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Items: 1 to 50 of 1192

1.

Improving translatability of preclinical studies for neuromuscular disorders: lessons from the TREAT-NMD Advisory Committee for Therapeutics (TACT).

Willmann R, Lee J, Turner C, Nagaraju K, Aartsma-Rus A, Wells DJ, Wagner KR, Csimma C, Straub V, Grounds MD, De Luca A.

Dis Model Mech. 2020 Feb 7;13(2). pii: dmm042903. doi: 10.1242/dmm.042903. Review.

2.

Circulating tumor DNA analysis to assess risk of progression after long-term response to PD-(L)1 blockade in NSCLC.

Hellmann MD, Nabet BY, Rizvi H, Chaudhuri AA, Wells DK, Dunphy MP, Chabon JJ, Liu CL, Hui AB, Arbour KC, Luo J, Preeshagul IR, Moding EJ, Almanza D, Bonilla RF, Sauter JL, Choi H, Tenet M, Abu-Akeel M, Plodkowski AJ, Perez-Johnston R, Yoo CH, Ko RB, Stehr H, Gojenola L, Wakelee HA, Padda SK, Neal JW, Chaft JE, Kris MG, Rudin CM, Merghoub T, Li BT, Alizadeh AA, Diehn M.

Clin Cancer Res. 2020 Feb 11. pii: clincanres.3418.2019. doi: 10.1158/1078-0432.CCR-19-3418. [Epub ahead of print]

PMID:
32046999
3.

Variations in hemoglobin measurement and eligibility criteria across blood donation services are associated with differing low-hemoglobin deferral rates: a BEST Collaborative study.

Zalpuri S, Romeijn B, Allara E, Goldman M, Kamel H, Gorlin J, Vassallo R, Grégoire Y, Goto N, Flanagan P, Speedy J, Buser A, Kutner JM, Magnussen K, Castrén J, Culler L, Sussmann H, Prinsze FJ, Belanger K, Compernolle V, Tiberghien P, Cardenas JM, Gandhi MJ, West KA, Lee CK, James S, Wells D, Sutor LJ, Wendel S, Coleman M, Seltsam A, Roden K, Steele WR, Bohonek M, Alcantara R, Di Angelantonio E, van den Hurk K; BEST Collaborative Study Group .

Transfusion. 2020 Feb 8. doi: 10.1111/trf.15676. [Epub ahead of print]

PMID:
32034925
4.

Sperm Mitochondrial DNA Copy Number Is Not a Predictor of Intracytoplasmic Sperm Injection (ICSI) Cycle Outcomes.

Tiegs AW, Tao X, Landis J, Zhan Y, Franasiak JM, Seli E, Wells D, Fragouli E, Scott RT Jr.

Reprod Sci. 2020 Jan 28. doi: 10.1007/s43032-020-00163-0. [Epub ahead of print]

PMID:
31994001
5.

Dynamic Shifts in the HIV Proviral Landscape During Long Term Combination Antiretroviral Therapy: Implications for Persistence and Control of HIV Infections.

Anderson EM, Simonetti FR, Gorelick RJ, Hill S, Gouzoulis MA, Bell J, Rehm C, Pérez L, Boritz E, Wu X, Wells D, Hughes SH, Rao V, Coffin JM, Kearney MF, Maldarelli F.

Viruses. 2020 Jan 25;12(2). pii: E136. doi: 10.3390/v12020136.

6.

Establishment of porcine nuclear transfer-derived embryonic stem cells using induced pluripotent stem cells as donor nuclei.

Haraguchi S, Dang-Nguyen TQ, Wells D, Fuchimoto D, Fukuda T, Tokunaga T.

J Reprod Dev. 2020 Jan 26. doi: 10.1262/jrd.2019-137. [Epub ahead of print]

7.

A decade of optimizing drug development for rare neuromuscular disorders through TACT.

Wagner KR, De Luca A, Caizergues D, Dowling J, Goemans N, Gordish-Dressman H, Grounds MD, Kelly M, Mayhew A, McNally EM, Zoetis T, Lee J, Turner C, Wells DJ, Csimma C, Straub V.

