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Items: 1 to 50 of 79


Cartilage Quality (dGEMRIC Index) Following Knee Joint Distraction or High Tibial Osteotomy.

Besselink NJ, Vincken KL, Bartels LW, van Heerwaarden RJ, Concepcion AN, Marijnissen ACA, Spruijt S, Custers RJH, van der Woude JAD, Wiegant K, Welsing PMJ, Mastbergen SC, Lafeber FPJG.

Cartilage. 2018 Jun 1:1947603518777578. doi: 10.1177/1947603518777578. [Epub ahead of print]


Inadequate response to treat-to-target methotrexate therapy in patients with new-onset rheumatoid arthritis: development and validation of clinical predictors.

Teitsma XM, Jacobs JWG, Welsing PMJ, de Jong PHP, Hazes JMW, Weel AEAM, Pethö-Schramm A, Borm MEA, van Laar JM, Lafeber FPJG, Bijlsma JWJ.

Ann Rheum Dis. 2018 May 14. pii: annrheumdis-2018-213035. doi: 10.1136/annrheumdis-2018-213035. [Epub ahead of print]


Local and systemic inflammatory lipid profiling in a rat model of osteoarthritis with metabolic dysregulation.

de Visser HM, Mastbergen SC, Ravipati S, Welsing PMJ, Pinto FC, Lafeber FPJG, Chapman V, Barrett DA, Weinans H.

PLoS One. 2018 Apr 23;13(4):e0196308. doi: 10.1371/journal.pone.0196308. eCollection 2018.


The impact of oral food challenges for food allergy on quality of life: A systematic review.

Kansen HM, Le TM, Meijer Y, Flokstra-de Blok BMJ, Welsing PMJ, van der Ent CK, Knulst AC, van Erp FC.

Pediatr Allergy Immunol. 2018 Apr 16. doi: 10.1111/pai.12905. [Epub ahead of print]


The impact of patient global assessment in the definition of remission as a predictor of long-term radiographic damage in patients with rheumatoid arthritis: protocol for an individual patient data meta-analysis.

Ferreira RJO, Welsing PMJ, Gossec L, Jacobs JWG, Machado PM, Ndosi M, van der Heijde D, da Silva JAP.

Acta Reumatol Port. 2018 Jan-Mar;43(1):52-60.


Disease burden of knee osteoarthritis patients with a joint replacement compared to matched controls: a population-based analysis of a Dutch medical claims database.

Nielen JTH, Boonen A, Dagnelie PC, van den Bemt BJF, Emans PJ, Lafeber FPJG, van Spil WE, de Vries F, Welsing PMJ.

Osteoarthritis Cartilage. 2018 Feb;26(2):202-210. doi: 10.1016/j.joca.2017.11.012. Epub 2017 Dec 2.


Radiographic joint damage in early rheumatoid arthritis patients: comparing tocilizumab- and methotrexate-based treat-to-target strategies.

Teitsma XM, Jacobs JWG, Welsing PMJ, Pethö-Schramm A, Borm MEA, van Laar JM, Lafeber FPJG, Bijlsma JWJ.

Rheumatology (Oxford). 2018 Feb 1;57(2):309-317. doi: 10.1093/rheumatology/kex386.


Patient-reported outcomes in newly diagnosed early rheumatoid arthritis patients treated to target with a tocilizumab- or methotrexate-based strategy.

Teitsma XM, Jacobs JWG, Welsing PMJ, Pethö-Schramm A, Borm MEA, Hendriks L, Denissen NHAM, van Laar JM, Lafeber FPJG, Bijlsma JWJ.

Rheumatology (Oxford). 2017 Dec 1;56(12):2179-2189. doi: 10.1093/rheumatology/kex319.


A sex-specific association between incident radiographic osteoarthritis of hip or knee and incident peripheral arterial calcifications: 8-year prospective data from Cohort Hip and Cohort Knee (CHECK).

Gielis WP, Welsing PMJ, van Spil WE, Runhaar J, Weinans H, de Jong PA.

Osteoarthritis Cartilage. 2017 Nov;25(11):1814-1821. doi: 10.1016/j.joca.2017.07.016. Epub 2017 Jul 28.


Series: Pragmatic trials and real world evidence: Paper 5. Usual care and real life comparators.

