiels SM, Zienkiewicz KJ, Merkel AR, Vanderburgh JP, Nyman JS, Sterling JA, Tennent DJ, Wenke JC, Guelcher SA.

Biomaterials. 2018 Oct;179:29-45. doi: 10.1016/j.biomaterials.2018.06.032. Epub 2018 Jun 26.

PMID:
29960822
9.

Topical rifampin powder for orthopedic trauma part I: Rifampin powder reduces recalcitrant infection in a delayed treatment musculoskeletal trauma model.

Shiels SM, Tennent DJ, Wenke JC.

J Orthop Res. 2018 Dec;36(12):3136-3141. doi: 10.1002/jor.24055. Epub 2018 Oct 5.

PMID:
29781552
10.

Current therapies in treatment and prevention of fracture wound biofilms: why a multifaceted approach is essential for resolving persistent infections.

Blanchette KA, Wenke JC.

J Bone Jt Infect. 2018 Apr 12;3(2):50-67. doi: 10.7150/jbji.23423. eCollection 2018. Review.

11.

Treatments and Preventative Measures for Trauma-Induced Heterotopic Ossification: A Review.

Juarez JK, Wenke JC, Rivera JC.

Clin Transl Sci. 2018 Jul;11(4):365-370. doi: 10.1111/cts.12552. Epub 2018 Apr 26. Review. No abstract available.

12.

Antibiotic Treatment - What Can Be Learned from Point of Injury Experience?

Benov A, Antebi B, Wenke JC, Batchinsky AI, Murray CK, Nachman D, Haim P, Tarif B, Glassberg E, Yitzhak A.

Mil Med. 2018 Mar 1;183(suppl_1):466-471. doi: 10.1093/milmed/usx144.

PMID:
29635557
13.

Chlorhexidine-releasing implant coating on intramedullary nail reduces infection in a rat model.

Shiels SM, Bouchard M, Wang H, Wenke JC.

Eur Cell Mater. 2018 Mar 22;35:178-194. doi: 10.22203/eCM.v035a13.

14.

Local control of polymicrobial infections via a dual antibiotic delivery system.

Tennent DJ, Shiels SM, Jennings JA, Haggard WO, Wenke JC.

J Orthop Surg Res. 2018 Mar 15;13(1):53. doi: 10.1186/s13018-018-0760-y.

15.

Risk of Obtaining Routine Cultures During Presumed Aseptic Orthopaedic Procedures.

Napierala MA, Bellamy JL, Murray CK, Hurley RK Jr, Wenke JC, Hsu JR.

J Surg Orthop Adv. 2017 WINTER;26(4):239-245.

PMID:
29461197
16.

Fresh whole blood resuscitation does not exacerbate skeletal muscle edema and long-term functional deficit after ischemic injury and hemorrhagic shock.

Aurora A, Roe JL, Umoh NA, Dubick M, Wenke JC, Walters TJ.

J Trauma Acute Care Surg. 2018 May;84(5):786-794. doi: 10.1097/TA.0000000000001806.

PMID:
29370063
17.

Tacrolimus as an adjunct to autologous minced muscle grafts for the repair of a volumetric muscle loss injury.

Corona BT, Rivera JC, Wenke JC, Greising SM.

J Exp Orthop. 2017 Nov 10;4(1):36. doi: 10.1186/s40634-017-0112-6.

18.

Determining potential of PMMA as a depot for rifampin to treat recalcitrant orthopaedic infections.

Shiels SM, Tennent DJ, Akers KS, Wenke JC.

Injury. 2017 Oct;48(10):2095-2100. doi: 10.1016/j.injury.2017.08.021. Epub 2017 Aug 16.

PMID:
28842287
19.

Autologous minced muscle grafts improve endogenous fracture healing and muscle strength after musculoskeletal trauma.

Hurtgen BJ, Ward CL, Leopold Wager CM, Garg K, Goldman SM, Henderson BEP, McKinley TO, Greising SM, Wenke JC, Corona BT.

