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Items: 1 to 50 of 115

1.

Alternative transcription cycle for bacterial RNA polymerase.

Harden TT, Herlambang KS, Chamberlain M, Lalanne JB, Wells CD, Li GW, Landick R, Hochschild A, Kondev J, Gelles J.

Nat Commun. 2020 Jan 23;11(1):448. doi: 10.1038/s41467-019-14208-9.

2.

Out of the Blue: The Failure of the Introduced Sea Anemone Sagartia elegans (Dalyell, 1848) in Salem Harbor, Massachusetts.

Wells CD, Harris LG.

Biol Bull. 2019 Dec;237(3):283-291. doi: 10.1086/705515. Epub 2019 Dec 9.

PMID:
31922904
3.

Progressive fibrosing interstitial lung diseases: current practice in diagnosis and management.

Wijsenbeek M, Kreuter M, Olson A, Fischer A, Bendstrup E, Wells CD, Denton CP, Mounir B, Zouad-Lejour L, Quaresma M, Cottin V.

Curr Med Res Opin. 2019 Nov;35(11):2015-2024. doi: 10.1080/03007995.2019.1647040. Epub 2019 Aug 2.

PMID:
31328965
4.

Identification of Specific Lysines and Arginines That Mediate Angiomotin Membrane Association.

Hall L, Donovan E, Araya M, Idowa E, Jiminez-Segovia I, Folck A, Wells CD, Kimble-Hill AC.

ACS Omega. 2019 Apr 30;4(4):6726-6736. doi: 10.1021/acsomega.9b00165. Epub 2019 Apr 12.

5.

HIV-associated cavernous sinus disease.

Wells CD, Moodley AA.

South Afr J HIV Med. 2019 Mar 20;20(1):862. doi: 10.4102/sajhivmed.v20i1.862. eCollection 2019.

6.

COPD and asthma: Diagnostic accuracy requires spirometry.

Wells CD, Joo MJ.

J Fam Pract. 2019 Mar;68(2):76-81.

PMID:
30870534
7.

Small-Molecule Covalent Modification of Conserved Cysteine Leads to Allosteric Inhibition of the TEAD⋅Yap Protein-Protein Interaction.

Bum-Erdene K, Zhou D, Gonzalez-Gutierrez G, Ghozayel MK, Si Y, Xu D, Shannon HE, Bailey BJ, Corson TW, Pollok KE, Wells CD, Meroueh SO.

Cell Chem Biol. 2019 Mar 21;26(3):378-389.e13. doi: 10.1016/j.chembiol.2018.11.010. Epub 2018 Dec 20.

PMID:
30581134
8.

Pan-tuberculosis regimens: re-framing the argument.

Gupta R, Wells CD.

Lancet Respir Med. 2018 Jul;6(7):e28. doi: 10.1016/S2213-2600(18)30189-9. No abstract available.

PMID:
29976444
9.

Reply to Jacob and Colebunders.

Ellenberg SS, Keusch GT, Babiker AG, Edwards KM, Lewis RJ, Lundgren JD, Wells CD, Wabwire-Mangen F, McAdam KPWJ.

Clin Infect Dis. 2018 Aug 31;67(6):985-986. doi: 10.1093/cid/ciy250. No abstract available.

PMID:
29590323
10.

Rigorous Clinical Trial Design in Public Health Emergencies Is Essential.

Ellenberg SS, Keusch GT, Babiker AG, Edwards KM, Lewis RJ, Lundgren JD, Wells CD, Wabwire-Mangen F, McAdam KPWJ.

Clin Infect Dis. 2018 Apr 17;66(9):1467-1469. doi: 10.1093/cid/cix1032.

11.
12.

Delamanid in the treatment of multidrug-resistant tuberculosis.

Gupta R, Wells CD, Hittel N, Hafkin J, Geiter LJ.

Int J Tuberc Lung Dis. 2016 Dec 1;20(12):33-37. doi: 10.5588/ijtld.16.0125. Review.

