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Items: 1 to 50 of 1315

1.

Synergistic growth inhibition mediated by dual PI3K/mTOR pathway targeting and genetic or direct pharmacological AKT inhibition in human glioblastoma models.

Von Achenbach C, Weller M, Kaulich K, Gramatzki D, Zacher A, Fabbro D, Reifenberger G, Szabó E.

J Neurochem. 2019 Oct 16. doi: 10.1111/jnc.14899. [Epub ahead of print]

PMID:
31618458
2.

Lymphatic outflow of cerebrospinal fluid is reduced in glioma.

Ma Q, Schlegel F, Bachmann SB, Schneider H, Decker Y, Rudin M, Weller M, Proulx ST, Detmar M.

Sci Rep. 2019 Oct 15;9(1):14815. doi: 10.1038/s41598-019-51373-9.

3.

Romiplostim for temozolomide-induced thrombocytopenia in glioblastoma: The PLATUM trial.

Le Rhun E, Devos P, Houillier C, Cartalat S, Chinot O, Di Stefano AL, Lepage C, Reyns N, Dubois F, Weller M.

Neurology. 2019 Oct 4. pii: 10.1212/WNL.0000000000008440. doi: 10.1212/WNL.0000000000008440. [Epub ahead of print]

PMID:
31586022
4.

Underweight and weight loss are predictors of poor outcome in patients with brain metastasis.

Lareida A, Terziev R, Grossenbacher B, Andratschke N, Roth P, Rohrmann S, Stahel R, Guckenberger M, Le Rhun E, Weller M, Wolpert F.

J Neurooncol. 2019 Sep 30. doi: 10.1007/s11060-019-03300-1. [Epub ahead of print]

PMID:
31571112
5.

Challenges in the diagnoses and treatment of CNS tumors.

Weller M.

Neurooncol Pract. 2019 Sep;6(5):329. doi: 10.1093/nop/npz044. Epub 2019 Sep 20. No abstract available.

PMID:
31555446
6.

Molecular targeted therapy of glioblastoma.

Le Rhun E, Preusser M, Roth P, Reardon DA, van den Bent M, Wen P, Reifenberger G, Weller M.

Cancer Treat Rev. 2019 Sep 11;80:101896. doi: 10.1016/j.ctrv.2019.101896. [Epub ahead of print] Review.

PMID:
31541850
7.

Therapeutic targeting of TGF-β ligands in glioblastoma using novel antisense oligonucleotides reduces the growth of experimental gliomas.

Papachristodoulou A, Silginer M, Weller M, Schneider H, Hasenbach K, Janicot M, Roth P.

Clin Cancer Res. 2019 Sep 17. pii: clincanres.3024.2017. doi: 10.1158/1078-0432.CCR-17-3024. [Epub ahead of print]

PMID:
31530630
8.

Predisposing and precipitating factors for delirium in neurology: a prospective cohort study of 1487 patients.

Zipser CM, Deuel J, Ernst J, Schubert M, Weller M, von Känel R, Boettger S.

J Neurol. 2019 Sep 13. doi: 10.1007/s00415-019-09533-4. [Epub ahead of print]

PMID:
31520105
9.

EANO Guideline on the Diagnosis and Treatment of Vestibular Schwannoma.

Goldbrunner R, Weller M, Regis J, Lund-Johansen M, Stavrinou P, Reuss D, Evans DG, Lefranc F, Sallabanda K, Falini A, Axon P, Sterkers O, Fariselli L, Wick W, Tonn JC.

Neuro Oncol. 2019 Aug 28. pii: noz153. doi: 10.1093/neuonc/noz153. [Epub ahead of print]

PMID:
31504802
10.

Risk factors for the development of epilepsy in patients with brain metastasis.

Wolpert F, Lareida A, Terziev R, Grossenbacher B, Neidert MC, Roth P, Poryazova R, Imbach L, Le Rhun E, Weller M.

Neuro Oncol. 2019 Sep 10. pii: noz172. doi: 10.1093/neuonc/noz172. [Epub ahead of print]

PMID:
31498867
11.

High-throughput proteomic analysis of FFPE tissue samples facilitates tumor stratification.

