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Evaluating glial and neuronal blood biomarkers GFAP and UCH-L1 as gradients of brain injury in concussive, subconcussive and non-concussive trauma: a prospective cohort study.

Papa L, Zonfrillo MR, Welch RD, Lewis LM, Braga CF, Tan CN, Ameli NJ, Lopez MA, Haeussler CA, Mendez Giordano D, Giordano PA, Ramirez J, Mittal MK.

BMJ Paediatr Open. 2019 Aug 25;3(1):e000473. doi: 10.1136/bmjpo-2019-000473. eCollection 2019.


Self-Driven Phase Transitions Drive Myxococcus xanthus Fruiting Body Formation.

Liu G, Patch A, Bahar F, Yllanes D, Welch RD, Marchetti MC, Thutupalli S, Shaevitz JW.

Phys Rev Lett. 2019 Jun 21;122(24):248102. doi: 10.1103/PhysRevLett.122.248102.


Scientific Letter to the Editor: Need for a Definitive Study of Global Longitudinal Strain for Prognostication in Septic Cardiomyopathy.

Ehrman RR, Moore SC, Favot MJ, Akers KG, Gallien JZ, Welch RD, Abidov A, Sherwin RL, Levy PD.

J Am Soc Echocardiogr. 2019 Apr;32(4):549-552.e3. doi: 10.1016/j.echo.2018.12.005. Epub 2019 Feb 6. No abstract available.


Serum GFAP and UCH-L1 for prediction of absence of intracranial injuries on head CT (ALERT-TBI): a multicentre observational study.

Bazarian JJ, Biberthaler P, Welch RD, Lewis LM, Barzo P, Bogner-Flatz V, Gunnar Brolinson P, Büki A, Chen JY, Christenson RH, Hack D, Huff JS, Johar S, Jordan JD, Leidel BA, Lindner T, Ludington E, Okonkwo DO, Ornato J, Peacock WF, Schmidt K, Tyndall JA, Vossough A, Jagoda AS.

Lancet Neurol. 2018 Sep;17(9):782-789. doi: 10.1016/S1474-4422(18)30231-X. Epub 2018 Jul 24.


Pharmacological inhibition of REV-ERB stimulates differentiation, inhibits turnover and reduces fibrosis in dystrophic muscle.

Welch RD, Billon C, Valfort AC, Burris TP, Flaveny CA.

Sci Rep. 2017 Dec 7;7(1):17142. doi: 10.1038/s41598-017-17496-7.


Rev-Erb co-regulates muscle regeneration via tethered interaction with the NF-Y cistrome.

Welch RD, Guo C, Sengupta M, Carpenter KJ, Stephens NA, Arnett SA, Meyers MJ, Sparks LM, Smith SR, Zhang J, Burris TP, Flaveny CA.

Mol Metab. 2017 May 19;6(7):703-714. doi: 10.1016/j.molmet.2017.05.001. eCollection 2017 Jul.


REV-ERB and ROR: therapeutic targets for treating myopathies.

Welch RD, Flaveny CA.

Phys Biol. 2017 Jun 6;14(4):045002. doi: 10.1088/1478-3975/14/4/045002. Review.


Utility of Serum Biomarkers in the Diagnosis and Stratification of Mild Traumatic Brain Injury.

Lewis LM, Schloemann DT, Papa L, Fucetola RP, Bazarian J, Lindburg M, Welch RD.

Acad Emerg Med. 2017 Jun;24(6):710-720. doi: 10.1111/acem.13174. Epub 2017 May 18.


Modeling the Kinetics of Serum Glial Fibrillary Acidic Protein, Ubiquitin Carboxyl-Terminal Hydrolase-L1, and S100B Concentrations in Patients with Traumatic Brain Injury.

Welch RD, Ellis M, Lewis LM, Ayaz SI, Mika VH, Millis S, Papa L.

J Neurotrauma. 2017 Jun 1;34(11):1957-1971. doi: 10.1089/neu.2016.4772. Epub 2017 Feb 27.


Utility of point of care assessment of platelet reactivity (using the PFA-100®) to aid in diagnosis of stroke.