PMID:
28240570
13.

Combination therapy in a xenograft model of glioblastoma: enhancement of the antitumor activity of temozolomide by an MDM2 antagonist.

Wang H, Cai S, Bailey BJ, Reza Saadatzadeh M, Ding J, Tonsing-Carter E, Georgiadis TM, Zachary Gunter T, Long EC, Minto RE, Gordon KR, Sen SE, Cai W, Eitel JA, Waning DL, Bringman LR, Wells CD, Murray ME, Sarkaria JN, Gelbert LM, Jones DR, Cohen-Gadol AA, Mayo LD, Shannon HE, Pollok KE.

J Neurosurg. 2017 Feb;126(2):446-459. doi: 10.3171/2016.1.JNS152513. Epub 2016 May 13.

14.

Nascent RNA length dictates opposing effects of NusA on antitermination.

Wells CD, Deighan P, Brigham M, Hochschild A.

Nucleic Acids Res. 2016 Jun 20;44(11):5378-89. doi: 10.1093/nar/gkw198. Epub 2016 Mar 28.

15.

Building clinical trial capacity to develop a new treatment for multidrug-resistant tuberculosis.

Tupasi T, Gupta R, Danilovits M, Cirule A, Sanchez-Garavito E, Xiao H, Cabrera-Rivero JL, Vargas-Vasquez DE, Gao M, Awad M, Gentry LM, Geiter LJ, Wells CD.

Bull World Health Organ. 2016 Feb 1;94(2):147-52. doi: 10.2471/BLT.15.154997. Epub 2015 Nov 17.

16.

Bacterial RNA polymerase can retain σ70 throughout transcription.

Harden TT, Wells CD, Friedman LJ, Landick R, Hochschild A, Kondev J, Gelles J.

Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):602-7. doi: 10.1073/pnas.1513899113. Epub 2016 Jan 5.

17.

Delamanid and QT prolongation in the treatment of multidrug-resistant tuberculosis.

Gupta R, Geiter LJ, Hafkin J, Wells CD.

Int J Tuberc Lung Dis. 2015 Oct;19(10):1261-2. doi: 10.5588/ijtld.15.0541. No abstract available.

PMID:
26459547
18.

The primary σ factor in Escherichia coli can access the transcription elongation complex from solution in vivo.

Goldman SR, Nair NU, Wells CD, Nickels BE, Hochschild A.

Elife. 2015 Sep 15;4. doi: 10.7554/eLife.10514.

19.

Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors.

He R, Yu ZH, Zhang RY, Wu L, Gunawan AM, Lane BS, Shim JS, Zeng LF, He Y, Chen L, Wells CD, Liu JO, Zhang ZY.

ACS Med Chem Lett. 2015 Jun 8;6(7):782-6. doi: 10.1021/acsmedchemlett.5b00118. eCollection 2015 Jul 9.

20.

Delamanid for Extensively Drug-Resistant Tuberculosis.

Gupta R, Geiter LJ, Wells CD, Gao M, Cirule A, Xiao H.

N Engl J Med. 2015 Jul 16;373(3):291-2. doi: 10.1056/NEJMc1415332. No abstract available.

21.

The TGF-β Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to Bone.

Fournier PG, Juárez P, Jiang G, Clines GA, Niewolna M, Kim HS, Walton HW, Peng XH, Liu Y, Mohammad KS, Wells CD, Chirgwin JM, Guise TA.

Cancer Cell. 2015 Jun 8;27(6):809-21. doi: 10.1016/j.ccell.2015.04.009. Epub 2015 May 14.

22.

Long-term mortality assessment of multidrug-resistant tuberculosis patients treated with delamanid.

Wells CD, Gupta R, Hittel N, Geiter LJ.

Eur Respir J. 2015 May;45(5):1498-501. doi: 10.1183/09031936.00176314. Epub 2015 Feb 19. No abstract available.

23.

Primary cilia signaling mediates intraocular pressure sensation.