Nat Rev Drug Discov. 2020 Jan;19(1):1-2. doi: 10.1038/d41573-019-00199-1. No abstract available.

PMID:
31907422
8.

Patient and caregiver priorities in the transition from hospital to home: results from province-wide group concept mapping.

Kiran T, Wells D, Okrainec K, Kennedy C, Devotta K, Mabaya G, Phillips L, Lang A, O'Campo P.

BMJ Qual Saf. 2020 Jan 5. pii: bmjqs-2019-009993. doi: 10.1136/bmjqs-2019-009993. [Epub ahead of print]

PMID:
31907325
9.

Comparison of naloxone prescribing patterns due to educational outreach conducted by full-time and part-time academic detailers at the U.S. Veterans Health Administration.

Bounthavong M, Harvey MA, Kay CL, Lau MK, Wells DL, Himstreet JE, Popish SJ, Oliva EM, Christopher MLD.

J Am Pharm Assoc (2003). 2019 Dec 19. pii: S1544-3191(19)30516-3. doi: 10.1016/j.japh.2019.11.010. [Epub ahead of print]

PMID:
31866383
10.

Comparing deep learning-based auto-segmentation of organs at risk and clinical target volumes to expert inter-observer variability in radiotherapy planning.

Wong J, Fong A, McVicar N, Smith S, Giambattista J, Wells D, Kolbeck C, Giambattista J, Gondara L, Alexander A.

Radiother Oncol. 2019 Dec 5;144:152-158. doi: 10.1016/j.radonc.2019.10.019. [Epub ahead of print]

PMID:
31812930
11.

Non-invasive preimplantation genetic testing (niPGT): the next revolution in reproductive genetics?

Leaver M, Wells D.

Hum Reprod Update. 2020 Jan 1;26(1):16-42. doi: 10.1093/humupd/dmz033.

PMID:
31774124
12.

Evaluation of Cord Blood Total Nucleated and CD34+ Cell Content, Cell Dose, and 8-Allele HLA Match by Patient Ancestry.

Barker JN, Mazis CM, Devlin SM, Davis E, Maloy MA, Naputo K, Nhaissi M, Wells D, Scaradavou A, Politikos I.

Biol Blood Marrow Transplant. 2019 Nov 19. pii: S1083-8791(19)30784-0. doi: 10.1016/j.bbmt.2019.11.017. [Epub ahead of print]

PMID:
31756534
13.

Corrigendum: The Spectrum of SPTA1-Associated Hereditary Spherocytosis.

Chonat S, Risinger M, Sakthivel H, Niss O, Rothman JA, Hsieh L, Chou ST, Kwiatkowski JL, Khandros E, Gorman MF, Wells DT, Maghathe T, Dagaonkar N, Seu KG, Zhang K, Zhang W, Kalfa TA.

Front Physiol. 2019 Oct 18;10:1331. doi: 10.3389/fphys.2019.01331. eCollection 2019.

14.

RootNav 2.0: Deep learning for automatic navigation of complex plant root architectures.

Yasrab R, Atkinson JA, Wells DM, French AP, Pridmore TP, Pound MP.

Gigascience. 2019 Nov 1;8(11). pii: giz123. doi: 10.1093/gigascience/giz123.

15.

Preimplantation genetic screening should be used in all in vitro fertilisation cycles in women over the age of 35 years: FOR: Optimising reproductive outcomes is cost-effective and minimises adverse sequelae.

Ben Nagi J, Serhal P, Wells D, Jones BP.

BJOG. 2019 Dec;126(13):1554. doi: 10.1111/1471-0528.15941. Epub 2019 Oct 14. No abstract available.

PMID:
31612560
16.

Which orthopaedic trauma patients are likely to refuse to participate in a clinical trial? A latent class analysis.

O'Hara NN, Degani Y, Marvel D, Wells D, Mullins CD, Wegener S, Frey K, Joseph T, Hurst J, Castillo R, O'Toole RV; PREVENT CLOT Stakeholder Committee.

