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Invasive mould infections in solid organ transplant patients: modifiers and indicators of disease and treatment response.

Welte T, Len O, Muñoz P, Romani L, Lewis R, Perrella A.

Infection. 2019 Oct 1. doi: 10.1007/s15010-019-01360-z. [Epub ahead of print] Review.


Macrolide combination therapy for hospitalised CAP patients? An individualised approach supported by machine learning.

König R, Cao X, Oswald M, Forstner C, Rohde G, Rupp J, Witzenrath M, Welte T, Kolditz M, Pletz M; CAPNETZ study group.

Eur Respir J. 2019 Sep 19. pii: 1900824. doi: 10.1183/13993003.00824-2019. [Epub ahead of print]


The ERS fellowship portfolio: fostering excellence and diversity.

Morty RE, Donnelly LE, Stolz D, Roche N, Welte T, Forrest KA, Brightling CE, Brusselle GG.

Eur Respir J. 2019 Sep 5;54(3). pii: 1901503. doi: 10.1183/13993003.01503-2019. Print 2019 Sep. No abstract available.


Clinical Significance of SERPINA1 Gene and Its Encoded Alpha1-antitrypsin Protein in NSCLC.

Ercetin E, Richtmann S, Delgado BM, Gomez-Mariano G, Wrenger S, Korenbaum E, Liu B, DeLuca D, Kühnel MP, Jonigk D, Yuskaeva K, Warth A, Muley T, Winter H, Meister M, Welte T, Janciauskiene S, Schneider MA.

Cancers (Basel). 2019 Sep 4;11(9). pii: E1306. doi: 10.3390/cancers11091306.


Increasing bronchiectasis prevalence in Germany, 2009-2017: a population-based cohort study.

Ringshausen FC, Rademacher J, Pink I, de Roux A, Hickstein L, Ploner T, Welte T, Diel R.

Eur Respir J. 2019 Aug 29. pii: 1900499. doi: 10.1183/13993003.00499-2019. [Epub ahead of print] No abstract available.


Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms.

Kim IS, Gao Y, Welte T, Wang H, Liu J, Janghorban M, Sheng K, Niu Y, Goldstein A, Zhao N, Bado I, Lo HC, Toneff MJ, Nguyen T, Bu W, Jiang W, Arnold J, Gu F, He J, Jebakumar D, Walker K, Li Y, Mo Q, Westbrook TF, Zong C, Rao A, Sreekumar A, Rosen JM, Zhang XH.

Nat Cell Biol. 2019 Sep;21(9):1113-1126. doi: 10.1038/s41556-019-0373-7. Epub 2019 Aug 26.


Morphological and molecular motifs of fibrosing pulmonary injury patterns.

Jonigk D, Stark H, Braubach P, Neubert L, Shin HO, Izykowski N, Welte T, Janciauskiene S, Warnecke G, Haverich A, Kuehnel M, Laenger F.

J Pathol Clin Res. 2019 Aug 21. doi: 10.1002/cjp2.141. [Epub ahead of print]


Ceftaroline fosamil as a potential treatment option for Staphylococcus aureus community-acquired pneumonia in adults.

Welte T, Kantecki M, Stone GG, Hammond J.

Int J Antimicrob Agents. 2019 Oct;54(4):410-422. doi: 10.1016/j.ijantimicag.2019.08.012. Epub 2019 Aug 9. Review.


The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1.

Welte T, Tuck AC, Papasaikas P, Carl SH, Flemr M, Knuckles P, Rankova A, Bühler M, Großhans H.

Genes Dev. 2019 Sep 1;33(17-18):1221-1235. doi: 10.1101/gad.328492.119. Epub 2019 Aug 1.


Pleural Effusion in Adults-Etiology, Diagnosis, and Treatment.

Jany B, Welte T.

Dtsch Arztebl Int. 2019 May 24;116(21):377-386. doi: 10.3238/arztebl.2019.0377.


Consequences of chronic kidney disease in chronic obstructive pulmonary disease.

Trudzinski FC, Alqudrah M, Omlor A, Zewinger S, Fliser D, Speer T, Seiler F, Biertz F, Koch A, Vogelmeier C, Welte T, Watz H, Waschki B, Fähndrich S, Jörres R, Bals R; German COSYCONET consortium.

