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How do health practitioners in a large Australian public hospital identify and respond to reproductive abuse? A qualitative study.

Tarzia L, Wellington M, Marino J, Hegarty K.

Aust N Z J Public Health. 2019 Jul 3. doi: 10.1111/1753-6405.12923. [Epub ahead of print]


Host Carbon Dioxide Concentration Is an Independent Stress for Cryptococcus neoformans That Affects Virulence and Antifungal Susceptibility.

Krysan DJ, Zhai B, Beattie SR, Misel KM, Wellington M, Lin X.

MBio. 2019 Jul 2;10(4). pii: e01410-19. doi: 10.1128/mBio.01410-19.


Effect of supplemental threonine above requirement on growth performance of Salmonella typhimurium challenged pigs fed high fiber diets.

Wellington MO, Agyekum AK, Hamonic K, Htoo JK, Van Kessel AG, Columbus DA.

J Anim Sci. 2019 Jul 1. pii: skz225. doi: 10.1093/jas/skz225. [Epub ahead of print]


"A Huge, Hidden Problem": Australian Health Practitioners' Views and Understandings of Reproductive Coercion.

Tarzia L, Wellington M, Marino J, Hegarty K.

Qual Health Res. 2019 Aug;29(10):1395-1407. doi: 10.1177/1049732318819839. Epub 2018 Dec 25.


Previous antiretroviral drug use compromises standard first-line HIV therapy and is mediated through drug-resistance.

Inzaule SC, Kityo CM, Siwale M, Akanmu AS, Wellington M, de Jager M, Ive P, Mandaliya K, Stevens W, Boender TS, Ondoa P, Sigaloff KCE, Naniche D, Rinke de Wit TF, Hamers RL.

Sci Rep. 2018 Oct 25;8(1):15751. doi: 10.1038/s41598-018-33538-0.


Impact of dietary fiber and immune system stimulation on threonine requirement for protein deposition in growing pigs.

Wellington MO, Htoo JK, Van Kessel AG, Columbus DA.

J Anim Sci. 2018 Dec 3;96(12):5222-5232. doi: 10.1093/jas/sky381.


High-Throughput Screening Identifies Genes Required for Candida albicans Induction of Macrophage Pyroptosis.

O'Meara TR, Duah K, Guo CX, Maxson ME, Gaudet RG, Koselny K, Wellington M, Powers ME, MacAlpine J, O'Meara MJ, Veri AO, Grinstein S, Noble SM, Krysan D, Gray-Owen SD, Cowen LE.

MBio. 2018 Aug 21;9(4). pii: e01581-18. doi: 10.1128/mBio.01581-18.


A Genome-Wide Screen of Deletion Mutants in the Filamentous Saccharomyces cerevisiae Background Identifies Ergosterol as a Direct Trigger of Macrophage Pyroptosis.

Koselny K, Mutlu N, Minard AY, Kumar A, Krysan DJ, Wellington M.

MBio. 2018 Jul 31;9(4). pii: e01204-18. doi: 10.1128/mBio.01204-18.


Suboptimal immune recovery during antiretroviral therapy with sustained HIV suppression in sub-Saharan Africa.

Kroeze S, Ondoa P, Kityo CM, Siwale M, Akanmu S, Wellington M, de Jager M, Ive P, Mandaliya K, Stevens W, Boender TS, de Pundert ME, Sigaloff KCE, Reiss P, Wit FWNM, Rinke de Wit TF, Hamers RL.

AIDS. 2018 May 15;32(8):1043-1051. doi: 10.1097/QAD.0000000000001801.


Systematic Complex Haploinsufficiency-Based Genetic Analysis of Candida albicans Transcription Factors: Tools and Applications to Virulence-Associated Phenotypes.

Glazier VE, Murante T, Koselny K, Murante D, Esqueda M, Wall GA, Wellington M, Hung CY, Kumar A, Krysan DJ.

G3 (Bethesda). 2018 Mar 28;8(4):1299-1314. doi: 10.1534/g3.117.300515.


Temperature cycling during platelet cold storage improves in vivo recovery and survival in healthy volunteers.

