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Items: 1 to 50 of 378

1.

Application of totarol as natural antibacterial coating on dental implants for prevention of peri-implantitis.

Xu Z, Krajewski S, Weindl T, Loeffler R, Li P, Han X, Geis-Gerstorfer J, Wendel HP, Scheideler L, Rupp F.

Mater Sci Eng C Mater Biol Appl. 2020 May;110:110701. doi: 10.1016/j.msec.2020.110701. Epub 2020 Jan 28.

PMID:
32204015
2.

Hemocompatibility Testing of Blood-Contacting Implants in a Flow Loop Model Mimicking Human Blood Flow.

Link A, Cattaneo G, Brynda E, Riedel T, Kucerova J, Schlensak C, Wendel HP, Krajewski S, Michel T.

J Vis Exp. 2020 Mar 5;(157). doi: 10.3791/60610.

PMID:
32202530
3.

Toward a Long-Term Artificial Lung.

Arens J, Grottke O, Haverich A, Maier LS, Schmitz-Rode T, Steinseifer U, Wendel HP, Rossaint R.

ASAIO J. 2020 Feb 25. doi: 10.1097/MAT.0000000000001139. [Epub ahead of print]

PMID:
32134795
4.

Multi-Modal Characterization of the Coagulopathy Associated With Extracorporeal Membrane Oxygenation.

Granja T, Hohenstein K, Schüssel P, Fischer C, Prüfer T, Schibilsky D, Wendel HP, Jaschonek K, Serna-Higuita L, Schlensak C, Häberle H, Rosenberger P, Straub A.

Crit Care Med. 2020 Feb 28. doi: 10.1097/CCM.0000000000004286. [Epub ahead of print]

PMID:
32118700
5.

iPSC-Derived MSCs Versus Originating Jaw Periosteal Cells: Comparison of Resulting Phenotype and Stem Cell Potential.

Umrath F, Weber M, Reinert S, Wendel HP, Avci-Adali M, Alexander D.

Int J Mol Sci. 2020 Jan 16;21(2). pii: E587. doi: 10.3390/ijms21020587.

6.

Comparison of broad-spectrum antiviral activities of the synthetic rocaglate CR-31-B (-) and the eIF4A-inhibitor Silvestrol.

Müller C, Obermann W, Schulte FW, Lange-Grünweller K, Oestereich L, Elgner F, Glitscher M, Hildt E, Singh K, Wendel HG, Hartmann RK, Ziebuhr J, Grünweller A.

Antiviral Res. 2020 Mar;175:104706. doi: 10.1016/j.antiviral.2020.104706. Epub 2020 Jan 10.

PMID:
31931103
7.

Application of Piezo-Based Measuring System for Evaluation of Nucleic Acid-Based Drugs Influencing the Coagulation.

Kunnakattu SJ, Hann L, Kurz J, Haag H, Fennrich S, Rauch N, Schlensak C, Wendel HP, Stoppelkamp S, Avci-Adali M.

Sensors (Basel). 2019 Dec 25;20(1). pii: E152. doi: 10.3390/s20010152.

8.

O-GlcNAcase targets pyruvate kinase M2 to regulate tumor growth.

Singh JP, Qian K, Lee JS, Zhou J, Han X, Zhang B, Ong Q, Ni W, Jiang M, Ruan HB, Li MD, Zhang K, Ding Z, Lee P, Singh K, Wu J, Herzog RI, Kaech S, Wendel HG, Yates JR 3rd, Han W, Sherwin RS, Nie Y, Yang X.

Oncogene. 2020 Jan;39(3):560-573. doi: 10.1038/s41388-019-0975-3. Epub 2019 Sep 9.

PMID:
31501520
9.

Reprogramming of Urine-Derived Renal Epithelial Cells into iPSCs Using srRNA and Consecutive Differentiation into Beating Cardiomyocytes.

Steinle H, Weber M, Behring A, Mau-Holzmann U, von Ohle C, Popov AF, Schlensak C, Wendel HP, Avci-Adali M.

Mol Ther Nucleic Acids. 2019 Sep 6;17:907-921. doi: 10.1016/j.omtn.2019.07.016. Epub 2019 Jul 31.

10.

The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase.

Sanghvi VR, Leibold J, Mina M, Mohan P, Berishaj M, Li Z, Miele MM, Lailler N, Zhao C, de Stanchina E, Viale A, Akkari L, Lowe SW, Ciriello G, Hendrickson RC, Wendel HG.

Cell. 2019 Aug 8;178(4):807-819.e21. doi: 10.1016/j.cell.2019.07.031.

