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Items: 1 to 50 of 875

1.

Recording the wild lives of immune cells.

Pittet MJ, Garris CS, Arlauckas SP, Weissleder R.

Sci Immunol. 2018 Sep 7;3(27). pii: eaaq0491. doi: 10.1126/sciimmunol.aaq0491. Review.

PMID:
30194240
2.

Unsupervised Medical Image Segmentation Based on the Local Center of Mass.

Aganj I, Harisinghani MG, Weissleder R, Fischl B.

Sci Rep. 2018 Aug 29;8(1):13012. doi: 10.1038/s41598-018-31333-5.

3.

Direct vascular channels connect skull bone marrow and the brain surface enabling myeloid cell migration.

Herisson F, Frodermann V, Courties G, Rohde D, Sun Y, Vandoorne K, Wojtkiewicz GR, Masson GS, Vinegoni C, Kim J, Kim DE, Weissleder R, Swirski FK, Moskowitz MA, Nahrendorf M.

Nat Neurosci. 2018 Sep;21(9):1209-1217. doi: 10.1038/s41593-018-0213-2. Epub 2018 Aug 27.

PMID:
30150661
4.

Computational Optics Enables Breast Cancer Profiling in Point-of-Care Settings.

Min J, Im H, Allen M, McFarland PJ, Degani I, Yu H, Normandin E, Pathania D, Patel JM, Castro CM, Weissleder R, Lee H.

ACS Nano. 2018 Aug 20. doi: 10.1021/acsnano.8b03029. [Epub ahead of print]

PMID:
30113824
5.

Imaging the Vascular Bone Marrow Niche During Inflammatory Stress.

Vandoorne K, Rohde D, Kim HY, Courties G, Wojtkiewicz GR, Honold L, Hoyer FF, Frodermann V, Nayar R, Herisson FE, Jung Y, Désogère P, Vinegoni C, Caravan P, Weissleder R, Sosnovik DE, Lin CP, Swirski FK, Nahrendorf M.

Circ Res. 2018 Jul 6. pii: CIRCRESAHA.118.313302. doi: 10.1161/CIRCRESAHA.118.313302. [Epub ahead of print]

PMID:
29980569
6.

Development of third generation anti-EGFRvIII chimeric T cells and EGFRvIII-expressing artificial antigen presenting cells for adoptive cell therapy for glioma.

Sahin A, Sanchez C, Bullain S, Waterman P, Weissleder R, Carter BS.

PLoS One. 2018 Jul 5;13(7):e0199414. doi: 10.1371/journal.pone.0199414. eCollection 2018.

7.

Developing a Roadmap for Interventional Oncology.

Schoenberg SO, Attenberger UI, Solomon SB, Weissleder R.

Oncologist. 2018 Jun 29. pii: theoncologist.2017-0654. doi: 10.1634/theoncologist.2017-0654. [Epub ahead of print]

PMID:
29959284
8.

Analyses of Intravesicular Exosomal Proteins Using a Nano-Plasmonic System.

Park J, Im H, Hong S, Castro CM, Weissleder R, Lee H.

ACS Photonics. 2018 Feb 21;5(2):487-494. doi: 10.1021/acsphotonics.7b00992. Epub 2017 Nov 3.

PMID:
29805987
9.

Anti-CTLA-4 therapy requires an Fc domain for efficacy.

Ingram JR, Blomberg OS, Rashidian M, Ali L, Garforth S, Fedorov E, Fedorov AA, Bonanno JB, Le Gall C, Crowley S, Espinosa C, Biary T, Keliher EJ, Weissleder R, Almo SC, Dougan SK, Ploegh HL, Dougan M.

Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):3912-3917. doi: 10.1073/pnas.1801524115. Epub 2018 Mar 26.

10.

Integrated Biosensor for Rapid and Point-of-Care Sepsis Diagnosis.

Min J, Nothing M, Coble B, Zheng H, Park J, Im H, Weber GF, Castro CM, Swirski FK, Weissleder R, Lee H.

ACS Nano. 2018 Apr 24;12(4):3378-3384. doi: 10.1021/acsnano.7b08965. Epub 2018 Mar 20.

11.

Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles.