Vostal JG, Gelderman MP, Skripchenko A, Xu F, Li Y, Ryan J, Cheng C, Whitley P, Wellington M, Sawyer S, Hanley S, Wagner SJ.

Transfusion. 2018 Jan;58(1):25-33. doi: 10.1111/trf.14392. Epub 2017 Nov 8.


New facets of antifungal therapy.

Chang YL, Yu SJ, Heitman J, Wellington M, Chen YL.

Virulence. 2017 Feb 17;8(2):222-236. doi: 10.1080/21505594.2016.1257457. Epub 2016 Nov 7. Review.


The Celecoxib Derivative AR-12 Has Broad-Spectrum Antifungal Activity In Vitro and Improves the Activity of Fluconazole in a Murine Model of Cryptococcosis.

Koselny K, Green J, DiDone L, Halterman JP, Fothergill AW, Wiederhold NP, Patterson TF, Cushion MT, Rappelye C, Wellington M, Krysan DJ.

Antimicrob Agents Chemother. 2016 Nov 21;60(12):7115-7127. Print 2016 Dec.


Protease Inhibitor Resistance in the First 3 Years of Second-Line Antiretroviral Therapy for HIV-1 in Sub-Saharan Africa.

Boender TS, Hamers RL, Ondoa P, Wellington M, Chimbetete C, Siwale M, Labib Maksimos EE, Balinda SN, Kityo CM, Adeyemo TA, Akanmu AS, Mandaliya K, Botes ME, Stevens W, Rinke de Wit TF, Sigaloff KC.

J Infect Dis. 2016 Sep 15;214(6):873-83. doi: 10.1093/infdis/jiw219. Epub 2016 Jul 11.


Accumulation of HIV-1 drug resistance after continued virological failure on first-line ART in adults and children in sub-Saharan Africa.

Boender TS, Kityo CM, Boerma RS, Hamers RL, Ondoa P, Wellington M, Siwale M, Nankya I, Kaudha E, Akanmu AS, Botes ME, Steegen K, Calis JC, Rinke de Wit TF, Sigaloff KC.

J Antimicrob Chemother. 2016 Oct;71(10):2918-27. doi: 10.1093/jac/dkw218. Epub 2016 Jun 23.


Pre-treatment drug resistance among patients initiating antiretroviral therapy (ART) in Zimbabwe: 2008-2010.

Mungati M, Mhangara M, Gonese E, Mugurungi O, Dzangare J, Ngwende S, Musasa P, Wellington M, Shambira G, Apollo T, Yang C, DeVos J, Sabatier J, Kilmarx P, Chakanyuka-Musanhu C, Tshimanga M.

BMC Res Notes. 2016 Jun 10;9:302. doi: 10.1186/s13104-016-2101-8.


Hearing impairment and deafness among HIV infected children and adolescents in Harare, Zimbabwe.

Chidziva C, Matsekete J, Bandason T, Shamu S, Dzongodza T, Matinhira N, Mujuru HA, Kunzekwenyika C, Wellington M, Luthy R, Prescott C, Ferrand RA.

Cent Afr J Med. 2015 Sep-Dec;61(9-12):56-61.


Pretreatment HIV drug resistance increases regimen switches in sub-Saharan Africa.

Boender TS, Hoenderboom BM, Sigaloff KC, Hamers RL, Wellington M, Shamu T, Siwale M, Labib Maksimos EE, Nankya I, Kityo CM, Adeyemo TA, Akanmu AS, Mandaliya K, Botes ME, Ondoa P, Rinke de Wit TF.

Clin Infect Dis. 2015 Dec 1;61(11):1749-58. doi: 10.1093/cid/civ656. Epub 2015 Aug 3.


Outcomes of Infants Starting Antiretroviral Therapy in Southern Africa, 2004-2012.

Porter M, Davies MA, Mapani MK, Rabie H, Phiri S, Nuttall J, Fairlie L, Technau KG, Stinson K, Wood R, Wellington M, Haas AD, Giddy J, Tanser F, Eley B.

J Acquir Immune Defic Syndr. 2015 Aug 15;69(5):593-601. doi: 10.1097/QAI.0000000000000683.


The Home-Based Occupational Therapy Intervention in the Alzheimer's Disease Multiple Intervention Trial (ADMIT).