PMID:
31398338
11.

Generation of iPSCs by Nonintegrative RNA-Based Reprogramming Techniques: Benefits of Self-Replicating RNA versus Synthetic mRNA.

Steinle H, Weber M, Behring A, Mau-Holzmann U, Schlensak C, Wendel HP, Avci-Adali M.

Stem Cells Int. 2019 Jun 19;2019:7641767. doi: 10.1155/2019/7641767. eCollection 2019.

12.

Noncovalent inhibitors reveal BTK gatekeeper and auto-inhibitory residues that control its transforming activity.

Wang S, Mondal S, Zhao C, Berishaj M, Ghanakota P, Batlevi CL, Dogan A, Seshan VE, Abel R, Green MR, Younes A, Wendel HG.

JCI Insight. 2019 Jun 20;4(12). pii: 127566. doi: 10.1172/jci.insight.127566. eCollection 2019 Jun 20.

13.

Efficient reduction of synthetic mRNA induced immune activation by simultaneous delivery of B18R encoding mRNA.

Michel T, Golombek S, Steinle H, Hann L, Velic A, Macek B, Krajewski S, Schlensak C, Wendel HP, Avci-Adali M.

J Biol Eng. 2019 May 9;13:40. doi: 10.1186/s13036-019-0172-5. eCollection 2019.

14.

In vitro investigation of chemical properties and biocompatibility of neurovascular braided implants.

Cattaneo G, Bräuner C, Siekmeyer G, Ding A, Bauer S, Wohlschlögel M, Lang L, Hierlemann T, Akimov M, Schlensak C, Schüßler A, Wendel HP, Krajewski S.

J Mater Sci Mater Med. 2019 Jun 4;30(6):67. doi: 10.1007/s10856-019-6270-6.

PMID:
31165278
15.

Hemocompatibility of different burn wound dressings.

Denzinger M, Held M, Scheffler H, Haag H, Nussler AK, Wendel HP, Schlensak C, Daigeler A, Krajewski S.

Wound Repair Regen. 2019 Sep;27(5):470-476. doi: 10.1111/wrr.12739. Epub 2019 Jun 13.

PMID:
31145535
16.

c-MYC regulates mRNA translation efficiency and start-site selection in lymphoma.

Singh K, Lin J, Zhong Y, Burčul A, Mohan P, Jiang M, Sun L, Yong-Gonzalez V, Viale A, Cross JR, Hendrickson RC, Rätsch G, Ouyang Z, Wendel HG.

J Exp Med. 2019 Jul 1;216(7):1509-1524. doi: 10.1084/jem.20181726. Epub 2019 May 29.

17.

Generation of iPSCs from Jaw Periosteal Cells Using Self-Replicating RNA.

Umrath F, Steinle H, Weber M, Wendel HP, Reinert S, Alexander D, Avci-Adali M.

Int J Mol Sci. 2019 Apr 3;20(7). pii: E1648. doi: 10.3390/ijms20071648.

18.

Exogenous Delivery of Link N mRNA into Chondrocytes and MSCs-The Potential Role in Increasing Anabolic Response.

Tendulkar G, Ehnert S, Sreekumar V, Chen T, Kaps HP, Golombek S, Wendel HP, Nüssler AK, Avci-Adali M.

Int J Mol Sci. 2019 Apr 6;20(7). pii: E1716. doi: 10.3390/ijms20071716.

19.

GPRC5D is a target for the immunotherapy of multiple myeloma with rationally designed CAR T cells.

Smith EL, Harrington K, Staehr M, Masakayan R, Jones J, Long TJ, Ng KY, Ghoddusi M, Purdon TJ, Wang X, Do T, Pham MT, Brown JM, De Larrea CF, Olson E, Peguero E, Wang P, Liu H, Xu Y, Garrett-Thomson SC, Almo SC, Wendel HG, Riviere I, Liu C, Sather B, Brentjens RJ.

Sci Transl Med. 2019 Mar 27;11(485). pii: eaau7746. doi: 10.1126/scitranslmed.aau7746.

PMID:
30918115
20.

Hyaluronic acid/poly(ethylenimine) polyelectrolyte multilayer coatings for siRNA-mediated local gene silencing.

Koenig O, Neumann B, Schlensak C, Wendel HP, Nolte A.

PLoS One. 2019 Mar 19;14(3):e0212584. doi: 10.1371/journal.pone.0212584. eCollection 2019.

21.

Emerging epigenetic-modulating therapies in lymphoma.