Physiol Rep. 2017 Jul;5(14). pii: e13362. doi: 10.14814/phy2.13362.

20.

An Effective Negative Pressure Wound Therapy-Compatible Local Antibiotic Delivery Device.

Rand BCC, Wenke JC.

J Orthop Trauma. 2017 Dec;31(12):631-635. doi: 10.1097/BOT.0000000000000988.

PMID:
28742785
21.

Injectable and compression-resistant low-viscosity polymer/ceramic composite carriers for rhBMP-2 in a rabbit model of posterolateral fusion: a pilot study.

Shiels SM, Talley AD, McGough MAP, Zienkiewicz KJ, Kalpakci K, Shimko D, Guelcher SA, Wenke JC.

J Orthop Surg Res. 2017 Jul 11;12(1):107. doi: 10.1186/s13018-017-0613-0.

22.

Antibiotic-loaded bone graft for reduction of surgical site infection in spinal fusion.

Shiels SM, Raut VP, Patterson PB, Barnes BR, Wenke JC.

Spine J. 2017 Dec;17(12):1917-1925. doi: 10.1016/j.spinee.2017.06.039. Epub 2017 Jul 3.

PMID:
28684346
23.

Impairment of early fracture healing by skeletal muscle trauma is restored by FK506.

Hurtgen BJ, Henderson BEP, Ward CL, Goldman SM, Garg K, McKinley TO, Greising SM, Wenke JC, Corona BT.

BMC Musculoskelet Disord. 2017 Jun 12;18(1):253. doi: 10.1186/s12891-017-1617-y.

24.

Resorbable Nanocomposites with Bone-Like Strength and Enhanced Cellular Activity.

Lu S, McEnery MAP, Rogers BR, Wenke JC, Shimko D, Guelcher SA.

J Mater Chem B. 2017 Jun 14;5(22):4198-4206. doi: 10.1039/c7tb00657h. Epub 2017 May 11.

25.

Inhibition of fracture healing in the presence of contamination by Staphylococcus aureus: Effects of growth state and immune response.

Blanchette KA, Prabhakara R, Shirtliff ME, Wenke JC.

J Orthop Res. 2017 Sep;35(9):1845-1854. doi: 10.1002/jor.23573. Epub 2017 May 3. Review.

26.

Assessment of Severe Extremity Wound Bioburden at the Time of Definitive Wound Closure or Coverage: Correlation With Subsequent Postclosure Deep Wound Infection (Bioburden Study).

Bosse MJ, Murray CK, Carlini AR, Firoozabadi R, Manson T, Scharfstein DO, Wenke JC, Zadnik M, Castillo RC; METRC.

J Orthop Trauma. 2017 Apr;31 Suppl 1:S3-S9. doi: 10.1097/BOT.0000000000000805. Erratum in: J Orthop Trauma. 2017 Sep;31(9):e307.

PMID:
28323795
27.

Natural polymeric hydrogel evaluation for skeletal muscle tissue engineering.

Pollot BE, Rathbone CR, Wenke JC, Guda T.

J Biomed Mater Res B Appl Biomater. 2018 Feb;106(2):672-679. doi: 10.1002/jbm.b.33859. Epub 2017 Mar 17.

PMID:
28306190
28.

Military and Civilian Collaboration: The Power of Numbers.

Stinner DJ, Wenke JC, Ficke JR, Gordon W, Toledano J, Carlini AR, Scharfstein DO, MacKenzie EJ, Bosse MJ, Hsu JR; Major Extremity Trauma Research Consortium (METRC).

Mil Med. 2017 Mar;182(S1):10-17. doi: 10.7205/MILMED-D-16-00138.

PMID:
28291446
29.

The Highest-Impact Combat Orthopedic and Extremity Injury Articles in the Past 70 Years: A Citation Analysis.

