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Items: 1 to 50 of 1645

1.

Degradation of ronidazole by electrochemically simultaneously generated persulfate and ferrous ions.

Si F, Zhang Y, Yao C, Du M, Hussain I, Huang S, Wen W, Hu X.

Chemosphere. 2019 Aug 12;238:124579. doi: 10.1016/j.chemosphere.2019.124579. [Epub ahead of print]

PMID:
31434045
2.

Optic disc shape in patients with long-lasting unilateral esotropia and exotropia.

Shang K, Dai Y, Liu H, Qu X, Wen W, Jonas JB.

BMC Ophthalmol. 2019 Aug 16;19(1):185. doi: 10.1186/s12886-019-1197-8.

3.

The Prognostic Value of the MiR-200 Family in Colorectal Cancer: A Meta-analysis with 1882 Patients.

Yu C, Wan H, Shan R, Wen W, Li J, Luo D, Wan R.

J Cancer. 2019 Jul 8;10(17):4009-4016. doi: 10.7150/jca.27529. eCollection 2019.

4.

Systematic Review and Meta-Analysis of Randomized Controlled Trials on the Effect of SGLT2 Inhibitor on Blood Leptin and Adiponectin Level in Patients with Type 2 Diabetes.

Wu P, Wen W, Li J, Xu J, Zhao M, Chen H, Sun J.

Horm Metab Res. 2019 Aug;51(8):487-494. doi: 10.1055/a-0958-2441. Epub 2019 Aug 13.

PMID:
31408894
5.

Identifying Putative Susceptibility Genes and Evaluating Their Associations with Somatic Mutations in Human Cancers.

Chen Z, Wen W, Beeghly-Fadiel A, Shu XO, Díez-Obrero V, Long J, Bao J, Wang J, Liu Q, Cai Q, Moreno V, Zheng W, Guo X.

Am J Hum Genet. 2019 Jul 26. pii: S0002-9297(19)30269-1. doi: 10.1016/j.ajhg.2019.07.006. [Epub ahead of print]

PMID:
31402092
6.

RELA Fusion in Supratentorial Extraventricular Ependymomas: A Morphologic, Immunohistochemical, and Molecular Study of 43 Cases.

Wang L, Liu L, Li H, Wang P, Hu Z, Wei Y, Zhang M, Wen W, Li Z, Liu L, Zhao L, Lu D, Teng L.

Am J Surg Pathol. 2019 Aug 6. doi: 10.1097/PAS.0000000000001342. [Epub ahead of print]

PMID:
31393268
7.

A novel label-free electrochemical impedance aptasensor for highly sensitive detection of human interferon-gamma based on target-induced exonuclease inhibition.

Li H, Song S, Wen M, Bao T, Wu Z, Xiong H, Zhang X, Wen W, Wang S.

Biosens Bioelectron. 2019 Jul 25;142:111532. doi: 10.1016/j.bios.2019.111532. [Epub ahead of print]

PMID:
31377576
8.

A subgraph-representation-based method for answering complex questions over knowledge bases.

Hao Z, Wu B, Wen W, Cai R.

Neural Netw. 2019 Jul 26;119:57-65. doi: 10.1016/j.neunet.2019.07.014. [Epub ahead of print]

PMID:
31376638
9.

GHz sampling hardware implementation with sub-Nyquist coprime sampling rates.

Wen W, Yan H, Zhao Y, Liu D, He H.

Rev Sci Instrum. 2019 Jul;90(7):074706. doi: 10.1063/1.5110266.

PMID:
31370498
10.

Synergistic effect of functionalized poly(l-lactide) with surface-modified MgO and chitin whiskers on osteogenesis in vivo and in vitro.

Liu W, Zou Z, Zhou L, Liu H, Wen W, Zhou C, Luo B.

Mater Sci Eng C Mater Biol Appl. 2019 Oct;103:109851. doi: 10.1016/j.msec.2019.109851. Epub 2019 Jun 3.

PMID:
31349474
11.

Construction of a flexible electrochemiluminescence platform for sweat detection.

Chen MM, Cheng SB, Ji K, Gao J, Liu YL, Wen W, Zhang X, Wang S, Huang WH.

Chem Sci. 2019 May 22;10(25):6295-6303. doi: 10.1039/c9sc01937e. eCollection 2019 Jul 7.