Zuidgeest MGP, Welsing PMJ, van Thiel GJMW, Ciaglia A, Alfonso-Cristancho R, Eckert L, Eijkemans MJC, Egger M; WP3 of the GetReal consortium.

J Clin Epidemiol. 2017 Oct;90:92-98. doi: 10.1016/j.jclinepi.2017.07.001. Epub 2017 Jul 8.


A disconnect between disease activity and functional ability already in patients with early rheumatoid arthritis, depending on large joint involvement.

Rubbert-Roth A, Jacobs JWG, Bijlsma JWJ, Welsing PMJ.

Ann Rheum Dis. 2018 Jul;77(7):1085-1086. doi: 10.1136/annrheumdis-2017-211485. Epub 2017 Jun 23. No abstract available.


Series: Pragmatic trials and real world evidence: Paper 6. Outcome measures in the real world.

Welsing PM, Oude Rengerink K, Collier S, Eckert L, van Smeden M, Ciaglia A, Nachbaur G, Trelle S, Taylor AJ, Egger M, Goetz I; Work Package 3 of the GetReal Consortium.

J Clin Epidemiol. 2017 Oct;90:99-107. doi: 10.1016/j.jclinepi.2016.12.022. Epub 2017 May 11.


Differences between serum polar lipid profiles of male and female rheumatoid arthritis patients in response to glucocorticoid treatment.

Fu J, Cuppen BV, Welsing PM, van Wietmarschen H, Harms AC, Berger R, Koval S, Fritsch-Stork RD, Bijlsma JW, Hankemeier T, van der Greef J, Lafeber FP.

Inflammopharmacology. 2016 Dec;24(6):397-402. Epub 2016 Sep 28.


Prediction of cartilaginous tissue repair after knee joint distraction.

van der Woude JA, Welsing PM, van Roermund PM, Custers RJ, Kuchuk NO, Lafeber FP.

Knee. 2016 Oct;23(5):792-5. doi: 10.1016/j.knee.2016.02.015. Epub 2016 Aug 17.


Early rheumatoid arthritis treated with tocilizumab, methotrexate, or their combination (U-Act-Early): a multicentre, randomised, double-blind, double-dummy, strategy trial.

Bijlsma JWJ, Welsing PMJ, Woodworth TG, Middelink LM, Pethö-Schramm A, Bernasconi C, Borm MEA, Wortel CH, Ter Borg EJ, Jahangier ZN, van der Laan WH, Bruyn GAW, Baudoin P, Wijngaarden S, Vos PAJM, Bos R, Starmans MJF, Griep EN, Griep-Wentink JRM, Allaart CF, Heurkens AHM, Teitsma XM, Tekstra J, Marijnissen ACA, Lafeber FPJ, Jacobs JWG.

Lancet. 2016 Jul 23;388(10042):343-355. doi: 10.1016/S0140-6736(16)30363-4. Epub 2016 Jun 7.


Knee Joint Distraction Compared to Total Knee Arthroplasty for Treatment of End Stage Osteoarthritis: Simulating Long-Term Outcomes and Cost-Effectiveness.

van der Woude JA, Nair SC, Custers RJ, van Laar JM, Kuchuck NO, Lafeber FP, Welsing PM.

PLoS One. 2016 May 12;11(5):e0155524. doi: 10.1371/journal.pone.0155524. eCollection 2016.


A Personalized Approach to Biological Therapy Using Prediction of Clinical Response Based on MRP8/14 Serum Complex Levels in Rheumatoid Arthritis Patients.

Nair SC, Welsing PM, Choi IY, Roth J, Holzinger D, Bijlsma JW, van Laar JM, Gerlag DM, Lafeber FP, Tak PP.

PLoS One. 2016 Mar 30;11(3):e0152362. doi: 10.1371/journal.pone.0152362. eCollection 2016.


Determining the Lowest Optimally Effective Methotrexate Dose for Individual RA Patients Using Their Dose Response Relation in a Tight Control Treatment Approach.

Nair SC, Jacobs JW, Bakker MF, Jahangier ZN, Bijlsma JW, van Laar JM, Lafeber FP, Welsing PM; Utrecht Arthritis Cohort Study Group.

PLoS One. 2016 Mar 17;11(3):e0148791. doi: 10.1371/journal.pone.0148791. eCollection 2016.


Predicting the 10-year risk of hip and major osteoporotic fracture in rheumatoid arthritis and in the general population: an independent validation and update of UK FRAX without bone mineral density.