Luo N, Conwell MD, Chen X, Kettenhofen CI, Westlake CJ, Cantor LB, Wells CD, Weinreb RN, Corson TW, Spandau DF, Joos KM, Iomini C, Obukhov AG, Sun Y.

Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12871-6. doi: 10.1073/pnas.1323292111. Epub 2014 Aug 20.

24.

Therapeutic potential of targeting the oncogenic SHP2 phosphatase.

Zeng LF, Zhang RY, Yu ZH, Li S, Wu L, Gunawan AM, Lane BS, Mali RS, Li X, Chan RJ, Kapur R, Wells CD, Zhang ZY.

J Med Chem. 2014 Aug 14;57(15):6594-609. doi: 10.1021/jm5006176. Epub 2014 Jul 28.

25.

Response to letter to the editor.

Dworkin RH, O'Connor AB, Kent J, Mackey SC, Raja SN, Stacey BR, Levy RM, Backonja M, Baron R, Harke H, Loeser JD, Treede RD, Turk DC, Wells CD.

Pain. 2014 May;155(5):1045-6. doi: 10.1016/j.pain.2014.01.029. Epub 2014 Feb 7. No abstract available.

PMID:
24513276
26.

Serum deprivation inhibits the transcriptional co-activator YAP and cell growth via phosphorylation of the 130-kDa isoform of Angiomotin by the LATS1/2 protein kinases.

Adler JJ, Johnson DE, Heller BL, Bringman LR, Ranahan WP, Conwell MD, Sun Y, Hudmon A, Wells CD.

Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17368-73. doi: 10.1073/pnas.1308236110. Epub 2013 Oct 7.

27.

Interventional management of neuropathic pain: NeuPSIG recommendations.

Dworkin RH, O'Connor AB, Kent J, Mackey SC, Raja SN, Stacey BR, Levy RM, Backonja M, Baron R, Harke H, Loeser JD, Treede RD, Turk DC, Wells CD; International Association for the Study of Pain Neuropathic Pain Special Interest Group.

Pain. 2013 Nov;154(11):2249-61. doi: 10.1016/j.pain.2013.06.004. Epub 2013 Jun 6. Review.

28.

Amot130 adapts atrophin-1 interacting protein 4 to inhibit yes-associated protein signaling and cell growth.

Adler JJ, Heller BL, Bringman LR, Ranahan WP, Cocklin RR, Goebl MG, Oh M, Lim HS, Ingham RJ, Wells CD.

J Biol Chem. 2013 May 24;288(21):15181-93. doi: 10.1074/jbc.M112.446534. Epub 2013 Apr 5.

29.

LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap.

Nguyen HB, Babcock JT, Wells CD, Quilliam LA.

Oncogene. 2013 Aug 29;32(35):4100-9. doi: 10.1038/onc.2012.431. Epub 2012 Oct 1.

30.

Delamanid improves outcomes and reduces mortality in multidrug-resistant tuberculosis.

Skripconoka V, Danilovits M, Pehme L, Tomson T, Skenders G, Kummik T, Cirule A, Leimane V, Kurve A, Levina K, Geiter LJ, Manissero D, Wells CD.

Eur Respir J. 2013 Jun;41(6):1393-400. doi: 10.1183/09031936.00125812. Epub 2012 Sep 27.

32.

Delamanid for multidrug-resistant pulmonary tuberculosis.

Gler MT, Skripconoka V, Sanchez-Garavito E, Xiao H, Cabrera-Rivero JL, Vargas-Vasquez DE, Gao M, Awad M, Park SK, Shim TS, Suh GY, Danilovits M, Ogata H, Kurve A, Chang J, Suzuki K, Tupasi T, Koh WJ, Seaworth B, Geiter LJ, Wells CD.

N Engl J Med. 2012 Jun 7;366(23):2151-60. doi: 10.1056/NEJMoa1112433.

33.

Moving toward tuberculosis elimination: implementation of statewide targeted tuberculin testing in Tennessee.