Ricklefs FL, Alayo Q, Krenzlin H, Mahmoud AB, Speranza MC, Nakashima H, Hayes JL, Lee K, Balaj L, Passaro C, Rooj AK, Krasemann S, Carter BS, Chen CC, Steed T, Treiber J, Rodig S, Yang K, Nakano I, Lee H, Weissleder R, Breakefield XO, Godlewski J, Westphal M, Lamszus K, Freeman GJ, Bronisz A, Lawler SE, Chiocca EA.

Sci Adv. 2018 Mar 7;4(3):eaar2766. doi: 10.1126/sciadv.aar2766. eCollection 2018 Mar.

12.

Fluorescence anisotropy imaging in drug discovery.

Vinegoni C, Feruglio PF, Gryczynski I, Mazitschek R, Weissleder R.

Adv Drug Deliv Rev. 2018 Feb 2. pii: S0169-409X(18)30027-9. doi: 10.1016/j.addr.2018.01.019. [Epub ahead of print]

PMID:
29410158
13.

Unraveling Tetrazine-Triggered Bioorthogonal Elimination Enables Chemical Tools for Ultrafast Release and Universal Cleavage.

Carlson JCT, Mikula H, Weissleder R.

J Am Chem Soc. 2018 Mar 14;140(10):3603-3612. doi: 10.1021/jacs.7b11217. Epub 2018 Feb 14.

14.

New Technologies for Analysis of Extracellular Vesicles.

Shao H, Im H, Castro CM, Breakefield X, Weissleder R, Lee H.

Chem Rev. 2018 Feb 28;118(4):1917-1950. doi: 10.1021/acs.chemrev.7b00534. Epub 2018 Jan 31.

15.

Cardiac macrophages promote diastolic dysfunction.

Hulsmans M, Sager HB, Roh JD, Valero-Muñoz M, Houstis NE, Iwamoto Y, Sun Y, Wilson RM, Wojtkiewicz G, Tricot B, Osborne MT, Hung J, Vinegoni C, Naxerova K, Sosnovik DE, Zile MR, Bradshaw AD, Liao R, Tawakol A, Weissleder R, Rosenzweig A, Swirski FK, Sam F, Nahrendorf M.

J Exp Med. 2018 Feb 5;215(2):423-440. doi: 10.1084/jem.20171274. Epub 2018 Jan 16.

16.

Multiplexed Profiling of Single Extracellular Vesicles.

Lee K, Fraser K, Ghaddar B, Yang K, Kim E, Balaj L, Chiocca EA, Breakefield XO, Lee H, Weissleder R.

ACS Nano. 2018 Jan 23;12(1):494-503. doi: 10.1021/acsnano.7b07060. Epub 2018 Jan 4.

17.

Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils.

Engblom C, Pfirschke C, Zilionis R, Da Silva Martins J, Bos SA, Courties G, Rickelt S, Severe N, Baryawno N, Faget J, Savova V, Zemmour D, Kline J, Siwicki M, Garris C, Pucci F, Liao HW, Lin YJ, Newton A, Yaghi OK, Iwamoto Y, Tricot B, Wojtkiewicz GR, Nahrendorf M, Cortez-Retamozo V, Meylan E, Hynes RO, Demay M, Klein A, Bredella MA, Scadden DT, Weissleder R, Pittet MJ.

Science. 2017 Dec 1;358(6367). pii: eaal5081. doi: 10.1126/science.aal5081.

PMID:
29191879
18.

Near infrared imaging of Mer tyrosine kinase (MERTK) using MERi-SiR reveals tumor associated macrophage uptake in metastatic disease.

Miller MA, Kim E, Cuccarese MF, Plotkin AL, Prytyskach M, Kohler RH, Pittet MJ, Weissleder R.

Chem Commun (Camb). 2017 Dec 19;54(1):42-45. doi: 10.1039/c7cc07581b.

PMID:
29185561
19.

Nanomagnetic System for Rapid Diagnosis of Acute Infection.

Park KS, Kim H, Kim S, Lee K, Park S, Song J, Min C, Khanam F, Rashu R, Bhuiyan TR, Ryan ET, Qadri F, Weissleder R, Cheon J, Charles RC, Lee H.

ACS Nano. 2017 Nov 28;11(11):11425-11432. doi: 10.1021/acsnano.7b06074. Epub 2017 Nov 14.

PMID:
29121461
20.

IRF3 and type I interferons fuel a fatal response to myocardial infarction.