Schmid AA, Spangler-Morris C, Beauchamp RC, Wellington MC, Hayden WM, Porterfield HS, Ferguson D, Callahan CM.

Occup Ther Ment Health. 2015 Jan 1;31(1):19-34. Epub 2015 Feb 11.


Uncontrolled hypertension among hypertensive patients on treatment in Lupane District, Zimbabwe, 2012.

Goverwa TP, Masuka N, Tshimanga M, Gombe NT, Takundwa L, Bangure D, Wellington M.

BMC Res Notes. 2014 Oct 8;7:703. doi: 10.1186/1756-0500-7-703.


Performance and logistical challenges of alternative HIV-1 virological monitoring options in a clinical setting of Harare, Zimbabwe.

Ondoa P, Shamu T, Bronze M, Wellington M, Boender TS, Manting C, Steegen K, Luethy R, Rinke de Wit T.

Biomed Res Int. 2014;2014:102598. doi: 10.1155/2014/102598. Epub 2014 Jun 15.


Catching fire: Candida albicans, macrophages, and pyroptosis.

Krysan DJ, Sutterwala FS, Wellington M.

PLoS Pathog. 2014 Jun 26;10(6):e1004139. doi: 10.1371/journal.ppat.1004139. eCollection 2014 Jun. No abstract available.


A tetraploid intermediate precedes aneuploid formation in yeasts exposed to fluconazole.

Harrison BD, Hashemi J, Bibi M, Pulver R, Bavli D, Nahmias Y, Wellington M, Sapiro G, Berman J.

PLoS Biol. 2014 Mar 18;12(3):e1001815. doi: 10.1371/journal.pbio.1001815. eCollection 2014 Mar.


Estrogen receptor antagonists are anti-cryptococcal agents that directly bind EF hand proteins and synergize with fluconazole in vivo.

Butts A, Koselny K, Chabrier-Roselló Y, Semighini CP, Brown JC, Wang X, Annadurai S, DiDone L, Tabroff J, Childers WE Jr, Abou-Gharbia M, Wellington M, Cardenas ME, Madhani HD, Heitman J, Krysan DJ.

MBio. 2014 Feb 11;5(1):e00765-13. doi: 10.1128/mBio.00765-13.


Candida albicans triggers NLRP3-mediated pyroptosis in macrophages.

Wellington M, Koselny K, Sutterwala FS, Krysan DJ.

Eukaryot Cell. 2014 Feb;13(2):329-40. doi: 10.1128/EC.00336-13. Epub 2013 Dec 27.


Factors associated with uptake of voluntary medical male circumcision, Mazowe District, Zimbabwe, 2014.

Rupfutse M, Tshuma C, Tshimanga M, Gombe N, Bangure D, Wellington M.

Pan Afr Med J. 2014 Nov 28;19:337. doi: 10.11604/pamj.2014.19.337.5245. eCollection 2014.


Temporal trends in the characteristics of children at antiretroviral therapy initiation in southern Africa: the IeDEA-SA Collaboration.

Davies MA, Phiri S, Wood R, Wellington M, Cox V, Bolton-Moore C, Timmerman V, Moultrie H, Ndirangu J, Rabie H, Technau K, Giddy J, Maxwell N, Boulle A, Keiser O, Egger M, Eley B; IeDEA Southern Africa Steering Group.

PLoS One. 2013 Dec 9;8(12):e81037. doi: 10.1371/journal.pone.0081037. eCollection 2013.


Candida albicans morphogenesis is not required for macrophage interleukin 1β production.

Wellington M, Koselny K, Krysan DJ.

MBio. 2012 Dec 26;4(1):e00433-12. doi: 10.1128/mBio.00433-12.


A repurposing approach identifies off-patent drugs with fungicidal cryptococcal activity, a common structural chemotype, and pharmacological properties relevant to the treatment of cryptococcosis.

Butts A, DiDone L, Koselny K, Baxter BK, Chabrier-Rosello Y, Wellington M, Krysan DJ.

Eukaryot Cell. 2013 Feb;12(2):278-87. doi: 10.1128/EC.00314-12. Epub 2012 Dec 14.


Tuberculosis and the risk of opportunistic infections and cancers in HIV-infected patients starting ART in Southern Africa.

