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Items: 1 to 50 of 150

1.

An Automated Kinematic Measurement System for Sagittal Plane Murine Head Impacts.

McInnes KA, Abebe Z, Whyte T, Bashir A, Barron C, Wellington C, Cripton PA.

J Biomech Eng. 2020 Feb 3. doi: 10.1115/1.4046202. [Epub ahead of print]

PMID:
32006027
2.

"Take Charge, Get Cured": Pilot testing a targeted mHealth treatment decision support tool for methadone patients with hepatitis C virus for acceptability and promise of efficacy.

Jessop AB, Bass SB, Brajuha J, Alhajji M, Burke M, Gashat MT, Wellington C, Ventriglia N, Coleman J, D'Avanzo P.

J Subst Abuse Treat. 2020 Feb;109:23-33. doi: 10.1016/j.jsat.2019.11.001. Epub 2019 Nov 6.

PMID:
31856947
3.

Increased severity of the CHIMERA model induces acute vascular injury, sub-acute deficits in memory recall, and chronic white matter gliosis.

Bashir A, Abebe ZA, McInnes KA, Button EB, Tatarnikov I, Cheng WH, Haber M, Wilkinson A, Barron C, Diaz-Arrastia R, Stukas S, Cripton PA, Wellington CL.

Exp Neurol. 2020 Feb;324:113116. doi: 10.1016/j.expneurol.2019.113116. Epub 2019 Nov 15.

PMID:
31734317
4.

Technique and preliminary findings for in vivo quantification of brain motion during injurious head impacts.

Whyte T, Liu J, Chung V, McErlane SA, Abebe ZA, McInnes KA, Wellington CL, Cripton PA.

J Biomech. 2019 Oct 11;95:109279. doi: 10.1016/j.jbiomech.2019.07.023. Epub 2019 Jul 27.

PMID:
31443944
5.

Cerebral Microvascular Injury: A Potentially Treatable Endophenotype of Traumatic Brain Injury-Induced Neurodegeneration.

Sandsmark DK, Bashir A, Wellington CL, Diaz-Arrastia R.

Neuron. 2019 Aug 7;103(3):367-379. doi: 10.1016/j.neuron.2019.06.002. Review.

PMID:
31394062
6.

Medical Mistrust and PrEP Perceptions Among Transgender Women: A Cluster Analysis.

D'Avanzo PA, Bass SB, Brajuha J, Gutierrez-Mock L, Ventriglia N, Wellington C, Sevelius J.

Behav Med. 2019 Apr-Jun;45(2):143-152. doi: 10.1080/08964289.2019.1585325.

7.

A Rationally Designed Humanized Antibody Selective for Amyloid Beta Oligomers in Alzheimer's Disease.

Gibbs E, Silverman JM, Zhao B, Peng X, Wang J, Wellington CL, Mackenzie IR, Plotkin SS, Kaplan JM, Cashman NR.

Sci Rep. 2019 Jul 8;9(1):9870. doi: 10.1038/s41598-019-46306-5.

8.

Characterisation of serum total tau following paediatric traumatic brain injury: a case-control study.

Stukas S, Higgins V, Frndova H, Gill J, Hubara E, Guerguerian AM, Boutis K, Beauchamp M, Farrell C, Babl FE, Delzoppo C, Greenham M, Wilkinson AA, Crichton A, Anderson V, Adeli K, Hutchison J, Wellington C; Serum Biomarkers and Quality of Life in Children with Traumatic Brain Injury investigators; National Biobank and Database for Patients with Traumatic Brain Injury investigators; Canadian Critical Care Translation Biology Group, and the Canadian Traumatic Brain Injury Research Consortium.

Lancet Child Adolesc Health. 2019 Aug;3(8):558-567. doi: 10.1016/S2352-4642(19)30194-4. Epub 2019 Jun 21.

PMID:
31231066
9.

ApoA-I deficiency increases cortical amyloid deposition, cerebral amyloid angiopathy, cortical and hippocampal astrogliosis, and amyloid-associated astrocyte reactivity in APP/PS1 mice.

Button EB, Boyce GK, Wilkinson A, Stukas S, Hayat A, Fan J, Wadsworth BJ, Robert J, Martens KM, Wellington CL.

