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Items: 1 to 50 of 113

1.

Reporting of serious adverse events during cancer clinical trials to the institutional review board: an evaluation by the research on adverse drug events and reports (RADAR) project.

Belknap SM, Georgopoulos CH, Lagman J, Weitzman SA, Qualkenbush L, Yarnold PR, Edwards BJ, McKoy JM, Trifilio SM, West DP.

J Clin Pharmacol. 2013 Dec;53(12):1334-40. doi: 10.1002/jcph.177. Epub 2013 Sep 25.

PMID:
24030903
2.

Chronic inflammation and cancer: the role of the mitochondria.

Kamp DW, Shacter E, Weitzman SA.

Oncology (Williston Park). 2011 Apr 30;25(5):400-10, 413. Review.

3.

Role of mitochondrial hOGG1 and aconitase in oxidant-induced lung epithelial cell apoptosis.

Panduri V, Liu G, Surapureddi S, Kondapalli J, Soberanes S, de Souza-Pinto NC, Bohr VA, Budinger GR, Schumacker PT, Weitzman SA, Kamp DW.

Free Radic Biol Med. 2009 Sep 15;47(6):750-9. doi: 10.1016/j.freeradbiomed.2009.06.010. Epub 2009 Jun 12.

4.

Quality of reporting of serious adverse drug events to an institutional review board: a case study with the novel cancer agent, imatinib mesylate.

Dorr DA, Burdon R, West DP, Lagman J, Georgopoulos C, Belknap SM, McKoy JM, Djulbegovic B, Edwards BJ, Weitzman SA, Boyle S, Tallman MS, Talpaz M, Sartor O, Bennett CL.

Clin Cancer Res. 2009 Jun 1;15(11):3850-5. doi: 10.1158/1078-0432.CCR-08-1811. Epub 2009 May 19.

5.

Evaluation of serious adverse drug reactions: a proactive pharmacovigilance program (RADAR) vs safety activities conducted by the Food and Drug Administration and pharmaceutical manufacturers.

Bennett CL, Nebeker JR, Yarnold PR, Tigue CC, Dorr DA, McKoy JM, Edwards BJ, Hurdle JF, West DP, Lau DT, Angelotta C, Weitzman SA, Belknap SM, Djulbegovic B, Tallman MS, Kuzel TM, Benson AB, Evens A, Trifilio SM, Courtney DM, Raisch DW.

Arch Intern Med. 2007 May 28;167(10):1041-9.

PMID:
17533207
6.

P53 mediates amosite asbestos-induced alveolar epithelial cell mitochondria-regulated apoptosis.

Panduri V, Surapureddi S, Soberanes S, Weitzman SA, Chandel N, Kamp DW.

Am J Respir Cell Mol Biol. 2006 Apr;34(4):443-52. Epub 2005 Dec 15.

7.
8.

Mitochondrial-derived free radicals mediate asbestos-induced alveolar epithelial cell apoptosis.

Panduri V, Weitzman SA, Chandel NS, Kamp DW.

Am J Physiol Lung Cell Mol Physiol. 2004 Jun;286(6):L1220-7. Epub 2004 Feb 6.

9.

The mitochondria-regulated death pathway mediates asbestos-induced alveolar epithelial cell apoptosis.

Panduri V, Weitzman SA, Chandel N, Kamp DW.

Am J Respir Cell Mol Biol. 2003 Feb;28(2):241-8.

PMID:
12540492
10.

Asbestos-induced alveolar epithelial cell apoptosis: role of mitochondrial dysfunction caused by iron-derived free radicals.

Kamp DW, Panduri Va, Weitzman SA, Chandel N.

Mol Cell Biochem. 2002 May-Jun;234-235(1-2):153-60.

PMID:
12162428
11.

Chronic inflammation and cancer.

Shacter E, Weitzman SA.

Oncology (Williston Park). 2002 Feb;16(2):217-26, 229; discussion 230-2. Review.

12.

Kruppel-like factor 4 regulates laminin alpha 3A expression in mammary epithelial cells.

Miller KA, Eklund EA, Peddinghaus ML, Cao Z, Fernandes N, Turk PW, Thimmapaya B, Weitzman SA.

J Biol Chem. 2001 Nov 16;276(46):42863-8. Epub 2001 Sep 10.

13.

Asbestos causes apoptosis in alveolar epithelial cells: role of iron-induced free radicals.

Aljandali A, Pollack H, Yeldandi A, Li Y, Weitzman SA, Kamp DW.

J Lab Clin Med. 2001 May;137(5):330-9.

PMID:
11329530
14.

Loss of cyclin D2 expression in the majority of breast cancers is associated with promoter hypermethylation.

Evron E, Umbricht CB, Korz D, Raman V, Loeb DM, Niranjan B, Buluwela L, Weitzman SA, Marks J, Sukumar S.