King KR, Aguirre AD, Ye YX, Sun Y, Roh JD, Ng RP Jr, Kohler RH, Arlauckas SP, Iwamoto Y, Savol A, Sadreyev RI, Kelly M, Fitzgibbons TP, Fitzgerald KA, Mitchison T, Libby P, Nahrendorf M, Weissleder R.

Nat Med. 2017 Dec;23(12):1481-1487. doi: 10.1038/nm.4428. Epub 2017 Nov 6.

PMID:
29106401
21.

Prediction of Anti-cancer Nanotherapy Efficacy by Imaging.

Miller MA, Arlauckas S, Weissleder R.

Nanotheranostics. 2017 Jul 6;1(3):296-312. doi: 10.7150/ntno.20564. eCollection 2017. Review.

22.

Integrated microHall magnetometer to measure the magnetic properties of nanoparticles.

Min C, Park J, Mun JK, Lim Y, Min J, Lim JW, Kang DM, Ahn HK, Shin TH, Cheon J, Lee HS, Weissleder R, Castro CM, Lee H.

Lab Chip. 2017 Nov 21;17(23):4000-4007. doi: 10.1039/c7lc00934h.

PMID:
29067383
23.

Integrated Kidney Exosome Analysis for the Detection of Kidney Transplant Rejection.

Park J, Lin HY, Assaker JP, Jeong S, Huang CH, Kurdi T, Lee K, Fraser K, Min C, Eskandari S, Routray S, Tannous B, Abdi R, Riella L, Chandraker A, Castro CM, Weissleder R, Lee H, Azzi JR.

ACS Nano. 2017 Nov 28;11(11):11041-11046. doi: 10.1021/acsnano.7b05083. Epub 2017 Oct 25.

PMID:
29053921
24.

Preclinical investigation of combined gene-mediated cytotoxic immunotherapy and immune checkpoint blockade in glioblastoma.

Speranza MC, Passaro C, Ricklefs F, Kasai K, Klein SR, Nakashima H, Kaufmann JK, Ahmed AK, Nowicki MO, Obi P, Bronisz A, Aguilar-Cordova E, Aguilar LK, Guzik BW, Breakefield X, Weissleder R, Freeman GJ, Reardon DA, Wen PY, Chiocca EA, Lawler SE.

Neuro Oncol. 2018 Jan 22;20(2):225-235. doi: 10.1093/neuonc/nox139.

PMID:
29016938
25.

The infarcted myocardium solicits GM-CSF for the detrimental oversupply of inflammatory leukocytes.

Anzai A, Choi JL, He S, Fenn AM, Nairz M, Rattik S, McAlpine CS, Mindur JE, Chan CT, Iwamoto Y, Tricot B, Wojtkiewicz GR, Weissleder R, Libby P, Nahrendorf M, Stone JR, Becher B, Swirski FK.

J Exp Med. 2017 Nov 6;214(11):3293-3310. doi: 10.1084/jem.20170689. Epub 2017 Oct 4.

26.

PD-L1 is an activation-independent marker of brown adipocytes.

Ingram JR, Dougan M, Rashidian M, Knoll M, Keliher EJ, Garrett S, Garforth S, Blomberg OS, Espinosa C, Bhan A, Almo SC, Weissleder R, Lodish H, Dougan SK, Ploegh HL.

Nat Commun. 2017 Sep 21;8(1):647. doi: 10.1038/s41467-017-00799-8.

27.

Imaging the emergence and natural progression of spontaneous autoimmune diabetes.

Mohan JF, Kohler RH, Hill JA, Weissleder R, Mathis D, Benoist C.

Proc Natl Acad Sci U S A. 2017 Sep 12;114(37):E7776-E7785. doi: 10.1073/pnas.1707381114. Epub 2017 Aug 24.

28.

Integrated Magneto-Chemical Sensor For On-Site Food Allergen Detection.

Lin HY, Huang CH, Park J, Pathania D, Castro CM, Fasano A, Weissleder R, Lee H.

ACS Nano. 2017 Oct 24;11(10):10062-10069. doi: 10.1021/acsnano.7b04318. Epub 2017 Aug 25.

PMID:
28792732
29.

Novel nanosensing technologies for exosome detection and profiling.

Im H, Lee K, Weissleder R, Lee H, Castro CM.

Lab Chip. 2017 Aug 22;17(17):2892-2898. doi: 10.1039/c7lc00247e. Review.

30.

