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Items: 1 to 50 of 83

1.

Membrane Lipid-KIR2.x Channel Interactions Enable Hemodynamic Sensing in Cerebral Arteries.

Sancho M, Fabris S, Hald BO, Brett SE, Sandow SL, Poepping TL, Welsh DG.

Arterioscler Thromb Vasc Biol. 2019 Jun;39(6):1072-1087. doi: 10.1161/ATVBAHA.119.312493.

PMID:
31043073
2.

An assessment of KIR channel function in human cerebral arteries.

Sancho M, Gao Y, Hald BO, Yin H, Boulton M, Steven DA, MacDougall KW, Parrent AG, Pickering JG, Welsh DG.

Am J Physiol Heart Circ Physiol. 2019 Apr 1;316(4):H794-H800. doi: 10.1152/ajpheart.00022.2019. Epub 2019 Jan 25.

PMID:
30681365
3.

Electrical amplification: KIR channels taking centre stage in the hyperaemic debate.

Welsh DG.

J Physiol. 2019 Mar;597(5):1223-1224. doi: 10.1113/JP277513. Epub 2019 Jan 28. No abstract available.

PMID:
30615195
4.

Caveolae Link CaV3.2 Channels to BKCa-Mediated Feedback in Vascular Smooth Muscle.

Hashad AM, Harraz OF, Brett SE, Romero M, Kassmann M, Puglisi JL, Wilson SM, Gollasch M, Welsh DG.

Arterioscler Thromb Vasc Biol. 2018 Oct;38(10):2371-2381. doi: 10.1161/ATVBAHA.118.311394.

PMID:
30354206
5.

Differential targeting and signalling of voltage-gated T-type Cav 3.2 and L-type Cav 1.2 channels to ryanodine receptors in mesenteric arteries.

Fan G, Kaßmann M, Hashad AM, Welsh DG, Gollasch M.

J Physiol. 2018 Oct;596(20):4863-4877. doi: 10.1113/JP276923. Epub 2018 Sep 15.

6.

Reactive Oxygen Species Mediate the Suppression of Arterial Smooth Muscle T-type Ca2+ Channels by Angiotensin II.

Hashad AM, Sancho M, Brett SE, Welsh DG.

Sci Rep. 2018 Feb 22;8(1):3445. doi: 10.1038/s41598-018-21899-5.

7.

Perivascular adipose tissue and the dynamic regulation of Kv 7 and Kir channels: Implications for resistant hypertension.

Gollasch M, Welsh DG, Schubert R.

Microcirculation. 2018 Jan;25(1). doi: 10.1111/micc.12434. Review.

PMID:
29211322
8.

The Conducted Vasomotor Response: Function, Biophysical Basis, and Pharmacological Control.

Welsh DG, Tran CHT, Hald BO, Sancho M.

Annu Rev Pharmacol Toxicol. 2018 Jan 6;58:391-410. doi: 10.1146/annurev-pharmtox-010617-052623. Epub 2017 Oct 2. Review.

PMID:
28968190
9.

Endothelial signaling and the dynamic regulation of arterial tone: A surreptitious relationship.

Welsh DG, Longden TA.

Microcirculation. 2017 Apr;24(3). doi: 10.1111/micc.12370.

PMID:
28303623
10.

Altered distribution of adrenergic constrictor responses contributes to skeletal muscle perfusion abnormalities in metabolic syndrome.

Lemaster K, Jackson D, Welsh DG, Brooks SD, Chantler PD, Frisbee JC.

Microcirculation. 2017 Feb;24(2). doi: 10.1111/micc.12349.

11.

Structural analysis of endothelial projections from mesenteric arteries.

Maarouf N, Sancho M, Fürstenhaupt T, Tran CH, Welsh DG.

Microcirculation. 2017 Apr;24(3). doi: 10.1111/micc.12330.

PMID:
27809400
12.

Interplay among distinct Ca2+ conductances drives Ca2+ sparks/spontaneous transient outward currents in rat cerebral arteries.

Hashad AM, Mazumdar N, Romero M, Nygren A, Bigdely-Shamloo K, Harraz OF, Puglisi JL, Vigmond EJ, Wilson SM, Welsh DG.

J Physiol. 2017 Feb 15;595(4):1111-1126. doi: 10.1113/JP273329. Epub 2016 Dec 12.

13.

KIR channels tune electrical communication in cerebral arteries.