Sermer D, Pasqualucci L, Wendel HG, Melnick A, Younes A.

Nat Rev Clin Oncol. 2019 Aug;16(8):494-507. doi: 10.1038/s41571-019-0190-8. Review.

22.

Hemostatic wound dressings: Predicting their effects by in vitro tests.

Wiegand C, Abel M, Hipler UC, Elsner P, Zieger M, Kurz J, Wendel HP, Stoppelkamp S.

J Biomater Appl. 2019 Apr;33(9):1285-1297. doi: 10.1177/0885328219831095. Epub 2019 Feb 21.

PMID:
30791851
23.

Generation of Cationic Nanoliposomes for the Efficient Delivery of In Vitro Transcribed Messenger RNA.

Michel T, Link A, Abraham MK, Schlensak C, Peter K, Wendel HP, Wang X, Krajewski S.

J Vis Exp. 2019 Feb 1;(144). doi: 10.3791/58444.

PMID:
30774119
24.

Anaphylatoxin Receptor C3aR Contributes to Platelet Function, Thrombus Formation and In Vivo Haemostasis.

Sauter RJ, Sauter M, Obrich M, Emschermann FN, Nording H, Patzelt J, Wendel HP, Reil JC, Edlich F, Langer HF.

Thromb Haemost. 2019 Jan;119(1):179-182. doi: 10.1055/s-0038-1676349. Epub 2018 Dec 31.

PMID:
30597512
25.

Inflammatory potential of cotton-based surgically invasive devices: Implications for cardiac surgery.

Trunk S, Müllerbader P, Hennig U, Abel M, Koggel A, Stang K, Altreuter Y, Steger V, Schlensak C, Wendel HP, Stoppelkamp S.

J Biomed Mater Res B Appl Biomater. 2019 Aug;107(6):1877-1888. doi: 10.1002/jbm.b.34280. Epub 2018 Nov 22.

PMID:
30467962
26.

Panobinostat acts synergistically with ibrutinib in diffuse large B cell lymphoma cells with MyD88 L265P mutations.

Mondello P, Brea EJ, De Stanchina E, Toska E, Chang AY, Fennell M, Seshan V, Garippa R, Scheinberg DA, Baselga J, Wendel HG, Younes A.

JCI Insight. 2018 Nov 15;3(22). pii: 125568. doi: 10.1172/jci.insight.125568. No abstract available.

27.

NOXA genetic amplification or pharmacologic induction primes lymphoma cells to BCL2 inhibitor-induced cell death.

Liu Y, Mondello P, Erazo T, Tannan NB, Asgari Z, de Stanchina E, Nanjangud G, Seshan VE, Wang S, Wendel HG, Younes A.

Proc Natl Acad Sci U S A. 2018 Nov 20;115(47):12034-12039. doi: 10.1073/pnas.1806928115. Epub 2018 Nov 7.

28.

Keratinocyte Growth Factor Modified Messenger RNA Accelerating Cell Proliferation and Migration of Keratinocytes.

Denzinger M, Link A, Kurz J, Krauss S, Thoma R, Schlensak C, Wendel HP, Krajewski S.

Nucleic Acid Ther. 2018 Dec;28(6):335-347. doi: 10.1089/nat.2018.0737. Epub 2018 Oct 30.

PMID:
30376406
29.

Epicardial adhesion prophylaxis in swine model with a bio-absorbable polymer membrane.

Lescan M, Al-Saidi A, Neumann B, Greiner TO, Walker T, Hierlemann H, Brochhausen C, Planck H, Wendel HP, Schlensak C, Lausberg H.

J Mater Sci Mater Med. 2018 Oct 22;29(11):157. doi: 10.1007/s10856-018-6173-y. No abstract available.

PMID:
30350230
30.

Improving the Angiogenic Potential of EPCs via Engineering with Synthetic Modified mRNAs.

Steinle H, Golombek S, Behring A, Schlensak C, Wendel HP, Avci-Adali M.

Mol Ther Nucleic Acids. 2018 Dec 7;13:387-398. doi: 10.1016/j.omtn.2018.09.005. Epub 2018 Sep 13.

31.

EIF1AX and RAS Mutations Cooperate to Drive Thyroid Tumorigenesis through ATF4 and c-MYC.

Krishnamoorthy GP, Davidson NR, Leach SD, Zhao Z, Lowe SW, Lee G, Landa I, Nagarajah J, Saqcena M, Singh K, Wendel HG, Dogan S, Tamarapu PP, Blenis J, Ghossein RA, Knauf JA, Rätsch G, Fagin JA.