Cain KP, Garman KN, Laserson KF, Ferrousier-Davis OP, Miranda AG, Wells CD, Haley CA.

Am J Respir Crit Care Med. 2012 Aug 1;186(3):273-9. doi: 10.1164/rccm.201111-2076OC. Epub 2012 May 3.

PMID:
22561962
34.

OCRL localizes to the primary cilium: a new role for cilia in Lowe syndrome.

Luo N, West CC, Murga-Zamalloa CA, Sun L, Anderson RM, Wells CD, Weinreb RN, Travers JB, Khanna H, Sun Y.

Hum Mol Genet. 2012 Aug 1;21(15):3333-44. doi: 10.1093/hmg/dds163. Epub 2012 Apr 27.

35.

Bacteriologic monitoring of multidrug-resistant tuberculosis patients in five DOTS-Plus pilot projects.

Gammino VM, Taylor AB, Rich ML, Bayona J, Becerra MC, Bonilla C, Gelmanova I, Hollo V, Jaramillo E, Keshavjee S, Leimane V, Mitnick CD, Quelapio MI, Riektsina V, Tupasi TE, Wells CD, Zignol M, Cegielski PJ.

Int J Tuberc Lung Dis. 2011 Oct;15(10):1315-22. doi: 10.5588/ijtld.10.0221.

PMID:
22283887
36.

PRL-1 protein promotes ERK1/2 and RhoA protein activation through a non-canonical interaction with the Src homology 3 domain of p115 Rho GTPase-activating protein.

Bai Y, Luo Y, Liu S, Zhang L, Shen K, Dong Y, Walls CD, Quilliam LA, Wells CD, Cao Y, Zhang ZY.

J Biol Chem. 2011 Dec 9;286(49):42316-24. doi: 10.1074/jbc.M111.286302. Epub 2011 Oct 18.

37.

Starch-binding domain-containing protein 1 (Stbd1) and glycogen metabolism: Identification of the Atg8 family interacting motif (AIM) in Stbd1 required for interaction with GABARAPL1.

Jiang S, Wells CD, Roach PJ.

Biochem Biophys Res Commun. 2011 Sep 30;413(3):420-5. doi: 10.1016/j.bbrc.2011.08.106. Epub 2011 Aug 27.

38.

OpenFreezer: a reagent information management software system.

Olhovsky M, Williton K, Dai AY, Pasculescu A, Lee JP, Goudreault M, Wells CD, Park JG, Gingras AC, Linding R, Pawson T, Colwill K.

Nat Methods. 2011 Jul 28;8(8):612-3. doi: 10.1038/nmeth.1658. No abstract available.

PMID:
21799493
39.

Early bactericidal activity of delamanid (OPC-67683) in smear-positive pulmonary tuberculosis patients.

Diacon AH, Dawson R, Hanekom M, Narunsky K, Venter A, Hittel N, Geiter LJ, Wells CD, Paccaly AJ, Donald PR.

Int J Tuberc Lung Dis. 2011 Jul;15(7):949-54. doi: 10.5588/ijtld.10.0616.

PMID:
21682970
40.

6-month versus 36-month isoniazid preventive treatment for tuberculosis in adults with HIV infection in Botswana: a randomised, double-blind, placebo-controlled trial.

Samandari T, Agizew TB, Nyirenda S, Tedla Z, Sibanda T, Shang N, Mosimaneotsile B, Motsamai OI, Bozeman L, Davis MK, Talbot EA, Moeti TL, Moffat HJ, Kilmarx PH, Castro KG, Wells CD.

Lancet. 2011 May 7;377(9777):1588-98. doi: 10.1016/S0140-6736(11)60204-3. Epub 2011 Apr 12.

PMID:
21492926
42.

The adaptor protein AMOT promotes the proliferation of mammary epithelial cells via the prolonged activation of the extracellular signal-regulated kinases.

Ranahan WP, Han Z, Smith-Kinnaman W, Nabinger SC, Heller B, Herbert BS, Chan R, Wells CD.