12.

Dental Care-Seeking and Information Acquisition During Pregnancy: A Qualitative Study.

Liu PP, Wen W, Yu KF, Gao X, Wong MCM.

Int J Environ Res Public Health. 2019 Jul 23;16(14). pii: E2621. doi: 10.3390/ijerph16142621.

13.

psbE-psbL and ndhA Intron, the Promising Plastid DNA Barcode of Fagopyrum.

Huang Y, Li Z, Wang C, Zou C, Wen W, Shao J, Zhu X.

Int J Mol Sci. 2019 Jul 14;20(14). pii: E3455. doi: 10.3390/ijms20143455.

14.

Cerebral Blood Flow in Community-Based Older Twins Is Moderately Heritable: An Arterial Spin Labeling Perfusion Imaging Study.

Jiang J, Thalamuthu A, Koch FC, Liu T, Xu Q, Trollor JN, Ames D, Wright MJ, Catts V, Sachdev PS, Wen W.

Front Aging Neurosci. 2019 Jul 2;11:169. doi: 10.3389/fnagi.2019.00169. eCollection 2019.

15.

Allergic sensitization in patients with rhinitis and bronchial asthma in Ningxia region of China.

Di LL, Wang LX, Ma X, Wen WL, Gao XP.

J Eval Clin Pract. 2019 Jul 22. doi: 10.1111/jep.13239. [Epub ahead of print]

PMID:
31332901
16.

Random Organic Nanolaser Arrays for Cryptographic Primitives.

Feng J, Wen W, Wei X, Jiang X, Cao M, Wang X, Zhang X, Jiang L, Wu Y.

Adv Mater. 2019 Jul 22:e1807880. doi: 10.1002/adma.201807880. [Epub ahead of print]

PMID:
31328840
17.

Systematic cancer-testis gene expression analysis identified CDCA5 as a potential therapeutic target in esophageal squamous cell carcinoma.

Xu J, Zhu C, Yu Y, Wu W, Cao J, Li Z, Dai J, Wang C, Tang Y, Zhu Q, Wang J, Wen W, Xue L, Zhen F, Liu J, Huang C, Zhao F, Zhou Y, He Z, Pan X, Wei H, Zhu Y, He Y, Que J, Luo J, Chen L, Wang W.

EBioMedicine. 2019 Aug;46:54-65. doi: 10.1016/j.ebiom.2019.07.030. Epub 2019 Jul 16.

18.

Differential gene expression and AKT targeting in triple negative breast cancer.

Lin FM, Yost SE, Wen W, Frankel PH, Schmolze D, Chu PG, Yuan YC, Liu Z, Yim J, Chen Z, Yuan Y.

Oncotarget. 2019 Jul 8;10(43):4356-4368. doi: 10.18632/oncotarget.27026. eCollection 2019 Jul 8.

19.

A multi-lock inhibitory mechanism for fine-tuning enzyme activities of the HECT family E3 ligases.

Wang Z, Liu Z, Chen X, Li J, Yao W, Huang S, Gu A, Lei QY, Mao Y, Wen W.

Nat Commun. 2019 Jul 18;10(1):3162. doi: 10.1038/s41467-019-11224-7.

20.

Facile Preparation of Hybrid Structure Based on Mesodome and Micropillar Arrays as Flexible Electronic Skin with Tunable Sensitivity and Detection Range.

Ji B, Mao Y, Zhou Q, Zhou J, Chen G, Gao Y, Tian Y, Wen W, Zhou B.

ACS Appl Mater Interfaces. 2019 Aug 7;11(31):28060-28071. doi: 10.1021/acsami.9b08419. Epub 2019 Jul 25.

PMID:
31306581
21.

Seneca Valley virus 2C and 3C inhibit type I interferon production by inducing the degradation of RIG-I.

Wen W, Yin M, Zhang H, Liu T, Chen H, Qian P, Hu J, Li X.

Virology. 2019 Jun 28;535:122-129. doi: 10.1016/j.virol.2019.06.017. [Epub ahead of print]

PMID:
31299488
22.

Does religious involvement affect mortality in low-income Americans? A prospective cohort study.

Wen W, Schlundt D, Andersen SW, Blot WJ, Zheng W.