Alzheimers Res Ther. 2019 May 13;11(1):44. doi: 10.1186/s13195-019-0497-9.

10.

White matter hyperintensities in vascular contributions to cognitive impairment and dementia (VCID): Knowledge gaps and opportunities.

Alber J, Alladi S, Bae HJ, Barton DA, Beckett LA, Bell JM, Berman SE, Biessels GJ, Black SE, Bos I, Bowman GL, Brai E, Brickman AM, Callahan BL, Corriveau RA, Fossati S, Gottesman RF, Gustafson DR, Hachinski V, Hayden KM, Helman AM, Hughes TM, Isaacs JD, Jefferson AL, Johnson SC, Kapasi A, Kern S, Kwon JC, Kukolja J, Lee A, Lockhart SN, Murray A, Osborn KE, Power MC, Price BR, Rhodius-Meester HFM, Rondeau JA, Rosen AC, Rosene DL, Schneider JA, Scholtzova H, Shaaban CE, Silva NCBS, Snyder HM, Swardfager W, Troen AM, van Veluw SJ, Vemuri P, Wallin A, Wellington C, Wilcock DM, Xie SX, Hainsworth AH.

Alzheimers Dement (N Y). 2019 Apr 9;5:107-117. doi: 10.1016/j.trci.2019.02.001. eCollection 2019. Review.

11.

HDL from an Alzheimer's disease perspective.

Button EB, Robert J, Caffrey TM, Fan J, Zhao W, Wellington CL.

Curr Opin Lipidol. 2019 Jun;30(3):224-234. doi: 10.1097/MOL.0000000000000604.

12.

Repetitive closed-head impact model of engineered rotational acceleration (CHIMERA) injury in rats increases impulsivity, decreases dopaminergic innervation in the olfactory tubercle and generates white matter inflammation, tau phosphorylation and degeneration.

Vonder Haar C, Martens KM, Bashir A, McInnes KA, Cheng WH, Cheung H, Stukas S, Barron C, Ladner T, Welch KA, Cripton PA, Winstanley CA, Wellington CL.

Exp Neurol. 2019 Jul;317:87-99. doi: 10.1016/j.expneurol.2019.02.012. Epub 2019 Feb 26.

PMID:
30822421
13.

Primum non nocere: a call for balance when reporting on CTE.

Stewart W, Allinson K, Al-Sarraj S, Bachmeier C, Barlow K, Belli A, Burns MP, Carson A, Crawford F, Dams-O'Connor K, Diaz-Arrastia R, Dixon CE, Edlow BL, Ferguson S, Fischl B, Folkerth RD, Gentleman S, Giza CC, Grady MS, Helmy A, Herceg M, Holton JL, Howell D, Hutchinson PJ, Iacono D, Iglesias JE, Ikonomovic MD, Johnson VE, Keene CD, Kofler JK, Koliatsos VE, Lee EB, Levin H, Lifshitz J, Ling H, Loane DJ, Love S, Maas AI, Marklund N, Master CL, McElvenny DM, Meaney DF, Menon DK, Montine TJ, Mouzon B, Mufson EJ, Ojo JO, Prins M, Revesz T, Ritchie CW, Smith C, Sylvester R, Tang CY, Trojanowski JQ, Urankar K, Vink R, Wellington C, Wilde EA, Wilson L, Yeates K, Smith DH.

Lancet Neurol. 2019 Mar;18(3):231-233. doi: 10.1016/S1474-4422(19)30020-1. Epub 2019 Feb 12. No abstract available. Erratum in: Lancet Neurol. 2019 Apr;18(4):e3.

14.

Vasoprotective Functions of High-Density Lipoproteins Relevant to Alzheimer's Disease Are Partially Conserved in Apolipoprotein B-Depleted Plasma.

Button EB, Gilmour M, Cheema HK, Martin EM, Agbay A, Robert J, Wellington CL.

Int J Mol Sci. 2019 Jan 22;20(3). pii: E462. doi: 10.3390/ijms20030462.

15.

Vascular dysfunction-The disregarded partner of Alzheimer's disease.

