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Items: 25

1.

CP-465,022, a selective noncompetitive AMPA receptor antagonist, blocks AMPA receptors but is not neuroprotective in vivo.

Menniti FS, Buchan AM, Chenard BL, Critchett DJ, Ganong AH, Guanowsky V, Seymour PA, Welch WM.

Stroke. 2003 Jan;34(1):171-6.

PMID:
12511770
2.

Discovery of a series of (4,5-dihydroimidazol-2-yl)-biphenylamine 5-HT7 agonists.

Parikh V, Welch WM, Schmidt AW.

Bioorg Med Chem Lett. 2003 Jan 20;13(2):269-71.

PMID:
12482437
3.

Functional characterization of CP-465,022, a selective, noncompetitive AMPA receptor antagonist.

Lazzaro JT, Paternain AV, Lerma J, Chenard BL, Ewing FE, Huang J, Welch WM, Ganong AH, Menniti FS.

Neuropharmacology. 2002 Feb;42(2):143-53.

PMID:
11804610
4.

Quinazolin-4-one alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonists: structure-activity relationship of the C-2 side chain tether.

Chenard BL, Welch WM, Blake JF, Butler TW, Reinhold A, Ewing FE, Menniti FS, Pagnozzi MJ.

J Med Chem. 2001 May 24;44(11):1710-7.

PMID:
11356106
5.

Atropisomeric quinazolin-4-one derivatives are potent noncompetitive alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonists.

Welch WM, Ewing FE, Huang J, Menniti FS, Pagnozzi MJ, Kelly K, Seymour PA, Guanowsky V, Guhan S, Guinn MR, Critchett D, Lazzaro J, Ganong AH, DeVries KM, Staigers TL, Chenard BL.

Bioorg Med Chem Lett. 2001 Jan 22;11(2):177-81.

PMID:
11206453
6.

Characterization of the binding site for a novel class of noncompetitive alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonists.

Menniti FS, Chenard BL, Collins MB, Ducat MF, Elliott ML, Ewing FE, Huang JI, Kelly KA, Lazzaro JT, Pagnozzi MJ, Weeks JL, Welch WM, White WF.

Mol Pharmacol. 2000 Dec;58(6):1310-7.

PMID:
11093768
7.

Methaqualone derivatives are potent noncompetitive AMPA receptor antagonists.

Chenard BL, Menniti FS, Pagnozzi MJ, Shenk KD, Ewing FE, Welch WM.

Bioorg Med Chem Lett. 2000 Jun 5;10(11):1203-5.

PMID:
10866381
8.

Spiro hydantoin aldose reductase inhibitors derived from 8-aza-4-chromanones.

Sarges R, Goldstein SW, Welch WM, Swindell AC, Siegel TW, Beyer TA.

J Med Chem. 1990 Jul;33(7):1859-65.

PMID:
2113948
9.

[3H] sertraline binding to rat brain membranes.

Koe BK, Lebel LA, Welch WM.

Psychopharmacology (Berl). 1990;100(4):470-6.

PMID:
2138796
10.

Metabolism and disposition of the 5-hydroxytryptamine uptake blocker sertraline in the rat and dog.

Tremaine LM, Welch WM, Ronfeld RA.

Drug Metab Dispos. 1989 Sep-Oct;17(5):542-50.

PMID:
2573498
11.

Structure-activity relationships of 6-(heterocyclyl)-methylene penam sulfones; a new class of beta-lactamase inhibitors.

Chen YL, Chang CW, Hedberg K, Guarino K, Welch WM, Kiessling L, Retsema JA, Haskell SL, Anderson M, Manousos M, et al.

J Antibiot (Tokyo). 1987 Jun;40(6):803-22.

12.

Neuroleptics from the 4a,9b-trans-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole series. 3. Carboxamidoalkyl derivatives.

Welch WM, Harbert CA, Sarges R, Weissman A, Koe BK.

J Med Chem. 1986 Oct;29(10):2108-11.

PMID:
2876105
13.

Neuroleptics from the 4a,9b-cis- and 4a,9b-trans-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole series. 2.

Welch WM, Harbert CA, Weissman A, Koe BK.

J Med Chem. 1986 Oct;29(10):2093-9.

PMID:
2876102
14.

Neuroleptic activity of chiral trans-hexahydro-gamma-carbolines.

Sarges R, Howard HR, Donahue KM, Welch WM, Dominy BW, Weissman A, Koe BK, Bordner J.

J Med Chem. 1986 Jan;29(1):8-19. Erratum in: J Med Chem 1986 May;29(5):876.

PMID:
3941416
15.

Nontricyclic antidepressant agents derived from cis- and trans-1-amino-4-aryltetralins.

Welch WM, Kraska AR, Sarges R, Koe BK.

J Med Chem. 1984 Nov;27(11):1508-15.

PMID:
6492080
16.
17.
18.
19.

Neuroleptic 4-aryltetrahydropyrrolo[3,4-b]indoles.

Welch WM, Harbert CA, Weissman A.

J Med Chem. 1980 Jun;23(6):704-7.

PMID:
6104734
20.

Neuroleptic activity in 5-aryltetrahydro-gamma-carbolines.

Harbert CA, Plattner JJ, Welch WM, Weissman A, Koe BK.

J Med Chem. 1980 Jun;23(6):635-43.

PMID:
6104732
21.

Neuroleptic activity of the 5-aryltetrahydro-gamma-carboline series. Conformational requirements for interaction with central dopamine receptors.

Harbert CA, Plattner JJ, Welch WM, Weissman A, Koe BK.

Mol Pharmacol. 1980 Jan;17(1):38-42. No abstract available.

PMID:
6104285
22.

Analgesic and tranquilizing activity of 5,8-disubstituted 2-aminomethyl-3,4-dihydronaphthalenes.

Welch WM, Plattner JJ, Stratten WP, Harbert CA.

J Med Chem. 1978 Mar;21(3):257-63.

PMID:
628000
23.

Analgesic and tranquilizing activity of 5,8-disubstituted 1-tetralone Mannich bases.

Welch WM, Harbert CA, Sarges R, Stratten WP, Weissman A.

J Med Chem. 1977 May;20(5):699-705.

PMID:
853506
24.

Pharmacokinetics of thiothixene in man.

Hobbs DC, Welch WM, Short MJ, Moody WA, Van der Velde CD.

Clin Pharmacol Ther. 1974 Sep;16(3):473-8. No abstract available.

PMID:
4415039
25.

Report of Committee on the Relative Immunizing Value of Human and Bovine Vaccine Virus.

Bryce PH, Welch WM, Liceaga E.

Public Health Pap Rep. 1902;28:146-59. No abstract available.

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