Fenner L, Reid SE, Fox MP, Garone D, Wellington M, Prozesky H, Zwahlen M, Schomaker M, Wandeler G, Kancheya N, Boulle A, Wood R, Henostroza G, Egger M; IeDEA Southern Africa.

Trop Med Int Health. 2013 Feb;18(2):194-8. doi: 10.1111/tmi.12026. Epub 2012 Nov 30.


Variability of growth in children starting antiretroviral treatment in southern Africa.

Gsponer T, Weigel R, Davies MA, Bolton C, Moultrie H, Vaz P, Rabie H, Technau K, Ndirangu J, Eley B, Garone D, Wellington M, Giddy J, Ehmer J, Egger M, Keiser O; IeDEA Southern Africa.

Pediatrics. 2012 Oct;130(4):e966-77. doi: 10.1542/peds.2011-3020. Epub 2012 Sep 17.


Early warning indicators for population-based monitoring of HIV drug resistance in 6 African countries.

Sigaloff KC, Hamers RL, Menke J, Labib M, Siwale M, Ive P, Botes ME, Kityo C, Mandaliya K, Wellington M, Osibogun A, Geskus RB, Stevens WS, van Vugt M, Rinke de Wit TF; PharmAccess African Studies to Evaluate Resistance.

Clin Infect Dis. 2012 May;54 Suppl 4:S294-9. doi: 10.1093/cid/cir1015.


Building capacity for the assessment of HIV drug resistance: experiences from the PharmAccess African Studies to Evaluate Resistance network.

Hamers RL, Straatsma E, Kityo C, Wallis CL, Stevens WS, Sigaloff KC, Siwale M, Conradie F, Botes ME, Mandaliya K, Wellington M, Osibogun A, van Vugt M, Rinke de Wit TF; PharmAccess African Studies to Evaluate Resistance.

Clin Infect Dis. 2012 May;54 Suppl 4:S261-5. doi: 10.1093/cid/cir995.


The Spx regulator modulates stress responses and virulence in Enterococcus faecalis.

Kajfasz JK, Mendoza JE, Gaca AO, Miller JH, Koselny KA, Giambiagi-Demarval M, Wellington M, Abranches J, Lemos JA.

Infect Immun. 2012 Jul;80(7):2265-75. doi: 10.1128/IAI.00026-12. Epub 2012 Apr 16.


Patterns of HIV-1 drug resistance after first-line antiretroviral therapy (ART) failure in 6 sub-Saharan African countries: implications for second-line ART strategies.

Hamers RL, Sigaloff KC, Wensing AM, Wallis CL, Kityo C, Siwale M, Mandaliya K, Ive P, Botes ME, Wellington M, Osibogun A, Stevens WS, Rinke de Wit TF, Schuurman R; PharmAccess African Studies to Evaluate Resistance (PASER).

Clin Infect Dis. 2012 Jun;54(11):1660-9. doi: 10.1093/cid/cis254. Epub 2012 Apr 3.


Second-line antiretroviral treatment successfully resuppresses drug-resistant HIV-1 after first-line failure: prospective cohort in Sub-Saharan Africa.

Sigaloff KC, Hamers RL, Wallis CL, Kityo C, Siwale M, Ive P, Botes ME, Mandaliya K, Wellington M, Osibogun A, Stevens WS, van Vugt M, Rinke de Wit TF; PharmAccess African Studies to Evaluate Resistance (PASER).

J Infect Dis. 2012 Jun;205(11):1739-44. doi: 10.1093/infdis/jis261. Epub 2012 Mar 23.


TGF-β1 enhances contractility in engineered skeletal muscle.

Weist MR, Wellington MS, Bermudez JE, Kostrominova TY, Mendias CL, Arruda EM, Larkin LM.

J Tissue Eng Regen Med. 2013 Jul;7(7):562-71. doi: 10.1002/term.551. Epub 2012 Feb 27.


Effect of pretreatment HIV-1 drug resistance on immunological, virological, and drug-resistance outcomes of first-line antiretroviral treatment in sub-Saharan Africa: a multicentre cohort study.

