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Items: 1 to 50 of 114

1.

Retention of Native Quaternary Structure in Racemic Melittin Crystals.

Kurgan KW, Kleman AF, Bingman CA, Kreitler DF, Weisblum B, Forest KT, Gellman SH.

J Am Chem Soc. 2019 May 15;141(19):7704-7708. doi: 10.1021/jacs.9b02691. Epub 2019 May 6.

PMID:
31059253
2.

Inhibition of DNA replication in Staphylococcus aureus by tegaserod.

Lacriola CJ, Falk SP, Weisblum B.

J Antibiot (Tokyo). 2017 Jul;70(8):918-920. doi: 10.1038/ja.2017.65. Epub 2017 May 31. No abstract available.

PMID:
28559577
3.

Quasiracemate Crystal Structures of Magainin 2 Derivatives Support the Functional Significance of the Phenylalanine Zipper Motif.

Hayouka Z, Thomas NC, Mortenson DE, Satyshur KA, Weisblum B, Forest KT, Gellman SH.

J Am Chem Soc. 2015 Sep 23;137(37):11884-7. doi: 10.1021/jacs.5b07206. Epub 2015 Sep 10.

4.

Nylon-3 polymers active against drug-resistant Candida albicans biofilms.

Liu R, Chen X, Falk SP, Masters KS, Weisblum B, Gellman SH.

J Am Chem Soc. 2015 Feb 18;137(6):2183-6. doi: 10.1021/ja512567y. Epub 2015 Feb 4.

5.

Synthetic polymers active against Clostridium difficile vegetative cell growth and spore outgrowth.

Liu R, Suárez JM, Weisblum B, Gellman SH, McBride SM.

J Am Chem Soc. 2014 Oct 15;136(41):14498-504. doi: 10.1021/ja506798e. Epub 2014 Oct 3.

6.

Ternary nylon-3 copolymers as host-defense peptide mimics: beyond hydrophobic and cationic subunits.

Chakraborty S, Liu R, Hayouka Z, Chen X, Ehrhardt J, Lu Q, Burke E, Yang Y, Weisblum B, Wong GC, Masters KS, Gellman SH.

J Am Chem Soc. 2014 Oct 15;136(41):14530-5. doi: 10.1021/ja507576a. Epub 2014 Oct 1.

7.

Aptamer Displacement Screen for Flaviviral RNA Methyltransferase Inhibitors.

Falk SP, Weisblum B.

J Biomol Screen. 2014 Sep;19(8):1147-53. doi: 10.1177/1087057114533147. Epub 2014 May 2.

PMID:
24793430
8.

Structure-activity relationships among antifungal nylon-3 polymers: identification of materials active against drug-resistant strains of Candida albicans.

Liu R, Chen X, Falk SP, Mowery BP, Karlsson AJ, Weisblum B, Palecek SP, Masters KS, Gellman SH.

J Am Chem Soc. 2014 Mar 19;136(11):4333-42. doi: 10.1021/ja500036r. Epub 2014 Mar 7.

9.

Tuning the biological activity profile of antibacterial polymers via subunit substitution pattern.

Liu R, Chen X, Chakraborty S, Lemke JJ, Hayouka Z, Chow C, Welch RA, Weisblum B, Masters KS, Gellman SH.

J Am Chem Soc. 2014 Mar 19;136(11):4410-8. doi: 10.1021/ja500367u. Epub 2014 Mar 7.

10.

Effects of Cyclic vs. Acyclic Hydrophobic Subunits on the Chemical Structure and Biological Properties of Nylon-3 Co-Polymers.

Chakraborty S, Liu R, Lemke JJ, Hayouka Z, Welch RA, Weisblum B, Masters KS, Gellman SH.

ACS Macro Lett. 2013 Aug 20;2(8). doi: 10.1021/mz400239r.

11.

Evidence for phenylalanine zipper-mediated dimerization in the X-ray crystal structure of a magainin 2 analogue.

Hayouka Z, Mortenson DE, Kreitler DF, Weisblum B, Forest KT, Gellman SH.

J Am Chem Soc. 2013 Oct 23;135(42):15738-15741. doi: 10.1021/ja409082w. Epub 2013 Oct 8.