Sancho M, Samson NC, Hald BO, Hashad AM, Marrelli SP, Brett SE, Welsh DG.

J Cereb Blood Flow Metab. 2017 Jun;37(6):2171-2184. doi: 10.1177/0271678X16662041. Epub 2016 Jan 1.

14.

The Secret Life of Telomerase.

Welsh DG.

Circ Res. 2016 Mar 4;118(5):781-2. doi: 10.1161/CIRCRESAHA.116.308290. No abstract available.

PMID:
26941421
15.

Abnormal Lymphatic Channels Detected by T2-Weighted MR Imaging as a Substrate for Ventricular Arrhythmia in HCM.

Kolman L, Welsh DG, Vigmond E, Joncas SX, Stirrat J, Scholl D, Rajchl M, Tweedie E, Mikami Y, Lydell C, Howarth A, Yee R, White JA.

JACC Cardiovasc Imaging. 2016 Nov;9(11):1354-1356. doi: 10.1016/j.jcmg.2015.10.016. Epub 2016 Jan 6. No abstract available.

16.

Implications of αvβ3 Integrin Signaling in the Regulation of Ca2+ Waves and Myogenic Tone in Cerebral Arteries.

Mufti RE, Zechariah A, Sancho M, Mazumdar N, Brett SE, Welsh DG.

Arterioscler Thromb Vasc Biol. 2015 Dec;35(12):2571-8. doi: 10.1161/ATVBAHA.115.305619. Epub 2015 Oct 22.

PMID:
26494230
17.

Activation of endothelial IKCa channels underlies NO-dependent myoendothelial feedback.

Kerr PM, Wei R, Tam R, Sandow SL, Murphy TV, Ondrusova K, Lunn SE, Tran CHT, Welsh DG, Plane F.

Vascul Pharmacol. 2015 Nov;74:130-138. doi: 10.1016/j.vph.2015.09.001. Epub 2015 Sep 9.

PMID:
26362477
18.

Genetic ablation of CaV3.2 channels enhances the arterial myogenic response by modulating the RyR-BKCa axis.

Harraz OF, Brett SE, Zechariah A, Romero M, Puglisi JL, Wilson SM, Welsh DG.

Arterioscler Thromb Vasc Biol. 2015 Aug;35(8):1843-51. doi: 10.1161/ATVBAHA.115.305736. Epub 2015 Jun 11.

19.

CaV1.2/CaV3.x channels mediate divergent vasomotor responses in human cerebral arteries.

Harraz OF, Visser F, Brett SE, Goldman D, Zechariah A, Hashad AM, Menon BK, Watson T, Starreveld Y, Welsh DG.

J Gen Physiol. 2015 May;145(5):405-18. doi: 10.1085/jgp.201511361.

20.

TRPV4 channel cooperativity in the resistance vasculature.

Welsh DG.

Biophys J. 2015 Mar 24;108(6):1312-1313. doi: 10.1016/j.bpj.2015.01.035. No abstract available.

21.

Feed the brain: insights into the study of neurovascular coupling.

Welsh DG, Ledoux J.

Microcirculation. 2015 Apr;22(3):157-8. doi: 10.1111/micc.12199.

PMID:
25771945
22.

Localized TRPA1 channel Ca2+ signals stimulated by reactive oxygen species promote cerebral artery dilation.

Sullivan MN, Gonzales AL, Pires PW, Bruhl A, Leo MD, Li W, Oulidi A, Boop FA, Feng Y, Jaggar JH, Welsh DG, Earley S.

Sci Signal. 2015 Jan 6;8(358):ra2. doi: 10.1126/scisignal.2005659.

23.

Origins of variation in conducted vasomotor responses.

Hald BO, Welsh DG, Holstein-Rathlou NH, Jacobsen JC.

Pflugers Arch. 2015 Oct;467(10):2055-67. doi: 10.1007/s00424-014-1649-1. Epub 2014 Nov 26.

PMID:
25420525
24.

Gap junctions suppress electrical but not [Ca(2+)] heterogeneity in resistance arteries.

Hald BO, Welsh DG, Holstein-Rathlou NH, Jacobsen JC.

Biophys J. 2014 Nov 18;107(10):2467-76. doi: 10.1016/j.bpj.2014.09.036.

25.

Ca(V)3.2 channels and the induction of negative feedback in cerebral arteries.