Pearson C, Przyklenk K, Mika VH, Ayaz SI, Ellis M, Varade P, Tolomello R, Welch RD.

Am J Emerg Med. 2017 May;35(5):802.e1-802.e5. doi: 10.1016/j.ajem.2016.11.036. Epub 2016 Nov 15.


Trends in the Incidence of Hypertensive Emergencies in US Emergency Departments From 2006 to 2013.

Janke AT, McNaughton CD, Brody AM, Welch RD, Levy PD.

J Am Heart Assoc. 2016 Dec 5;5(12). pii: e004511.


Inter-laboratory evolution of a model organism and its epistatic effects on mutagenesis screens.

Bradley MD, Neu D, Bahar F, Welch RD.

Sci Rep. 2016 Dec 1;6:38001. doi: 10.1038/srep38001.


Impact of Palliative Care Screening and Consultation in the ICU: A Multihospital Quality Improvement Project.

Zalenski RJ, Jones SS, Courage C, Waselewsky DR, Kostaroff AS, Kaufman D, Beemath A, Brofman J, Castillo JW, Krayem H, Marinelli A, Milner B, Palleschi MT, Tareen M, Testani S, Soubani A, Walch J, Wheeler J, Wilborn S, Granovsky H, Welch RD.

J Pain Symptom Manage. 2017 Jan;53(1):5-12.e3. doi: 10.1016/j.jpainsymman.2016.08.003. Epub 2016 Oct 5.


Severe hypothermia and cardiac arrest successfully treated without external mechanical circulatory support.

Ellis MM, Welch RD.

Am J Emerg Med. 2016 Sep;34(9):1913.e5-6. doi: 10.1016/j.ajem.2016.02.021. Epub 2016 Feb 12. No abstract available.


Results of a Hospital-Based Palliative Care Intervention for Patients With an Acute Exacerbation of Chronic Heart Failure.

Hopp FP, Zalenski RJ, Waselewsky D, Burn J, Camp J, Welch RD, Levy P.

J Card Fail. 2016 Dec;22(12):1033-1036. doi: 10.1016/j.cardfail.2016.04.004. Epub 2016 Apr 11.


Time Course and Diagnostic Accuracy of Glial and Neuronal Blood Biomarkers GFAP and UCH-L1 in a Large Cohort of Trauma Patients With and Without Mild Traumatic Brain Injury.

Papa L, Brophy GM, Welch RD, Lewis LM, Braga CF, Tan CN, Ameli NJ, Lopez MA, Haeussler CA, Mendez Giordano DI, Silvestri S, Giordano P, Weber KD, Hill-Pryor C, Hack DC.

JAMA Neurol. 2016 May 1;73(5):551-60. doi: 10.1001/jamaneurol.2016.0039.


Compensation through Functional Hyperconnectivity: A Longitudinal Connectome Assessment of Mild Traumatic Brain Injury.

Iraji A, Chen H, Wiseman N, Welch RD, O'Neil BJ, Haacke EM, Liu T, Kou Z.

Neural Plast. 2016;2016:4072402. doi: 10.1155/2016/4072402. Epub 2015 Dec 27.


Ability of Serum Glial Fibrillary Acidic Protein, Ubiquitin C-Terminal Hydrolase-L1, and S100B To Differentiate Normal and Abnormal Head Computed Tomography Findings in Patients with Suspected Mild or Moderate Traumatic Brain Injury.

Welch RD, Ayaz SI, Lewis LM, Unden J, Chen JY, Mika VH, Saville B, Tyndall JA, Nash M, Buki A, Barzo P, Hack D, Tortella FC, Schmid K, Hayes RL, Vossough A, Sweriduk ST, Bazarian JJ.

J Neurotrauma. 2016 Jan 15;33(2):203-14. doi: 10.1089/neu.2015.4149. Epub 2015 Dec 18.


Response to "An approach to markedly elevated blood pressure in hypertensive patients without acute organ damage".

Levy PD, Welch RD.

Am J Emerg Med. 2015 Dec;33(12):1831-2. doi: 10.1016/j.ajem.2015.06.051. Epub 2015 Jul 7. No abstract available.