Zhu Y, Weiss T, Zhang Q, Sun R, Wang B, Yi X, Wu Z, Gao H, Cai X, Ruan G, Zhu T, Xu C, Lou S, Yu X, Gillet L, Blattmann P, Saba K, Fankhauser CD, Schmid MB, Rutishauser D, Ljubicic J, Christiansen A, Fritz C, Rupp NJ, Poyet C, Rushing E, Weller M, Roth P, Haralambieva E, Hofer S, Chen C, Jochum W, Gao X, Teng X, Chen L, Zhong Q, Wild PJ, Aebersold R, Guo T.

Mol Oncol. 2019 Sep 8. doi: 10.1002/1878-0261.12570. [Epub ahead of print]

12.

Anticonvulsive effect of anterior thalamic deep brain stimulation in super-refractory status epilepticus crucially depends on active stimulation zone-A single case observation.

Imbach LL, Baumann CR, Poryazova R, Geissler O, Brugger P, Sarnthein J, Mothersill I, Weller M, Oertel MF, Stieglitz LH.

Seizure. 2019 Oct;71:286-288. doi: 10.1016/j.seizure.2019.08.015. Epub 2019 Aug 28. No abstract available.

PMID:
31493681
13.

FOCAD loss impacts microtubule assembly, G2/M progression and patient survival in astrocytic gliomas.

Brand F, Förster A, Christians A, Bucher M, Thomé CM, Raab MS, Westphal M, Pietsch T, von Deimling A, Reifenberger G, Claus P, Hentschel B, Weller M, Weber RG.

Acta Neuropathol. 2019 Aug 31. doi: 10.1007/s00401-019-02067-z. [Epub ahead of print]

PMID:
31473790
14.

Isolated perfused udder model for transcriptome analysis in response to Streptococcus agalactiae.

Weller MMDCA, Fonseca I, Sbardella AP, Pinto ISB, Viccini LF, Brandão HM, Gern JC, Carvalho WA, Guimarães AS, Brito MAVP, Munari DP, Silva MVGB, Martins MF.

J Dairy Res. 2019 Aug;86(3):307-314. doi: 10.1017/S0022029919000451.

PMID:
31451129
15.

Imaging challenges of immunotherapy and targeted therapy in patients with brain metastases: Response, Progression, and Pseudoprogression.

Galldiks N, Kocher M, Ceccon G, Werner JM, Brunn A, Deckert M, Pope WB, Soffietti R, Le Rhun E, Weller M, Tonn JC, Fink GR, Langen KJ.

Neuro Oncol. 2019 Aug 22. pii: noz147. doi: 10.1093/neuonc/noz147. [Epub ahead of print]

PMID:
31437274
16.

Cooperation of oncolytic virotherapy with VEGF-neutralizing antibody treatment in IDH wildtype glioblastoma dependends on MMP9.

Wirsching HG, Arora S, Zhang H, Szulzewsky F, Cimino PJ, Quéva C, Houghton AM, Glorioso JC, Weller M, Holland EC.

Neuro Oncol. 2019 Aug 15. pii: noz145. doi: 10.1093/neuonc/noz145. [Epub ahead of print] No abstract available.

PMID:
31412117
17.

Management of low-grade glioma: a systematic review and meta-analysis.

Brown TJ, Bota DA, van Den Bent MJ, Brown PD, Maher E, Aregawi D, Liau LM, Buckner JC, Weller M, Berger MS, Glantz M.

Neurooncol Pract. 2019 Jul;6(4):249-258. doi: 10.1093/nop/npy034. Epub 2018 Aug 18. Review.

PMID:
31386075
18.

Complementary and alternative medicine use by glioma patients in Switzerland.

Eisele G, Roelcke U, Conen K, Huber F, Weiss T, Hofer S, Heese O, Westphal M, Hertler C, Roth P, Weller M.

Neurooncol Pract. 2019 May;6(3):237-244. doi: 10.1093/nop/npy035. Epub 2018 Oct 12.

PMID:
31386047
19.

Temporal muscle thickness is an independent prognostic marker in patients with progressive glioblastoma: translational imaging analysis of the EORTC 26101 trial.

