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Items: 24


Liver Is a Generative Site for the B Cell Response to Ehrlichia muris.

Trivedi N, Weisel F, Smita S, Joachim S, Kader M, Radhakrishnan A, Clouser C, Rosenfeld AM, Chikina M, Vigneault F, Hershberg U, Ismail N, Shlomchik MJ.

Immunity. 2019 Nov 9. pii: S1074-7613(19)30448-0. doi: 10.1016/j.immuni.2019.10.004. [Epub ahead of print]


The AKT kinase signaling network is rewired by PTEN to control proximal BCR signaling in germinal center B cells.

Luo W, Hawse W, Conter L, Trivedi N, Weisel F, Wikenheiser D, Cattley RT, Shlomchik MJ.

Nat Immunol. 2019 Jun;20(6):736-746. doi: 10.1038/s41590-019-0376-3. Epub 2019 Apr 22.


Linking signaling and selection in the germinal center.

Shlomchik MJ, Luo W, Weisel F.

Immunol Rev. 2019 Mar;288(1):49-63. doi: 10.1111/imr.12744. Review.


B cell primary immune responses.

Shlomchik MJ, Weisel F.

Immunol Rev. 2019 Mar;288(1):5-9. doi: 10.1111/imr.12756. No abstract available.


B Cell Receptor and CD40 Signaling Are Rewired for Synergistic Induction of the c-Myc Transcription Factor in Germinal Center B Cells.

Luo W, Weisel F, Shlomchik MJ.

Immunity. 2018 Feb 20;48(2):313-326.e5. doi: 10.1016/j.immuni.2018.01.008.


Memory B Cells of Mice and Humans.

Weisel F, Shlomchik M.

Annu Rev Immunol. 2017 Apr 26;35:255-284. doi: 10.1146/annurev-immunol-041015-055531. Epub 2017 Jan 30. Review.


ZBTB32 Restricts the Duration of Memory B Cell Recall Responses.

Jash A, Wang Y, Weisel FJ, Scharer CD, Boss JM, Shlomchik MJ, Bhattacharya D.

J Immunol. 2016 Aug 15;197(4):1159-68. doi: 10.4049/jimmunol.1600882. Epub 2016 Jun 29.


A Temporal Switch in the Germinal Center Determines Differential Output of Memory B and Plasma Cells.

Weisel FJ, Zuccarino-Catania GV, Chikina M, Shlomchik MJ.

Immunity. 2016 Jan 19;44(1):116-130. doi: 10.1016/j.immuni.2015.12.004. Epub 2016 Jan 12.


CD80 and PD-L2 define functionally distinct memory B cell subsets that are independent of antibody isotype.

Zuccarino-Catania GV, Sadanand S, Weisel FJ, Tomayko MM, Meng H, Kleinstein SH, Good-Jacobson KL, Shlomchik MJ.

Nat Immunol. 2014 Jul;15(7):631-7. doi: 10.1038/ni.2914. Epub 2014 Jun 1.


Impact of S-adenosylmethionine decarboxylase 1 on pulmonary vascular remodeling.

Weisel FC, Kloepping C, Pichl A, Sydykov A, Kojonazarov B, Wilhelm J, Roth M, Ridge KM, Igarashi K, Nishimura K, Maison W, Wackendorff C, Klepetko W, Jaksch P, Ghofrani HA, Grimminger F, Seeger W, Schermuly RT, Weissmann N, Kwapiszewska G.

Circulation. 2014 Apr 8;129(14):1510-23. doi: 10.1161/CIRCULATIONAHA.113.006402. Epub 2014 Jan 27.


Sestrin-2, a repressor of PDGFRβ signalling, promotes cigarette-smoke-induced pulmonary emphysema in mice and is upregulated in individuals with COPD.

Heidler J, Fysikopoulos A, Wempe F, Seimetz M, Bangsow T, Tomasovic A, Veit F, Scheibe S, Pichl A, Weisel F, Lloyd KC, Jaksch P, Klepetko W, Weissmann N, von Melchner H.

Dis Model Mech. 2013 Nov;6(6):1378-87. doi: 10.1242/dmm.013482. Epub 2013 Aug 29.


Mitochondrial hyperpolarization in pulmonary vascular remodeling. Mitochondrial uncoupling protein deficiency as disease model.

Pak O, Sommer N, Hoeres T, Bakr A, Waisbrod S, Sydykov A, Haag D, Esfandiary A, Kojonazarov B, Veit F, Fuchs B, Weisel FC, Hecker M, Schermuly RT, Grimminger F, Ghofrani HA, Seeger W, Weissmann N.