Harraz OF, Abd El-Rahman RR, Bigdely-Shamloo K, Wilson SM, Brett SE, Romero M, Gonzales AL, Earley S, Vigmond EJ, Nygren A, Menon BK, Mufti RE, Watson T, Starreveld Y, Furstenhaupt T, Muellerleile PR, Kurjiaka DT, Kyle BD, Braun AP, Welsh DG.

Circ Res. 2014 Sep 12;115(7):650-61. doi: 10.1161/CIRCRESAHA.114.304056. Epub 2014 Aug 1.

26.

Emerging trend in second messenger communication and myoendothelial feedback.

Tran CH, Kurjiaka DT, Welsh DG.

Front Physiol. 2014 Jun 30;5:243. doi: 10.3389/fphys.2014.00243. eCollection 2014.

27.

Less is more: minimal expression of myoendothelial gap junctions optimizes cell-cell communication in virtual arterioles.

Hald BO, Jacobsen JC, Sandow SL, Holstein-Rathlou NH, Welsh DG.

J Physiol. 2014 Aug 1;592(15):3243-55. doi: 10.1113/jphysiol.2014.272815. Epub 2014 Jun 6.

28.

Nitric oxide suppresses vascular voltage-gated T-type Ca2+ channels through cGMP/PKG signaling.

Harraz OF, Brett SE, Welsh DG.

Am J Physiol Heart Circ Physiol. 2014 Jan 15;306(2):H279-85. doi: 10.1152/ajpheart.00743.2013. Epub 2013 Nov 15.

29.

Protein kinase A regulation of T-type Ca2+ channels in rat cerebral arterial smooth muscle.

Harraz OF, Welsh DG.

J Cell Sci. 2013 Jul 1;126(Pt 13):2944-54. doi: 10.1242/jcs.128363. Epub 2013 Apr 23.

30.

The many faces of Orai.

Welsh DG.

Circ Res. 2013 Mar 29;112(7):983-4. doi: 10.1161/CIRCRESAHA.113.301052. No abstract available.

PMID:
23538273
31.

Leptomeningeal collaterals are associated with modifiable metabolic risk factors.

Menon BK, Smith EE, Coutts SB, Welsh DG, Faber JE, Goyal M, Hill MD, Demchuk AM, Damani Z, Cho KH, Chang HW, Hong JH, Sohn SI.

Ann Neurol. 2013 Aug;74(2):241-8. doi: 10.1002/ana.23906. Epub 2013 Sep 4.

32.

Role of microprojections in myoendothelial feedback--a theoretical study.

Nagaraja S, Kapela A, Tran CH, Welsh DG, Tsoukias NM.

J Physiol. 2013 Jun 1;591(11):2795-812. doi: 10.1113/jphysiol.2012.248948. Epub 2013 Mar 25.

33.

T-type Ca²⁺ channels in cerebral arteries: approaches, hypotheses, and speculation.

Harraz OF, Welsh DG.

Microcirculation. 2013 May;20(4):299-306. doi: 10.1111/micc.12038. Review.

PMID:
23331671
34.

Identification of L- and T-type Ca2+ channels in rat cerebral arteries: role in myogenic tone development.

Abd El-Rahman RR, Harraz OF, Brett SE, Anfinogenova Y, Mufti RE, Goldman D, Welsh DG.

Am J Physiol Heart Circ Physiol. 2013 Jan 1;304(1):H58-71. doi: 10.1152/ajpheart.00476.2012. Epub 2012 Oct 26.

35.

Electrical communication in branching arterial networks.

Tran CH, Vigmond EJ, Goldman D, Plane F, Welsh DG.

Am J Physiol Heart Circ Physiol. 2012 Sep 15;303(6):H680-92. doi: 10.1152/ajpheart.00261.2012. Epub 2012 Jul 13.

36.

Cell-cell communication in the resistance vasculature: the past, present, and future.

Welsh DG, Taylor MS.

Microcirculation. 2012 Jul;19(5):377-8. doi: 10.1111/j.1549-8719.2012.00195.x. Review.

PMID:
22640016
37.

Endothelial feedback and the myoendothelial projection.

Kerr PM, Tam R, Ondrusova K, Mittal R, Narang D, Tran CH, Welsh DG, Plane F.

Microcirculation. 2012 Jul;19(5):416-22. doi: 10.1111/j.1549-8719.2012.00187.x. Review.

PMID:
22533804
38.

Calcium and endothelium-mediated vasodilator signaling.

