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Items: 30

1.

Characterizing valve dynamics in mice by high-resolution cine-MRI.

Weisell J, Ruotsalainen AK, Laakso H, Ylä-Herttuala E, Näpänkangas J, Levonen AL, Liimatainen T, Rysä J.

NMR Biomed. 2019 Aug;32(8):e4108. doi: 10.1002/nbm.4108. Epub 2019 May 21.

PMID:
31112347
2.

Increased mesenchymal podoplanin expression is associated with calcification in aortic valves.

Näpänkangas J, Ohtonen P, Ohukainen P, Weisell J, Väisänen T, Peltonen T, Taskinen P, Rysä J.

Cardiovasc Pathol. 2019 Mar - Apr;39:30-37. doi: 10.1016/j.carpath.2018.11.006. Epub 2018 Dec 7.

PMID:
30616084
3.

Stapled truncated orexin peptides as orexin receptor agonists.

Karhu L, Weisell J, Turunen PM, Leino TO, Pätsi H, Xhaard H, Kukkonen JP, Wallén EAA.

Peptides. 2018 Apr;102:54-60. doi: 10.1016/j.peptides.2018.02.004. Epub 2018 Feb 21.

4.

Triethylenetetramine modulates polyamine and energy metabolism and inhibits cancer cell proliferation.

Hyvönen MT, Ucal S, Pasanen M, Peräniemi S, Weisell J, Khomutov M, Khomutov AR, Vepsäläinen J, Alhonen L, Keinänen TA.

Biochem J. 2016 May 15;473(10):1433-41. doi: 10.1042/BCJ20160134. Epub 2016 Mar 21.

PMID:
27001865
5.

[Enantioselective Synthesis of (R)- and (S)-3-Methylspermidines].

Khomutov MA, Keinanen TA, Hyvonen MT, Weisell J, Vepsalainen J, Alhonen L, Kochetkov SN, Khomutov AR.

Bioorg Khim. 2015 Sep-Oct;41(5):612-8. Russian.

PMID:
26762100
6.

Two strategies for the synthesis of the biologically important ATP analogue ApppI, at a multi-milligram scale.

Weisell J, Vepsäläinen J, Turhanen PA.

Beilstein J Org Chem. 2015 Nov 13;11:2189-93. doi: 10.3762/bjoc.11.237. eCollection 2015.

7.

Structural requirements for bisphosphonate binding on hydroxyapatite: NMR study of bisphosphonate partial esters.

Puljula E, Turhanen P, Vepsäläinen J, Monteil M, Lecouvey M, Weisell J.

ACS Med Chem Lett. 2015 Feb 21;6(4):397-401. doi: 10.1021/ml5004603. eCollection 2015 Apr 9.

8.

Enantiomers of 3-methylspermidine selectively modulate deoxyhypusine synthesis and reveal important determinants for spermidine transport.

Hyvönen MT, Khomutov M, Petit M, Weisell J, Kochetkov SN, Alhonen L, Vepsäläinen J, Khomutov AR, Keinänen TA.

ACS Chem Biol. 2015 Jun 19;10(6):1417-24. doi: 10.1021/cb500938e. Epub 2015 Feb 27.

PMID:
25689365
9.

Replacement of the Disulfide Bridge in a KLK3-Stimulating Peptide Using Orthogonally Protected Building Blocks.

Meinander K, Pakkala M, Weisell J, Stenman UH, Koistinen H, Närvänen A, Wallén EA.

ACS Med Chem Lett. 2013 Dec 16;5(2):162-5. doi: 10.1021/ml400419g. eCollection 2014 Feb 13.

10.

Novel target for peptide-based imaging and treatment of brain tumors.

Hyvönen M, Enbäck J, Huhtala T, Lammi J, Sihto H, Weisell J, Joensuu H, Rosenthal-Aizman K, El-Andaloussi S, Langel U, Närvänen A, Bergers G, Laakkonen P.

Mol Cancer Ther. 2014 Apr;13(4):996-1007. doi: 10.1158/1535-7163.MCT-13-0684. Epub 2014 Feb 3.

