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Morphomolecular motifs of pulmonary neoangiogenesis in interstitial lung diseases.

Ackermann M, Stark H, Neubert L, Schubert S, Borchert P, Linz F, Wagner WL, Stiller W, Wielpütz M, Hoefer A, Haverich A, Mentzer SJ, Shah HR, Welte T, Kuehnel M, Jonigk D.

Eur Respir J. 2019 Dec 5. pii: 1900933. doi: 10.1183/13993003.00933-2019. [Epub ahead of print]


Generation of a NKX2.1 - p63 double transgenic knock-in reporter cell line from human induced pluripotent stem cells (MHHi006-A-4).

Drick N, Sahabian A, Pongpamorn P, Merkert S, Göhring G, Welte T, Martin U, Olmer R.

Stem Cell Res. 2019 Nov 19;42:101659. doi: 10.1016/j.scr.2019.101659. [Epub ahead of print]


Pneumococcal conjugate serotype distribution and predominating role of serotype 3 in German adults with community-acquired pneumonia.

Forstner C, Kolditz M, Kesselmeier M, Ewig S, Rohde G, Barten-Neiner G, Rupp J, Witzenrath M, Welte T, Pletz MW; CAPNETZ study group.

Vaccine. 2019 Nov 21. pii: S0264-410X(19)31549-X. doi: 10.1016/j.vaccine.2019.11.026. [Epub ahead of print]


CAT score single item analysis in patients with COPD: Results from COSYCONET.

Marietta von Siemens S, Alter P, Lutter JI, Kauczor HU, Jobst B, Bals R, Trudzinski FC, Söhler S, Behr J, Watz H, Waschki B, Bewig B, Jones PW, Welte T, Vogelmeier CF, Jörres RA, Kahnert K; COSYCONET study group; Names of participating study nurses.

Respir Med. 2019 Nov;159:105810. doi: 10.1016/j.rmed.2019.105810. Epub 2019 Nov 7.


Time-updated resting heart rate predicts mortality in patients with COPD.

Omlor AJ, Trudzinski FC, Alqudrah M, Seiler F, Biertz F, Vogelmeier CF, Welte T, Watz H, Waschki B, Brinker TJ, Andreas S, Fähndrich S, Alter P, Jörres RA, Böhm M, Bals R; German COSYCONET Cohort.

Clin Res Cardiol. 2019 Nov 16. doi: 10.1007/s00392-019-01572-1. [Epub ahead of print]


The association of cognitive functioning as measured by the DemTect with functional and clinical characteristics of COPD: results from the COSYCONET cohort.

von Siemens SM, Perneczky R, Vogelmeier CF, Behr J, Kauffmann-Guerrero D, Alter P, Trudzinski FC, Bals R, Grohé C, Söhler S, Waschki B, Lutter JI, Welte T, Jörres RA, Kahnert K; COSYCONET study group.

Respir Res. 2019 Nov 14;20(1):257. doi: 10.1186/s12931-019-1217-5.


Extracorporeal Membrane Oxygenation for Severe ARDS Due to Immune Diffuse Alveolar Hemorrhage: A Retrospective Observational Study.

Seeliger B, Stahl K, Schenk H, Schmidt JJ, Wiesner O, Welte T, Kuehn C, Bauersachs J, Hoeper MM, David S.

Chest. 2019 Nov 9. pii: S0012-3692(19)34128-5. doi: 10.1016/j.chest.2019.10.021. [Epub ahead of print] No abstract available.


Non-competitive binding of PpiD and YidC to the SecYEG translocon expands the global view on the SecYEG interactome in E. coli.

Jauß B, Petriman NA, Drepper F, Franz L, Sachelaru I, Welte T, Steinberg R, Warscheid B, Koch HG.

J Biol Chem. 2019 Nov 7. pii: jbc.RA119.010686. doi: 10.1074/jbc.RA119.010686. [Epub ahead of print]


Economic analysis of ceftaroline fosamil for treating community-acquired pneumonia in Spain.

Torres A, Bassetti M, Welte T, Rivolo S, Remak E, Peral C, Charbonneau C, Hammond J, Ansari W, Grau S.

J Med Econ. 2019 Nov 26:1-8. doi: 10.1080/13696998.2019.1688819. [Epub ahead of print]


Rate and Predictors of Bacteremia in Afebrile Community-Acquired Pneumonia.