Cancer Res. 2011 Mar 15;71(6):2203-11. doi: 10.1158/0008-5472.CAN-10-1995. Epub 2011 Feb 1.

43.

Starch binding domain-containing protein 1/genethonin 1 is a novel participant in glycogen metabolism.

Jiang S, Heller B, Tagliabracci VS, Zhai L, Irimia JM, DePaoli-Roach AA, Wells CD, Skurat AV, Roach PJ.

J Biol Chem. 2010 Nov 5;285(45):34960-71. doi: 10.1074/jbc.M110.150839. Epub 2010 Sep 1. Erratum in: J Biol Chem. 2011 Nov 11;286(45):39673.

44.

Multi-drug resistant TB and HIV in Thailand: overlapping, but not independently associated risk factors.

Akksilp S, Wattanaamornkiat W, Kittikraisak W, Nateniyom S, Rienthong S, Sirinak C, Ngamlert K, Mankatittham W, Sattayawuthipong W, Sumnapun S, Yamada N, Monkongdee P, Anuwatnonthakate A, Burapat C, Wells CD, Tappero JW, Varma JK.

Southeast Asian J Trop Med Public Health. 2009 Nov;40(6):1264-78.

PMID:
20578461
45.

Isoniazid-associated hepatitis and antiretroviral drugs during tuberculosis prophylaxis in hiv-infected adults in Botswana.

Tedla Z, Nyirenda S, Peeler C, Agizew T, Sibanda T, Motsamai O, Vernon A, Wells CD, Samandari T.

Am J Respir Crit Care Med. 2010 Jul 15;182(2):278-85. doi: 10.1164/rccm.200911-1783OC. Epub 2010 Apr 8.

PMID:
20378730
46.

Recommendations for the pharmacological management of neuropathic pain: an overview and literature update.

Dworkin RH, O'Connor AB, Audette J, Baron R, Gourlay GK, Haanpää ML, Kent JL, Krane EJ, Lebel AA, Levy RM, Mackey SC, Mayer J, Miaskowski C, Raja SN, Rice AS, Schmader KE, Stacey B, Stanos S, Treede RD, Turk DC, Walco GA, Wells CD.

Mayo Clin Proc. 2010 Mar;85(3 Suppl):S3-14. doi: 10.4065/mcp.2009.0649. Review.

47.

Treatment considerations for patients with neuropathic pain and other medical comorbidities.

Haanpää ML, Gourlay GK, Kent JL, Miaskowski C, Raja SN, Schmader KE, Wells CD.

Mayo Clin Proc. 2010 Mar;85(3 Suppl):S15-25. doi: 10.4065/mcp.2009.0645. Review.

48.

Amot recognizes a juxtanuclear endocytic recycling compartment via a novel lipid binding domain.

Heller B, Adu-Gyamfi E, Smith-Kinnaman W, Babbey C, Vora M, Xue Y, Bittman R, Stahelin RV, Wells CD.

J Biol Chem. 2010 Apr 16;285(16):12308-20. doi: 10.1074/jbc.M109.096230. Epub 2010 Jan 14.

49.

Tuberculosis in asymptomatic HIV-infected adults with abnormal chest radiographs screened for tuberculosis prevention.

Agizew TB, Arwady MA, Yoon JC, Nyirenda S, Mosimaneotsile B, Tedla Z, Motsamai O, Kilmarx PH, Wells CD, Samandari T.

Int J Tuberc Lung Dis. 2010 Jan;14(1):45-51.

PMID:
20003694
50.

Isoniazid tuberculosis preventive therapy in HIV-infected adults accessing antiretroviral therapy: a Botswana Experience, 2004-2006.

Mosimaneotsile B, Mathoma A, Chengeta B, Nyirenda S, Agizew TB, Tedla Z, Motsamai OI, Kilmarx PH, Wells CD, Samandari T.

J Acquir Immune Defic Syndr. 2010 May 1;54(1):71-7. doi: 10.1097/QAI.0b013e3181c3cbf0.

PMID:
19934764

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