Respir Res. 2019 Jul 12;20(1):151. doi: 10.1186/s12931-019-1107-x.


SERPINA1 gene polymorphisms in a population-based ALSPAC cohort.

DeLuca DS, Poluzioroviene E, Taminskiene V, Wrenger S, Utkus A, Valiulis A, Alasevičius T, Henderson J, Bush A, Welte T, Janciauskiene S, Valiulis A.

Pediatr Pulmonol. 2019 Sep;54(9):1474-1478. doi: 10.1002/ppul.24422. Epub 2019 Jul 12.


Combined effects of lung function, blood gases and kidney function on the exacerbation risk in stable COPD: Results from the COSYCONET cohort.

Trudzinski FC, Kahnert K, Vogelmeier CF, Alter P, Seiler F, Fähndrich S, Watz H, Welte T, Speer T, Zewinger S, Biertz F, Kauczor HU, Jörres RA, Bals R; COSYCONET consortium.

Respir Med. 2019 Jul - Aug;154:18-26. doi: 10.1016/j.rmed.2019.06.007. Epub 2019 Jun 11.


PCR-based routine diagnostics uncover hidden burden of Legionnaires' disease.

Pletz MW, Ewig S, Welte T.

Lancet Infect Dis. 2019 Jul;19(7):681-683. doi: 10.1016/S1473-3099(19)30171-9. Epub 2019 Jun 10. No abstract available.


Left heart function in COPD : Impact of lung deflation.

Struß N, Bauersachs J, Welte T, Hohlfeld JM.

Herz. 2019 Sep;44(6):477-482. doi: 10.1007/s00059-019-4816-5.


Serum Levels of Alpha1-antitrypsin and Their Relationship With COPD in the General Spanish Population.

Janciauskiene S, DeLuca DS, Barrecheguren M, Welte T, Miravitlles M; Scientific Committee; Participating sites and coordinators.

Arch Bronconeumol. 2019 May 29. pii: S0300-2896(19)30112-7. doi: 10.1016/j.arbres.2019.03.001. [Epub ahead of print] English, Spanish.


Extracorporeal membrane oxygenation for acute respiratory distress syndrome due to Pneumocystis pneumonia.

Stahl K, Schenk H, Seeliger B, Wiesner O, Schmidt JJ, Bauersachs J, Welte T, Kühn C, Haverich A, Hoeper MM, David S.

Eur Respir J. 2019 Sep 19;54(3). pii: 1900410. doi: 10.1183/13993003.00410-2019. Print 2019 Sep. No abstract available.


MRI-derived regional flow-volume loop parameters detect early-stage chronic lung allograft dysfunction.

Moher Alsady T, Voskrebenzev A, Greer M, Becker L, Kaireit TF, Welte T, Wacker F, Gottlieb J, Vogel-Claussen J.

J Magn Reson Imaging. 2019 May 27. doi: 10.1002/jmri.26799. [Epub ahead of print]


Valuing antibiotics: The role of the hospital clinician.

Masterton RG, Bassetti M, Chastre J, MacDonald AG, Rello J, Seaton RA, Welte T, Wilcox MH, West P.

Int J Antimicrob Agents. 2019 Jul;54(1):16-22. doi: 10.1016/j.ijantimicag.2019.05.012. Epub 2019 May 11.


The FMS-like tyrosine kinase-3 ligand/lung dendritic cell axis contributes to regulation of pulmonary fibrosis.

Tort Tarrés M, Aschenbrenner F, Maus R, Stolper J, Schuette L, Knudsen L, Lopez Rodriguez E, Jonigk D, Kühnel MP, DeLuca D, Prasse A, Welte T, Gauldie J, Kolb MR, Maus UA.

Thorax. 2019 Oct;74(10):947-957. doi: 10.1136/thoraxjnl-2018-212603. Epub 2019 May 10.


PMN-MDSCs Enhance CTC Metastatic Properties through Reciprocal Interactions via ROS/Notch/Nodal Signaling.

Sprouse ML, Welte T, Boral D, Liu HN, Yin W, Vishnoi M, Goswami-Sewell D, Li L, Pei G, Jia P, Glitza-Oliva IC, Marchetti D.

