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Items: 40

1.

Variants That Affect Function of Calcium Channel TRPV6 Are Associated With Early-onset Chronic Pancreatitis: TRPV6 and pancreatitis.

Masamune A, Kotani H, Sörgel FL, Chen JM, Hamada S, Sakaguchi R, Masson E, Nakano E, Kakuta Y, Niihori T, Funayama R, Shirota M, Hirano T, Kawamoto T, Hosokoshi A, Kume K, Unger L, Ewers M, Laumen H, Bugert P, Mori MX, Tsvilovskyy V, Weißgerber P, Kriebs U, Fecher-Trost C, Freichel M, Diakopoulos KN, Berninger A, Lesina M, Ishii K, Itoi T, Ikeura T, Okazaki K, Kaune T, Rosendahl J, Nagasaki M, Uezono Y, Algül H, Nakayama K, Matsubara Y, Aoki Y, Férec C, Mori Y, Witt H, Shimosegawa T.

Gastroenterology. 2020 Jan 10. pii: S0016-5085(20)30017-2. doi: 10.1053/j.gastro.2020.01.005. [Epub ahead of print]

PMID:
31930989
2.

TRPC channels regulate Ca2+-signaling and short-term plasticity of fast glutamatergic synapses.

Schwarz Y, Oleinikov K, Schindeldecker B, Wyatt A, Weißgerber P, Flockerzi V, Boehm U, Freichel M, Bruns D.

PLoS Biol. 2019 Sep 19;17(9):e3000445. doi: 10.1371/journal.pbio.3000445. eCollection 2019 Sep.

3.

TRPV6 and Cav1.3 Mediate Distal Small Intestine Calcium Absorption Before Weaning.

Beggs MR, Lee JJ, Busch K, Raza A, Dimke H, Weissgerber P, Engel J, Flockerzi V, Alexander RT.

Cell Mol Gastroenterol Hepatol. 2019;8(4):625-642. doi: 10.1016/j.jcmgh.2019.07.005. Epub 2019 Aug 6.

4.

Trpc5 deficiency causes hypoprolactinemia and altered function of oscillatory dopamine neurons in the arcuate nucleus.

Blum T, Moreno-Pérez A, Pyrski M, Bufe B, Arifovic A, Weissgerber P, Freichel M, Zufall F, Leinders-Zufall T.

Proc Natl Acad Sci U S A. 2019 Jul 23;116(30):15236-15243. doi: 10.1073/pnas.1905705116. Epub 2019 Jul 8.

5.

The Evolution of Erythrocytes Becoming Red in Respect to Fluorescence.

Hertz L, Ruppenthal S, Simionato G, Quint S, Kihm A, Abay A, Petkova-Kirova P, Boehm U, Weissgerber P, Wagner C, Laschke MW, Kaestner L.

Front Physiol. 2019 Jun 19;10:753. doi: 10.3389/fphys.2019.00753. eCollection 2019.

6.

Activation of the calcium sensing receptor attenuates TRPV6-dependent intestinal calcium absorption.

Lee JJ, Liu X, O'Neill D, Beggs MR, Weissgerber P, Flockerzi V, Chen XZ, Dimke H, Alexander RT.

JCI Insight. 2019 Apr 23;5. pii: 128013. doi: 10.1172/jci.insight.128013.

7.

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

Fecher-Trost C, Lux F, Busch KM, Raza A, Winter M, Hielscher F, Belkacemi T, van der Eerden B, Boehm U, Freichel M, Weissgerber P.

J Bone Miner Res. 2019 Apr;34(4):699-710. doi: 10.1002/jbmr.3646. Epub 2019 Feb 20.

PMID:
30786075
8.

Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory.

Bröker-Lai J, Kollewe A, Schindeldecker B, Pohle J, Nguyen Chi V, Mathar I, Guzman R, Schwarz Y, Lai A, Weißgerber P, Schwegler H, Dietrich A, Both M, Sprengel R, Draguhn A, Köhr G, Fakler B, Flockerzi V, Bruns D, Freichel M.