Furtner J, Genbrugge E, Gorlia T, Bendszus M, Nowosielski M, Golfinopoulos V, Weller M, van den Bent MJ, Wick W, Preusser M.

Neuro Oncol. 2019 Aug 1. pii: noz131. doi: 10.1093/neuonc/noz131. [Epub ahead of print]

PMID:
31369680
20.

Decreased fetal movements (DFM) - finding the balance.

Gardener G, Weller M, Ellwood D, Flenady V.

Aust N Z J Obstet Gynaecol. 2019 Aug;59(4):E14. doi: 10.1111/ajo.13024. No abstract available.

PMID:
31368514
21.

Synthetic lethality between BRCA1 deficiency and poly(ADP-ribose) polymerase inhibition is modulated by processing of endogenous oxidative DNA damage.

Giovannini S, Weller MC, Repmann S, Moch H, Jiricny J.

Nucleic Acids Res. 2019 Sep 26;47(17):9132-9143. doi: 10.1093/nar/gkz624.

22.

Link between Photoelectron Circular Dichroism and Fragmentation Channel in Strong Field Ionization.

Fehre K, Eckart S, Kunitski M, Janke C, Trabert D, Rist J, Weller M, Hartung A, Schmidt LPH, Jahnke T, Dörner R, Schöffler M.

J Phys Chem A. 2019 Aug 1;123(30):6491-6495. doi: 10.1021/acs.jpca.9b04210. Epub 2019 Jul 22.

PMID:
31329435
23.

How we treat glioblastoma.

Weller M, Le Rhun E, Preusser M, Tonn JC, Roth P.

ESMO Open. 2019 Jun 17;4(Suppl 2):e000520. doi: 10.1136/esmoopen-2019-000520. eCollection 2019. Review.

24.

Arming oHSV with ULBP3 drives abscopal immunity in lymphocyte-depleted glioblastoma.

Wirsching HG, Zhang H, Szulzewsky F, Arora S, Grandi P, Cimino PJ, Amankulor N, Campbell JS, McFerrin L, Pattwell SS, Ene C, Hicks A, Ball M, Yan J, Zhang J, Kumasaka D, Pierce RH, Weller M, Finer M, Quéva C, Glorioso JC, Houghton AM, Holland EC.

JCI Insight. 2019 Jul 11;4(13). pii: 128217. doi: 10.1172/jci.insight.128217. eCollection 2019 Jul 11.

25.

Long-term complications and reconstruction failures in previously radiated breast cancer patients receiving salvage mastectomy with autologous reconstruction or tissue expander/implant-based reconstruction.

Manyam BV, Shah C, Woody NM, Reddy CA, Weller MA, Juloori A, Naik M, Valente S, Grobmyer S, Durand P, Djohan R, Tendulkar RD.

Breast J. 2019 Jul 1. doi: 10.1111/tbj.13428. [Epub ahead of print]

PMID:
31264293
26.

Long-Term Outcomes After Autologous or Tissue Expander/Implant-Based Breast Reconstruction and Postmastectomy Radiation for Breast Cancer.

Manyam BV, Shah C, Woody NM, Reddy CA, Weller MA, Juloori A, Naik M, Valente S, Grobmyer S, Durand P, Djohan R, Tendulkar RD.

Pract Radiat Oncol. 2019 Jun 22. pii: S1879-8500(19)30179-1. doi: 10.1016/j.prro.2019.06.008. [Epub ahead of print]

PMID:
31238166
27.

How we treat patients with leptomeningeal metastases.

Le Rhun E, Preusser M, van den Bent M, Andratschke N, Weller M.

ESMO Open. 2019 May 21;4(Suppl 2):e000507. doi: 10.1136/esmoopen-2019-000507. eCollection 2019. Review.

28.

Data Sets for the Reporting of Tumors of the Central Nervous System.

Louis DN, Wesseling P, Brandner S, Brat DJ, Ellison DW, Giangaspero F, Hattab EM, Hawkins C, Judge MJ, Kleinschmidt-DeMasters B, Komori T, McLean C, Paulus W, Perry A, Reifenberger G, Weller M, Rous B.

Arch Pathol Lab Med. 2019 Jun 20. doi: 10.5858/arpa.2018-0565-OA. [Epub ahead of print]

PMID:
31219344
29.