Nam J, Do WS, Stinner DJ, Wenke JC, Orman JA, Kragh JF Jr.

J Spec Oper Med. Spring 2017;17(1):55-66.

PMID:
28285481
30.

Effects of Local Antibiotic Delivery from Porous Space Maintainers on Infection Clearance and Induction of an Osteogenic Membrane in an Infected Bone Defect.

Shah SR, Smith BT, Tatara AM, Molina ER, Lee EJ, Piepergerdes TC, Uhrig BA, Guldberg RE, Bennett GN, Wenke JC, Mikos AG.

Tissue Eng Part A. 2017 Feb;23(3-4):91-100. doi: 10.1089/ten.TEA.2016.0389. Epub 2017 Jan 11.

31.

Oxidatively Degradable Poly(thioketal urethane)/Ceramic Composite Bone Cements with Bone-Like Strength.

McEnery MA, Lu S, Gupta MK, Zienkiewicz KJ, Wenke JC, Kalpakci KN, Shimko D, Duvall CL, Guelcher SA.

RSC Adv. 2016;6(111):109414-109424. Epub 2016 Nov 8.

32.

Activity of Norspermidine on Bacterial Biofilms of Multidrug-Resistant Clinical Isolates Associated with Persistent Extremity Wound Infections.

Cardile AP, Woodbury RL, Sanchez CJ Jr, Becerra SC, Garcia RA, Mende K, Wenke JC, Akers KS.

Adv Exp Med Biol. 2017;973:53-70. doi: 10.1007/5584_2016_93.

33.

Pathophysiology of Volumetric Muscle Loss Injury.

Corona BT, Wenke JC, Ward CL.

Cells Tissues Organs. 2016;202(3-4):180-188. Epub 2016 Nov 9. Review.

PMID:
27825160
34.

Open Fracture Care During War: Opportunities for Research.

Rivera JC, Wenke JC, Pugh MJ.

JBJS Rev. 2016 Oct 25;4(10). pii: 01874474-201610000-00003. doi: 10.2106/JBJS.RVW.15.00105.

PMID:
27792675
35.

Analysis of injury patterns and roles of care in US and Israel militaries during recent conflicts: Two are better than one.

Antebi B, Benov A, Mann-Salinas EA, Le TD, Cancio LC, Wenke JC, Paran H, Yitzhak A, Tarif B, Gross KR, Dagan D, Glassberg E.

J Trauma Acute Care Surg. 2016 Nov;81(5 Suppl 2 Proceedings of the 2015 Military Health System Research Symposium):S87-S94.

PMID:
27602905
36.

Decellularized extracellular matrix repair of volumetric muscle loss injury impairs adjacent bone healing in a rat model of complex musculoskeletal trauma.

Pollot BE, Goldman SM, Wenke JC, Corona BT.

J Trauma Acute Care Surg. 2016 Nov;81(5 Suppl 2 Proceedings of the 2015 Military Health System Research Symposium):S184-S190.

PMID:
27533905
37.

Debridement and Irrigation: Evolution and Current Recommendations.

Erdle NJ, Verwiebe EG, Wenke JC, Smith CS.

J Orthop Trauma. 2016 Oct;30 Suppl 3:S7-S10.

PMID:
27661426
38.

In Vitro activity of Manuka Honey and polyhexamethylene biguanide on filamentous fungi and toxicity to human cell lines.

Yabes JM, White BK, Murray CK, Sanchez CJ, Mende K, Beckius ML, Zera WC, Wenke JC, Akers KS.

Med Mycol. 2017 Apr 1;55(3):334-343. doi: 10.1093/mmy/myw070.

39.

Military Orthopaedic Trauma Registry: Quality Data Now Available.

Rivera JC, Greer RM, Wenke JC, Ficke JR, Johnson AE.

J Surg Orthop Adv. 2016 summer;25(2):89-92.

PMID:
27518292
40.

Antibiotic-loaded bone void filler accelerates healing in a femoral condylar rat model.

