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Items: 23

1.

The role of protein complexes in human genetic disease.

Bergendahl LT, Gerasimavicius L, Miles J, Macdonald L, Wells JN, Welburn JPI, Marsh JA.

Protein Sci. 2019 Aug;28(8):1400-1411. doi: 10.1002/pro.3667. Epub 2019 Jul 1. Review.

PMID:
31219644
2.

Motors in transport and cytoskeleton remodeling.

Welburn JPI, Ostap EM.

Mol Biol Cell. 2019 Mar 15;30(6):734. doi: 10.1091/mbc.E19-01-0011. No abstract available.

3.

The depolymerase activity of MCAK shows a graded response to Aurora B kinase phosphorylation through allosteric regulation.

McHugh T, Zou J, Volkov VA, Bertin A, Talapatra SK, Rappsilber J, Dogterom M, Welburn JPI.

J Cell Sci. 2019 Jan 14;132(4). pii: jcs228353. doi: 10.1242/jcs.228353.

4.

A rapid computational approach identifies SPICE1 as an Aurora kinase substrate.

Deretic J, Kerr A, Welburn JPI.

Mol Biol Cell. 2019 Feb 1;30(3):312-323. doi: 10.1091/mbc.E18-08-0495. Epub 2018 Nov 28.

5.

Parts list for a microtubule depolymerising kinesin.

Friel CT, Welburn JP.

Biochem Soc Trans. 2018 Dec 17;46(6):1665-1672. doi: 10.1042/BST20180350. Epub 2018 Nov 22. Review.

6.

Microtubule end tethering of a processive kinesin-8 motor Kif18b is required for spindle positioning.

McHugh T, Gluszek AA, Welburn JPI.

J Cell Biol. 2018 Jul 2;217(7):2403-2416. doi: 10.1083/jcb.201705209. Epub 2018 Apr 16.

7.

Mechanisms of Mitotic Kinase Regulation: A Structural Perspective.

Welburn JPI, Jeyaprakash AA.

Front Cell Dev Biol. 2018 Feb 5;6:6. doi: 10.3389/fcell.2018.00006. eCollection 2018. Review.

8.

Dynein at kinetochores: Making the connection.

McHugh T, Welburn JP.

J Cell Biol. 2017 Apr 3;216(4):855-857. doi: 10.1083/jcb.201703054. Epub 2017 Mar 20.

9.

Inhibition of ectopic microtubule assembly by the kinesin-13 KLP-7 prevents chromosome segregation and cytokinesis defects in oocytes.

Gigant E, Stefanutti M, Laband K, Gluszek-Kustusz A, Edwards F, Lacroix B, Maton G, Canman JC, Welburn JPI, Dumont J.

Development. 2017 May 1;144(9):1674-1686. doi: 10.1242/dev.147504. Epub 2017 Mar 13.

10.

Molecular architecture of the Dam1 complex-microtubule interaction.

Legal T, Zou J, Sochaj A, Rappsilber J, Welburn JP.

Open Biol. 2016 Mar;6(3). pii: 150237. doi: 10.1098/rsob.150237.

11.

Aurora A Kinase Contributes to a Pole-Based Error Correction Pathway.

Ye AA, Deretic J, Hoel CM, Hinman AW, Cimini D, Welburn JP, Maresca TJ.

Curr Biol. 2015 Jul 20;25(14):1842-51. doi: 10.1016/j.cub.2015.06.021. Epub 2015 Jul 9.

12.
13.

Length-dependent anisotropic scaling of spindle shape.

Young S, Besson S, Welburn JP.

Biol Open. 2014 Nov 21;3(12):1217-23. doi: 10.1242/bio.201410363.

14.

The molecular basis for kinesin functional specificity during mitosis.

Welburn JP.

Cytoskeleton (Hoboken). 2013 Sep;70(9):476-93. doi: 10.1002/cm.21135. Epub 2013 Oct 8. Review.

15.

The microtubule-binding protein Cep170 promotes the targeting of the kinesin-13 depolymerase Kif2b to the mitotic spindle.

Welburn JP, Cheeseman IM.

Mol Biol Cell. 2012 Dec;23(24):4786-95. doi: 10.1091/mbc.E12-03-0214. Epub 2012 Oct 19.

16.

Aurora B phosphorylates spatially distinct targets to differentially regulate the kinetochore-microtubule interface.

Welburn JP, Vleugel M, Liu D, Yates JR 3rd, Lampson MA, Fukagawa T, Cheeseman IM.

Mol Cell. 2010 May 14;38(3):383-92. doi: 10.1016/j.molcel.2010.02.034.

17.

The human kinetochore Ska1 complex facilitates microtubule depolymerization-coupled motility.

Welburn JP, Grishchuk EL, Backer CB, Wilson-Kubalek EM, Yates JR 3rd, Cheeseman IM.

Dev Cell. 2009 Mar;16(3):374-85. doi: 10.1016/j.devcel.2009.01.011.

18.

CCAN makes multiple contacts with centromeric DNA to provide distinct pathways to the outer kinetochore.

Hori T, Amano M, Suzuki A, Backer CB, Welburn JP, Dong Y, McEwen BF, Shang WH, Suzuki E, Okawa K, Cheeseman IM, Fukagawa T.

Cell. 2008 Dec 12;135(6):1039-52. doi: 10.1016/j.cell.2008.10.019.

19.

Toward a molecular structure of the eukaryotic kinetochore.

Welburn JP, Cheeseman IM.

Dev Cell. 2008 Nov;15(5):645-55. doi: 10.1016/j.devcel.2008.10.011.

20.

Architecture of the Dam1 kinetochore ring complex and implications for microtubule-driven assembly and force-coupling mechanisms.

Wang HW, Ramey VH, Westermann S, Leschziner AE, Welburn JP, Nakajima Y, Drubin DG, Barnes G, Nogales E.

Nat Struct Mol Biol. 2007 Aug;14(8):721-6. Epub 2007 Jul 22.

PMID:
17643123
21.

How tyrosine 15 phosphorylation inhibits the activity of cyclin-dependent kinase 2-cyclin A.

Welburn JP, Tucker JA, Johnson T, Lindert L, Morgan M, Willis A, Noble ME, Endicott JA.

J Biol Chem. 2007 Feb 2;282(5):3173-81. Epub 2006 Nov 9.

22.

Molecular basis for the recognition of phosphorylated and phosphoacetylated histone h3 by 14-3-3.

Macdonald N, Welburn JP, Noble ME, Nguyen A, Yaffe MB, Clynes D, Moggs JG, Orphanides G, Thomson S, Edmunds JW, Clayton AL, Endicott JA, Mahadevan LC.

Mol Cell. 2005 Oct 28;20(2):199-211.

23.

Inhibition of the cell cycle with chemical inhibitors: a targeted approach.

Welburn JP, Endicott JA.

Semin Cell Dev Biol. 2005 Jun;16(3):369-81. Review.

PMID:
15840445

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