Int J Mol Sci. 2019 Apr 18;20(8). pii: E1916. doi: 10.3390/ijms20081916.


Azithromycin: The Holy Grail to Prevent Exacerbations in Chronic Respiratory Disease?

Welte T.

Am J Respir Crit Care Med. 2019 Aug 1;200(3):269-270. doi: 10.1164/rccm.201903-0706ED. No abstract available.


[Presumed consent for organ donation? : A survey among members of the German Society of Medical Intensive Care and Emergency Medicine].

Janssens U, Michels G, Karagiannidis C, Riessen R, Busch HJ, Welte T, Werdan K, Buerke M, John S, Kluge S.

Med Klin Intensivmed Notfmed. 2019 Apr 10. doi: 10.1007/s00063-019-0579-2. [Epub ahead of print] German.


Specific inhibition of splicing factor activity by decoy RNA oligonucleotides.

Denichenko P, Mogilevsky M, Cléry A, Welte T, Biran J, Shimshon O, Barnabas GD, Danan-Gotthold M, Kumar S, Yavin E, Levanon EY, Allain FH, Geiger T, Levkowitz G, Karni R.

Nat Commun. 2019 Apr 8;10(1):1590. doi: 10.1038/s41467-019-09523-0.


The clinical course of idiopathic pulmonary fibrosis and its association to quality of life over time: longitudinal data from the INSIGHTS-IPF registry.

Kreuter M, Swigris J, Pittrow D, Geier S, Klotsche J, Prasse A, Wirtz H, Koschel D, Andreas S, Claussen M, Grohé C, Wilkens H, Hagmeyer L, Skowasch D, Meyer JF, Kirschner J, Gläser S, Kahn N, Welte T, Neurohr C, Schwaiblmair M, Held M, Bahmer T, Oqueka T, Frankenberger M, Behr J.

Respir Res. 2019 Mar 15;20(1):59. doi: 10.1186/s12931-019-1020-3.


Ten tips for the intensive care management of transplanted lung patients.

Welte T, Ingels C, Rello J.

Intensive Care Med. 2019 Mar;45(3):371-373. doi: 10.1007/s00134-019-05578-1. Epub 2019 Mar 6. No abstract available.


Blood monocyte profiles in COPD patients with PiMM and PiZZ α1-antitrypsin.

Stolk J, Aggarwal N, Hochnadel I, Wrenger S, Martinez-Delgado B, Welte T, Yevsa T, Janciauskiene S.

Respir Med. 2019 Mar;148:60-62. doi: 10.1016/j.rmed.2019.02.001. Epub 2019 Feb 6.


Early improvement in severely ill patients with pneumonia treated with ceftobiprole: a retrospective analysis of two major trials.

Scheeren TWL, Welte T, Saulay M, Engelhardt M, Santerre-Henriksen A, Hamed K.

BMC Infect Dis. 2019 Feb 26;19(1):195. doi: 10.1186/s12879-019-3820-y.


Effect of COPD severity and comorbidities on the result of the PHQ-9 tool for the diagnosis of depression: results from the COSYCONET cohort study.

von Siemens SM, Jörres RA, Behr J, Alter P, Lutter J, Lucke T, Söhler S, Welte T, Watz H, Vogelmeier CF, Trudzinski F, Rief W, Herbig B, Kahnert K; COSYCONET study group.

Respir Res. 2019 Feb 11;20(1):30. doi: 10.1186/s12931-019-0997-y.


Procalcitonin (PCT)-guided antibiotic stewardship: an international experts consensus on optimized clinical use.

Schuetz P, Beishuizen A, Broyles M, Ferrer R, Gavazzi G, Gluck EH, González Del Castillo J, Jensen JU, Kanizsai PL, Kwa ALH, Krueger S, Luyt CE, Oppert M, Plebani M, Shlyapnikov SA, Toccafondi G, Townsend J, Welte T, Saeed K.

Clin Chem Lab Med. 2019 Aug 27;57(9):1308-1318. doi: 10.1515/cclm-2018-1181.


Transplantation of donor lungs with pulmonary embolism - a retrospective study.