BMJ Open. 2019 Oct 11;9(10):e032631. doi: 10.1136/bmjopen-2019-032631.

17.

Author Correction: Rice plants overexpressing OsEPF1 show reduced stomatal density and increased root cortical aerenchyma formation.

Mohammed U, Caine RS, Atkinson JA, Harrison EL, Wells D, Chater CC, Gray JE, Swarup R, Murchie EH.

Sci Rep. 2019 Oct 10;9(1):14827. doi: 10.1038/s41598-019-51402-7.

18.

A national quality improvement programme to improve survival after emergency abdominal surgery: the EPOCH stepped-wedge cluster RCT.

Peden CJ, Stephens T, Martin G, Kahan BC, Thomson A, Everingham K, Kocman D, Lourtie J, Drake S, Girling A, Lilford R, Rivett K, Wells D, Mahajan R, Holt P, Yang F, Walker S, Richardson G, Kerry S, Anderson I, Murray D, Cromwell D, Phull M, Grocott MPW, Bion J, Pearse RM; the EPOCH trial group .

Southampton (UK): NIHR Journals Library; 2019 Sep.

19.

Preimplantation genetic testing for aneuploidy versus morphology as selection criteria for single frozen-thawed embryo transfer in good-prognosis patients: a multicenter randomized clinical trial.

Munné S, Kaplan B, Frattarelli JL, Child T, Nakhuda G, Shamma FN, Silverberg K, Kalista T, Handyside AH, Katz-Jaffe M, Wells D, Gordon T, Stock-Myer S, Willman S; STAR Study Group.

Fertil Steril. 2019 Dec;112(6):1071-1079.e7. doi: 10.1016/j.fertnstert.2019.07.1346. Epub 2019 Sep 21.

PMID:
31551155
20.

Improving Engagement with Biomechanics: Student Perspectives and A Professional Development Initiative.

Shultz SP, Millar SK, Fink P, Hébert-Losier K, Handsfield G, Sheerin K, Wells D, Clarke J.

J Biomech Eng. 2019 Sep 1. doi: 10.1115/1.4044782. [Epub ahead of print]

PMID:
31518430
21.

Laterality as a Tool for Assessing Breed Differences in Emotional Reactivity in the Domestic Cat, Felis silvestris catus.

Wells DL, McDowell LJ.

Animals (Basel). 2019 Sep 3;9(9). pii: E647. doi: 10.3390/ani9090647.

22.

Divining the genetic status of embryos: consult the medium?

Babariya D, Leaver M, Wells D.

Fertil Steril. 2019 Sep;112(3):471-473. doi: 10.1016/j.fertnstert.2019.06.012. Epub 2019 Jul 29. No abstract available.

PMID:
31371043
23.

HIV-1 in lymph nodes is maintained by cellular proliferation during antiretroviral therapy.

McManus WR, Bale MJ, Spindler J, Wiegand A, Musick A, Patro SC, Sobolewski MD, Musick VK, Anderson EM, Cyktor JC, Halvas EK, Shao W, Wells D, Wu X, Keele BF, Milush JM, Hoh R, Mellors JW, Hughes SH, Deeks SG, Coffin JM, Kearney MF.

J Clin Invest. 2019 Jul 30;130:4629-4642. doi: 10.1172/JCI126714.

24.

Clonal replacement of tumor-specific T cells following PD-1 blockade.

Yost KE, Satpathy AT, Wells DK, Qi Y, Wang C, Kageyama R, McNamara KL, Granja JM, Sarin KY, Brown RA, Gupta RK, Curtis C, Bucktrout SL, Davis MM, Chang ALS, Chang HY.

Nat Med. 2019 Aug;25(8):1251-1259. doi: 10.1038/s41591-019-0522-3. Epub 2019 Jul 29.

25.

The Spectrum of SPTA1-Associated Hereditary Spherocytosis.