BMJ Open. 2019 Jul 9;9(7):e028200. doi: 10.1136/bmjopen-2018-028200.

23.

Inhibition of breast cancer cells by targeting E2F-1 gene and expressing IL15 oncolytic adenovirus.

Yan Y, Xu H, Wang J, Wu X, Wen W, Liang Y, Wang L, Liu F, Du X.

Biosci Rep. 2019 Jul 23;39(7). pii: BSR20190384. doi: 10.1042/BSR20190384. Print 2019 Jul 31.

24.

Uptake pathway and accumulation of polycyclic aromatic hydrocarbons in spinach affected by warming in enclosed soil/water-air-plant microcosms.

Chen J, Xia X, Wang H, Zhai Y, Xi N, Lin H, Wen W.

J Hazard Mater. 2019 Jun 27;379:120831. doi: 10.1016/j.jhazmat.2019.120831. [Epub ahead of print]

PMID:
31271938
25.

Decreased neonatal hepatitis B virus (HBV) viremia by maternal tenofovir treatment predicts reduced chronic HBV infection in children born to highly viremic mothers.

Chang KC, Chang MH, Lee CN, Chang CH, Wu JF, Ni YH, Wen WH, Shyu MK, Lai MW, Chen SM, Hu JJ, Lin HH, Hsu JJ, Mu SC, Lin YC, Liu CJ, Chen DS, Lin LH, Chen HL; Taiwan Study Group for the Prevention of Mother-to-Infant Transmission of HBV (PreMIT study).

Aliment Pharmacol Ther. 2019 Aug;50(3):306-316. doi: 10.1111/apt.15321. Epub 2019 Jul 4.

PMID:
31271463
26.

Biomineralization guided by polydopamine-modifed poly(L-lactide) fibrous membrane for promoted osteoconductive activity.

Chen X, Zhu L, Liu H, Wen W, Li H, Zhou C, Luo B.

Biomed Mater. 2019 Jul 19;14(5):055005. doi: 10.1088/1748-605X/ab2f2d.

PMID:
31271155
27.

Epigenetic Modification of Enhancer of Zeste Homolog 2 Modulates the Activation of Dendritic Cells in Allergen Immunotherapy.

Li H, Wen Y, Wu S, Chen D, Luo X, Xu R, Ma R, Wen W.

Int Arch Allergy Immunol. 2019 Jun 28:1-8. doi: 10.1159/000500882. [Epub ahead of print]

PMID:
31256157
28.

Hollow copper sulfide nanocubes as multifunctional nanozymes for colorimetric detection of dopamine and electrochemical detection of glucose.

Zhu J, Peng X, Nie W, Wang Y, Gao J, Wen W, Selvaraj JN, Zhang X, Wang S.

Biosens Bioelectron. 2019 Jun 20;141:111450. doi: 10.1016/j.bios.2019.111450. [Epub ahead of print]

PMID:
31247454
29.

Corticosteroids and Regional Variations in Thickness of the Human Cerebral Cortex across the Lifespan.

Parker N, Vidal-Pineiro D, French L, Shin J, Adams HHH, Brodaty H, Cox SR, Deary IJ, Fjell AM, Frenzel S, Grabe H, Hosten N, Ikram MA, Jiang J, Knol MJ, Mazoyer B, Mishra A, Sachdev PS, Salum G, Satizabal CL, Schmidt H, Schmidt R, Seshadri S, Schumann G, Völzke H, Walhovd KB, Wen W, Wittfeld K, Yang Q, Debette S, Pausova Z, Paus T.

Cereb Cortex. 2019 Jun 26. pii: bhz108. doi: 10.1093/cercor/bhz108. [Epub ahead of print]

PMID:
31240317
30.

Silencing FUNDC1 alleviates chronic obstructive pulmonary disease by inhibiting mitochondrial autophagy and bronchial epithelium cell apoptosis under hypoxic environment.

Wen W, Yu G, Liu W, Gu L, Chu J, Zhou X, Liu Y, Lai G.

J Cell Biochem. 2019 Jun 25. doi: 10.1002/jcb.29028. [Epub ahead of print]

PMID:
31237014
31.

Crop Phenomics: Current Status and Perspectives.

Zhao C, Zhang Y, Du J, Guo X, Wen W, Gu S, Wang J, Fan J.