Forstner C, Patchev V, Rohde G, Rupp J, Witzenrath M, Welte T, Burgmann H, Pletz MW; CAPNETZ Study Group.

Chest. 2019 Oct 26. pii: S0012-3692(19)34102-9. doi: 10.1016/j.chest.2019.10.006. [Epub ahead of print]


Maintenance Immunosuppression Is Associated With Better Outcome in the 2017/2018 Influenza Epidemic.

Stahl K, Seeliger B, Busch M, Wiesner O, Welte T, Eder M, Schäfer A, Bauersachs J, Haller H, Heim A, Hoeper MM, David S.

Open Forum Infect Dis. 2019 Sep 24;6(10):ofz381. doi: 10.1093/ofid/ofz381. eCollection 2019 Oct.


[What you can learn from viruses].

Welte T, Vogelmeier CF.

Internist (Berl). 2019 Nov;60(11):1125-1126. doi: 10.1007/s00108-019-00678-y. German. No abstract available.


Adherence To Respiratory And Nonrespiratory Medication In Patients With COPD: Results Of The German COSYCONET Cohort.

Königsdorfer N, Jörres RA, Söhler S, Welte T, Behr J, Ficker JH, Bals R, Watz H, Lutter JI, Lucke T, Biertz F, Alter P, Vogelmeier CF, Kahnert K.

Patient Prefer Adherence. 2019 Oct 10;13:1711-1721. doi: 10.2147/PPA.S223438. eCollection 2019.


Anti-IL5 and anti-IL5Rα therapy for clinically significant bronchiectasis with eosinophilic endotype: a case series.

Rademacher J, Konwert S, Fuge J, Dettmer S, Welte T, Ringshausen FC.

Eur Respir J. 2019 Oct 16. pii: 1901333. doi: 10.1183/13993003.01333-2019. [Epub ahead of print] No abstract available.


Invasive mould infections in solid organ transplant patients: modifiers and indicators of disease and treatment response.

Welte T, Len O, Muñoz P, Romani L, Lewis R, Perrella A.

Infection. 2019 Dec;47(6):919-927. doi: 10.1007/s15010-019-01360-z. Epub 2019 Oct 1. Review.


Macrolide combination therapy for hospitalised CAP patients? An individualised approach supported by machine learning.

König R, Cao X, Oswald M, Forstner C, Rohde G, Rupp J, Witzenrath M, Welte T, Kolditz M, Pletz M; CAPNETZ study group.

Eur Respir J. 2019 Sep 19. pii: 1900824. doi: 10.1183/13993003.00824-2019. [Epub ahead of print]


The ERS fellowship portfolio: fostering excellence and diversity.

Morty RE, Donnelly LE, Stolz D, Roche N, Welte T, Forrest KA, Brightling CE, Brusselle GG.

Eur Respir J. 2019 Sep 5;54(3). pii: 1901503. doi: 10.1183/13993003.01503-2019. Print 2019 Sep. No abstract available.


Clinical Significance of SERPINA1 Gene and Its Encoded Alpha1-antitrypsin Protein in NSCLC.

Ercetin E, Richtmann S, Delgado BM, Gomez-Mariano G, Wrenger S, Korenbaum E, Liu B, DeLuca D, Kühnel MP, Jonigk D, Yuskaeva K, Warth A, Muley T, Winter H, Meister M, Welte T, Janciauskiene S, Schneider MA.

Cancers (Basel). 2019 Sep 4;11(9). pii: E1306. doi: 10.3390/cancers11091306.


Increasing bronchiectasis prevalence in Germany, 2009-2017: a population-based cohort study.

Ringshausen FC, Rademacher J, Pink I, de Roux A, Hickstein L, Ploner T, Welte T, Diel R.

Eur Respir J. 2019 Dec 4;54(6). pii: 1900499. doi: 10.1183/13993003.00499-2019. Print 2019 Dec. No abstract available.


Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms.

Kim IS, Gao Y, Welte T, Wang H, Liu J, Janghorban M, Sheng K, Niu Y, Goldstein A, Zhao N, Bado I, Lo HC, Toneff MJ, Nguyen T, Bu W, Jiang W, Arnold J, Gu F, He J, Jebakumar D, Walker K, Li Y, Mo Q, Westbrook TF, Zong C, Rao A, Sreekumar A, Rosen JM, Zhang XH.