The added value of health-related quality of life as a prognostic indicator of overall survival and progression-free survival in glioma patients: a meta-analysis based on individual patient data from randomised controlled trials.

Coomans M, Dirven L, K Aaronson N, Baumert BG, van den Bent M, Bottomley A, Brandes AA, Chinot O, Coens C, Gorlia T, Herrlinger U, Keime-Guibert F, Malmström A, Martinelli F, Stupp R, Talacchi A, Weller M, Wick W, Reijneveld JC, Taphoorn MJB; EORTC Quality of Life Group and the EORTC Brain Tumor Group.

Eur J Cancer. 2019 Jul;116:190-198. doi: 10.1016/j.ejca.2019.05.012. Epub 2019 Jun 13.

PMID:
31203194
30.

Barriers to Accrual and Enrollment in Brain Tumor Trials.

Lee EQ, Chukwueke UN, Hervey-Jumper SL, de Groot JF, Leone JP, Armstrong TS, Chang SM, Arons D, Oliver K, Verble K, Musella A, Willmarth N, Alexander BM, Bates A, Doherty L, Galanis E, Gaffey S, Halkin T, Friday BE, Fouladi M, Lin NU, Macdonald D, Mehta MP, Penas-Prado M, Vogelbaum MA, Sahebjam S, Sandak D, van den Bent M, Weller M, Reardon DA, Wen PY.

Neuro Oncol. 2019 Jun 7. pii: noz104. doi: 10.1093/neuonc/noz104. [Epub ahead of print]

PMID:
31175826
31.

DNA methylation profiling to predict recurrence risk in meningioma: development and validation of a nomogram to optimize clinical management.

Nassiri F, Mamatjan Y, Suppiah S, Badhiwala JH, Mansouri S, Karimi S, Saarela O, Poisson L, Gepfner-Tuma I, Schittenhelm J, Ng HK, Noushmehr H, Harter P, Baumgarten P, Weller M, Preusser M, Herold-Mende C, Tatagiba M, Tabatabai G, Sahm F, von Deimling A, Zadeh G, Aldape KD; International Consortium on Meningiomas .

Neuro Oncol. 2019 Jun 3. pii: noz061. doi: 10.1093/neuonc/noz061. [Epub ahead of print]

PMID:
31158293
32.

Defining EGFR amplification status for clinical trial inclusion.

French PJ, Eoli M, Sepulveda JM, de Heer I, Kros JM, Walenkamp A, Frenel JS, Franceschi E, Clement PM, Weller M, Ansell P, Looman J, Bain E, Morfouace M, Gorlia T, van den Bent M.

Neuro Oncol. 2019 Oct 9;21(10):1263-1272. doi: 10.1093/neuonc/noz096.

33.

Equal Footing of Thermal Expansion and Electron-Phonon Interaction in the Temperature Dependence of Lead Halide Perovskite Band Gaps.

Francisco-López A, Charles B, Weber OJ, Alonso MI, Garriga M, Campoy-Quiles M, Weller MT, Goñi AR.

J Phys Chem Lett. 2019 Jun 6;10(11):2971-2977. doi: 10.1021/acs.jpclett.9b00876. Epub 2019 May 22.

PMID:
31091105
34.

Imaging necrosis during treatment is associated with worse survival in EORTC 26101 study.

Nowosielski M, Gorlia T, Bromberg JEC, Sahm F, Harting I, Kickingereder P, Brandes AA, Taphoorn MJB, Taal W, Domont J, Idbaih A, Campone M, Clement PM, Weller M, Fabbro M, Le Rhun E, Platten M, Golfinopoulos V, van den Bent MJ, Bendszus M, Wick W.

Neurology. 2019 Jun 11;92(24):e2754-e2763. doi: 10.1212/WNL.0000000000007643. Epub 2019 May 10.

PMID:
31076534
35.

[Challenges and future perspectives in neuro-oncology].

Tabatabai G, Weller M.

Nervenarzt. 2019 Jun;90(6):594-600. doi: 10.1007/s00115-019-0716-4. Review. German.

PMID:
31073670
36.

Mutational patterns and regulatory networks in epigenetic subgroups of meningioma.