Cancer Discov. 2019 Feb;9(2):264-281. doi: 10.1158/2159-8290.CD-18-0606. Epub 2018 Oct 10.

32.

Blood-Contacting Biomaterials: In Vitro Evaluation of the Hemocompatibility.

Weber M, Steinle H, Golombek S, Hann L, Schlensak C, Wendel HP, Avci-Adali M.

Front Bioeng Biotechnol. 2018 Jul 16;6:99. doi: 10.3389/fbioe.2018.00099. eCollection 2018. Review.

33.

Development, preclinical evaluation and validation of a novel quick vascular closure device for transluminal, cardiac and radiological arterial catheterization.

Linti C, Doser M, Planck H, Oberhoffner S, Mueller E, Renardy M, Biesinger J, Neumann B, Stang K, Greiner TO, Schlensak C, Krajewski S, Wendel HP.

J Mater Sci Mater Med. 2018 Jun 11;29(6):83. doi: 10.1007/s10856-018-6092-y.

PMID:
29892952
34.

Clinical and Biological Correlates of Neurotoxicity Associated with CAR T-cell Therapy in Patients with B-cell Acute Lymphoblastic Leukemia.

Santomasso BD, Park JH, Salloum D, Riviere I, Flynn J, Mead E, Halton E, Wang X, Senechal B, Purdon T, Cross JR, Liu H, Vachha B, Chen X, DeAngelis LM, Li D, Bernal Y, Gonen M, Wendel HG, Sadelain M, Brentjens RJ.

Cancer Discov. 2018 Aug;8(8):958-971. doi: 10.1158/2159-8290.CD-17-1319. Epub 2018 Jun 7.

35.

De Novo Synthesis of Elastin by Exogenous Delivery of Synthetic Modified mRNA into Skin and Elastin-Deficient Cells.

Lescan M, Perl RM, Golombek S, Pilz M, Hann L, Yasmin M, Behring A, Keller T, Nolte A, Gruhn F, Kochba E, Levin Y, Schlensak C, Wendel HP, Avci-Adali M.

Mol Ther Nucleic Acids. 2018 Jun 1;11:475-484. doi: 10.1016/j.omtn.2018.03.013. Epub 2018 Mar 30.

36.

Intradermal Delivery of Synthetic mRNA Using Hollow Microneedles for Efficient and Rapid Production of Exogenous Proteins in Skin.

Golombek S, Pilz M, Steinle H, Kochba E, Levin Y, Lunter D, Schlensak C, Wendel HP, Avci-Adali M.

Mol Ther Nucleic Acids. 2018 Jun 1;11:382-392. doi: 10.1016/j.omtn.2018.03.005. Epub 2018 Mar 14.

37.

Incorporation of Synthetic mRNA in Injectable Chitosan-Alginate Hybrid Hydrogels for Local and Sustained Expression of Exogenous Proteins in Cells.

Steinle H, Ionescu TM, Schenk S, Golombek S, Kunnakattu SJ, Özbek MT, Schlensak C, Wendel HP, Avci-Adali M.

Int J Mol Sci. 2018 Apr 27;19(5). pii: E1313. doi: 10.3390/ijms19051313.

38.

QCM-D surpassing clinical standard for the dose administration of new oral anticoagulant in the patient of coagulation disorders.

Hussain M, Wendel HP, Schmidt K, Langer E, Körber MK, Faul O, Northoff H, von Heymann C, Gehring FK.

Biosens Bioelectron. 2018 May 1;104:15-20. doi: 10.1016/j.bios.2017.12.043. Epub 2017 Dec 27.

PMID:
29294406
39.

Biodegradable rifampicin-releasing coating of surgical meshes for the prevention of bacterial infections.

Reinbold J, Hierlemann T, Urich L, Uhde AK, Müller I, Weindl T, Vogel U, Schlensak C, Wendel HP, Krajewski S.

Drug Des Devel Ther. 2017 Sep 18;11:2753-2762. doi: 10.2147/DDDT.S138510. eCollection 2017.

40.

Nanoliposomes for Safe and Efficient Therapeutic mRNA Delivery: A Step Toward Nanotheranostics in Inflammatory and Cardiovascular Diseases as well as Cancer.

Abraham MK, Peter K, Michel T, Wendel HP, Krajewski S, Wang X.

Nanotheranostics. 2017 Apr 5;1(2):154-165. doi: 10.7150/ntno.19449. eCollection 2017.

41.

Preventing Surgical Site Infections Using a Natural, Biodegradable, Antibacterial Coating on Surgical Sutures.