EMBO J. 2017 Sep 15;36(18):2770-2789. doi: 10.15252/embj.201696369. Epub 2017 Aug 8.

9.

TRPC1- and TRPC3-dependent Ca2+ signaling in mouse cortical astrocytes affects injury-evoked astrogliosis in vivo.

Belkacemi T, Niermann A, Hofmann L, Wissenbach U, Birnbaumer L, Leidinger P, Backes C, Meese E, Keller A, Bai X, Scheller A, Kirchhoff F, Philipp SE, Weissgerber P, Flockerzi V, Beck A.

Glia. 2017 Sep;65(9):1535-1549. doi: 10.1002/glia.23180. Epub 2017 Jun 21.

10.

TRPV6: From identification to function.

Fecher-Trost C, Wissenbach U, Weissgerber P.

Cell Calcium. 2017 Nov;67:116-122. doi: 10.1016/j.ceca.2017.04.006. Epub 2017 Apr 28. Review. No abstract available.

PMID:
28501141
11.

Functional Characterization of Transient Receptor Potential (TRP) Channel C5 in Female Murine Gonadotropes.

Beck A, Götz V, Qiao S, Weissgerber P, Flockerzi V, Freichel M, Boehm U.

Endocrinology. 2017 Apr 1;158(4):887-902. doi: 10.1210/en.2016-1810.

PMID:
28324107
12.

Murine Autoimmune Optic Neuritis Is Not Phenotypically Altered by the Retinal Degeneration 8 Mutation.

Stojic A, Fairless R, Beck SC, Sothilingam V, Weissgerber P, Wissenbach U, Gimmy V, Seeliger MW, Flockerzi V, Diem R, Williams SK.

Invest Ophthalmol Vis Sci. 2017 Jan 1;58(1):318-328. doi: 10.1167/iovs.16-20419.

PMID:
28114593
13.

Essential roles for Cavβ2 and Cav1 channels in thymocyte development and T cell homeostasis.

Jha A, Singh AK, Weissgerber P, Freichel M, Flockerzi V, Flavell RA, Jha MK.

Sci Signal. 2015 Oct 20;8(399):ra103. doi: 10.1126/scisignal.aac7538.

PMID:
26486172
14.

Influence of the β2-Subunit of L-Type Voltage-Gated Cav Channels on the Structural and Functional Development of Photoreceptor Ribbon Synapses.

Katiyar R, Weissgerber P, Roth E, Dörr J, Sothilingam V, Garcia Garrido M, Beck SC, Seeliger MW, Beck A, Schmitz F, Flockerzi V.

Invest Ophthalmol Vis Sci. 2015 Apr;56(4):2312-24. doi: 10.1167/iovs.15-16654.

PMID:
25766584
15.

Altered synaptic transmission at olfactory and vomeronasal nerve terminals in mice lacking N-type calcium channel Cav2.2.

Weiss J, Pyrski M, Weissgerber P, Zufall F.

Eur J Neurosci. 2014 Nov;40(10):3422-35. doi: 10.1111/ejn.12713. Epub 2014 Sep 5.

PMID:
25195871
16.

TRPV6 channels.

Fecher-Trost C, Weissgerber P, Wissenbach U.

Handb Exp Pharmacol. 2014;222:359-84. doi: 10.1007/978-3-642-54215-2_14. Review.

PMID:
24756713
17.

Functional TRPV6 channels are crucial for transepithelial Ca2+ absorption.

Woudenberg-Vrenken TE, Lameris AL, Weißgerber P, Olausson J, Flockerzi V, Bindels RJ, Freichel M, Hoenderop JG.

Am J Physiol Gastrointest Liver Physiol. 2012 Oct;303(7):G879-85. doi: 10.1152/ajpgi.00089.2012. Epub 2012 Aug 9.

18.

In vitro activity of tigecycline and molecular characterization of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates from a university hospital in south-western Germany.

Wienke M, Pfeifer Y, Weissgerber P, Marschal M, Autenrieth IB, Gröbner S.

