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Items: 27


Role of LTBP4 in alveolarization, angiogenesis, and fibrosis in lungs.

Bultmann-Mellin I, Dinger K, Debuschewitz C, Loewe KMA, Melcher Y, Plum MTW, Appel S, Rappl G, Willenborg S, Schauss AC, Jüngst C, Krüger M, Dressler S, Nakamura T, Wempe F, Alejandre Alcázar MA, Sterner-Kock A.

Am J Physiol Lung Cell Mol Physiol. 2017 Oct 1;313(4):L687-L698. doi: 10.1152/ajplung.00031.2017. Epub 2017 Jul 6.


Cytochrome P450 enzymes but not NADPH oxidases are the source of the NADPH-dependent lucigenin chemiluminescence in membrane assays.

Rezende F, Prior KK, Löwe O, Wittig I, Strecker V, Moll F, Helfinger V, Schnütgen F, Kurrle N, Wempe F, Walter M, Zukunft S, Luck B, Fleming I, Weissmann N, Brandes RP, Schröder K.

Free Radic Biol Med. 2017 Jan;102:57-66. doi: 10.1016/j.freeradbiomed.2016.11.019. Epub 2016 Nov 15.


Ltbp4 regulates Pdgfrβ expression via TGFβ-dependent modulation of Nrf2 transcription factor function.

Tomasovic A, Kurrle N, Wempe F, De-Zolt S, Scheibe S, Koli K, Serchinger M, Schnütgen F, Sürün D, Sterner-Kock A, Weissmann N, von Melchner H.

Matrix Biol. 2017 May;59:109-120. doi: 10.1016/j.matbio.2016.09.006. Epub 2016 Sep 17.


Modeling autosomal recessive cutis laxa type 1C in mice reveals distinct functions for Ltbp-4 isoforms.

Bultmann-Mellin I, Conradi A, Maul AC, Dinger K, Wempe F, Wohl AP, Imhof T, Wunderlich FT, Bunck AC, Nakamura T, Koli K, Bloch W, Ghanem A, Heinz A, von Melchner H, Sengle G, Sterner-Kock A.

Dis Model Mech. 2015 Apr;8(4):403-15. doi: 10.1242/dmm.018960. Epub 2015 Feb 20.


Sestrin-2, a repressor of PDGFRβ signalling, promotes cigarette-smoke-induced pulmonary emphysema in mice and is upregulated in individuals with COPD.

Heidler J, Fysikopoulos A, Wempe F, Seimetz M, Bangsow T, Tomasovic A, Veit F, Scheibe S, Pichl A, Weisel F, Lloyd KC, Jaksch P, Klepetko W, Weissmann N, von Melchner H.

Dis Model Mech. 2013 Nov;6(6):1378-87. doi: 10.1242/dmm.013482. Epub 2013 Aug 29.


Severe combined immunodeficiency in Frisian Water Dogs caused by a RAG1 mutation.

Verfuurden B, Wempe F, Reinink P, van Kooten PJ, Martens E, Gerritsen R, Vos JH, Rutten VP, Leegwater PA.

Genes Immun. 2011 Jun;12(4):310-3. doi: 10.1038/gene.2011.6. Epub 2011 Feb 3.


Inactivation of sestrin 2 induces TGF-beta signaling and partially rescues pulmonary emphysema in a mouse model of COPD.

Wempe F, De-Zolt S, Koli K, Bangsow T, Parajuli N, Dumitrascu R, Sterner-Kock A, Weissmann N, Keski-Oja J, von Melchner H.

Dis Model Mech. 2010 Mar-Apr;3(3-4):246-53. doi: 10.1242/dmm.004234. Epub 2010 Jan 27.


Transcription factor PROX1 induces colon cancer progression by promoting the transition from benign to highly dysplastic phenotype.

Petrova TV, Nykänen A, Norrmén C, Ivanov KI, Andersson LC, Haglund C, Puolakkainen P, Wempe F, von Melchner H, Gradwohl G, Vanharanta S, Aaltonen LA, Saharinen J, Gentile M, Clarke A, Taipale J, Oliver G, Alitalo K.

Cancer Cell. 2008 May;13(5):407-19. doi: 10.1016/j.ccr.2008.02.020.


Proteasomal degradation of the multifunctional regulator YB-1 is mediated by an F-Box protein induced during programmed cell death.