Reinbold J, Uhde AK, Müller I, Weindl T, Geis-Gerstorfer J, Schlensak C, Wendel HP, Krajewski S.

Molecules. 2017 Sep 19;22(9). pii: E1570. doi: 10.3390/molecules22091570.

42.

Cationic Nanoliposomes Meet mRNA: Efficient Delivery of Modified mRNA Using Hemocompatible and Stable Vectors for Therapeutic Applications.

Michel T, Luft D, Abraham MK, Reinhardt S, Salinas Medina ML, Kurz J, Schaller M, Avci-Adali M, Schlensak C, Peter K, Wendel HP, Wang X, Krajewski S.

Mol Ther Nucleic Acids. 2017 Sep 15;8:459-468. doi: 10.1016/j.omtn.2017.07.013. Epub 2017 Jul 25.

43.

Targeted PET imaging strategy to differentiate malignant from inflamed lymph nodes in diffuse large B-cell lymphoma.

Tang J, Salloum D, Carney B, Brand C, Kossatz S, Sadique A, Lewis JS, Weber WA, Wendel HG, Reiner T.

Proc Natl Acad Sci U S A. 2017 Sep 5;114(36):E7441-E7449. doi: 10.1073/pnas.1705013114. Epub 2017 Aug 21.

44.

Effect of Immobilized Antithrombin III on the Thromboresistance of Polycarbonate Urethane.

Lukas K, Stadtherr K, Gessner A, Wehner D, Schmid T, Wendel HP, Schmid C, Lehle K.

Materials (Basel). 2017 Mar 24;10(4). pii: E335. doi: 10.3390/ma10040335.

45.

Evaluation of platelet adhesion and activation on polymers: Round-robin study to assess inter-center variability.

Braune S, Sperling C, Maitz MF, Steinseifer U, Clauser J, Hiebl B, Krajewski S, Wendel HP, Jung F.

Colloids Surf B Biointerfaces. 2017 Oct 1;158:416-422. doi: 10.1016/j.colsurfb.2017.06.053. Epub 2017 Jul 3.

PMID:
28719863
46.

Genetic and epigenetic inactivation of SESTRIN1 controls mTORC1 and response to EZH2 inhibition in follicular lymphoma.

Oricchio E, Katanayeva N, Donaldson MC, Sungalee S, Pasion JP, Béguelin W, Battistello E, Sanghvi VR, Jiang M, Jiang Y, Teater M, Parmigiani A, Budanov AV, Chan FC, Shah SP, Kridel R, Melnick AM, Ciriello G, Wendel HG.

Sci Transl Med. 2017 Jun 28;9(396). pii: eaak9969. doi: 10.1126/scitranslmed.aak9969.

47.

Low-thrombogenic fibrin-heparin coating promotes in vitro endothelialization.

Kaplan O, Hierlemann T, Krajewski S, Kurz J, Nevoralová M, Houska M, Riedel T, Riedelová Z, Zárubová J, Wendel HP, Brynda E.

J Biomed Mater Res A. 2017 Nov;105(11):2995-3005. doi: 10.1002/jbm.a.36152. Epub 2017 Aug 7.

PMID:
28646555
48.

Rapid Complexation of Aptamers by Their Specific Antidotes.

Stoll H, Steinle H, Wilhelm N, Hann L, Kunnakattu SJ, Narita M, Schlensak C, Wendel HP, Avci-Adali M.

Molecules. 2017 Jun 8;22(6). pii: E954. doi: 10.3390/molecules22060954.

49.

Catheter-based tricuspid valve replacement: first experimental data of a newly designed bileaflet stent graft prosthesis.

Lausberg HF, Gryszkiewicz R, Kuetting M, Baumgaertner M, Centola M, Wendel HP, Nowak-Machen M, Schibilsky D, Kruger T, Schlensak C.

Eur J Cardiothorac Surg. 2017 Jul 1;52(1):189-196. doi: 10.1093/ejcts/ezx084.

PMID:
28430904
50.

Panobinostat acts synergistically with ibrutinib in diffuse large B cell lymphoma cells with MyD88 L265P mutations.

Mondello P, Brea EJ, De Stanchina E, Toska E, Chang AY, Fennell M, Seshan V, Garippa R, Scheinberg DA, Baselga J, Wendel HG, Younes A.

JCI Insight. 2017 Mar 23;2(6):e90196. doi: 10.1172/jci.insight.90196. Erratum in: JCI Insight. 2018 Nov 15;3(22):.

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