Klop C, de Vries F, Bijlsma JW, Leufkens HG, Welsing PM.

Ann Rheum Dis. 2016 Dec;75(12):2095-2100. doi: 10.1136/annrheumdis-2015-208958. Epub 2016 Mar 16.


Personalized biological treatment for rheumatoid arthritis: a systematic review with a focus on clinical applicability.

Cuppen BV, Welsing PM, Sprengers JJ, Bijlsma JW, Marijnissen AC, van Laar JM, Lafeber FP, Nair SC.

Rheumatology (Oxford). 2016 May;55(5):826-39. doi: 10.1093/rheumatology/kev421. Epub 2015 Dec 29. Review.


The Epidemiology of Hip and Major Osteoporotic Fractures in a Dutch Population of Community-Dwelling Elderly: Implications for the Dutch FRAX® Algorithm.

Klop C, Welsing PM, Leufkens HG, Elders PJ, Overbeek JA, van den Bergh JP, Bijlsma JW, de Vries F.

PLoS One. 2015 Dec 3;10(12):e0143800. doi: 10.1371/journal.pone.0143800. eCollection 2015.


Economic evaluation of a tight-control treatment strategy using an imaging device (handscan) for monitoring joint inflammation in early rheumatoid arthritis.

Nair SC, Welsing PM, Jacobs JW, van Laar JM, Rensen WH, Ardine de Wit G, Bijlsma JW, Lafeber FP.

Clin Exp Rheumatol. 2015 Nov-Dec;33(6):831-8. Epub 2015 Sep 7.


Does disease activity add to functional disability in estimation of utility for rheumatoid arthritis patients on biologic treatment?

Nair SC, Welsing PM, Marijnissen AK, Sijtsma P, Bijlsma JW, van Laar JM, Lafeber FP, de Wit GA.

Rheumatology (Oxford). 2016 Jan;55(1):94-102. doi: 10.1093/rheumatology/kev291. Epub 2015 Aug 27.


Statistical modelling: essentially, all models are wrong, but some are useful. Review series on statistical modelling.

Welsing PM.

Rheumatology (Oxford). 2015 Jul;54(7):1133-4. doi: 10.1093/rheumatology/kev116. Epub 2015 May 13. No abstract available.


Anti-osteoporosis drug prescribing after hip fracture in the UK: 2000-2010.

Klop C, Gibson-Smith D, Elders PJ, Welsing PM, Leufkens HG, Harvey NC, Bijlsma JW, van Staa TP, de Vries F.

Osteoporos Int. 2015 Jul;26(7):1919-28. doi: 10.1007/s00198-015-3098-x. Epub 2015 May 12.


Long-term persistence with anti-osteoporosis drugs after fracture.

Klop C, Welsing PM, Elders PJ, Overbeek JA, Souverein PC, Burden AM, van Onzenoort HA, Leufkens HG, Bijlsma JW, de Vries F.

Osteoporos Int. 2015 Jun;26(6):1831-40. doi: 10.1007/s00198-015-3084-3. Epub 2015 Mar 31.


The ability of systemic biochemical markers to reflect presence, incidence, and progression of early-stage radiographic knee and hip osteoarthritis: data from CHECK.

Van Spil WE, Welsing PM, Bierma-Zeinstra SM, Bijlsma JW, Roorda LD, Cats HA, Lafeber FP.

Osteoarthritis Cartilage. 2015 Aug;23(8):1388-97. doi: 10.1016/j.joca.2015.03.023. Epub 2015 Mar 26.


Contribution of the subjective components of the disease activity score to the response to biologic treatment in rheumatoid arthritis.

Jurgens MS, Overman CL, Jacobs JW, Geenen R, Cuppen BV, Marijnissen AC, Bijlsma JW, Welsing PM, Lafeber FP, van Laar JM; Utrecht Arthritis Cohort Study Group.

Arthritis Care Res (Hoboken). 2015 Jul;67(7):923-8. doi: 10.1002/acr.22532.


Systemic biochemical markers of joint metabolism and inflammation in relation to radiographic parameters and pain of the knee: data from CHECK, a cohort of early-osteoarthritis subjects.

Van Spil WE, Nair SC, Kinds MB, Emans PJ, Hilberdink WK, Welsing PM, Lafeber FP.