Paramasivam N, Hübschmann D, Toprak UH, Ishaque N, Neidert M, Schrimpf D, Stichel D, Reuss D, Sievers P, Reinhardt A, Wefers AK, Jones DTW, Gu Z, Werner J, Uhrig S, Wirsching HG, Schick M, Bewerunge-Hudler M, Beck K, Brehmer S, Urbschat S, Seiz-Rosenhagen M, Hänggi D, Herold-Mende C, Ketter R, Eils R, Ram Z, Pfister SM, Wick W, Weller M, Grossmann R, von Deimling A, Schlesner M, Sahm F.

Acta Neuropathol. 2019 Aug;138(2):295-308. doi: 10.1007/s00401-019-02008-w. Epub 2019 May 8.

PMID:
31069492
37.

Vulnerability of invasive glioblastoma cells to lysosomal membrane destabilization.

Le Joncour V, Filppu P, Hyvönen M, Holopainen M, Turunen SP, Sihto H, Burghardt I, Joensuu H, Tynninen O, Jääskeläinen J, Weller M, Lehti K, Käkelä R, Laakkonen P.

EMBO Mol Med. 2019 Jun;11(6). pii: e9034. doi: 10.15252/emmm.201809034.

38.

Efficient Screening of Combinatorial Peptide Libraries by Spatially Ordered Beads Immobilized on Conventional Glass Slides.

Schwaar T, Lettow M, Remmler D, Börner HG, Weller MG.

High Throughput. 2019 Apr 30;8(2). pii: E11. doi: 10.3390/ht8020011.

39.

Differential Impact of Education Level, Occupation and Marital Status on Performance of the Papanicolaou Test among Women from Various Regions in Brazil

Açucena Vieira Alves S, Schiaveto de Souza A, Weller M, Pires Batiston A.

Asian Pac J Cancer Prev. 2019 Apr 29;20(4):1037-1044.

40.

DNA methylation, transcriptome and genetic copy number signatures of diffuse cerebral WHO grade II/III gliomas resolve cancer heterogeneity and development.

Binder H, Willscher E, Loeffler-Wirth H, Hopp L, Jones DTW, Pfister SM, Kreuz M, Gramatzki D, Fortenbacher E, Hentschel B, Tatagiba M, Herrlinger U, Vatter H, Matschke J, Westphal M, Krex D, Schackert G, Tonn JC, Schlegel U, Steiger HJ, Wick W, Weber RG, Weller M, Loeffler M.

Acta Neuropathol Commun. 2019 Apr 25;7(1):59. doi: 10.1186/s40478-019-0704-8.

41.

Use of metformin and outcome of patients with newly diagnosed glioblastoma: Pooled analysis.

Seliger C, Genbrugge E, Gorlia T, Chinot O, Stupp R, Nabors B, Weller M, Hau P; EORTC Brain Tumor Group.

Int J Cancer. 2019 Apr 13. doi: 10.1002/ijc.32337. [Epub ahead of print]

PMID:
30980539
42.

Laser-Induced Microplasma as an Ambient Ionization Approach for the Mass-Spectrometric Analysis of Liquid Samples.

Bierstedt A, You Y, van Wasen S, Bosc-Bierne G, Weller M, Riedel J.

Anal Chem. 2019 May 7;91(9):5922-5928. doi: 10.1021/acs.analchem.9b00329. Epub 2019 Apr 11.

PMID:
30933486
43.

Patient experiences in behavioral health integrated primary care settings: the role of stigma in shaping patient outcomes over time.

Royal Kenton N, Broffman L, Jones K, Albrecht Mcmenamin K, Weller M, Brown K, Currier J, Wright B.

Psychol Health Med. 2019 Dec;24(10):1182-1197. doi: 10.1080/13548506.2019.1595685. Epub 2019 Mar 29.

PMID:
30924365
44.

Evolutionary Trajectories of IDHWT Glioblastomas Reveal a Common Path of Early Tumorigenesis Instigated Years ahead of Initial Diagnosis.