Front Plant Sci. 2019 Jun 3;10:714. doi: 10.3389/fpls.2019.00714. eCollection 2019. Review.

32.

Interferon-inducible cytoplasmic lncLrrc55-AS promotes antiviral innate responses by strengthening IRF3 phosphorylation.

Zhou Y, Li M, Xue Y, Li Z, Wen W, Liu X, Ma Y, Zhang L, Shen Z, Cao X.

Cell Res. 2019 Aug;29(8):641-654. doi: 10.1038/s41422-019-0193-0. Epub 2019 Jun 18.

PMID:
31213650
33.

Targeted therapy for hepatocellular carcinoma: Challenges and opportunities.

Chen S, Cao Q, Wen W, Wang H.

Cancer Lett. 2019 Sep 28;460:1-9. doi: 10.1016/j.canlet.2019.114428. Epub 2019 Jun 15.

PMID:
31207320
34.

Effect of pyrite on enhancement of zero-valent iron corrosion for arsenic removal in water: A mechanistic study.

Du M, Zhang Y, Hussain I, Du X, Huang S, Wen W.

Chemosphere. 2019 Oct;233:744-753. doi: 10.1016/j.chemosphere.2019.05.197. Epub 2019 May 25.

PMID:
31200134
35.

Effectiveness of Revive SE in the RAPID registry : Revive Acute Ischemic Stroke Patients ImmeDiately (RAPID) Prospective Multicenter Trial.

Zhang Y, Wen W, Chen C, Wu Z, Xiang X, Shi H, Guan S, Jiang G, Peng Y, Li Z, Li Z, Zhang L, Zhang Y, Hong B, Yang P, Liu J.

Clin Neuroradiol. 2019 Jun 7. doi: 10.1007/s00062-019-00798-w. [Epub ahead of print]

PMID:
31175375
36.

Does delay in feedback diminish sense of agency? A review.

Wen W.

Conscious Cogn. 2019 Aug;73:102759. doi: 10.1016/j.concog.2019.05.007. Epub 2019 Jun 4. Review.

PMID:
31173998
37.

Subwavelength topological edge states based on localized spoof surface plasmonic metaparticle arrays.

Wang L, Zhang RY, Hou B, Huang Y, Li S, Wen W.

Opt Express. 2019 May 13;27(10):14407-14422. doi: 10.1364/OE.27.014407.

PMID:
31163891
38.

Independent Severe Cases of Heterozygous Familial Hypercholesterolemia Caused by the W483X and Novel W483G Mutations in the Low-Density Lipoprotein Receptor Gene That Were Clinically Diagnosed as Homozygous Cases.

Cheng S, Wu Y, Wen W, An M, Gao Y, Wang L, Han X, Shang H.

Genet Test Mol Biomarkers. 2019 Jun;23(6):401-408. doi: 10.1089/gtmb.2019.0012.

PMID:
31161821
39.

Discovery of a Pathogenic Variant rs139379666 (p. P2974L) in ATM for Breast Cancer Risk in Chinese Populations.

Guo X, Lin W, Bai M, Li H, Wen W, Zeng C, Chen Z, He J, Chen J, Cai Q, Long J, Jia WH, Shu XO, Zheng W.

Cancer Epidemiol Biomarkers Prev. 2019 Aug;28(8):1308-1315. doi: 10.1158/1055-9965.EPI-18-1294. Epub 2019 Jun 3.

PMID:
31160347
40.

Identification of two microRNA signatures in whole blood as novel biomarkers for diagnosis of nasopharyngeal carcinoma.

Wen W, Mai SJ, Lin HX, Zhang MY, Huang JL, Hua X, Lin C, Long ZQ, Lu ZJ, Sun XQ, Liu SL, Yang Q, Zhu Q, Wang HY, Guo L.

J Transl Med. 2019 Jun 3;17(1):186. doi: 10.1186/s12967-019-1923-2.

41.

Comparison of long-term outcomes of young patients after a coronary event associated with familial hypercholesterolemia.

Wang X, Cai G, Wang Y, Liu R, Xi Z, Li G, Wen W, Wu Y, Wang C, Ji Q, Wang X, Zhang Q, Zeng Y, Wang L, Liu W, Zhou Y.

Lipids Health Dis. 2019 Jun 1;18(1):131. doi: 10.1186/s12944-019-1074-8.