Sweeney MD, Montagne A, Sagare AP, Nation DA, Schneider LS, Chui HC, Harrington MG, Pa J, Law M, Wang DJJ, Jacobs RE, Doubal FN, Ramirez J, Black SE, Nedergaard M, Benveniste H, Dichgans M, Iadecola C, Love S, Bath PM, Markus HS, Salman RA, Allan SM, Quinn TJ, Kalaria RN, Werring DJ, Carare RO, Touyz RM, Williams SCR, Moskowitz MA, Katusic ZS, Lutz SE, Lazarov O, Minshall RD, Rehman J, Davis TP, Wellington CL, González HM, Yuan C, Lockhart SN, Hughes TM, Chen CLH, Sachdev P, O'Brien JT, Skoog I, Pantoni L, Gustafson DR, Biessels GJ, Wallin A, Smith EE, Mok V, Wong A, Passmore P, Barkof F, Muller M, Breteler MMB, Román GC, Hamel E, Seshadri S, Gottesman RF, van Buchem MA, Arvanitakis Z, Schneider JA, Drewes LR, Hachinski V, Finch CE, Toga AW, Wardlaw JM, Zlokovic BV.

Alzheimers Dement. 2019 Jan;15(1):158-167. doi: 10.1016/j.jalz.2018.07.222.

16.

CHIMERA repetitive mild traumatic brain injury induces chronic behavioural and neuropathological phenotypes in wild-type and APP/PS1 mice.

Cheng WH, Martens KM, Bashir A, Cheung H, Stukas S, Gibbs E, Namjoshi DR, Button EB, Wilkinson A, Barron CJ, Cashman NR, Cripton PA, Wellington CL.

Alzheimers Res Ther. 2019 Jan 12;11(1):6. doi: 10.1186/s13195-018-0461-0.

17.

Military-related risk factors for dementia.

Snyder HM, Carare RO, DeKosky ST, de Leon MJ, Dykxhoorn D, Gan L, Gardner R, Hinds SR 2nd, Jaffee M, Lamb BT, Landau S, Manley G, McKee A, Perl D, Schneider JA, Weiner M, Wellington C, Yaffe K, Bain L, Pacifico AM, Carrillo MC.

Alzheimers Dement. 2018 Dec;14(12):1651-1662. doi: 10.1016/j.jalz.2018.08.011. Epub 2018 Nov 8. Review.

18.

An End-to-end System for Automatic Characterization of Iba1 Immunopositive Microglia in Whole Slide Imaging.

Kyriazis AD, Noroozizadeh S, Refaee A, Choi W, Chu LT, Bashir A, Cheng WH, Zhao R, Namjoshi DR, Salcudean SE, Wellington CL, Nir G.

Neuroinformatics. 2019 Jul;17(3):373-389. doi: 10.1007/s12021-018-9405-x.

PMID:
30406865
19.

Bright Spots, physical activity investments that work: Parkrun; a global initiative striving for healthier and happier communities.

Reece LJ, Quirk H, Wellington C, Haake SJ, Wilson F.

Br J Sports Med. 2019 Mar;53(6):326-327. doi: 10.1136/bjsports-2018-100041. Epub 2018 Sep 27. No abstract available.

PMID:
30262451
20.

The Canadian Traumatic Brain Injury Research Consortium: Epitomizing Collaborative Research in Canada.

Hutchison JS, Emery C, Gagnon I, Léger C, Riopelle R, Wellington C, Wilson E, Turgeon AF.

J Neurotrauma. 2018 Aug 15;35(16):1858-1863. doi: 10.1089/neu.2018.5871.

PMID:
30074867
21.

modCHIMERA: a novel murine closed-head model of moderate traumatic brain injury.

Sauerbeck AD, Fanizzi C, Kim JH, Gangolli M, Bayly PV, Wellington CL, Brody DL, Kummer TT.

Sci Rep. 2018 May 16;8(1):7677. doi: 10.1038/s41598-018-25737-6.

22.

A Rational Structured Epitope Defines a Distinct Subclass of Toxic Amyloid-beta Oligomers.