Osteoarthritis Cartilage. 2015 Jan;23(1):48-56. doi: 10.1016/j.joca.2014.09.003. Epub 2014 Sep 6.


The risk of major and any (non-hip) fragility fracture after hip fracture in the United Kingdom: 2000-2010.

Gibson-Smith D, Klop C, Elders PJ, Welsing PM, van Schoor N, Leufkens HG, Harvey NC, van Staa TP, de Vries F.

Osteoporos Int. 2014 Nov;25(11):2555-63. doi: 10.1007/s00198-014-2799-x. Epub 2014 Jul 8.


Mortality in British hip fracture patients, 2000-2010: a population-based retrospective cohort study.

Klop C, Welsing PM, Cooper C, Harvey NC, Elders PJ, Bijlsma JW, Leufkens HG, de Vries F.

Bone. 2014 Sep;66:171-7. doi: 10.1016/j.bone.2014.06.011. Epub 2014 Jun 14.


The separate impact of tight control schemes and disease activity on quality of life in patients with early rheumatoid arthritis: results from the CAMERA trials.

Jurgens MS, Welsing PM, Geenen R, Bakker MF, Schenk Y, de Man YA, Bijlsma JW, Lafeber FP, Jacobs JW.

Clin Exp Rheumatol. 2014 May-Jun;32(3):369-76. Epub 2014 Feb 25.


Generalization and extrapolation of treatment effects from clinical studies in rheumatoid arthritis.

Nair SC, Kievit W, Janse RW, Bijlsma JW, Fransen J, Lafeber FP, Welsing PM.

Arthritis Care Res (Hoboken). 2014 Jul;66(7):998-1007. doi: 10.1002/acr.22269.


Personalised treatment using serum drug levels of adalimumab in patients with rheumatoid arthritis: an evaluation of costs and effects.

Krieckaert CL, Nair SC, Nurmohamed MT, van Dongen CJ, Lems WF, Lafeber FP, Bijlsma JW, Koffijberg H, Wolbink G, Welsing PM.

Ann Rheum Dis. 2015 Feb;74(2):361-8. doi: 10.1136/annrheumdis-2013-204101. Epub 2013 Nov 21.


Patient characteristics as predictors of clinical outcome of distraction in treatment of severe ankle osteoarthritis.

Marijnissen AC, Hoekstra MC, Pré BC, van Roermund PM, van Melkebeek J, Amendola A, Maathuis P, Lafeber FP, Welsing PM.

J Orthop Res. 2014 Jan;32(1):96-101. doi: 10.1002/jor.22475. Epub 2013 Aug 27.


Do radiographic joint damage and disease activity influence functional disability through different mechanisms? Direct and indirect effects of disease activity in established rheumatoid arthritis.

Nair SC, Bijlsma JW, van der Werf JH, van der Veen MJ, Linn-Rasker SP, Vreugdenhil S, Lafeber FP, Welsing PM.

J Rheumatol. 2013 Sep;40(9):1505-12. doi: 10.3899/jrheum.121346. Epub 2013 Jul 1.


Identifying phenotypes of knee osteoarthritis by separate quantitative radiographic features may improve patient selection for more targeted treatment.

Kinds MB, Marijnissen AC, Viergever MA, Emans PJ, Lafeber FP, Welsing PM.

J Rheumatol. 2013 Jun;40(6):891-902. doi: 10.3899/jrheum.121004. Epub 2013 May 1.


Skin pentosidine in very early hip/knee osteoarthritis (CHECK) is not a strong independent predictor of radiographic progression over 5 years follow-up.

Vos PA, Welsing PM, deGroot J, Huisman AM, Oostveen JC, Reijman M, Damen J, Mastbergen SC, Lafeber FP.

Osteoarthritis Cartilage. 2013 Jun;21(6):823-30. doi: 10.1016/j.joca.2013.03.006. Epub 2013 Mar 27.


Quantitative radiographic features of early knee osteoarthritis: development over 5 years and relationship with symptoms in the CHECK cohort.

Kinds MB, Marijnissen AC, Bijlsma JW, Boers M, Lafeber FP, Welsing PM.

J Rheumatol. 2013 Jan;40(1):58-65. doi: 10.3899/jrheum.120320. Epub 2012 Nov 1.


Impact of self-reported comorbidity on physical and mental health status in early symptomatic osteoarthritis: the CHECK (Cohort Hip and Cohort Knee) study.

