Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 36

1.

The antimicrobial potential of Streptomyces from insect microbiomes.

Chevrette MG, Carlson CM, Ortega HE, Thomas C, Ananiev GE, Barns KJ, Book AJ, Cagnazzo J, Carlos C, Flanigan W, Grubbs KJ, Horn HA, Hoffmann FM, Klassen JL, Knack JJ, Lewin GR, McDonald BR, Muller L, Melo WGP, Pinto-Tomás AA, Schmitz A, Wendt-Pienkowski E, Wildman S, Zhao M, Zhang F, Bugni TS, Andes DR, Pupo MT, Currie CR.

Nat Commun. 2019 Jan 31;10(1):516. doi: 10.1038/s41467-019-08438-0.

2.

Competition among nasal bacteria suggests a role for siderophore-mediated interactions in shaping the human nasal microbiota.

Stubbendieck RM, May DS, Chevrette MG, Temkin MI, Wendt-Pienkowski E, Cagnazzo J, Carlson CM, Gern JE, Currie CR.

Appl Environ Microbiol. 2018 Dec 21. pii: AEM.02406-18. doi: 10.1128/AEM.02406-18. [Epub ahead of print]

PMID:
30578265
3.

Evolution of High Cellulolytic Activity in Symbiotic Streptomyces through Selection of Expanded Gene Content and Coordinated Gene Expression.

Book AJ, Lewin GR, McDonald BR, Takasuka TE, Wendt-Pienkowski E, Doering DT, Suh S, Raffa KF, Fox BG, Currie CR.

PLoS Biol. 2016 Jun 8;14(6):e1002475. doi: 10.1371/journal.pbio.1002475. eCollection 2016 Jun.

4.

BlmB and TlmB provide resistance to the bleomycin family of antitumor antibiotics by N-acetylating metal-free bleomycin, tallysomycin, phleomycin, and zorbamycin.

Coughlin JM, Rudolf JD, Wendt-Pienkowski E, Wang L, Unsin C, Galm U, Yang D, Tao M, Shen B.

Biochemistry. 2014 Nov 11;53(44):6901-9. doi: 10.1021/bi501121e. Epub 2014 Oct 23.

5.

Cloning and sequencing of the kedarcidin biosynthetic gene cluster from Streptoalloteichus sp. ATCC 53650 revealing new insights into biosynthesis of the enediyne family of antitumor antibiotics.

Lohman JR, Huang SX, Horsman GP, Dilfer PE, Huang T, Chen Y, Wendt-Pienkowski E, Shen B.

Mol Biosyst. 2013 Mar;9(3):478-91. doi: 10.1039/c3mb25523a. Epub 2013 Jan 29.

6.

A designer bleomycin with significantly improved DNA cleavage activity.

Huang SX, Feng Z, Wang L, Galm U, Wendt-Pienkowski E, Yang D, Tao M, Coughlin JM, Duan Y, Shen B.

J Am Chem Soc. 2012 Aug 15;134(32):13501-9. doi: 10.1021/ja3056535. Epub 2012 Aug 6.

7.

Dedicated ent-kaurene and ent-atiserene synthases for platensimycin and platencin biosynthesis.

Smanski MJ, Yu Z, Casper J, Lin S, Peterson RM, Chen Y, Wendt-Pienkowski E, Rajski SR, Shen B.

Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13498-503. doi: 10.1073/pnas.1106919108. Epub 2011 Aug 8.

8.

Comparative analysis of the biosynthetic gene clusters and pathways for three structurally related antitumor antibiotics: bleomycin, tallysomycin, and zorbamycin.

Galm U, Wendt-Pienkowski E, Wang L, Huang SX, Unsin C, Tao M, Coughlin JM, Shen B.

J Nat Prod. 2011 Mar 25;74(3):526-36. doi: 10.1021/np1008152. Epub 2011 Jan 6. Review.

9.

Characterization of FdmV as an amide synthetase for fredericamycin A biosynthesis in Streptomyces griseus ATCC 43944.

Chen Y, Wendt-Pienkowski E, Ju J, Lin S, Rajski SR, Shen B.