Körber V, Yang J, Barah P, Wu Y, Stichel D, Gu Z, Fletcher MNC, Jones D, Hentschel B, Lamszus K, Tonn JC, Schackert G, Sabel M, Felsberg J, Zacher A, Kaulich K, Hübschmann D, Herold-Mende C, von Deimling A, Weller M, Radlwimmer B, Schlesner M, Reifenberger G, Höfer T, Lichter P.

Cancer Cell. 2019 Apr 15;35(4):692-704.e12. doi: 10.1016/j.ccell.2019.02.007. Epub 2019 Mar 21.

PMID:
30905762
45.

Enantioselective fragmentation of an achiral molecule in a strong laser field.

Fehre K, Eckart S, Kunitski M, Pitzer M, Zeller S, Janke C, Trabert D, Rist J, Weller M, Hartung A, Schmidt LPH, Jahnke T, Berger R, Dörner R, Schöffler MS.

Sci Adv. 2019 Mar 8;5(3):eaau7923. doi: 10.1126/sciadv.aau7923. eCollection 2019 Mar.

46.

Immunotherapy for glioblastoma: quo vadis?

Weller M, Le Rhun E.

Nat Rev Clin Oncol. 2019 Jul;16(7):405-406. doi: 10.1038/s41571-019-0195-3. No abstract available.

PMID:
30867572
47.

CHD7 promotes glioblastoma cell motility and invasiveness through transcriptional modulation of an invasion signature.

Machado RAC, Schneider H, DeOcesano-Pereira C, Lichtenstein F, Andrade F, Fujita A, Trombetta-Lima M, Weller M, Bowman-Colin C, Sogayar MC.

Sci Rep. 2019 Mar 8;9(1):3952. doi: 10.1038/s41598-019-39564-w.

48.

Lomustine-temozolomide combination therapy versus standard temozolomide therapy in patients with newly diagnosed glioblastoma with methylated MGMT promoter (CeTeG/NOA-09): a randomised, open-label, phase 3 trial.

Herrlinger U, Tzaridis T, Mack F, Steinbach JP, Schlegel U, Sabel M, Hau P, Kortmann RD, Krex D, Grauer O, Goldbrunner R, Schnell O, Bähr O, Uhl M, Seidel C, Tabatabai G, Kowalski T, Ringel F, Schmidt-Graf F, Suchorska B, Brehmer S, Weyerbrock A, Renovanz M, Bullinger L, Galldiks N, Vajkoczy P, Misch M, Vatter H, Stuplich M, Schäfer N, Kebir S, Weller J, Schaub C, Stummer W, Tonn JC, Simon M, Keil VC, Nelles M, Urbach H, Coenen M, Wick W, Weller M, Fimmers R, Schmid M, Hattingen E, Pietsch T, Coch C, Glas M; Neurooncology Working Group of the German Cancer Society.

Lancet. 2019 Feb 16;393(10172):678-688. doi: 10.1016/S0140-6736(18)31791-4. Epub 2019 Feb 14.

PMID:
30782343
49.

Ten-Year Outcomes of Moderately Hypofractionated (70 Gy in 28 fractions) Intensity Modulated Radiation Therapy for Localized Prostate Cancer.

Abu-Gheida I, Reddy CA, Kotecha R, Weller MA, Shah C, Kupelian PA, Mian O, Ciezki JP, Stephans KL, Tendulkar RD.

Int J Radiat Oncol Biol Phys. 2019 Jun 1;104(2):325-333. doi: 10.1016/j.ijrobp.2019.01.091. Epub 2019 Feb 2.

PMID:
30721720
50.

The RANO Leptomeningeal Metastasis Group proposal to assess response to treatment: lack of feasibility and clinical utility and a revised proposal.

Le Rhun E, Devos P, Boulanger T, Smits M, Brandsma D, Rudà R, Furtner J, Hempel JM, Postma TJ, Roth P, Snijders TJ, Winkler F, Winklhofer S, Castellano A, Hattingen E, Capellades J, Gorlia T, Van den Bent M, Wen PY, Bendszus M, Weller M; European Organisation for Research and Treatment of Cancer (EORTC) Brain Tumor Group (BTG) Central Nervous System (CNS) Metastases Committee and the EORTC BTG Imaging Committee.

Neuro Oncol. 2019 May 6;21(5):648-658. doi: 10.1093/neuonc/noz024.

PMID:
30715514

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