Nat Cell Biol. 2019 Sep;21(9):1113-1126. doi: 10.1038/s41556-019-0373-7. Epub 2019 Aug 26.


Morphological and molecular motifs of fibrosing pulmonary injury patterns.

Jonigk D, Stark H, Braubach P, Neubert L, Shin HO, Izykowski N, Welte T, Janciauskiene S, Warnecke G, Haverich A, Kuehnel M, Laenger F.

J Pathol Clin Res. 2019 Oct;5(4):256-271. doi: 10.1002/cjp2.141. Epub 2019 Sep 25.


Ceftaroline fosamil as a potential treatment option for Staphylococcus aureus community-acquired pneumonia in adults.

Welte T, Kantecki M, Stone GG, Hammond J.

Int J Antimicrob Agents. 2019 Oct;54(4):410-422. doi: 10.1016/j.ijantimicag.2019.08.012. Epub 2019 Aug 9. Review.


The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1.

Welte T, Tuck AC, Papasaikas P, Carl SH, Flemr M, Knuckles P, Rankova A, Bühler M, Großhans H.

Genes Dev. 2019 Sep 1;33(17-18):1221-1235. doi: 10.1101/gad.328492.119. Epub 2019 Aug 1.


Pleural Effusion in Adults-Etiology, Diagnosis, and Treatment.

Jany B, Welte T.

Dtsch Arztebl Int. 2019 May 24;116(21):377-386. doi: 10.3238/arztebl.2019.0377.


Consequences of chronic kidney disease in chronic obstructive pulmonary disease.

Trudzinski FC, Alqudrah M, Omlor A, Zewinger S, Fliser D, Speer T, Seiler F, Biertz F, Koch A, Vogelmeier C, Welte T, Watz H, Waschki B, Fähndrich S, Jörres R, Bals R; German COSYCONET consortium.

Respir Res. 2019 Jul 12;20(1):151. doi: 10.1186/s12931-019-1107-x.


SERPINA1 gene polymorphisms in a population-based ALSPAC cohort.

DeLuca DS, Poluzioroviene E, Taminskiene V, Wrenger S, Utkus A, Valiulis A, Alasevičius T, Henderson J, Bush A, Welte T, Janciauskiene S, Valiulis A.

Pediatr Pulmonol. 2019 Sep;54(9):1474-1478. doi: 10.1002/ppul.24422. Epub 2019 Jul 12.


Combined effects of lung function, blood gases and kidney function on the exacerbation risk in stable COPD: Results from the COSYCONET cohort.

Trudzinski FC, Kahnert K, Vogelmeier CF, Alter P, Seiler F, Fähndrich S, Watz H, Welte T, Speer T, Zewinger S, Biertz F, Kauczor HU, Jörres RA, Bals R; COSYCONET consortium.

Respir Med. 2019 Jul - Aug;154:18-26. doi: 10.1016/j.rmed.2019.06.007. Epub 2019 Jun 11.


PCR-based routine diagnostics uncover hidden burden of Legionnaires' disease.

Pletz MW, Ewig S, Welte T.

Lancet Infect Dis. 2019 Jul;19(7):681-683. doi: 10.1016/S1473-3099(19)30171-9. Epub 2019 Jun 10. No abstract available.


Left heart function in COPD : Impact of lung deflation.

Struß N, Bauersachs J, Welte T, Hohlfeld JM.

Herz. 2019 Sep;44(6):477-482. doi: 10.1007/s00059-019-4816-5.


Serum Levels of Alpha1-antitrypsin and Their Relationship With COPD in the General Spanish Population.

Janciauskiene S, DeLuca DS, Barrecheguren M, Welte T, Miravitlles M; Scientific Committee; Participating sites and coordinators.

Arch Bronconeumol. 2019 May 30. pii: S0300-2896(19)30112-7. doi: 10.1016/j.arbres.2019.03.001. [Epub ahead of print] English, Spanish.


Extracorporeal membrane oxygenation for acute respiratory distress syndrome due to Pneumocystis pneumonia.

Stahl K, Schenk H, Seeliger B, Wiesner O, Schmidt JJ, Bauersachs J, Welte T, Kühn C, Haverich A, Hoeper MM, David S.