11.

Hydroxylamine derivatives for regulation of spermine and spermidine metabolism.

Khomutov MA, Weisell J, Hyvönen M, Keinänen TA, Vepsäläinen J, Alhonen L, Khomutov AR, Kochetkov SN.

Biochemistry (Mosc). 2013 Dec;78(13):1431-46. doi: 10.1134/S0006297913130051. Review.

12.

Comprehensive strategy for proton chemical shift prediction: linear prediction with nonlinear corrections.

Laatikainen R, Hassinen T, Lehtivarjo J, Tiainen M, Jungman J, Tynkkynen T, Korhonen SP, Niemitz M, Poutiainen P, Jääskeläinen O, Väisänen T, Weisell J, Soininen P, Laatikainen P, Martonen H, Tuppurainen K.

J Chem Inf Model. 2014 Feb 24;54(2):419-30. doi: 10.1021/ci400648s. Epub 2014 Feb 11.

PMID:
24455975
13.

Firefly luciferase inhibitor-conjugated peptide quenches bioluminescence: a versatile tool for real time monitoring cellular uptake of biomolecules.

Poutiainen PK, Rönkkö T, Hinkkanen AE, Palvimo JJ, Närvänen A, Turhanen P, Laatikainen R, Weisell J, Pulkkinen JT.

Bioconjug Chem. 2014 Jan 15;25(1):4-10. doi: 10.1021/bc4003713. Epub 2013 Dec 19.

PMID:
24341748
14.

Peptide labelling strategies for imaging agents.

Huhtala T, Weisell J, Rytkönen J, Närvänen A.

Methods Mol Biol. 2014;1088:171-83. doi: 10.1007/978-1-62703-673-3_12.

PMID:
24146404
15.

SPECT/CT imaging of radiolabeled cubosomes and hexosomes for potential theranostic applications.

Nilsson C, Barrios-Lopez B, Kallinen A, Laurinmäki P, Butcher SJ, Raki M, Weisell J, Bergström K, Larsen SW, Østergaard J, Larsen C, Urtti A, Airaksinen AJ, Yaghmur A.

Biomaterials. 2013 Nov;34(33):8491-503. doi: 10.1016/j.biomaterials.2013.07.055. Epub 2013 Aug 7.

PMID:
23932247
16.

Charge deficient analogues of the natural polyamines.

Weisell J, Hyvönen MT, Alhonen L, Vepsäläinen J, Keinänen TA, Khomutov AR.

Curr Pharm Des. 2014;20(2):262-77. Review.

PMID:
23701551
17.

Spermidine promotes adipogenesis of 3T3-L1 cells by preventing interaction of ANP32 with HuR and PP2A.

Hyvönen MT, Koponen T, Weisell J, Pietilä M, Khomutov AR, Vepsäläinen J, Alhonen L, Keinänen TA.

Biochem J. 2013 Aug 1;453(3):467-74. doi: 10.1042/BJ20130263.

PMID:
23672317
18.

Preparation of mixed trialkyl alkylcarbonate derivatives of etidronic acid via an unusual route.

Turhanen PA, Weisell J, Vepsäläinen JJ.

Beilstein J Org Chem. 2012;8:2019-24. doi: 10.3762/bjoc.8.228. Epub 2012 Nov 20.

19.

Metabolism of triethylenetetramine and 1,12-diamino-3,6,9-triazadodecane by the spermidine/spermine-N(1)-acetyltransferase and thialysine acetyltransferase.

Hyvönen MT, Weisell J, Khomutov AR, Alhonen L, Vepsäläinen J, Keinänen TA.

Drug Metab Dispos. 2013 Jan;41(1):30-2. doi: 10.1124/dmd.112.047274. Epub 2012 Sep 28.

PMID:
23024204
20.

Complex N-acetylation of triethylenetetramine.

Cerrada-Gimenez M, Weisell J, Hyvönen MT, Park MH, Alhonen L, Vepsäläinen J, Keinänen TA.

Drug Metab Dispos. 2011 Dec;39(12):2242-9. doi: 10.1124/dmd.111.041798. Epub 2011 Aug 30.