Sommer W, Kirschner H, Ius F, Salman J, Siemeni T, Bobylev D, Avsar M, Kuehn C, Greer M, Gottlieb J, Rahmel A, Welte T, Haverich A, Tudorache I, Warnecke G.

Transpl Int. 2019 Jun;32(6):658-667. doi: 10.1111/tri.13407. Epub 2019 Feb 21.


Serum levels of hyaluronic acid are associated with COPD severity and predict survival.

Papakonstantinou E, Bonovolias I, Roth M, Tamm M, Schumann D, Baty F, Louis R, Milenkovic B, Boersma W, Stieltjes B, Kostikas K, Blasi F, Aerts JG, Rohde GGU, Lacoma A, Torres A, Welte T, Stolz D.

Eur Respir J. 2019 Mar 7;53(3). pii: 1801183. doi: 10.1183/13993003.01183-2018. Print 2019 Mar.


M. pneumoniae and C. pneumoniae are no relevant pathogens in critically ill patients with hospital-acquired respiratory tract infections.

Hagel S, Schmitt S, Kesselmeier M, Baier M, Welte T, Ewig S, Pletz MW.

Infection. 2019 Jun;47(3):471-474. doi: 10.1007/s15010-019-01273-x. Epub 2019 Jan 28.


Risk factors and outcomes of vocal cord paralysis after lung transplantation - a retrospective cohort study.

Seeliger B, Drick N, Avsar M, Tudorache I, Welte T, Gottlieb J, Greer M.

Transpl Int. 2019 Jun;32(6):626-634. doi: 10.1111/tri.13402. Epub 2019 Feb 8.


Effect of Indacaterol/Glycopyrronium on Pulmonary Perfusion and Ventilation in Hyperinflated Patients with Chronic Obstructive Pulmonary Disease (CLAIM). A Double-Blind, Randomized, Crossover Trial.

Vogel-Claussen J, Schönfeld CO, Kaireit TF, Voskrebenzev A, Czerner CP, Renne J, Tillmann HC, Berschneider K, Hiltl S, Bauersachs J, Welte T, Hohlfeld JM.

Am J Respir Crit Care Med. 2019 May 1;199(9):1086-1096. doi: 10.1164/rccm.201805-0995OC.


Low transmission risk of Pseudomonas aeruginosa in a bronchiectasis clinic based on the knowledge of bacterial population biology.

Cramer N, Sedlacek L, Tümmler B, Welte T.

Eur Respir J. 2019 Mar 28;53(3). pii: 1802191. doi: 10.1183/13993003.02191-2018. Print 2019 Mar. No abstract available.


Single- and multiple-dose pharmacokinetics and total removal of colistin in critically ill patients with acute kidney injury undergoing prolonged intermittent renal replacement therapy.

Schmidt JJ, Strunk AK, David S, Bode-Böger SM, Martens-Lobenhoffer J, Knitsch W, Scherneck S, Welte T, Kielstein JT.

J Antimicrob Chemother. 2019 Apr 1;74(4):997-1002. doi: 10.1093/jac/dky511.


The European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) ERS Clinical Research Collaboration.

Aliberti S, Polverino E, Chalmers JD, Altenburg J, Shteinberg M, Goeminne PC, Welte T, Shoemark A, Almagro M, Blasi F; EMBARC Clinical Research Collaboration.

Eur Respir J. 2018 Nov 29;52(5). pii: 1802074. doi: 10.1183/13993003.02074-2018. Print 2018 Nov. No abstract available.


The European Respiratory Society's 10 Principles for Lung Health.

Horváth I, Barry M, Brusselle G, Burghuber OC, Bush A, Robalo Cordeiro C, Gaga M, Gratziou C, Saraiva I, Stolz D, Troosters T, Welte T, Migliori GB, Joos G.

Eur Respir J. 2018 Nov 29;52(5). pii: 1801373. doi: 10.1183/13993003.01373-2018. Print 2018 Nov. No abstract available.


Clinical course, treatment and outcome of Pneumocystis pneumonia in immunocompromised adults: a retrospective analysis over 17 years.

Schmidt JJ, Lueck C, Ziesing S, Stoll M, Haller H, Gottlieb J, Eder M, Welte T, Hoeper MM, Scherag A, David S.