Blood pressure treatment and outcomes in hypertensive patients without acute target organ damage: a retrospective cohort.

Levy PD, Mahn JJ, Miller J, Shelby A, Brody A, Davidson R, Burla MJ, Marinica A, Carroll J, Purakal J, Flack JM, Welch RD.

Am J Emerg Med. 2015 Sep;33(9):1219-24. doi: 10.1016/j.ajem.2015.05.036. Epub 2015 May 30.


Effectiveness of an urban emergency department call-back system in the successful linkage to treatment of sexually transmitted infections.

Lolar SA, Sherwin RL, Robinson DM, Courage C, Welch RD.

South Med J. 2015 May;108(5):268-73. doi: 10.14423/SMJ.0000000000000273.


The LXR inverse agonist SR9238 suppresses fibrosis in a model of non-alcoholic steatohepatitis.

Griffett K, Welch RD, Flaveny CA, Kolar GR, Neuschwander-Tetri BA, Burris TP.

Mol Metab. 2015 Feb 9;4(4):353-7. doi: 10.1016/j.molmet.2015.01.009. eCollection 2015 Apr.


Cerebral hemodynamic changes of mild traumatic brain injury at the acute stage.

Doshi H, Wiseman N, Liu J, Wang W, Welch RD, O'Neil BJ, Zuk C, Wang X, Mika V, Szaflarski JP, Haacke EM, Kou Z.

PLoS One. 2015 Feb 6;10(2):e0118061. doi: 10.1371/journal.pone.0118061. eCollection 2015. Erratum in: PLoS One. 2015;10(5):e0127487. PLoS One. 2015;10(7):e0132750.


Intramuscular midazolam versus intravenous lorazepam for the prehospital treatment of status epilepticus in the pediatric population.

Welch RD, Nicholas K, Durkalski-Mauldin VL, Lowenstein DH, Conwit R, Mahajan PV, Lewandowski C, Silbergleit R; Neurological Emergencies Treatment Trials (NETT) Network Investigators.

Epilepsia. 2015 Feb;56(2):254-62. doi: 10.1111/epi.12905. Epub 2015 Jan 17.


Anaphylactic reaction after ongoing exposure to hair glue: a novel case report.

Burla MJ, Brody AM, Welch RD, Favot MJ.

J Emerg Med. 2015 Jan;48(1):e5-7. doi: 10.1016/j.jemermed.2014.09.036. Epub 2014 Nov 6.


Access to care issues and the role of EDs in the wake of the Affordable Care Act.

Janke AT, Brody AM, Overbeek DL, Bedford JC, Welch RD, Levy PD.

Am J Emerg Med. 2015 Feb;33(2):181-5. doi: 10.1016/j.ajem.2014.11.006. Epub 2014 Nov 13.


Resting State Functional Connectivity in Mild Traumatic Brain Injury at the Acute Stage: Independent Component and Seed-Based Analyses.

Iraji A, Benson RR, Welch RD, O'Neil BJ, Woodard JL, Ayaz SI, Kulek A, Mika V, Medado P, Soltanian-Zadeh H, Liu T, Haacke EM, Kou Z.

J Neurotrauma. 2015 Jul 15;32(14):1031-45. doi: 10.1089/neu.2014.3610. Epub 2015 Mar 6.


Describing Myxococcus xanthus aggregation using Ostwald ripening equations for thin liquid films.

Bahar F, Pratt-Szeliga PC, Angus S, Guo J, Welch RD.

Sci Rep. 2014 Sep 18;4:6376. doi: 10.1038/srep06376.


Phenotypic profiling of ABC transporter coding genes in Myxococcus xanthus.

Yan J, Bradley MD, Friedman J, Welch RD.

Front Microbiol. 2014 Jul 18;5:352. doi: 10.3389/fmicb.2014.00352. eCollection 2014.


Point-of-care assessment of platelet reactivity in the emergency department may facilitate rapid rule-out of acute coronary syndromes: a prospective cohort pilot feasibility study.