Lutz M, Wempe F, Bahr I, Zopf D, von Melchner H.

FEBS Lett. 2006 Jul 10;580(16):3921-30. Epub 2006 Jun 21.


Disruption of LTBP-4 function reduces TGF-beta activation and enhances BMP-4 signaling in the lung.

Koli K, Wempe F, Sterner-Kock A, Kantola A, Komor M, Hofmann WK, von Melchner H, Keski-Oja J.

J Cell Biol. 2004 Oct 11;167(1):123-33. Epub 2004 Oct 4.


Disruption of the gene encoding the latent transforming growth factor-beta binding protein 4 (LTBP-4) causes abnormal lung development, cardiomyopathy, and colorectal cancer.

Sterner-Kock A, Thorey IS, Koli K, Wempe F, Otte J, Bangsow T, Kuhlmeier K, Kirchner T, Jin S, Keski-Oja J, von Melchner H.

Genes Dev. 2002 Sep 1;16(17):2264-73.


Gene trapping identifies transiently induced survival genes during programmed cell death.

Wempe F, Yang JY, Hammann J, von Melchner H.

Genome Biol. 2001;2(7):RESEARCH0023. Epub 2001 Jun 27.


Porcine luteal cells express monocyte chemoattractant protein-2 (MCP-2): analysis by cDNA cloning and northern analysis.

Hosang K, Knoke I, Klaudiny J, Wempe F, Wuttke W, Scheit KH.

Biochem Biophys Res Commun. 1994 Nov 30;205(1):148-53.


Characterization of the bovine monocyte chemoattractant protein-1 gene.

Wempe F, Kuhlmann JK, Scheit KH.

Biochem Biophys Res Commun. 1994 Aug 15;202(3):1272-9.


Porcine luteal cells express monocyte chemoattractant protein-1 (MCP-1): analysis by polymerase chain reaction and cDNA cloning.

Hosang K, Knoke I, Klaudiny J, Wempe F, Wuttke W, Scheit KH.

Biochem Biophys Res Commun. 1994 Mar 15;199(2):962-8.


Cloning of the gene for bovine monocyte chemoattractant protein-2.

Wempe F, Hanes J, Scheit KH.

DNA Cell Biol. 1994 Jan;13(1):1-8.


Characterization of a full-length cDNA encoding a bovine four tandem-repeat ubiquitin.

Wempe F, Scheit KH.

Biochim Biophys Acta. 1993 Feb 20;1172(1-2):209-11.


Characterization by cDNA cloning of the mRNA of a new growth factor from bovine seminal plasma: acidic seminal fluid protein.

Wempe F, Einspanier R, Scheit KH.

Biochem Biophys Res Commun. 1992 Feb 28;183(1):232-7.


Characterization of a new bioactive protein from bovine seminal fluid.

Einspanier R, Einspanier A, Wempe F, Scheit KH.

Biochem Biophys Res Commun. 1991 Sep 16;179(2):1006-10.


Characterization of three abundant mRNAs from human ovarian granulosa cells.

Rapp G, Freudenstein J, Klaudiny J, Mucha J, Wempe F, Zimmer M, Scheit KH.

DNA Cell Biol. 1990 Sep;9(7):479-85.


Seminalplasmin, the major basic protein of bull seminal plasma, is a secretory protein of the seminal vesicles.

Wempe F, Wagner S, vd Kammer H, Krauhs E, Scheit KH.

Biochim Biophys Acta. 1990 Jun 20;1034(3):260-2. Erratum in: Biochim Biophys Acta 1990 Oct 12;1036(1):83.


The effect of palmitate and lactate on mechanical performance and metabolism of cat and rat myocardium.

Drake-Holland AJ, Elzinga G, Noble MI, ter Keurs HE, Wempe FN.

J Physiol. 1983 Jun;339:1-15.


[Diagnostic value of 12-lead exertion electrocardiography following a heart infarct].

de Feyter PJ, van Eenige MJ, Majid PA, Wempe FN, Roos JP.

Ned Tijdschr Geneeskd. 1982 Mar 27;126(13):559-64. Dutch. No abstract available.


Clinical significance of exercise-induced ST segment elevation. Correlative angiographic study in patients with ischaemic heart disease.

de Feyter PJ, Majid PA, van Eenige MJ, Wardeh R, Wempe FN, Roos JP.

Br Heart J. 1981 Jul;46(1):84-92.

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