J Biol Chem. 2010 Dec 10;285(50):38853-60. doi: 10.1074/jbc.M110.147744. Epub 2010 Oct 6.

10.

Oxazolomycin biosynthesis in Streptomyces albus JA3453 featuring an "acyltransferase-less" type I polyketide synthase that incorporates two distinct extender units.

Zhao C, Coughlin JM, Ju J, Zhu D, Wendt-Pienkowski E, Zhou X, Wang Z, Shen B, Deng Z.

J Biol Chem. 2010 Jun 25;285(26):20097-108. doi: 10.1074/jbc.M109.090092. Epub 2010 Apr 20.

11.

Functional characterization of tlmH in Streptoalloteichus hindustanus E465-94 ATCC 31158 unveiling new insight into tallysomycin biosynthesis and affording a novel bleomycin analog.

Tao M, Wang L, Wendt-Pienkowski E, Zhang N, Yang D, Galm U, Coughlin JM, Xu Z, Shen B.

Mol Biosyst. 2010 Feb;6(2):349-56. doi: 10.1039/b918106g. Epub 2009 Dec 1.

12.

Nosiheptide biosynthesis featuring a unique indole side ring formation on the characteristic thiopeptide framework.

Yu Y, Duan L, Zhang Q, Liao R, Ding Y, Pan H, Wendt-Pienkowski E, Tang G, Shen B, Liu W.

ACS Chem Biol. 2009 Oct 16;4(10):855-64. doi: 10.1021/cb900133x.

13.

The biosynthetic gene cluster of zorbamycin, a member of the bleomycin family of antitumor antibiotics, from Streptomyces flavoviridis ATCC 21892.

Galm U, Wendt-Pienkowski E, Wang L, George NP, Oh TJ, Yi F, Tao M, Coughlin JM, Shen B.

Mol Biosyst. 2009 Jan;5(1):77-90. doi: 10.1039/b814075h. Epub 2008 Nov 12.

14.

In vivo manipulation of the bleomycin biosynthetic gene cluster in Streptomyces verticillus ATCC15003 revealing new insights into its biosynthetic pathway.

Galm U, Wang L, Wendt-Pienkowski E, Yang R, Liu W, Tao M, Coughlin JM, Shen B.

J Biol Chem. 2008 Oct 17;283(42):28236-45. doi: 10.1074/jbc.M804971200. Epub 2008 Aug 12.

15.
16.

Identification of fredericamycin E from Streptomyces griseus: Insights into fredericamycin A biosynthesis highlighting carbaspirocycle formation.

Chen Y, Luo Y, Ju J, Wendt-Pienkowski E, Rajski SR, Shen B.

J Nat Prod. 2008 Mar;71(3):431-7. doi: 10.1021/np070664n. Epub 2008 Jan 31.

PMID:
18232659
17.

Characterization of the maduropeptin biosynthetic gene cluster from Actinomadura madurae ATCC 39144 supporting a unifying paradigm for enediyne biosynthesis.

Van Lanen SG, Oh TJ, Liu W, Wendt-Pienkowski E, Shen B.

J Am Chem Soc. 2007 Oct 31;129(43):13082-94. Epub 2007 Oct 6.

18.

Glycopeptide antitumor antibiotic zorbamycin from Streptomyces flavoviridis ATCC 21892: strain improvement and structure elucidation.

Wang L, Yun BS, George NP, Wendt-Pienkowski E, Galm U, Oh TJ, Coughlin JM, Zhang G, Tao M, Shen B.

J Nat Prod. 2007 Mar;70(3):402-6. Epub 2007 Feb 21.

19.

The tallysomycin biosynthetic gene cluster from Streptoalloteichus hindustanus E465-94 ATCC 31158 unveiling new insights into the biosynthesis of the bleomycin family of antitumor antibiotics.

Tao M, Wang L, Wendt-Pienkowski E, George NP, Galm U, Zhang G, Coughlin JM, Shen B.

Mol Biosyst. 2007 Jan;3(1):60-74. Epub 2006 Nov 28.