Darling CE, Sala Mercado JA, Quiroga-Castro W, Tecco GF, Zelaya FR, Conci EC, Sala JP, Smith CS, Michelson AD, Whittaker P, Welch RD, Przyklenk K.

BMJ Open. 2014 Jan 17;4(1):e003883. doi: 10.1136/bmjopen-2013-003883.


Combining biochemical and imaging markers to improve diagnosis and characterization of mild traumatic brain injury in the acute setting: results from a pilot study.

Kou Z, Gattu R, Kobeissy F, Welch RD, O'Neil BJ, Woodard JL, Ayaz SI, Kulek A, Kas-Shamoun R, Mika V, Zuk C, Tomasello F, Mondello S.

PLoS One. 2013 Nov 19;8(11):e80296. doi: 10.1371/journal.pone.0080296. eCollection 2013.


A Markovian analysis of bacterial genome sequence constraints.

Skewes AD, Welch RD.

PeerJ. 2013 Aug 29;1:e127. doi: 10.7717/peerj.127. eCollection 2013.


Traumatic intracranial hemorrhage, value in health care, and being important.

Carr BG, Welch RD.

Ann Emerg Med. 2013 May;61(5):518-9. doi: 10.1016/j.annemergmed.2012.10.032. Epub 2012 Dec 20. No abstract available.


A Clp/Hsp100 chaperone functions in Myxococcus xanthus sporulation and self-organization.

Yan J, Garza AG, Bradley MD, Welch RD.

J Bacteriol. 2012 Apr;194(7):1689-96. doi: 10.1128/JB.06492-11. Epub 2012 Jan 27.


The entomopathogenic bacterial endosymbionts Xenorhabdus and Photorhabdus: convergent lifestyles from divergent genomes.

Chaston JM, Suen G, Tucker SL, Andersen AW, Bhasin A, Bode E, Bode HB, Brachmann AO, Cowles CE, Cowles KN, Darby C, de Léon L, Drace K, Du Z, Givaudan A, Herbert Tran EE, Jewell KA, Knack JJ, Krasomil-Osterfeld KC, Kukor R, Lanois A, Latreille P, Leimgruber NK, Lipke CM, Liu R, Lu X, Martens EC, Marri PR, Médigue C, Menard ML, Miller NM, Morales-Soto N, Norton S, Ogier JC, Orchard SS, Park D, Park Y, Qurollo BA, Sugar DR, Richards GR, Rouy Z, Slominski B, Slominski K, Snyder H, Tjaden BC, van der Hoeven R, Welch RD, Wheeler C, Xiang B, Barbazuk B, Gaudriault S, Goodner B, Slater SC, Forst S, Goldman BS, Goodrich-Blair H.

PLoS One. 2011;6(11):e27909. doi: 10.1371/journal.pone.0027909. Epub 2011 Nov 18.


Xanthusbase after five years expands to become Openmods.

Pratt-Szeliga PC, Skewes AD, Yan J, Welch LG, Welch RD.

Nucleic Acids Res. 2012 Jan;40(Database issue):D1288-94. doi: 10.1093/nar/gkr1054. Epub 2011 Nov 23.


Quantifying aggregation dynamics during Myxococcus xanthus development.

Zhang H, Angus S, Tran M, Xie C, Igoshin OA, Welch RD.

J Bacteriol. 2011 Oct;193(19):5164-70. doi: 10.1128/JB.05188-11. Epub 2011 Jul 22.


Recording multicellular behavior in Myxococcus xanthus biofilms using time-lapse microcinematography.

Taylor RG, Welch RD.

J Vis Exp. 2010 Aug 6;(42). pii: 2038. doi: 10.3791/2038.


Does aspirin use adversely influence intermediate-term postdischarge outcomes for hospitalized patients who are treated with angiotensin-converting enzyme inhibitors or angiotensin receptor blockers? Findings from Organized Program to Facilitate Life-Saving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF).

Levy PD, Nandyal D, Welch RD, Sun JL, Pieper K, Ghali JK, Fonarow GC, Gheorghiade M, O'Connor CM.