Cancer Res. 2001 Mar 15;61(6):2782-7.

15.

Wilms' tumor suppressor gene (WT1) is expressed in primary breast tumors despite tumor-specific promoter methylation.

Loeb DM, Evron E, Patel CB, Sharma PM, Niranjan B, Buluwela L, Weitzman SA, Korz D, Sukumar S.

Cancer Res. 2001 Feb 1;61(3):921-5.

16.

Cigarette smoke and asbestos activate poly-ADP-ribose polymerase in alveolar epithelial cells.

Kamp DW, Srinivasan M, Weitzman SA.

J Investig Med. 2001 Jan;49(1):68-76. doi: 10.2310/6650.2001.34092.

PMID:
11217149
17.

Breast cancer-specific expression of the Candida albicans cytosine deaminase gene using a transcriptional targeting approach.

Anderson LM, Krotz S, Weitzman SA, Thimmapaya B.

Cancer Gene Ther. 2000 Jun;7(6):845-52.

18.

Inhibition of laminin-5 production in breast epithelial cells by overexpression of p300.

Miller KA, Chung J, Lo D, Jones JC, Thimmapaya B, Weitzman SA.

J Biol Chem. 2000 Mar 17;275(11):8176-82.

19.

Regulation of expression of N-methylpurine DNA glycosylase in human mammary epithelial cells: role of transcription factor AP-2.

Cerda SR, Chu SS, Garcia P, Chung J, Grumet JD, Thimmapaya B, Weitzman SA.

Chem Res Toxicol. 1999 Nov;12(11):1098-109.

PMID:
10563836
20.

Adenovirus-mediated tissue-targeted expression of the HSVtk gene for the treatment of breast cancer.

Anderson LM, Swaminathan S, Zackon I, Tajuddin AK, Thimmapaya B, Weitzman SA.

Gene Ther. 1999 May;6(5):854-64.

21.

Cancer pain management through a pharmacist-based analgesic dosing service.

Lothian ST, Fotis MA, von Gunten CF, Lyons J, Von Roenn JH, Weitzman SA.

Am J Health Syst Pharm. 1999 Jun 1;56(11):1119-25. No abstract available.

PMID:
10385460
22.

The molecular basis of asbestos induced lung injury.

Kamp DW, Weitzman SA.

Thorax. 1999 Jul;54(7):638-52. Review. No abstract available.

23.

Cigarette smoke augments asbestos-induced alveolar epithelial cell injury: role of free radicals.

Kamp DW, Greenberger MJ, Sbalchierro JS, Preusen SE, Weitzman SA.

Free Radic Biol Med. 1998 Oct;25(6):728-39.

PMID:
9801074
24.

Altered expression of the DNA repair protein, N-methylpurine-DNA glycosylase (MPG) in breast cancer.

Cerda SR, Turk PW, Thor AD, Weitzman SA.

FEBS Lett. 1998 Jul 10;431(1):12-8.

25.

Mapping of ER gene CpG island methylation-specific polymerase chain reaction.

Lapidus RG, Nass SJ, Butash KA, Parl FF, Weitzman SA, Graff JG, Herman JG, Davidson NE.

Cancer Res. 1998 Jun 15;58(12):2515-9.

26.

Methylation of the HIC-1 candidate tumor suppressor gene in human breast cancer.

Fujii H, Biel MA, Zhou W, Weitzman SA, Baylin SB, Gabrielson E.

Oncogene. 1998 Apr 23;16(16):2159-64.

27.

Occasion sudden.

Weitzman SA.

Pharos Alpha Omega Alpha Honor Med Soc. 1998 Winter;61(1):13-5. No abstract available.

PMID:
9529919
28.

Influence of oxygen radical injury on DNA methylation.

Cerda S, Weitzman SA.

Mutat Res. 1997 Apr;386(2):141-52. Review.

PMID:
9113115
29.

Asbestosis: clinical spectrum and pathogenic mechanisms.

Kamp DW, Weitzman SA.

Proc Soc Exp Biol Med. 1997 Jan;214(1):12-26. Review.

PMID:
9012357
30.

Molecular typing for investigating an outbreak of Candida krusei.

Noskin GA, Lee J, Hacek DM, Postelnick M, Reisberg BE, Stosor V, Weitzman SA, Peterson LR.

Diagn Microbiol Infect Dis. 1996 Nov-Dec;26(3-4):117-23.

PMID:
9078446
31.

Methylation of estrogen and progesterone receptor gene 5' CpG islands correlates with lack of estrogen and progesterone receptor gene expression in breast tumors.

Lapidus RG, Ferguson AT, Ottaviano YL, Parl FF, Smith HS, Weitzman SA, Baylin SB, Issa JP, Davidson NE.