Eur Respir J. 2019 Sep 19;54(3). pii: 1900410. doi: 10.1183/13993003.00410-2019. Print 2019 Sep. No abstract available.


MRI-derived regional flow-volume loop parameters detect early-stage chronic lung allograft dysfunction.

Moher Alsady T, Voskrebenzev A, Greer M, Becker L, Kaireit TF, Welte T, Wacker F, Gottlieb J, Vogel-Claussen J.

J Magn Reson Imaging. 2019 Dec;50(6):1873-1882. doi: 10.1002/jmri.26799. Epub 2019 May 27.


Valuing antibiotics: The role of the hospital clinician.

Masterton RG, Bassetti M, Chastre J, MacDonald AG, Rello J, Seaton RA, Welte T, Wilcox MH, West P.

Int J Antimicrob Agents. 2019 Jul;54(1):16-22. doi: 10.1016/j.ijantimicag.2019.05.012. Epub 2019 May 11.


The FMS-like tyrosine kinase-3 ligand/lung dendritic cell axis contributes to regulation of pulmonary fibrosis.

Tort Tarrés M, Aschenbrenner F, Maus R, Stolper J, Schuette L, Knudsen L, Lopez Rodriguez E, Jonigk D, Kühnel MP, DeLuca D, Prasse A, Welte T, Gauldie J, Kolb MR, Maus UA.

Thorax. 2019 Oct;74(10):947-957. doi: 10.1136/thoraxjnl-2018-212603. Epub 2019 May 10.


PMN-MDSCs Enhance CTC Metastatic Properties through Reciprocal Interactions via ROS/Notch/Nodal Signaling.

Sprouse ML, Welte T, Boral D, Liu HN, Yin W, Vishnoi M, Goswami-Sewell D, Li L, Pei G, Jia P, Glitza-Oliva IC, Marchetti D.

Int J Mol Sci. 2019 Apr 18;20(8). pii: E1916. doi: 10.3390/ijms20081916.


Azithromycin: The Holy Grail to Prevent Exacerbations in Chronic Respiratory Disease?

Welte T.

Am J Respir Crit Care Med. 2019 Aug 1;200(3):269-270. doi: 10.1164/rccm.201903-0706ED. No abstract available.


[Presumed consent for organ donation? : A survey among members of the German Society of Medical Intensive Care and Emergency Medicine].

Janssens U, Michels G, Karagiannidis C, Riessen R, Busch HJ, Welte T, Werdan K, Buerke M, John S, Kluge S.

Med Klin Intensivmed Notfmed. 2019 Apr 10. doi: 10.1007/s00063-019-0579-2. [Epub ahead of print] German.


Specific inhibition of splicing factor activity by decoy RNA oligonucleotides.

Denichenko P, Mogilevsky M, Cléry A, Welte T, Biran J, Shimshon O, Barnabas GD, Danan-Gotthold M, Kumar S, Yavin E, Levanon EY, Allain FH, Geiger T, Levkowitz G, Karni R.

Nat Commun. 2019 Apr 8;10(1):1590. doi: 10.1038/s41467-019-09523-0.


The clinical course of idiopathic pulmonary fibrosis and its association to quality of life over time: longitudinal data from the INSIGHTS-IPF registry.

Kreuter M, Swigris J, Pittrow D, Geier S, Klotsche J, Prasse A, Wirtz H, Koschel D, Andreas S, Claussen M, Grohé C, Wilkens H, Hagmeyer L, Skowasch D, Meyer JF, Kirschner J, Gläser S, Kahn N, Welte T, Neurohr C, Schwaiblmair M, Held M, Bahmer T, Oqueka T, Frankenberger M, Behr J.

Respir Res. 2019 Mar 15;20(1):59. doi: 10.1186/s12931-019-1020-3.


Ten tips for the intensive care management of transplanted lung patients.

Welte T, Ingels C, Rello J.

Intensive Care Med. 2019 Mar;45(3):371-373. doi: 10.1007/s00134-019-05578-1. Epub 2019 Mar 6. No abstract available.


Blood monocyte profiles in COPD patients with PiMM and PiZZ α1-antitrypsin.

Stolk J, Aggarwal N, Hochnadel I, Wrenger S, Martinez-Delgado B, Welte T, Yevsa T, Janciauskiene S.