Am Heart J. 2010 Feb;159(2):222-230.e2. doi: 10.1016/j.ahj.2009.11.009. Erratum in: Am Heart J. 2010 Jul;160(1):208.


Factors associated with neurologically intact survival for patients with acute heart failure and in-hospital cardiac arrest.

Levy PD, Ye H, Compton S, Chan PS, Larkin GL, Welch RD; American Heart Association National Registry of Cardiopulmonary Resuscitation Investigators.

Circ Heart Fail. 2009 Nov;2(6):572-81. doi: 10.1161/CIRCHEARTFAILURE.108.828095. Epub 2009 Sep 28.


Successful treatment of unicameral bone cyst by single percutaneous injection of alpha-BSM.

Thawrani D, Thai CC, Welch RD, Copley L, Johnston CE.

J Pediatr Orthop. 2009 Jul-Aug;29(5):511-7. doi: 10.1097/BPO.0b013e3181aad704.


Chemotaxis as an emergent property of a swarm.

Taylor RG, Welch RD.

J Bacteriol. 2008 Oct;190(20):6811-6. doi: 10.1128/JB.00662-08. Epub 2008 Aug 22.


The emerging world of wikis.

Hu JC, Aramayo R, Bolser D, Conway T, Elsik CG, Gribskov M, Kelder T, Kihara D, Knight TF Jr, Pico AR, Siegele DA, Wanner BL, Welch RD.

Science. 2008 Jun 6;320(5881):1289-90. doi: 10.1126/science.320.5881.1289b. No abstract available.


Inflammatory markers at hospital discharge predict subsequent mortality after pneumonia and sepsis.

Yende S, D'Angelo G, Kellum JA, Weissfeld L, Fine J, Welch RD, Kong L, Carter M, Angus DC; GenIMS Investigators.

Am J Respir Crit Care Med. 2008 Jun 1;177(11):1242-7. doi: 10.1164/rccm.200712-1777OC. Epub 2008 Mar 27.


The effect of clinical experience on the error rate of emergency physicians.

Berk WA, Welch RD, Levy PD, Jones JT, Arthur C, Kuhn GJ, King JJ, Bock BF, Sweeny PJ.

Ann Emerg Med. 2008 Nov;52(5):497-501. doi: 10.1016/j.annemergmed.2008.01.329. Epub 2008 Mar 19.


Practical applications of bacterial functional genomics.

Suen G, Arshinoff BI, Taylor RG, Welch RD.

Biotechnol Genet Eng Rev. 2007;24:213-42. Review. No abstract available.


Complete genome sequence of the myxobacterium Sorangium cellulosum.

Schneiker S, Perlova O, Kaiser O, Gerth K, Alici A, Altmeyer MO, Bartels D, Bekel T, Beyer S, Bode E, Bode HB, Bolten CJ, Choudhuri JV, Doss S, Elnakady YA, Frank B, Gaigalat L, Goesmann A, Groeger C, Gross F, Jelsbak L, Jelsbak L, Kalinowski J, Kegler C, Knauber T, Konietzny S, Kopp M, Krause L, Krug D, Linke B, Mahmud T, Martinez-Arias R, McHardy AC, Merai M, Meyer F, Mormann S, Muñoz-Dorado J, Perez J, Pradella S, Rachid S, Raddatz G, Rosenau F, Rückert C, Sasse F, Scharfe M, Schuster SC, Suen G, Treuner-Lange A, Velicer GJ, Vorhölter FJ, Weissman KJ, Welch RD, Wenzel SC, Whitworth DE, Wilhelm S, Wittmann C, Blöcker H, Pühler A, Müller R.

Nat Biotechnol. 2007 Nov;25(11):1281-9. Epub 2007 Oct 28.


Spatial organization of Myxococcus xanthus during fruiting body formation.

Curtis PD, Taylor RG, Welch RD, Shimkets LJ.

J Bacteriol. 2007 Dec;189(24):9126-30. Epub 2007 Oct 5.


Predicting prokaryotic ecological niches using genome sequence analysis.

Suen G, Goldman BS, Welch RD.

PLoS One. 2007 Aug 15;2(8):e743.


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