Chonat S, Risinger M, Sakthivel H, Niss O, Rothman JA, Hsieh L, Chou ST, Kwiatkowski JL, Khandros E, Gorman MF, Wells DT, Maghathe T, Dagaonkar N, Seu KG, Zhang K, Zhang W, Kalfa TA.

Front Physiol. 2019 Jul 3;10:815. doi: 10.3389/fphys.2019.00815. eCollection 2019. Erratum in: Front Physiol. 2019 Oct 18;10:1331.

26.

Deciphering the Significance of CD56 Expression in Pediatric Acute Myeloid Leukemia: A Report from the Children's Oncology Group.

Pardo LM, Voigt AP, Alonzo TA, Wilson ER, Gerbing RB, Paine DJ, Dai F, Menssen AJ, Raimondi SC, Hirsch BA, Gamis AS, Meshinchi S, Wells DA, Brodersen LE, Loken MR.

Cytometry B Clin Cytom. 2020 Jan;98(1):52-56. doi: 10.1002/cyto.b.21829. Epub 2019 Jul 11.

PMID:
31294507
27.

Clonal expansion of SIV-infected cells in macaques on antiretroviral therapy is similar to that of HIV-infected cells in humans.

Ferris AL, Wells DW, Guo S, Del Prete GQ, Swanstrom AE, Coffin JM, Wu X, Lifson JD, Hughes SH.

PLoS Pathog. 2019 Jul 10;15(7):e1007869. doi: 10.1371/journal.ppat.1007869. eCollection 2019 Jul.

28.

What is the level of dystrophin expression required for effective therapy of Duchenne muscular dystrophy?

Wells DJ.

J Muscle Res Cell Motil. 2019 Jun;40(2):141-150. doi: 10.1007/s10974-019-09535-9. Epub 2019 Jul 9.

PMID:
31289969
29.

Unified single-cell analysis of testis gene regulation and pathology in five mouse strains.

Jung M, Wells D, Rusch J, Ahmad S, Marchini J, Myers SR, Conrad DF.

Elife. 2019 Jun 25;8. pii: e43966. doi: 10.7554/eLife.43966.

30.

Clones of infected cells arise early in HIV-infected individuals.

Coffin JM, Wells DW, Zerbato JM, Kuruc JD, Guo S, Luke BT, Eron JJ, Bale M, Spindler J, Simonetti FR, Hill S, Kearney MF, Maldarelli F, Wu X, Mellors JW, Hughes SH.

JCI Insight. 2019 Jun 20;4(12). pii: 128432. doi: 10.1172/jci.insight.128432. eCollection 2019 Jun 20.

31.

Tumor Characteristics Associated with Benefit from Pembrolizumab in Advanced Non-Small Cell Lung Cancer.

Hu-Lieskovan S, Lisberg A, Zaretsky JM, Grogan TR, Rizvi H, Wells DK, Carroll J, Cummings A, Madrigal J, Jones B, Gukasyan J, Shintaku IP, Slamon D, Dubinett S, Goldman JW, Elashoff D, Hellmann MD, Ribas A, Garon EB.

Clin Cancer Res. 2019 Aug 15;25(16):5061-5068. doi: 10.1158/1078-0432.CCR-18-4275. Epub 2019 May 21.

32.

Effectiveness of a national quality improvement programme to improve survival after emergency abdominal surgery (EPOCH): a stepped-wedge cluster-randomised trial.

Peden CJ, Stephens T, Martin G, Kahan BC, Thomson A, Rivett K, Wells D, Richardson G, Kerry S, Bion J, Pearse RM; Enhanced Peri-Operative Care for High-risk patients (EPOCH) trial group.

Lancet. 2019 Jun 1;393(10187):2213-2221. doi: 10.1016/S0140-6736(18)32521-2. Epub 2019 Apr 25.

33.

Active Vision and Surface Reconstruction for 3D Plant Shoot Modelling.

Gibbs JA, Pound M, French A, Wells D, Murchie E, Pridmore T.

IEEE/ACM Trans Comput Biol Bioinform. 2019 Apr 25. doi: 10.1109/TCBB.2019.2896908. [Epub ahead of print]

PMID:
31027044
34.