Respir Med. 2019 Mar;148:60-62. doi: 10.1016/j.rmed.2019.02.001. Epub 2019 Feb 6.


Early improvement in severely ill patients with pneumonia treated with ceftobiprole: a retrospective analysis of two major trials.

Scheeren TWL, Welte T, Saulay M, Engelhardt M, Santerre-Henriksen A, Hamed K.

BMC Infect Dis. 2019 Feb 26;19(1):195. doi: 10.1186/s12879-019-3820-y.


Effect of COPD severity and comorbidities on the result of the PHQ-9 tool for the diagnosis of depression: results from the COSYCONET cohort study.

von Siemens SM, Jörres RA, Behr J, Alter P, Lutter J, Lucke T, Söhler S, Welte T, Watz H, Vogelmeier CF, Trudzinski F, Rief W, Herbig B, Kahnert K; COSYCONET study group.

Respir Res. 2019 Feb 11;20(1):30. doi: 10.1186/s12931-019-0997-y.


Procalcitonin (PCT)-guided antibiotic stewardship: an international experts consensus on optimized clinical use.

Schuetz P, Beishuizen A, Broyles M, Ferrer R, Gavazzi G, Gluck EH, González Del Castillo J, Jensen JU, Kanizsai PL, Kwa ALH, Krueger S, Luyt CE, Oppert M, Plebani M, Shlyapnikov SA, Toccafondi G, Townsend J, Welte T, Saeed K.

Clin Chem Lab Med. 2019 Aug 27;57(9):1308-1318. doi: 10.1515/cclm-2018-1181.


Transplantation of donor lungs with pulmonary embolism - a retrospective study.

Sommer W, Kirschner H, Ius F, Salman J, Siemeni T, Bobylev D, Avsar M, Kuehn C, Greer M, Gottlieb J, Rahmel A, Welte T, Haverich A, Tudorache I, Warnecke G.

Transpl Int. 2019 Jun;32(6):658-667. doi: 10.1111/tri.13407. Epub 2019 Feb 21.


Serum levels of hyaluronic acid are associated with COPD severity and predict survival.

Papakonstantinou E, Bonovolias I, Roth M, Tamm M, Schumann D, Baty F, Louis R, Milenkovic B, Boersma W, Stieltjes B, Kostikas K, Blasi F, Aerts JG, Rohde GGU, Lacoma A, Torres A, Welte T, Stolz D.

Eur Respir J. 2019 Mar 7;53(3). pii: 1801183. doi: 10.1183/13993003.01183-2018. Print 2019 Mar.


M. pneumoniae and C. pneumoniae are no relevant pathogens in critically ill patients with hospital-acquired respiratory tract infections.

Hagel S, Schmitt S, Kesselmeier M, Baier M, Welte T, Ewig S, Pletz MW.

Infection. 2019 Jun;47(3):471-474. doi: 10.1007/s15010-019-01273-x. Epub 2019 Jan 28.


Risk factors and outcomes of vocal cord paralysis after lung transplantation - a retrospective cohort study.

Seeliger B, Drick N, Avsar M, Tudorache I, Welte T, Gottlieb J, Greer M.

Transpl Int. 2019 Jun;32(6):626-634. doi: 10.1111/tri.13402. Epub 2019 Feb 8.


Effect of Indacaterol/Glycopyrronium on Pulmonary Perfusion and Ventilation in Hyperinflated Patients with Chronic Obstructive Pulmonary Disease (CLAIM). A Double-Blind, Randomized, Crossover Trial.

Vogel-Claussen J, Schönfeld CO, Kaireit TF, Voskrebenzev A, Czerner CP, Renne J, Tillmann HC, Berschneider K, Hiltl S, Bauersachs J, Welte T, Hohlfeld JM.

Am J Respir Crit Care Med. 2019 May 1;199(9):1086-1096. doi: 10.1164/rccm.201805-0995OC.


Low transmission risk of Pseudomonas aeruginosa in a bronchiectasis clinic based on the knowledge of bacterial population biology.

Cramer N, Sedlacek L, Tümmler B, Welte T.

Eur Respir J. 2019 Mar 28;53(3). pii: 1802191. doi: 10.1183/13993003.02191-2018. Print 2019 Mar. No abstract available.


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