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Probing the Selectivity of Monoamine Transporter Substrates by Means of Molecular Modeling.

Seddik A, Holy M, Weissensteiner R, Zdrazil B, Sitte HH, Ecker GF.

Mol Inform. 2013 Jun;32(5-6):409-413. Epub 2013 Jun 12. No abstract available.


Mutational analysis of the high-affinity zinc binding site validates a refined human dopamine transporter homology model.

Stockner T, Montgomery TR, Kudlacek O, Weissensteiner R, Ecker GF, Freissmuth M, Sitte HH.

PLoS Comput Biol. 2013;9(2):e1002909. doi: 10.1371/journal.pcbi.1002909. Epub 2013 Feb 21.


The high-affinity binding site for tricyclic antidepressants resides in the outer vestibule of the serotonin transporter.

Sarker S, Weissensteiner R, Steiner I, Sitte HH, Ecker GF, Freissmuth M, Sucic S.

Mol Pharmacol. 2010 Dec;78(6):1026-35. doi: 10.1124/mol.110.067538. Epub 2010 Sep 9.


The N terminus of monoamine transporters is a lever required for the action of amphetamines.

Sucic S, Dallinger S, Zdrazil B, Weissensteiner R, Jørgensen TN, Holy M, Kudlacek O, Seidel S, Cha JH, Gether U, Newman AH, Ecker GF, Freissmuth M, Sitte HH.

J Biol Chem. 2010 Apr 2;285(14):10924-38. doi: 10.1074/jbc.M109.083154. Epub 2010 Jan 29.

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