42.

Fluorometric determination of copper(II) by using 3-aminophenylboronic acid-functionalized CdTe quantum dot probes.

Xiong H, Wang B, Wen W, Zhang X, Wang S.

Mikrochim Acta. 2019 May 31;186(6):392. doi: 10.1007/s00604-019-3515-5.

PMID:
31152237
43.

[Interpretation of the Japanese guidance for pediatric familial hypercholesterolemia 2017].

Wen WH, Wu WF, Wang X, Wu Y, Kuang ZM, Wang LY.

Zhonghua Xin Xue Guan Bing Za Zhi. 2019 May 24;47(5):417-420. doi: 10.3760/cma.j.issn.0253-3758.2019.05.018. Chinese.

PMID:
31142091
44.

Rapid, one-step preparation of SERS substrate in microfluidic channel for detection of molecules and heavy metal ions.

Yan S, Chu F, Zhang H, Yuan Y, Huang Y, Liu A, Wang S, Li W, Li S, Wen W.

Spectrochim Acta A Mol Biomol Spectrosc. 2019 Sep 5;220:117113. doi: 10.1016/j.saa.2019.05.018. Epub 2019 May 17.

PMID:
31141779
45.

Increasing Antitumor Activity of JAK Inhibitor by Simultaneous Blocking Multiple Survival Signaling Pathways in Human Ovarian Cancer.

Wen W, Han ES, Dellinger TH, Wu J, Guo Y, Buettner R, Horne DA, Jove R, Yim JH.

Transl Oncol. 2019 Aug;12(8):1015-1025. doi: 10.1016/j.tranon.2019.05.003. Epub 2019 May 26.

46.

Genome-wide variation patterns between landraces and cultivars uncover divergent selection during modern wheat breeding.

Liu J, Rasheed A, He Z, Imtiaz M, Arif A, Mahmood T, Ghafoor A, Siddiqui SU, Ilyas MK, Wen W, Gao F, Xie C, Xia X.

Theor Appl Genet. 2019 May 28. doi: 10.1007/s00122-019-03367-4. [Epub ahead of print]

PMID:
31139853
47.

[The effect of trabeculectomy combined with prophylactic sclerotomy as a treatment of late stage juvenile open angle glaucoma and primary congenital glaucoma patients: a primary observational study].

Chen YH, Wen W, Wu N, Ling ZH, Chen JY, Chen Q, Sun XH.

Zhonghua Yan Ke Za Zhi. 2019 May 11;55(5):347-354. doi: 10.3760/cma.j.issn.0412-4081.2019.05.008. Chinese.

PMID:
31137146
48.

Expression of Prostate-Specific Membrane Antigen in Tumor-Associated Vasculature Predicts Poor Prognosis in Hepatocellular Carcinoma.

Jiao D, Li Y, Yang F, Han D, Wu J, Shi S, Tian F, Guo Z, Xi W, Li G, Zhao A, Yang AG, Qin W, Wang H, Wen W.

Clin Transl Gastroenterol. 2019 May 15. doi: 10.14309/ctg.0000000000000041. [Epub ahead of print]

PMID:
31136358
49.

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.