Chemotherapy. 2012;58(3):241-8. doi: 10.1159/000339488. Epub 2012 Jul 25.

PMID:
22832033
19.

Strategies and Protocols to Generate Mouse Models with Targeted Mutations to Analyze TRP Channel Functions.

Freichel M, Kriebs U, Vogt D, Mannebach S, Weißgerber P.

In: Zhu MX, editor. TRP Channels. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. Chapter 8.

20.

Excision of Trpv6 gene leads to severe defects in epididymal Ca2+ absorption and male fertility much like single D541A pore mutation.

Weissgerber P, Kriebs U, Tsvilovskyy V, Olausson J, Kretz O, Stoerger C, Mannebach S, Wissenbach U, Vennekens R, Middendorff R, Flockerzi V, Freichel M.

J Biol Chem. 2012 May 25;287(22):17930-41. doi: 10.1074/jbc.M111.328286. Epub 2012 Mar 15.

21.

Melanopsin signalling in mammalian iris and retina.

Xue T, Do MT, Riccio A, Jiang Z, Hsieh J, Wang HC, Merbs SL, Welsbie DS, Yoshioka T, Weissgerber P, Stolz S, Flockerzi V, Freichel M, Simon MI, Clapham DE, Yau KW.

Nature. 2011 Nov 2;479(7371):67-73. doi: 10.1038/nature10567.

22.

The transient receptor potential channel TRPV6 is dynamically expressed in bone cells but is not crucial for bone mineralization in mice.

van der Eerden BC, Weissgerber P, Fratzl-Zelman N, Olausson J, Hoenderop JG, Schreuders-Koedam M, Eijken M, Roschger P, de Vries TJ, Chiba H, Klaushofer K, Flockerzi V, Bindels RJ, Freichel M, van Leeuwen JP.

J Cell Physiol. 2012 May;227(5):1951-9. doi: 10.1002/jcp.22923.

PMID:
21732366
23.

Male fertility depends on Ca²+ absorption by TRPV6 in epididymal epithelia.

Weissgerber P, Kriebs U, Tsvilovskyy V, Olausson J, Kretz O, Stoerger C, Vennekens R, Wissenbach U, Middendorff R, Flockerzi V, Freichel M.

Sci Signal. 2011 May 3;4(171):ra27. doi: 10.1126/scisignal.2001791.

24.

Accuracy of serum LDH elevation for the diagnosis of Pneumocystis jiroveci pneumonia.

Vogel M, Weissgerber P, Goeppert B, Hetzel J, Vatlach M, Claussen C, Horger M.

Swiss Med Wkly. 2011 Apr 29;141:w13184. doi: 10.4414/smw.2011.13184. eCollection 2011.

25.

HRCT-features of Pneumocystis jiroveci pneumonia and their evolution before and after treatment in non-HIV immunocompromised patients.

Vogel MN, Vatlach M, Weissgerber P, Goeppert B, Claussen CD, Hetzel J, Horger M.

Eur J Radiol. 2012 Jun;81(6):1315-20. doi: 10.1016/j.ejrad.2011.02.052. Epub 2011 Mar 21.

PMID:
21420818
26.

Moderate calcium channel dysfunction in adult mice with inducible cardiomyocyte-specific excision of the cacnb2 gene.

Meissner M, Weissgerber P, Londoño JE, Prenen J, Link S, Ruppenthal S, Molkentin JD, Lipp P, Nilius B, Freichel M, Flockerzi V.

J Biol Chem. 2011 May 6;286(18):15875-82. doi: 10.1074/jbc.M111.227819. Epub 2011 Feb 28.

27.

[Chronic brucellosis: a rare cause of septic loosening of arthroplasties with high risk of laboratory-acquired infections].

Wünschel M, Olszowski AM, Weissgerber P, Wülker N, Kluba T.

Z Orthop Unfall. 2011 Jan;149(1):33-6. doi: 10.1055/s-0030-1249851. Epub 2010 Apr 23. German.

PMID:
20419627
28.