Am J Respir Cell Mol Biol. 2013 Sep;49(3):358-67. doi: 10.1165/rcmb.2012-0361OC.


BDNF/TrkB signaling augments smooth muscle cell proliferation in pulmonary hypertension.

Kwapiszewska G, Chwalek K, Marsh LM, Wygrecka M, Wilhelm J, Best J, Egemnazarov B, Weisel FC, Osswald SL, Schermuly RT, Olschewski A, Seeger W, Weissmann N, Eickelberg O, Fink L.

Am J Pathol. 2012 Dec;181(6):2018-29. doi: 10.1016/j.ajpath.2012.08.028. Epub 2012 Oct 8.


Germinal center selection and the development of memory B and plasma cells.

Shlomchik MJ, Weisel F.

Immunol Rev. 2012 May;247(1):52-63. doi: 10.1111/j.1600-065X.2012.01124.x. Review.


Germinal centers.

Shlomchik MJ, Weisel F.

Immunol Rev. 2012 May;247(1):5-10. doi: 10.1111/j.1600-065X.2012.01125.x. No abstract available.


JAB1 is essential for B cell development and germinal center formation and inversely regulates Fas ligand and Bcl6 expression.

Sitte S, Gläsner J, Jellusova J, Weisel F, Panattoni M, Pardi R, Gessner A.

J Immunol. 2012 Mar 15;188(6):2677-86. doi: 10.4049/jimmunol.1101455. Epub 2012 Feb 10.


Inducible NOS inhibition reverses tobacco-smoke-induced emphysema and pulmonary hypertension in mice.

Seimetz M, Parajuli N, Pichl A, Veit F, Kwapiszewska G, Weisel FC, Milger K, Egemnazarov B, Turowska A, Fuchs B, Nikam S, Roth M, Sydykov A, Medebach T, Klepetko W, Jaksch P, Dumitrascu R, Garn H, Voswinckel R, Kostin S, Seeger W, Schermuly RT, Grimminger F, Ghofrani HA, Weissmann N.

Cell. 2011 Oct 14;147(2):293-305. doi: 10.1016/j.cell.2011.08.035.


B cell repertoire analysis identifies new antigenic domains on glycoprotein B of human cytomegalovirus which are target of neutralizing antibodies.

Pötzsch S, Spindler N, Wiegers AK, Fisch T, Rücker P, Sticht H, Grieb N, Baroti T, Weisel F, Stamminger T, Martin-Parras L, Mach M, Winkler TH.

PLoS Pathog. 2011 Aug;7(8):e1002172. doi: 10.1371/journal.ppat.1002172. Epub 2011 Aug 11.


A hypomorphic IgH-chain allele affects development of B-cell subsets and favours receptor editing.

Brenner S, Drewel D, Steinbart T, Weisel F, Härtel E, Pötzsch S, Welzel H, Brandl A, Yu P, Mudde GC, Schweizer A, Nitschke L, Winkler TH.

EMBO J. 2011 May 27;30(13):2705-18. doi: 10.1038/emboj.2011.168.


Unique requirements for reactivation of virus-specific memory B lymphocytes.

Weisel FJ, Appelt UK, Schneider AM, Horlitz JU, van Rooijen N, Korner H, Mach M, Winkler TH.

J Immunol. 2010 Oct 1;185(7):4011-21. doi: 10.4049/jimmunol.1001540. Epub 2010 Aug 25.


The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritis.

Neubert K, Meister S, Moser K, Weisel F, Maseda D, Amann K, Wiethe C, Winkler TH, Kalden JR, Manz RA, Voll RE.

Nat Med. 2008 Jul;14(7):748-55. doi: 10.1038/nm1763. Epub 2008 Jun 8.


Autoreactive B cells get activated in extrafollicular sites.

Weisel F, Wellmann U, Winkler TH.

Eur J Immunol. 2007 Dec;37(12):3330-3.


Protection from CMV infection in immunodeficient hosts by adoptive transfer of memory B cells.

Klenovsek K, Weisel F, Schneider A, Appelt U, Jonjic S, Messerle M, Bradel-Tretheway B, Winkler TH, Mach M.

Blood. 2007 Nov 1;110(9):3472-9. Epub 2007 Jul 26.


Siglec-G is a B1 cell-inhibitory receptor that controls expansion and calcium signaling of the B1 cell population.

Hoffmann A, Kerr S, Jellusova J, Zhang J, Weisel F, Wellmann U, Winkler TH, Kneitz B, Crocker PR, Nitschke L.

Nat Immunol. 2007 Jul;8(7):695-704. Epub 2007 Jun 17.


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