Deletion of β1-integrin in collecting duct principal cells leads to tubular injury and renal medullary fibrosis.

Mamuya FA, Xie D, Lei L, Huang M, Tsuji K, Capen DE, Yang B, Weissleder R, Păunescu TG, Lu HAJ.

Am J Physiol Renal Physiol. 2017 Oct 1;313(4):F1026-F1037. doi: 10.1152/ajprenal.00038.2017. Epub 2017 Jul 12.

PMID:
28701310
31.

Nano-palladium is a cellular catalyst for in vivo chemistry.

Miller MA, Askevold B, Mikula H, Kohler RH, Pirovich D, Weissleder R.

Nat Commun. 2017 Jul 12;8:15906. doi: 10.1038/ncomms15906.

32.

Measurement of drug-target engagement in live cells by two-photon fluorescence anisotropy imaging.

Vinegoni C, Fumene Feruglio P, Brand C, Lee S, Nibbs AE, Stapleton S, Shah S, Gryczynski I, Reiner T, Mazitschek R, Weissleder R.

Nat Protoc. 2017 Jul;12(7):1472-1497. doi: 10.1038/nprot.2017.043. Epub 2017 Jun 29.

33.

Imaging of anticancer drug action in single cells.

Miller MA, Weissleder R.

Nat Rev Cancer. 2017 Jun 23;17(7):399-414. doi: 10.1038/nrc.2017.41. Review.

PMID:
28642603
34.

Real-time quantitative analysis of metabolic flux in live cells using a hyperpolarized micromagnetic resonance spectrometer.

Jeong S, Eskandari R, Park SM, Alvarez J, Tee SS, Weissleder R, Kharas MG, Lee H, Keshari KR.

Sci Adv. 2017 Jun 16;3(6):e1700341. doi: 10.1126/sciadv.1700341. eCollection 2017 Jun.

35.

Radiation therapy primes tumors for nanotherapeutic delivery via macrophage-mediated vascular bursts.

Miller MA, Chandra R, Cuccarese MF, Pfirschke C, Engblom C, Stapleton S, Adhikary U, Kohler RH, Mohan JF, Pittet MJ, Weissleder R.

Sci Transl Med. 2017 May 31;9(392). pii: eaal0225. doi: 10.1126/scitranslmed.aal0225.

PMID:
28566423
36.

Multiparametric plasma EV profiling facilitates diagnosis of pancreatic malignancy.

Yang KS, Im H, Hong S, Pergolini I, Del Castillo AF, Wang R, Clardy S, Huang CH, Pille C, Ferrone S, Yang R, Castro CM, Lee H, Del Castillo CF, Weissleder R.

Sci Transl Med. 2017 May 24;9(391). pii: eaal3226. doi: 10.1126/scitranslmed.aal3226.

37.

MicroRNA Signatures and Molecular Subtypes of Glioblastoma: The Role of Extracellular Transfer.

Godlewski J, Ferrer-Luna R, Rooj AK, Mineo M, Ricklefs F, Takeda YS, Nowicki MO, Salińska E, Nakano I, Lee H, Weissleder R, Beroukhim R, Chiocca EA, Bronisz A.

Stem Cell Reports. 2017 Jun 6;8(6):1497-1505. doi: 10.1016/j.stemcr.2017.04.024. Epub 2017 May 18.

38.

In vivo imaging reveals a tumor-associated macrophage-mediated resistance pathway in anti-PD-1 therapy.

Arlauckas SP, Garris CS, Kohler RH, Kitaoka M, Cuccarese MF, Yang KS, Miller MA, Carlson JC, Freeman GJ, Anthony RM, Weissleder R, Pittet MJ.

Sci Transl Med. 2017 May 10;9(389). pii: eaal3604. doi: 10.1126/scitranslmed.aal3604.

39.

Design and Development of Fluorescent Vemurafenib Analogs for In Vivo Imaging.

Mikula H, Stapleton S, Kohler RH, Vinegoni C, Weissleder R.

Theranostics. 2017 Mar 6;7(5):1257-1265. doi: 10.7150/thno.18238. eCollection 2017.

40.

Macrophages Facilitate Electrical Conduction in the Heart.