Hamers RL, Schuurman R, Sigaloff KC, Wallis CL, Kityo C, Siwale M, Mandaliya K, Ive P, Botes ME, Wellington M, Osibogun A, Wit FW, van Vugt M, Stevens WS, de Wit TF; PharmAccess African Studies to Evaluate Resistance (PASER) Investigators.

Lancet Infect Dis. 2012 Apr;12(4):307-17. doi: 10.1016/S1473-3099(11)70255-9. Epub 2011 Oct 27.


HIV-1 drug resistance in antiretroviral-naive individuals in sub-Saharan Africa after rollout of antiretroviral therapy: a multicentre observational study.

Hamers RL, Wallis CL, Kityo C, Siwale M, Mandaliya K, Conradie F, Botes ME, Wellington M, Osibogun A, Sigaloff KC, Nankya I, Schuurman R, Wit FW, Stevens WS, van Vugt M, de Wit TF; PharmAccess African Studies to Evaluate Resistance (PASER).

Lancet Infect Dis. 2011 Oct;11(10):750-9. doi: 10.1016/S1473-3099(11)70149-9. Epub 2011 Jul 27.


Unnecessary antiretroviral treatment switches and accumulation of HIV resistance mutations; two arguments for viral load monitoring in Africa.

Sigaloff KC, Hamers RL, Wallis CL, Kityo C, Siwale M, Ive P, Botes ME, Mandaliya K, Wellington M, Osibogun A, Stevens WS, van Vugt M, de Wit TF; PharmAccess African Studies to Evaluate Resistance (PASER).

J Acquir Immune Defic Syndr. 2011 Sep 1;58(1):23-31. doi: 10.1097/QAI.0b013e318227fc34.


Imaging morphogenesis of Candida albicans during infection in a live animal.

Mitra S, Dolan K, Foster TH, Wellington M.

J Biomed Opt. 2010 Jan-Feb;15(1):010504. doi: 10.1117/1.3290243.


Nitrite reductase NirS is required for type III secretion system expression and virulence in the human monocyte cell line THP-1 by Pseudomonas aeruginosa.

Van Alst NE, Wellington M, Clark VL, Haidaris CG, Iglewski BH.

Infect Immun. 2009 Oct;77(10):4446-54. doi: 10.1128/IAI.00822-09. Epub 2009 Aug 3.


Antifungal activity of tamoxifen: in vitro and in vivo activities and mechanistic characterization.

Dolan K, Montgomery S, Buchheit B, Didone L, Wellington M, Krysan DJ.

Antimicrob Agents Chemother. 2009 Aug;53(8):3337-46. doi: 10.1128/AAC.01564-08. Epub 2009 Jun 1.


Live Candida albicans suppresses production of reactive oxygen species in phagocytes.

Wellington M, Dolan K, Krysan DJ.

Infect Immun. 2009 Jan;77(1):405-13. doi: 10.1128/IAI.00860-08. Epub 2008 Nov 3.


Monocyte responses to Candida albicans are enhanced by antibody in cooperation with antibody-independent pathogen recognition.

Wellington M, Dolan K, Haidaris CG.

FEMS Immunol Med Microbiol. 2007 Oct;51(1):70-83. Epub 2007 Jul 4.


5-fluoro-orotic acid induces chromosome alterations in genetically manipulated strains of Candida albicans.

Wellington M, Kabir MA, Rustchenko E.

Mycologia. 2006 May-Jun;98(3):393-8.


Consultation with the specialist: genital warts.

Wellington MA, Bonnez W.

Pediatr Rev. 2005 Dec;26(12):467-71. No abstract available.


Chronic cough in primary health care attendees, Harare, Zimbabwe: diagnosis and impact of HIV infection.

Munyati SS, Dhoba T, Makanza ED, Mungofa S, Wellington M, Mutsvangwa J, Gwanzura L, Hakim J, Nyakabau M, Mason PR, Robertson V, Rusakaniko S, Butterworth AE, Corbett EL.

Clin Infect Dis. 2005 Jun 15;40(12):1818-27. Epub 2005 May 12.


5-Fluoro-orotic acid induces chromosome alterations in Candida albicans.

Wellington M, Rustchenko E.

Yeast. 2005 Jan 15;22(1):57-70.

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