Diversity and developmental expression of L-type calcium channel beta2 proteins and their influence on calcium current in murine heart.

Link S, Meissner M, Held B, Beck A, Weissgerber P, Freichel M, Flockerzi V.

J Biol Chem. 2009 Oct 30;284(44):30129-37. doi: 10.1074/jbc.M109.045583. Epub 2009 Sep 1.

29.

BK channels in innate immune functions of neutrophils and macrophages.

Essin K, Gollasch M, Rolle S, Weissgerber P, Sausbier M, Bohn E, Autenrieth IB, Ruth P, Luft FC, Nauseef WM, Kettritz R.

Blood. 2009 Feb 5;113(6):1326-31. doi: 10.1182/blood-2008-07-166660. Epub 2008 Dec 10.

30.

Increased IgE-dependent mast cell activation and anaphylactic responses in mice lacking the calcium-activated nonselective cation channel TRPM4.

Vennekens R, Olausson J, Meissner M, Bloch W, Mathar I, Philipp SE, Schmitz F, Weissgerber P, Nilius B, Flockerzi V, Freichel M.

Nat Immunol. 2007 Mar;8(3):312-20. Epub 2007 Feb 11.

PMID:
17293867
31.

Reduced cardiac L-type Ca2+ current in Ca(V)beta2-/- embryos impairs cardiac development and contraction with secondary defects in vascular maturation.

Weissgerber P, Held B, Bloch W, Kaestner L, Chien KR, Fleischmann BK, Lipp P, Flockerzi V, Freichel M.

Circ Res. 2006 Sep 29;99(7):749-57. Epub 2006 Aug 31.

PMID:
16946137
32.

Functional role of TRPC proteins in native systems: implications from knockout and knock-down studies.

Freichel M, Vennekens R, Olausson J, Stolz S, Philipp SE, Weissgerber P, Flockerzi V.

J Physiol. 2005 Aug 15;567(Pt 1):59-66. Epub 2005 Jun 23. Review.

33.

Removal of Ca2+ channel beta3 subunit enhances Ca2+ oscillation frequency and insulin exocytosis.

Berggren PO, Yang SN, Murakami M, Efanov AM, Uhles S, Köhler M, Moede T, Fernström A, Appelskog IB, Aspinwall CA, Zaitsev SV, Larsson O, de Vargas LM, Fecher-Trost C, Weissgerber P, Ludwig A, Leibiger B, Juntti-Berggren L, Barker CJ, Gromada J, Freichel M, Leibiger IB, Flockerzi V.

Cell. 2004 Oct 15;119(2):273-84.

34.

Functional role of TRPC proteins in vivo: lessons from TRPC-deficient mouse models.

Freichel M, Vennekens R, Olausson J, Hoffmann M, Müller C, Stolz S, Scheunemann J, Weissgerber P, Flockerzi V.

Biochem Biophys Res Commun. 2004 Oct 1;322(4):1352-8. Review.

PMID:
15336983
35.

Investigation of mechanisms involved in phagocytosis of Legionella pneumophila by human cells.

Weissgerber P, Faigle M, Northoff H, Neumeister B.

FEMS Microbiol Lett. 2003 Feb 28;219(2):173-9.

36.

Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4-/- mice.

Freichel M, Suh SH, Pfeifer A, Schweig U, Trost C, Weissgerber P, Biel M, Philipp S, Freise D, Droogmans G, Hofmann F, Flockerzi V, Nilius B.

Nat Cell Biol. 2001 Feb;3(2):121-7.

PMID:
11175743
37.

Mutations of calcium channel beta subunit genes in mice.

Freise D, Himmerkus N, Schroth G, Trost C, Weissgerber P, Freichel M, Flockerzi V.

Biol Chem. 1999 Jul-Aug;380(7-8):897-902. Review.

PMID:
10494839
38.

The inhibition of cancer cell stickiness by somatostatin.

Gastpar H, Zoltobrocki M, Weissgerber PW.

Res Exp Med (Berl). 1983;182(1):1-6.

PMID:
6134310
40.

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