Crit Care. 2018 Nov 19;22(1):307. doi: 10.1186/s13054-018-2221-8.


Structural and Kinetic Profiling of Allosteric Modulation of Duplex DNA Induced by DNA-Binding Polyamide Analogues.

Aman K, Padroni G, Parkinson JA, Welte T, Burley GA.

Chemistry. 2019 Feb 21;25(11):2757-2763. doi: 10.1002/chem.201805338. Epub 2019 Jan 14.


Early therapeutic plasma exchange in septic shock: a prospective open-label nonrandomized pilot study focusing on safety, hemodynamics, vascular barrier function, and biologic markers.

Knaup H, Stahl K, Schmidt BMW, Idowu TO, Busch M, Wiesner O, Welte T, Haller H, Kielstein JT, Hoeper MM, David S.

Crit Care. 2018 Oct 30;22(1):285. doi: 10.1186/s13054-018-2220-9.


Comparison of quantitative regional perfusion-weighted phase resolved functional lung (PREFUL) MRI with dynamic gadolinium-enhanced regional pulmonary perfusion MRI in COPD patients.

Kaireit TF, Voskrebenzev A, Gutberlet M, Freise J, Jobst B, Kauczor HU, Welte T, Wacker F, Vogel-Claussen J.

J Magn Reson Imaging. 2019 Apr;49(4):1122-1132. doi: 10.1002/jmri.26342. Epub 2018 Oct 22.


ERS Clinical Research Collaborations: underpinning research excellence.

Brightling C, Genton C, Bill W, Welte T, Gaga M, Heuvelin E, Brusselle G.

Eur Respir J. 2018 Sep 15;52(3). pii: 1801534. doi: 10.1183/13993003.01534-2018. Print 2018 Sep. No abstract available.


The European Respiratory Society: ensuring excellence through education best practice.

Farr A, Gaga M, Welte T, Troosters T, Joos G, Robalo Cordeiro C, Burghuber OC, Brusselle G, Gratziou CG, Bush A, Saraiva I, Pannetier C, Stolz D.

Eur Respir J. 2018 Sep 15;52(3). pii: 1801248. doi: 10.1183/13993003.01248-2018. Print 2018 Sep. No abstract available.


[The 2017/2018 influenza season-business as usual? : A statement of medical societies].

Kochanek M, Böll B, Shimabukuro-Vornhagen A, Welte T, Wieland U, Pletz M, Hallek M, Fätkenheuer G, Salzberger B.

Internist (Berl). 2018 Oct;59(10):1122-1124. doi: 10.1007/s00108-018-0501-7. German. No abstract available.


[Pneumological Assessment with Regard to Performance Demands - Concept: "Load to Capacity"].

Kroidl RF, Fröhlich MJ, Welte T.

Pneumologie. 2018 Nov;72(11):e2. doi: 10.1055/a-0721-0598. Epub 2018 Aug 30. German. No abstract available.


Why, when and how to investigate primary ciliary dyskinesia in adult patients with bronchiectasis.

Contarini M, Shoemark A, Rademacher J, Finch S, Gramegna A, Gaffuri M, Roncoroni L, Seia M, Ringshausen FC, Welte T, Blasi F, Aliberti S, Chalmers JD.

Multidiscip Respir Med. 2018 Aug 9;13(Suppl 1):26. doi: 10.1186/s40248-018-0143-6. eCollection 2018. Review.


Lobe-wise assessment of lung volume and density distribution in lung transplant patients and value for early detection of bronchiolitis obliterans syndrome.

Dettmer S, Suhling H, Klingenberg I, Otten O, Kaireit T, Fuge J, Kuhnigk JM, Gottlieb J, Haverich A, Welte T, Wacker F, Vogel-Claussen J, Shin HO.

Eur J Radiol. 2018 Sep;106:137-144. doi: 10.1016/j.ejrad.2018.07.016. Epub 2018 Jul 25.


[The lung in systemic diseases : Between holistic and individualized medicine-a challenge for internal medicine].

Welte T, Vogelmeier C, Hiddemann W, Märker-Hermann E.

Internist (Berl). 2018 Sep;59(9):873-875. doi: 10.1007/s00108-018-0481-7. German. No abstract available.


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