Rice plants overexpressing OsEPF1 show reduced stomatal density and increased root cortical aerenchyma formation.

Mohammed U, Caine RS, Atkinson JA, Harrison EL, Wells D, Chater CC, Gray JE, Swarup R, Murchie EH.

Sci Rep. 2019 Apr 3;9(1):5584. doi: 10.1038/s41598-019-41922-7. Erratum in: Sci Rep. 2019 Oct 10;9(1):14827.

35.

Racial disparities in access to HLA-matched unrelated donor transplants: a prospective 1312-patient analysis.

Barker JN, Boughan K, Dahi PB, Devlin SM, Maloy MA, Naputo K, Mazis CM, Davis E, Nhaissi M, Wells D, Cooper C, Ponce DM, Kernan N, Scaradavou A, Giralt SA, Papadopoulos EB, Politikos I.

Blood Adv. 2019 Apr 9;3(7):939-944. doi: 10.1182/bloodadvances.2018028662.

36.

Can research align with service? Lessons learned from the Big Experiment and National Biomechanics Day.

Shultz SP, Hughes-Oliver C, Wells D, Sheerin K, Fink PW, Handsfield GG, Hébert-Losier K, Clarke J, Queen RM.

J Biomech. 2019 Apr 18;87:202-205. doi: 10.1016/j.jbiomech.2019.03.006. Epub 2019 Mar 16.

PMID:
30910361
37.

Corrigendum. Mitochondrial DNA quantification as a tool for embryo viability assessment: retrospective analysis of data from single euploid blastocyst transfers.

Ravichandran K, McCaffrey C, Grifo J, Morales A, Perloe M, Munne S, Wells D, Fragouli E.

Hum Reprod. 2019 Apr 1;34(4):781. doi: 10.1093/humrep/dez013. No abstract available.

PMID:
30888030
38.

Impact of academic detailing on benzodiazepine use among veterans with posttraumatic stress disorder.

Bounthavong M, Lau MK, Popish SJ, Kay CL, Wells DL, Himstreet JE, Harvey MA, Christopher MLD.

Subst Abus. 2019 Mar 14:1-9. doi: 10.1080/08897077.2019.1573777. [Epub ahead of print]

PMID:
30870137
39.

Corrigendum. Clinical implications of mitochondrial DNA quantification on pregnancy outcomes: a blinded prospective non-selection study.

Fragouli E, McCaffrey C, Ravichandran K, Spath K, Grifo JA, Munné S, Wells D.

Hum Reprod. 2019 Apr 1;34(4):782. doi: 10.1093/humrep/dez014. No abstract available.

PMID:
30865263
40.

The First ongoing Pregnancy Following Comprehensive Aneuploidy Assessment Using a Combined Blastocenetesis, Cell Free DNA and Trophectoderm Biopsy Strategy.

Ben-Nagi J, Odia R, Gonzalez XV, Heath C, Babariya D, SenGupta S, Serhal P, Wells D.

J Reprod Infertil. 2019 Jan-Mar;20(1):57-62.

41.

Current Controversies in Prenatal Diagnosis 3: Gene editing should replace embryo selection following PGD.

Wells D, Vermeesch JR, Simpson JL.

Prenat Diagn. 2019 Apr;39(5):344-350. doi: 10.1002/pd.5442. No abstract available.

PMID:
30834542
42.

It Is a Capital Mistake to Theorize Who to Treat with Checkpoint Inhibitors before One Has Data.

Spencer CN, Wells DK, LaVallee TM.

Trends Cancer. 2019 Feb;5(2):79-82. doi: 10.1016/j.trecan.2018.12.003. Epub 2019 Jan 11.

PMID:
30755306
43.

Identification of qPCR reference genes suitable for normalizing gene expression in the mdx mouse model of Duchenne muscular dystrophy.

Hildyard JCW, Finch AM, Wells DJ.

PLoS One. 2019 Jan 30;14(1):e0211384. doi: 10.1371/journal.pone.0211384. eCollection 2019.

44.