PMID:
17216057
20.

A dedicated phosphopantetheinyl transferase for the fredericamycin polyketide synthase from Streptomyces griseus.

Huang Y, Wendt-Pienkowski E, Shen B.

J Biol Chem. 2006 Oct 6;281(40):29660-8. Epub 2006 Aug 8.

21.

Cloning, sequencing, analysis, and heterologous expression of the fredericamycin biosynthetic gene cluster from Streptomyces griseus.

Wendt-Pienkowski E, Huang Y, Zhang J, Li B, Jiang H, Kwon H, Hutchinson CR, Shen B.

J Am Chem Soc. 2005 Nov 30;127(47):16442-52.

PMID:
16305230
22.

Prerequisites for combinatorial biosynthesis: evolution of hybrid NRPS/PKS gene clusters.

Shen B, Chen M, Cheng Y, Du L, Edwards DJ, George NP, Huang Y, Oh T, Sanchez C, Tang G, Wendt-Pienkowski E, Yi F.

Ernst Schering Res Found Workshop. 2005;(51):107-26. Review. No abstract available.

PMID:
15645718
23.

Rapid PCR amplification of minimal enediyne polyketide synthase cassettes leads to a predictive familial classification model.

Liu W, Ahlert J, Gao Q, Wendt-Pienkowski E, Shen B, Thorson JS.

Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):11959-63. Epub 2003 Oct 3.

24.
25.

An acyl-coenzyme A carboxylase encoding gene associated with jadomycin biosynthesis in Streptomyces venezuelae ISP5230.

Han L, Yang K, Kulowski K, Wendt-Pienkowski E, Hutchinson CR, Vining LC.

Microbiology. 2000 Apr;146 ( Pt 4):903-10.

PMID:
10784049
26.

The Streptomyces peucetius dpsC gene determines the choice of starter unit in biosynthesis of the daunorubicin polyketide.

Bao W, Sheldon PJ, Wendt-Pienkowski E, Hutchinson CR.

J Bacteriol. 1999 Aug;181(15):4690-5.

27.

Reconstitution of the iterative type II polyketide synthase for tetracenomycin F2 biosynthesis.

Bao W, Wendt-Pienkowski E, Hutchinson CR.

Biochemistry. 1998 Jun 2;37(22):8132-8.

PMID:
9609708
28.
29.

Sequencing and mutagenesis of genes from the erythromycin biosynthetic gene cluster of Saccharopolyspora erythraea that are involved in L-mycarose and D-desosamine production.

Summers RG, Donadio S, Staver MJ, Wendt-Pienkowski E, Hutchinson CR, Katz L.

Microbiology. 1997 Oct;143 ( Pt 10):3251-62.

PMID:
9353926
30.
33.

The genetic and biochemical basis of polyketide metabolism in microorganisms and its role in drug discovery and development.

Hutchinson CR, Borell CW, Donovan MJ, Kato F, Motamedi H, Nakayama H, Rubin RL, Streicher SL, Summers RG, Wendt-Pienkowski E, Wessel WL.

Planta Med. 1991 Oct;57(7 Suppl):S36-43.

PMID:
17226221
34.

The genetic and biochemical basis of polyketide metabolism in microorganisms and its role in drug discovery and development.

Hutchinson CR, Borell CW, Donovan MJ, Kato F, Motamedi H, Nakayama H, Rubin RL, Streicher SL, Summers RG, Wendt-Pienkowski E, et al.

Planta Med. 1991 Oct;57(7):S36-43. Review.

PMID:
1956956
35.

Isolation of tetracenomycin C-nonproducing Streptomyces glaucescens mutants.

Motamedi H, Wendt-Pienkowski E, Hutchinson CR.

J Bacteriol. 1986 Aug;167(2):575-80.

36.

Anthracycline metabolites of tetracenomycin C-nonproducing Streptomyces glaucescens mutants.

Yue S, Motamedi H, Wendt-Pienkowski E, Hutchinson CR.

J Bacteriol. 1986 Aug;167(2):581-6.

Supplemental Content

Loading ...
Support Center