Silverman JM, Gibbs E, Peng X, Martens KM, Balducci C, Wang J, Yousefi M, Cowan CM, Lamour G, Louadi S, Ban Y, Robert J, Stukas S, Forloni G, Hsiung GR, Plotkin SS, Wellington CL, Cashman NR.

ACS Chem Neurosci. 2018 Jul 18;9(7):1591-1606. doi: 10.1021/acschemneuro.7b00469. Epub 2018 Apr 16.

PMID:
29614860
23.

Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway.

Fan J, Zhao RQ, Parro C, Zhao W, Chou HY, Robert J, Deeb TZ, Raynoschek C, Barichievy S, Engkvist O, Maresca M, Hicks R, Meuller J, Moss SJ, Brandon NJ, Wood MW, Kulic I, Wellington CL.

J Lipid Res. 2018 May;59(5):830-842. doi: 10.1194/jlr.M081851. Epub 2018 Mar 21.

24.

Age at injury and genotype modify acute inflammatory and neurofilament-light responses to mild CHIMERA traumatic brain injury in wild-type and APP/PS1 mice.

Cheng WH, Stukas S, Martens KM, Namjoshi DR, Button EB, Wilkinson A, Bashir A, Robert J, Cripton PA, Wellington CL.

Exp Neurol. 2018 Mar;301(Pt A):26-38. doi: 10.1016/j.expneurol.2017.12.007. Epub 2017 Dec 18.

PMID:
29269117
25.

Clearance of beta-amyloid is facilitated by apolipoprotein E and circulating high-density lipoproteins in bioengineered human vessels.

Robert J, Button EB, Yuen B, Gilmour M, Kang K, Bahrabadi A, Stukas S, Zhao W, Kulic I, Wellington CL.

Elife. 2017 Oct 10;6. pii: e29595. doi: 10.7554/eLife.29595.

26.

Defining an Analytic Framework to Evaluate Quantitative MRI Markers of Traumatic Axonal Injury: Preliminary Results in a Mouse Closed Head Injury Model.

Haber M, Hutchinson EB, Sadeghi N, Cheng WH, Namjoshi D, Cripton P, Irfanoglu MO, Wellington C, Diaz-Arrastia R, Pierpaoli C.

eNeuro. 2017 Sep 13;4(5). pii: ENEURO.0164-17.2017. doi: 10.1523/ENEURO.0164-17.2017. eCollection 2017 Sep-Oct.

27.

High-density lipoproteins suppress Aβ-induced PBMC adhesion to human endothelial cells in bioengineered vessels and in monoculture.

Robert J, Button EB, Stukas S, Boyce GK, Gibbs E, Cowan CM, Gilmour M, Cheng WH, Soo SK, Yuen B, Bahrabadi A, Kang K, Kulic I, Francis G, Cashman N, Wellington CL.

Mol Neurodegener. 2017 Aug 22;12(1):60. doi: 10.1186/s13024-017-0201-0.

28.

The pleiotropic vasoprotective functions of high density lipoproteins (HDL).

Boyce G, Button E, Soo S, Wellington C.

J Biomed Res. 2017 May 26. doi: 10.7555/JBR.31.20160103. [Epub ahead of print]

29.

Frontal Traumatic Brain Injury Increases Impulsive Decision Making in Rats: A Potential Role for the Inflammatory Cytokine Interleukin-12.

Vonder Haar C, Martens KM, Riparip LK, Rosi S, Wellington CL, Winstanley CA.

J Neurotrauma. 2017 Oct 1;34(19):2790-2800. doi: 10.1089/neu.2016.4813. Epub 2017 May 24.

30.

Defining the biomechanical and biological threshold of murine mild traumatic brain injury using CHIMERA (Closed Head Impact Model of Engineered Rotational Acceleration).

Namjoshi DR, Cheng WH, Bashir A, Wilkinson A, Stukas S, Martens KM, Whyte T, Abebe ZA, McInnes KA, Cripton PA, Wellington CL.

Exp Neurol. 2017 Jun;292:80-91. doi: 10.1016/j.expneurol.2017.03.003. Epub 2017 Mar 6.

31.

The experience of weight management in normal weight adults.

Hernandez CA, Hernandez DA, Wellington CM, Kidd A.