Wesseling J, Welsing PM, Bierma-Zeinstra SM, Dekker J, Gorter KJ, Kloppenburg M, Roorda LD, Bijlsma JW.

Rheumatology (Oxford). 2013 Jan;52(1):180-8. doi: 10.1093/rheumatology/kes288. Epub 2012 Oct 23.


Overview and analysis of treat-to-target trials in rheumatoid arthritis reporting on remission.

Jurgens MS, Welsing PM, Jacobs JW.

Clin Exp Rheumatol. 2012 Jul-Aug;30(4 Suppl 73):S56-63. Epub 2012 Oct 16. Review.


COX-2-selective NSAIDs and risk of hip or knee replacements: a population-based case-control study.

Klop C, de Vries F, Lalmohamed A, Mastbergen SC, Leufkens HG, Noort-van der Laan WH, Bijlsma JW, Welsing PM.

Calcif Tissue Int. 2012 Dec;91(6):387-94. doi: 10.1007/s00223-012-9646-x. Epub 2012 Oct 9.


Are changes in bone mineral density different between groups of early rheumatoid arthritis patients treated according to a tight control strategy with or without prednisone if osteoporosis prophylaxis is applied?

van der Goes MC, Jacobs JW, Jurgens MS, Bakker MF, van der Veen MJ, van der Werf JH, Welsing PM, Bijlsma JW.

Osteoporos Int. 2013 Apr;24(4):1429-36. doi: 10.1007/s00198-012-2073-z. Epub 2012 Aug 2.


Cross-sectional and predictive associations between plasma adipokines and radiographic signs of early-stage knee osteoarthritis: data from CHECK.

Van Spil WE, Welsing PM, Kloppenburg M, Bierma-Zeinstra SM, Bijlsma JW, Mastbergen SC, Lafeber FP.

Osteoarthritis Cartilage. 2012 Nov;20(11):1278-85. doi: 10.1016/j.joca.2012.08.001. Epub 2012 Aug 10.


Increase of body mass index in a tight controlled methotrexate-based strategy with prednisone in early rheumatoid arthritis: side effect of the prednisone or better control of disease activity?

Jurgens MS, Jacobs JW, Geenen R, Bossema ER, Bakker MF, Bijlsma JW, van Albada-Kuipers IA, Ehrlich JC, Lafeber FP, Welsing PM; Utrecht Arthritis Cohort Study Group.

Arthritis Care Res (Hoboken). 2013 Jan;65(1):88-93. doi: 10.1002/acr.21797.


Performance of a multi-biomarker score measuring rheumatoid arthritis disease activity in the CAMERA tight control study.

Bakker MF, Cavet G, Jacobs JW, Bijlsma JW, Haney DJ, Shen Y, Hesterberg LK, Smith DR, Centola M, van Roon JA, Lafeber FP, Welsing PM.

Ann Rheum Dis. 2012 Oct;71(10):1692-7. doi: 10.1136/annrheumdis-2011-200963. Epub 2012 May 17.


Influence of variation in semiflexed knee positioning during image acquisition on separate quantitative radiographic parameters of osteoarthritis, measured by Knee Images Digital Analysis.

Kinds MB, Vincken KL, Hoppinga TN, Bleys RL, Viergever MA, Marijnissen AC, Welsing PM, Lafeber FP.

Osteoarthritis Cartilage. 2012 Sep;20(9):997-1003. doi: 10.1016/j.joca.2012.04.016. Epub 2012 Apr 26.


Clusters within a wide spectrum of biochemical markers for osteoarthritis: data from CHECK, a large cohort of individuals with very early symptomatic osteoarthritis.

van Spil WE, Jansen NW, Bijlsma JW, Reijman M, DeGroot J, Welsing PM, Lafeber FP.

Osteoarthritis Cartilage. 2012 Jul;20(7):745-54. doi: 10.1016/j.joca.2012.04.004. Epub 2012 Apr 11.


Risk factors for perinatal arterial ischaemic stroke in full-term infants: a case-control study.

Harteman JC, Groenendaal F, Kwee A, Welsing PM, Benders MJ, de Vries LS.

Arch Dis Child Fetal Neonatal Ed. 2012 Nov;97(6):F411-6. doi: 10.1136/archdischild-2011-300973. Epub 2012 Mar 24.


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