Shiels SM, Cobb RR, Bedigrew KM, Ritter G, Kirk JF, Kimbler A, Finger Baker I, Wenke JC.

Bone Joint J. 2016 Aug;98-B(8):1126-31. doi: 10.1302/0301-620X.98B8.37634.

PMID:
27482028
41.

Autologous Minced Muscle Grafts Improve Muscle Strength in a Porcine Model of Volumetric Muscle Loss Injury.

Ward CL, Pollot BE, Goldman SM, Greising SM, Wenke JC, Corona BT.

J Orthop Trauma. 2016 Dec;30(12):e396-e403.

PMID:
27466826
42.

Severe muscle trauma triggers heightened and prolonged local musculoskeletal inflammation and impairs adjacent tibia fracture healing.

Hurtgen BJ, Ward CL, Garg K, Pollot BE, Goldman SM, McKinley TO, Wenke JC, Corona BT.

J Musculoskelet Neuronal Interact. 2016 Jun 1;16(2):122-34.

43.

Time-Dependent Effectiveness of Locally Applied Vancomycin Powder in a Contaminated Traumatic Orthopaedic Wound Model.

Tennent DJ, Shiels SM, Sanchez CJ Jr, Niece KL, Akers KS, Stinner DJ, Wenke JC.

J Orthop Trauma. 2016 Oct;30(10):531-7. doi: 10.1097/BOT.0000000000000617.

PMID:
27124826
44.

Activity of Gallium Meso- and Protoporphyrin IX against Biofilms of Multidrug-Resistant Acinetobacter baumannii Isolates.

Chang D, Garcia RA, Akers KS, Mende K, Murray CK, Wenke JC, Sanchez CJ.

Pharmaceuticals (Basel). 2016 Mar 17;9(1). pii: E16. doi: 10.3390/ph9010016.

45.

An In Vitro Comparison of PMMA and Calcium Sulfate as Carriers for the Local Delivery of Gallium(III) Nitrate to Staphylococcal Infected Surgical Sites.

Garcia RA, Tennent DJ, Chang D, Wenke JC, Sanchez CJ Jr.

Biomed Res Int. 2016;2016:7078989. doi: 10.1155/2016/7078989. Epub 2016 Jan 17.

46.

Volumetric muscle loss leads to permanent disability following extremity trauma.

Corona BT, Rivera JC, Owens JG, Wenke JC, Rathbone CR.

J Rehabil Res Dev. 2015;52(7):785-92. doi: 10.1682/JRRD.2014.07.0165.

47.

Combat-related bridge synostosis versus traditional transtibial amputation: comparison of military-specific outcomes.

Plucknette BF, Krueger CA, Rivera JC, Wenke JC.

Strategies Trauma Limb Reconstr. 2016 Apr;11(1):5-11. doi: 10.1007/s11751-015-0240-4. Epub 2015 Dec 7.

48.

Combined local and systemic antibiotic delivery improves eradication of wound contamination: An animal experimental model of contaminated fracture.

Rand BC, Penn-Barwell JG, Wenke JC.

Bone Joint J. 2015 Oct;97-B(10):1423-7. doi: 10.1302/0301-620X.97B10.35651.

PMID:
26430020
49.

Fresh frozen plasma reduces edema in skeletal muscle following combined limb ischemia-reperfusion injury and hemorrhagic shock in rats.

Kendrick CL, Edens JW, Christy RJ, Dubick MA, Wade CE, Holcomb JB, Wenke JC, Walters TJ.

J Trauma Acute Care Surg. 2015 Oct;79(4 Suppl 2):S110-5. doi: 10.1097/TA.0000000000000752.

PMID:
26406422
50.

Development of a hematogenous implant-related infection in a rat model.

Shiels SM, Bedigrew KM, Wenke JC.

BMC Musculoskelet Disord. 2015 Sep 14;16:255. doi: 10.1186/s12891-015-0699-7.

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