Appl Nurs Res. 2016 Nov;32:289-295. doi: 10.1016/j.apnr.2016.08.009. Epub 2016 Aug 30.

PMID:
27969045
32.

Identification of a Chrysanthemic Ester as an Apolipoprotein E Inducer in Astrocytes.

Fan J, Zareyan S, Zhao W, Shimizu Y, Pfeifer TA, Tak JH, Isman MB, Van den Hoven B, Duggan ME, Wood MW, Wellington CL, Kulic I.

PLoS One. 2016 Sep 6;11(9):e0162384. doi: 10.1371/journal.pone.0162384. eCollection 2016.

33.

Relation between plasma and brain lipids.

Wellington CL, Frikke-Schmidt R.

Curr Opin Lipidol. 2016 Jun;27(3):225-32. doi: 10.1097/MOL.0000000000000291. Review.

PMID:
27149391
34.

Distinct roles for metalloproteinases during traumatic brain injury.

Zhang S, Kojic L, Tsang M, Grewal P, Liu J, Namjoshi D, Wellington CL, Tetzlaff W, Cynader MS, Jia W.

Neurochem Int. 2016 Jun;96:46-55. doi: 10.1016/j.neuint.2016.02.013. Epub 2016 Mar 3.

PMID:
26939762
35.

Chronic Exposure to Androgenic-Anabolic Steroids Exacerbates Axonal Injury and Microgliosis in the CHIMERA Mouse Model of Repetitive Concussion.

Namjoshi DR, Cheng WH, Carr M, Martens KM, Zareyan S, Wilkinson A, McInnes KA, Cripton PA, Wellington CL.

PLoS One. 2016 Jan 19;11(1):e0146540. doi: 10.1371/journal.pone.0146540. eCollection 2016.

36.

Reconstituted high-density lipoproteins acutely reduce soluble brain Aβ levels in symptomatic APP/PS1 mice.

Robert J, Stukas S, Button E, Cheng WH, Lee M, Fan J, Wilkinson A, Kulic I, Wright SD, Wellington CL.

Biochim Biophys Acta. 2016 May;1862(5):1027-36. doi: 10.1016/j.bbadis.2015.10.005. Epub 2015 Oct 9.

37.

Attentional bias and treatment adherence in substitute-prescribed opiate users.

Charles M, Wellington CE, Mokrysz C, Freeman TP, O'Ryan D, Curran HV.

Addict Behav. 2015 Jul;46:100-5. doi: 10.1016/j.addbeh.2015.03.017. Epub 2015 Mar 24.

PMID:
25838001
38.

Vascular contributions to cognitive impairment and dementia including Alzheimer's disease.

Snyder HM, Corriveau RA, Craft S, Faber JE, Greenberg SM, Knopman D, Lamb BT, Montine TJ, Nedergaard M, Schaffer CB, Schneider JA, Wellington C, Wilcock DM, Zipfel GJ, Zlokovic B, Bain LJ, Bosetti F, Galis ZS, Koroshetz W, Carrillo MC.

Alzheimers Dement. 2015 Jun;11(6):710-7. doi: 10.1016/j.jalz.2014.10.008. Epub 2014 Dec 12. Review.

39.

Merging pathology with biomechanics using CHIMERA (Closed-Head Impact Model of Engineered Rotational Acceleration): a novel, surgery-free model of traumatic brain injury.

Namjoshi DR, Cheng WH, McInnes KA, Martens KM, Carr M, Wilkinson A, Fan J, Robert J, Hayat A, Cripton PA, Wellington CL.

Mol Neurodegener. 2014 Dec 1;9:55. doi: 10.1186/1750-1326-9-55.

40.

Intravenously injected human apolipoprotein A-I rapidly enters the central nervous system via the choroid plexus.

Stukas S, Robert J, Lee M, Kulic I, Carr M, Tourigny K, Fan J, Namjoshi D, Lemke K, DeValle N, Chan J, Wilson T, Wilkinson A, Chapanian R, Kizhakkedathu JN, Cirrito JR, Oda MN, Wellington CL.

J Am Heart Assoc. 2014 Nov 12;3(6):e001156. doi: 10.1161/JAHA.114.001156.

41.