Hulsmans M, Clauss S, Xiao L, Aguirre AD, King KR, Hanley A, Hucker WJ, Wülfers EM, Seemann G, Courties G, Iwamoto Y, Sun Y, Savol AJ, Sager HB, Lavine KJ, Fishbein GA, Capen DE, Da Silva N, Miquerol L, Wakimoto H, Seidman CE, Seidman JG, Sadreyev RI, Naxerova K, Mitchell RN, Brown D, Libby P, Weissleder R, Swirski FK, Kohl P, Vinegoni C, Milan DJ, Ellinor PT, Nahrendorf M.

Cell. 2017 Apr 20;169(3):510-522.e20. doi: 10.1016/j.cell.2017.03.050.

41.

Transparent Electrophysiology Microelectrodes and Interconnects from Metal Nanomesh.

Seo KJ, Qiang Y, Bilgin I, Kar S, Vinegoni C, Weissleder R, Fang H.

ACS Nano. 2017 Apr 25;11(4):4365-4372. doi: 10.1021/acsnano.7b01995. Epub 2017 Apr 11.

PMID:
28391679
42.

Motion characterization scheme to minimize motion artifacts in intravital microscopy.

Lee S, Courties G, Nahrendorf M, Weissleder R, Vinegoni C.

J Biomed Opt. 2017 Mar 1;22(3):36005. doi: 10.1117/1.JBO.22.3.036005.

43.

Heterogeneity of macrophage infiltration and therapeutic response in lung carcinoma revealed by 3D organ imaging.

Cuccarese MF, Dubach JM, Pfirschke C, Engblom C, Garris C, Miller MA, Pittet MJ, Weissleder R.

Nat Commun. 2017 Feb 8;8:14293. doi: 10.1038/ncomms14293.

44.

Facile silicification of plastic surface for bioassays.

Hong S, Park KS, Weissleder R, Castro CM, Lee H.

Chem Commun (Camb). 2017 Feb 9;53(13):2134-2137. doi: 10.1039/c6cc09359k.

45.

Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischaemic heart disease.

Keliher EJ, Ye YX, Wojtkiewicz GR, Aguirre AD, Tricot B, Senders ML, Groenen H, Fay F, Perez-Medina C, Calcagno C, Carlucci G, Reiner T, Sun Y, Courties G, Iwamoto Y, Kim HY, Wang C, Chen JW, Swirski FK, Wey HY, Hooker J, Fayad ZA, Mulder WJ, Weissleder R, Nahrendorf M.

Nat Commun. 2017 Jan 16;8:14064. doi: 10.1038/ncomms14064.

46.

Point of care assessment of melanoma tumor signaling and metastatic burden from μNMR analysis of tumor fine needle aspirates and peripheral blood.

Gee MS, Ghazani AA, Haq R, Wargo JA, Sebas M, Sullivan RJ, Lee H, Weissleder R.

Nanomedicine. 2017 Apr;13(3):821-828. doi: 10.1016/j.nano.2016.12.006. Epub 2016 Dec 18.

47.

Quantitating drug-target engagement in single cells in vitro and in vivo.

Dubach JM, Kim E, Yang K, Cuccarese M, Giedt RJ, Meimetis LG, Vinegoni C, Weissleder R.

Nat Chem Biol. 2017 Feb;13(2):168-173. doi: 10.1038/nchembio.2248. Epub 2016 Dec 5.

48.

PF4 Promotes Platelet Production and Lung Cancer Growth.

Pucci F, Rickelt S, Newton AP, Garris C, Nunes E, Evavold C, Pfirschke C, Engblom C, Mino-Kenudson M, Hynes RO, Weissleder R, Pittet MJ.

Cell Rep. 2016 Nov 8;17(7):1764-1772. doi: 10.1016/j.celrep.2016.10.031.

49.

Facile Coating Strategy to Functionalize Inorganic Nanoparticles for Biosensing.

Park YI, Kim E, Huang CH, Park KS, Castro CM, Lee H, Weissleder R.

Bioconjug Chem. 2017 Jan 18;28(1):33-37. doi: 10.1021/acs.bioconjchem.6b00524. Epub 2016 Nov 7.

50.

Computational imaging reveals mitochondrial morphology as a biomarker of cancer phenotype and drug response.

Giedt RJ, Fumene Feruglio P, Pathania D, Yang KS, Kilcoyne A, Vinegoni C, Mitchison TJ, Weissleder R.

Sci Rep. 2016 Sep 9;6:32985. doi: 10.1038/srep32985.

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