Clin Cancer Res. 1996 May;2(5):805-10.

32.

Mechanisms of carcinogenesis and clinical features of asbestos-associated cancers.

Mossman BT, Kamp DW, Weitzman SA.

Cancer Invest. 1996;14(5):466-80. Review.

PMID:
8816862
33.

Expression of hemidesmosomes and component proteins is lost by invasive breast cancer cells.

Bergstraesser LM, Srinivasan G, Jones JC, Stahl S, Weitzman SA.

Am J Pathol. 1995 Dec;147(6):1823-39.

34.

Phytic acid, an iron chelator, attenuates pulmonary inflammation and fibrosis in rats after intratracheal instillation of asbestos.

Kamp DW, Israbian VA, Yeldandi AV, Panos RJ, Graceffa P, Weitzman SA.

Toxicol Pathol. 1995 Nov-Dec;23(6):689-95.

PMID:
8772254
35.
36.

DNA adduct 8-hydroxyl-2'-deoxyguanosine (8-hydroxyguanine) affects function of human DNA methyltransferase.

Turk PW, Laayoun A, Smith SS, Weitzman SA.

Carcinogenesis. 1995 May;16(5):1253-5.

PMID:
7767994
37.

Sequential changes in serum iron and ferritin in patients undergoing high-dose chemotherapy and radiation with autologous bone marrow transplantation: possible implications for treatment related toxicity.

Gordon LI, Brown SG, Tallman MS, Rademaker AW, Weitzman SA, Lazarus HM, Kelley CH, Mangan C, Rubin H, Fox RM, et al.

Free Radic Biol Med. 1995 Mar;18(3):383-9.

PMID:
9101228
38.

Asbestos causes DNA strand breaks in cultured pulmonary epithelial cells: role of iron-catalyzed free radicals.

Kamp DW, Israbian VA, Preusen SE, Zhang CX, Weitzman SA.

Am J Physiol. 1995 Mar;268(3 Pt 1):L471-80.

PMID:
7900829
39.

Dibutyryl cAMP attenuates asbestos-induced pulmonary epithelial cell cytotoxicity and decline in ATP levels.

Israbian VA, Weitzman SA, Kamp DW.

Am J Physiol. 1994 Nov;267(5 Pt 1):L518-25.

PMID:
7977762
40.

Megestrol acetate in patients with AIDS-related cachexia.

Von Roenn JH, Armstrong D, Kotler DP, Cohn DL, Klimas NG, Tchekmedyian NS, Cone L, Brennan PJ, Weitzman SA.

Ann Intern Med. 1994 Sep 15;121(6):393-9.

PMID:
7794302
41.

Free radical adducts induce alterations in DNA cytosine methylation.

Weitzman SA, Turk PW, Milkowski DH, Kozlowski K.

Proc Natl Acad Sci U S A. 1994 Feb 15;91(4):1261-4.

42.

Contrasting effects of alveolar macrophages and neutrophils on asbestos-induced pulmonary epithelial cell injury.

Kamp DW, Dunn MM, Sbalchiero JS, Knap AM, Weitzman SA.

Am J Physiol. 1994 Jan;266(1 Pt 1):L84-91.

PMID:
8304471
44.

Asbestos-induced injury to cultured human pulmonary epithelial-like cells: role of neutrophil elastase.

Kamp DW, Dunne M, Dykewicz MS, Sbalchiero JS, Weitzman SA, Dunn MM.

J Leukoc Biol. 1993 Jul;54(1):73-80.

PMID:
8336081
46.

Methylation inhibits the interaction of DNA binding proteins with a potential c-abl intron regulatory element.

Hengst-Zhang JA, Weitzman SA.

Biochem Biophys Res Commun. 1992 Aug 14;186(3):1515-21.

PMID:
1510678
47.

The role of free radicals in asbestos-induced diseases.

Kamp DW, Graceffa P, Pryor WA, Weitzman SA.

Free Radic Biol Med. 1992;12(4):293-315. Review.

PMID:
1577332
48.

Detection of differentiation in acute promyelocytic leukemia.

Tallman MS, Kwaan HC, Weitzman SA.

Blood. 1991 Oct 1;78(7):1892-3. No abstract available.

49.

AIDS and hospice.

von Gunten CF, Martinez J, Weitzman SA, Von Roenn J.

Am J Hosp Palliat Care. 1991 Jul-Aug;8(4):17-9.

PMID:
1931326
50.

Phase II trial of pentostatin in refractory lymphomas and cutaneous T-cell disease.

Cummings FJ, Kim K, Neiman RS, Comis RL, Oken MM, Weitzman SA, Mann RB, O'Connell MJ.

J Clin Oncol. 1991 Apr;9(4):565-71.

PMID:
2066753

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