Sung YJ, de Las Fuentes L, Winkler TW, Chasman DI, Bentley AR, Kraja AT, Ntalla I, Warren HR, Guo X, Schwander K, Manning AK, Brown MR, Aschard H, Feitosa MF, Franceschini N, Lu Y, Cheng CY, Sim X, Vojinovic D, Marten J, Musani SK, Kilpeläinen TO, Richard MA, Aslibekyan S, Bartz TM, Dorajoo R, Li C, Liu Y, Rankinen T, Smith AV, Tajuddin SM, Tayo BO, Zhao W, Zhou Y, Matoba N, Sofer T, Alver M, Amini M, Boissel M, Chai JF, Chen X, Divers J, Gandin I, Gao C, Giulianini F, Goel A, Harris SE, Hartwig FP, He M, Horimoto ARVR, Hsu FC, Jackson AU, Kammerer CM, Kasturiratne A, Komulainen P, Kühnel B, Leander K, Lee WJ, Lin KH, Luan J, Lyytikäinen LP, McKenzie CA, Nelson CP, Noordam R, Scott RA, Sheu WHH, Stančáková A, Takeuchi F, van der Most PJ, Varga TV, Waken RJ, Wang H, Wang Y, Ware EB, Weiss S, Wen W, Yanek LR, Zhang W, Zhao JH, Afaq S, Alfred T, Amin N, Arking DE, Aung T, Barr RG, Bielak LF, Boerwinkle E, Bottinger EP, Braund PS, Brody JA, Broeckel U, Cade B, Campbell A, Canouil M, Chakravarti A, Cocca M, Collins FS, Connell JM, de Mutsert R, de Silva HJ, Dörr M, Duan Q, Eaton CB, Ehret G, Evangelou E, Faul JD, Forouhi NG, Franco OH, Friedlander Y, Gao H, Gigante B, Gu CC, Gupta P, Hagenaars SP, Harris TB, He J, Heikkinen S, Heng CK, Hofman A, Howard BV, Hunt SC, Irvin MR, Jia Y, Katsuya T, Kaufman J, Kerrison ND, Khor CC, Koh WP, Koistinen HA, Kooperberg CB, Krieger JE, Kubo M, Kutalik Z, Kuusisto J, Lakka TA, Langefeld CD, Langenberg C, Launer LJ, Lee JH, Lehne B, Levy D, Lewis CE, Li Y; Lifelines Cohort Study, Lim SH, Liu CT, Liu J, Liu J, Liu Y, Loh M, Lohman KK, Louie T, Mägi R, Matsuda K, Meitinger T, Metspalu A, Milani L, Momozawa Y, Mosley TH Jr, Nalls MA, Nasri U, O'Connell JR, Ogunniyi A, Palmas WR, Palmer ND, Pankow JS, Pedersen NL, Peters A, Peyser PA, Polasek O, Porteous D, Raitakari OT, Renström F, Rice TK, Ridker PM, Robino A, Robinson JG, Rose LM, Rudan I, Sabanayagam C, Salako BL, Sandow K, Schmidt CO, Schreiner PJ, Scott WR, Sever P, Sims M, Sitlani CM, Smith BH, Smith JA, Snieder H, Starr JM, Strauch K, Tang H, Taylor KD, Teo YY, Tham YC, Uitterlinden AG, Waldenberger M, Wang L, Wang YX, Wei WB, Wilson G, Wojczynski MK, Xiang YB, Yao J, Yuan JM, Zonderman AB, Becker DM, Boehnke M, Bowden DW, Chambers JC, Chen YI, Weir DR, de Faire U, Deary IJ, Esko T, Farrall M, Forrester T, Freedman BI, Froguel P, Gasparini P, Gieger C, Horta BL, Hung YJ, Jonas JB, Kato N, Kooner JS, Laakso M, Lehtimäki T, Liang KW, Magnusson PKE, Oldehinkel AJ, Pereira AC, Perls T, Rauramaa R, Redline S, Rettig R, Samani NJ, Scott J, Shu XO, van der Harst P, Wagenknecht LE, Wareham NJ, Watkins H, Wickremasinghe AR, Wu T, Kamatani Y, Laurie CC, Bouchard C, Cooper RS, Evans MK, Gudnason V, Hixson J, Kardia SLR, Kritchevsky SB, Psaty BM, van Dam RM, Arnett DK, Mook-Kanamori DO, Fornage M, Fox ER, Hayward C, van Duijn CM, Tai ES, Wong TY, Loos RJF, Reiner AP, Rotimi CN, Bierut LJ, Zhu X, Cupples LA, Province MA, Rotter JI, Franks PW, Rice K, Elliott P, Caulfield MJ, Gauderman WJ, Munroe PB, Rao DC, Morrison AC.

Hum Mol Genet. 2019 Apr 10. pii: ddz070. doi: 10.1093/hmg/ddz070. [Epub ahead of print]

PMID:
31127295
50.

Expression of Prostate-Specific Membrane Antigen in Tumor-Associated Vasculature Predicts Poor Prognosis in Hepatocellular Carcinoma.

Jiao D, Li Y, Yang F, Han D, Wu J, Shi S, Tian F, Guo Z, Xi W, Li G, Zhao A, Yang AG, Qin W, Wang H, Wen W.

Clin Transl Gastroenterol. 2019 May 22;10(5):1-7. doi: 10.14309/ctg.0000000000000041.

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