21.

The use of novel C-methylated spermidine derivatives to investigate the regulation of polyamine metabolism.

Hyvönen MT, Keinänen TA, Khomutov M, Simonian A, Weisell J, Kochetkov SN, Vepsäläinen J, Alhonen L, Khomutov AR.

J Med Chem. 2011 Jul 14;54(13):4611-8. doi: 10.1021/jm200293r. Epub 2011 Jun 3.

PMID:
21639123
22.

Methylated polyamines as research tools.

Khomutov AR, Weisell J, Khomutov MA, Grigorenko NA, Simonian AR, Häkkinen MR, Keinänen TA, Hyvönen MT, Alhonen L, Kochetkov SN, Vepsäläinen J.

Methods Mol Biol. 2011;720:449-61. doi: 10.1007/978-1-61779-034-8_29.

PMID:
21318892
23.

Synthesis and biological characterization of novel charge-deficient spermine analogues.

Weisell J, Hyvönen MT, Häkkinen MR, Grigorenko NA, Pietilä M, Lampinen A, Kochetkov SN, Alhonen L, Vepsäläinen J, Keinänen TA, Khomutov AR.

J Med Chem. 2010 Aug 12;53(15):5738-48. doi: 10.1021/jm100439p.

PMID:
20684609
24.

Identification of IGFBP-3 fragments generated by KLK2 and prevention of fragmentation by KLK2-inhibiting peptides.

Hekim C, Riipi T, Weisell J, Närvänen A, Koistinen R, Stenman UH, Koistinen H.

Biol Chem. 2010 Apr;391(4):475-9. doi: 10.1515/BC.2010.039.

PMID:
20180640
25.

Identification of novel peptide inhibitors for human trypsins.

Wu P, Weisell J, Pakkala M, Peräkylä M, Zhu L, Koistinen R, Koivunen E, Stenman UH, Närvänen A, Koistinen H.

Biol Chem. 2010 Feb-Mar;391(2-3):283-93. doi: 10.1515/BC.2010.030.

PMID:
20128688
26.

Human urine and wood ash as plant nutrients for red beet (Beta vulgaris) cultivation: impacts on yield quality.

Pradhan SK, Holopainen JK, Weisell J, Heinonen-Tanski H.

J Agric Food Chem. 2010 Feb 10;58(3):2034-9. doi: 10.1021/jf9029157.

PMID:
20050665
27.

Novel convenient synthesis of biologically active esters of hydroxylamine.

Khomutov MA, Mandal S, Weisell J, Saxena N, Simonian AR, Vepsalainen J, Madhubala R, Kochetkov SN.

Amino Acids. 2010 Feb;38(2):509-17. doi: 10.1007/s00726-009-0410-0. Epub 2009 Dec 8.

PMID:
19997759
28.

Mimetics of the disulfide bridge between the N- and C-terminal cysteines of the KLK3-stimulating peptide B-2.

Pakkala M, Weisell J, Hekim C, Vepsäläinen J, Wallen EA, Stenman UH, Koistinen H, Närvänen A.

Amino Acids. 2010 Jun;39(1):233-42. doi: 10.1007/s00726-009-0433-6. Epub 2009 Dec 5.

PMID:
19967419
29.

Novel isosteric charge-deficient spermine analogue--1,12-diamino-3,6,9-triazadodecane: synthesis, pK(a) measurement and biological activity.

Weisell J, Hyvönen MT, Vepsäläinen J, Alhonen L, Keinänen TA, Khomutov AR, Soininen P.

Amino Acids. 2010 Feb;38(2):501-7. doi: 10.1007/s00726-009-0409-6. Epub 2009 Dec 2.

PMID:
19953281
30.

Activity and stability of human kallikrein-2-specific linear and cyclic peptide inhibitors.

Pakkala M, Hekim C, Soininen P, Leinonen J, Koistinen H, Weisell J, Stenman UH, Vepsäläinen J, Närvänen A.

J Pept Sci. 2007 May;13(5):348-53.

PMID:
17436344

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