Sandow SL, Senadheera S, Grayson TH, Welsh DG, Murphy TV.

Adv Exp Med Biol. 2012;740:811-31. doi: 10.1007/978-94-007-2888-2_36. Review.

PMID:
22453971
39.

Endothelial Ca2+ wavelets and the induction of myoendothelial feedback.

Tran CH, Taylor MS, Plane F, Nagaraja S, Tsoukias NM, Solodushko V, Vigmond EJ, Furstenhaupt T, Brigdan M, Welsh DG.

Am J Physiol Cell Physiol. 2012 Apr 15;302(8):C1226-42. doi: 10.1152/ajpcell.00418.2011. Epub 2012 Jan 25.

40.

Do TRPC-like currents and G protein-coupled receptors interact to facilitate myogenic tone development?

Anfinogenova Y, Brett SE, Walsh MP, Harraz OF, Welsh DG.

Am J Physiol Heart Circ Physiol. 2011 Oct;301(4):H1378-88. doi: 10.1152/ajpheart.00460.2011. Epub 2011 Aug 5.

41.

Role of myosin light chain kinase and myosin light chain phosphatase in the resistance arterial myogenic response to intravascular pressure.

Cole WC, Welsh DG.

Arch Biochem Biophys. 2011 Jun 15;510(2):160-73. doi: 10.1016/j.abb.2011.02.024. Epub 2011 Mar 21. Review.

PMID:
21392499
42.

Protein kinases modulate store-operated channels in pulmonary artery smooth muscle cells.

Chen IS, Dai ZK, Welsh DG, Chen IJ, Wu BN.

J Biomed Sci. 2011 Jan 6;18:2. doi: 10.1186/1423-0127-18-2.

43.

Intravascular pressure augments cerebral arterial constriction by inducing voltage-insensitive Ca2+ waves.

Mufti RE, Brett SE, Tran CH, Abd El-Rahman R, Anfinogenova Y, El-Yazbi A, Cole WC, Jones PP, Chen SR, Welsh DG.

J Physiol. 2010 Oct 15;588(Pt 20):3983-4005. doi: 10.1113/jphysiol.2010.193300. Epub 2010 Aug 24.

44.

Modeling the role of the coronary vasculature during external field stimulation.

Bishop MJ, Boyle PM, Plank G, Welsh DG, Vigmond EJ.

IEEE Trans Biomed Eng. 2010 Oct;57(10):2335-45. doi: 10.1109/TBME.2010.2051227. Epub 2010 Jun 10.

45.

The differential hypothesis: a provocative rationalization of the conducted vasomotor response.

Tran CH, Welsh DG.

Microcirculation. 2010 Apr;17(3):226-36. doi: 10.1111/j.1549-8719.2010.00022.x. Review.

PMID:
20374485
46.

Rho-kinase-mediated suppression of KDR current in cerebral arteries requires an intact actin cytoskeleton.

Luykenaar KD, El-Rahman RA, Walsh MP, Welsh DG.

Am J Physiol Heart Circ Physiol. 2009 Apr;296(4):H917-26. doi: 10.1152/ajpheart.01206.2008. Epub 2009 Feb 13.

47.

Mechanistic basis of differential conduction in skeletal muscle arteries.

Tran CH, Vigmond EJ, Plane F, Welsh DG.

J Physiol. 2009 Mar 15;587(Pt 6):1301-18. doi: 10.1113/jphysiol.2008.166017. Epub 2009 Jan 26.

48.

Current perspective on differential communication in small resistance arteries.

Tran CH, Welsh DG.

Can J Physiol Pharmacol. 2009 Jan;87(1):21-8. doi: 10.1139/Y08-104.

PMID:
19142212
49.

What's where and why at a vascular myoendothelial microdomain signalling complex.

Sandow SL, Haddock RE, Hill CE, Chadha PS, Kerr PM, Welsh DG, Plane F.

Clin Exp Pharmacol Physiol. 2009 Jan;36(1):67-76. doi: 10.1111/j.1440-1681.2008.05076.x. Epub 2008 Oct 31. Review.

PMID:
19018806
50.

KIR channels function as electrical amplifiers in rat vascular smooth muscle.

Smith PD, Brett SE, Luykenaar KD, Sandow SL, Marrelli SP, Vigmond EJ, Welsh DG.

J Physiol. 2008 Feb 15;586(4):1147-60. Epub 2007 Dec 6.

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