Episomal minicircles persist in periods of transcriptional inactivity and can be transmitted through somatic cell nuclear transfer into bovine embryos.

Wagner S, McCracken J, Bruszies S, Broadhurst R, Wells DN, Oback B, Bode J, Laible G.

Mol Biol Rep. 2019 Apr;46(2):1737-1746. doi: 10.1007/s11033-019-04624-x. Epub 2019 Jan 29.

PMID:
30694456
45.

A fast and adaptable method for high accuracy integration of the time-dependent Schrödinger equation.

Wells D, Quiney H.

Sci Rep. 2019 Jan 28;9(1):782. doi: 10.1038/s41598-018-37382-0.

46.

The cytogenetic constitution of human blastocysts: insights from comprehensive chromosome screening strategies.

Fragouli E, Munne S, Wells D.

Hum Reprod Update. 2019 Jan 1;25(1):15-33. doi: 10.1093/humupd/dmy036.

PMID:
30395265
47.

Publisher Correction: Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma.

Amaria RN, Reddy SM, Tawbi HA, Davies MA, Ross MI, Glitza IC, Cormier JN, Lewis C, Hwu WJ, Hanna E, Diab A, Wong MK, Royal R, Gross N, Weber R, Lai SY, Ehlers R, Blando J, Milton DR, Woodman S, Kageyama R, Wells DK, Hwu P, Patel SP, Lucci A, Hessel A, Lee JE, Gershenwald J, Simpson L, Burton EM, Posada L, Haydu L, Wang L, Zhang S, Lazar AJ, Hudgens CW, Gopalakrishnan V, Reuben A, Andrews MC, Spencer CN, Prieto V, Sharma P, Allison J, Tetzlaff MT, Wargo JA.

Nat Med. 2018 Dec;24(12):1942. doi: 10.1038/s41591-018-0252-y.

PMID:
30361511
48.

Author Correction: Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma.

Amaria RN, Reddy SM, Tawbi HA, Davies MA, Ross MI, Glitza IC, Cormier JN, Lewis C, Hwu WJ, Hanna E, Diab A, Wong MK, Royal R, Gross N, Weber R, Lai SY, Ehlers R, Blando J, Milton DR, Woodman S, Kageyama R, Wells DK, Hwu P, Patel SP, Lucci A, Hessel A, Lee JE, Gershenwald J, Simpson L, Burton EM, Posada L, Haydu L, Wang L, Zhang S, Lazar AJ, Hudgens CW, Gopalakrishnan V, Reuben A, Andrews MC, Spencer CN, Prieto V, Sharma P, Allison J, Tetzlaff MT, Wargo JA.

Nat Med. 2018 Dec;24(12):1941. doi: 10.1038/s41591-018-0251-z.

PMID:
30361510
49.

Pores for thought: preimplantation genetic testing using a nanopore-based DNA sequencer.

Fragouli E, Wells D.

Fertil Steril. 2018 Oct;110(5):853-855. doi: 10.1016/j.fertnstert.2018.07.015. No abstract available.

PMID:
30316429
50.

Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma.

Amaria RN, Reddy SM, Tawbi HA, Davies MA, Ross MI, Glitza IC, Cormier JN, Lewis C, Hwu WJ, Hanna E, Diab A, Wong MK, Royal R, Gross N, Weber R, Lai SY, Ehlers R, Blando J, Milton DR, Woodman S, Kageyama R, Wells DK, Hwu P, Patel SP, Lucci A, Hessel A, Lee JE, Gershenwald J, Simpson L, Burton EM, Posada L, Haydu L, Wang L, Zhang S, Lazar AJ, Hudgens CW, Gopalakrishnan V, Reuben A, Andrews MC, Spencer CN, Prieto V, Sharma P, Allison J, Tetzlaff MT, Wargo JA.

Nat Med. 2018 Nov;24(11):1649-1654. doi: 10.1038/s41591-018-0197-1. Epub 2018 Oct 8. Erratum in: Nat Med. 2018 Oct 25;:. Nat Med. 2018 Oct 25;:.

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