Emotional reactions to pain predict psychological distress in adult patients with Sickle Cell Disease (SCD).

Edwards CL, Killough A, Wood M, Doyle T, Feliu M, Barker CS, Uppal P, DeCastro L, Wellington C, Whitfield KE, O'Garo KG, Morgan K, Edwards Alesii LY, Byrd GS, McCabe M, Goli V, Keys A, Hill L, Collins-McNeil J, Trambadia J, Guinyard D, Muhammad M, McDonald P, Schmechel DE, Robinson E.

Int J Psychiatry Med. 2014;47(1):1-16.

42.

LCAT deficiency does not impair amyloid metabolism in APP/PS1 mice.

Stukas S, Freeman L, Lee M, Wilkinson A, Ossoli A, Vaisman B, Demosky S, Chan J, Hirsch-Reinshagen V, Remaley AT, Wellington CL.

J Lipid Res. 2014 Aug;55(8):1721-9. doi: 10.1194/jlr.M049940. Epub 2014 Jun 20.

43.

ApoE secretion modulating bromotyrosine derivative from the Australian marine sponge Callyspongia sp.

Tian LW, Feng Y, Shimizu Y, Pfeifer TA, Wellington C, Hooper JN, Quinn RJ.

Bioorg Med Chem Lett. 2014 Aug 1;24(15):3537-40. doi: 10.1016/j.bmcl.2014.05.054. Epub 2014 Jun 2.

44.

HDL and cholesterol handling in the brain.

Vitali C, Wellington CL, Calabresi L.

Cardiovasc Res. 2014 Aug 1;103(3):405-13. doi: 10.1093/cvr/cvu148. Epub 2014 Jun 6. Review.

PMID:
24907980
45.

Aplysinellamides A-C, bromotyrosine-derived metabolites from an Australian Aplysinella sp. marine sponge.

Tian LW, Feng Y, Shimizu Y, Pfeifer T, Wellington C, Hooper JN, Quinn RJ.

J Nat Prod. 2014 May 23;77(5):1210-4. doi: 10.1021/np500119e. Epub 2014 Apr 23.

PMID:
24758268
46.

Epithelial inflammation resulting from an inherited loss-of-function mutation in EGFR.

Campbell P, Morton PE, Takeichi T, Salam A, Roberts N, Proudfoot LE, Mellerio JE, Aminu K, Wellington C, Patil SN, Akiyama M, Liu L, McMillan JR, Aristodemou S, Ishida-Yamamoto A, Abdul-Wahab A, Petrof G, Fong K, Harnchoowong S, Stone KL, Harper JI, Irwin McLean WH, Simpson MA, Parsons M, McGrath JA.

J Invest Dermatol. 2014 Oct;134(10):2570-2578. doi: 10.1038/jid.2014.164. Epub 2014 Apr 1.

47.

High-density lipoproteins and cerebrovascular integrity in Alzheimer's disease.

Stukas S, Robert J, Wellington CL.

Cell Metab. 2014 Apr 1;19(4):574-91. doi: 10.1016/j.cmet.2014.01.003. Epub 2014 Feb 6. Review.

48.

Towards clinical management of traumatic brain injury: a review of models and mechanisms from a biomechanical perspective.

Namjoshi DR, Good C, Cheng WH, Panenka W, Richards D, Cripton PA, Wellington CL.

Dis Model Mech. 2013 Nov;6(6):1325-38. doi: 10.1242/dmm.011320. Epub 2013 Sep 12. Review.

49.

Classification of fish samples via an integrated proteomics and bioinformatics approach.

Bellgard M, Taplin R, Chapman B, Livk A, Wellington C, Hunter A, Lipscombe R.

Proteomics. 2013 Nov;13(21):3124-30. doi: 10.1002/pmic.201200426.

PMID:
24038899
50.

Hormonal modulators of glial ABCA1 and apoE levels.

Fan J, Shimizu Y, Chan J, Wilkinson A, Ito A, Tontonoz P, Dullaghan E, Galea LA, Pfeifer T, Wellington CL.

J Lipid Res. 2013 Nov;54(11):3139-50. doi: 10.1194/jlr.M042473. Epub 2013 Sep 2.

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