12.

Interplay among subunit identity, subunit proportion, chain length, and stereochemistry in the activity profile of sequence-random peptide mixtures.

Hayouka Z, Chakraborty S, Liu R, Boersma MD, Weisblum B, Gellman SH.

J Am Chem Soc. 2013 Aug 14;135(32):11748-51. doi: 10.1021/ja406231b. Epub 2013 Aug 5.

13.

West Nile virus methyltransferase domain interacts with protein kinase G.

Keating JA, Bhattacharya D, Lim PY, Falk S, Weisblum B, Bernard KA, Sharma M, Kuhn RJ, Striker R.

Virol J. 2013 Jul 22;10:242. doi: 10.1186/1743-422X-10-242.

14.

Nylon-3 polymers with selective antifungal activity.

Liu R, Chen X, Hayouka Z, Chakraborty S, Falk SP, Weisblum B, Masters KS, Gellman SH.

J Am Chem Soc. 2013 Apr 10;135(14):5270-3. doi: 10.1021/ja4006404. Epub 2013 Apr 2.

15.

Functionally Diverse Nylon-3 Copolymers from Readily Accessible β-Lactams.

Zhang J, Markiewicz MJ, Weisblum B, Stahl SS, Gellman SH.

ACS Macro Lett. 2012 Jun 19;1(6):714-717. Epub 2012 May 23.

16.

Phosphorylation of the Streptococcus pneumoniae cell wall biosynthesis enzyme MurC by a eukaryotic-like Ser/Thr kinase.

Falk SP, Weisblum B.

FEMS Microbiol Lett. 2013 Mar;340(1):19-23. doi: 10.1111/1574-6968.12067. Epub 2013 Jan 24.

17.

Screen for agents that induce autolysis in Bacillus subtilis.

Lacriola CJ, Falk SP, Weisblum B.

Antimicrob Agents Chemother. 2013 Jan;57(1):229-34. doi: 10.1128/AAC.00741-12. Epub 2012 Oct 22.

18.

C-terminal functionalization of nylon-3 polymers: effects of C-terminal groups on antibacterial and hemolytic activities.

Zhang J, Markiewicz MJ, Mowery BP, Weisblum B, Stahl SS, Gellman SH.

Biomacromolecules. 2012 Feb 13;13(2):323-31. doi: 10.1021/bm2013058. Epub 2011 Dec 29.

19.

Improved small-molecule macroarray platform for the rapid synthesis and discovery of antibacterial chalcones.

Stringer JR, Bowman MD, Weisblum B, Blackwell HE.

ACS Comb Sci. 2011 Mar 14;13(2):175-80. doi: 10.1021/co100053p. Epub 2011 Jan 6. Erratum in: ACS Comb Sci. 2011 May 9;13(3):345.

PMID:
21210707
20.

Screen for inducers of autolysis in Bacillus subtilis.

Falk SP, Noah JW, Weisblum B.

Antimicrob Agents Chemother. 2010 Sep;54(9):3723-9. doi: 10.1128/AAC.01597-09. Epub 2010 Jul 6.

21.

Structure-activity relationships among random nylon-3 copolymers that mimic antibacterial host-defense peptides.

Mowery BP, Lindner AH, Weisblum B, Stahl SS, Gellman SH.

J Am Chem Soc. 2009 Jul 22;131(28):9735-45. doi: 10.1021/ja901613g.

PMID:
19601684
22.

Phosphorylation of the RitR DNA-binding domain by a Ser-Thr phosphokinase: implications for global gene regulation in the streptococci.

Ulijasz AT, Falk SP, Weisblum B.

Mol Microbiol. 2009 Jan;71(2):382-90. doi: 10.1111/j.1365-2958.2008.06532.x. Epub 2008 Nov 21.

23.

Phosphorylation of yellow fever virus NS5 alters methyltransferase activity.

Bhattacharya D, Hoover S, Falk SP, Weisblum B, Vestling M, Striker R.

Virology. 2008 Oct 25;380(2):276-84. doi: 10.1016/j.virol.2008.07.013. Epub 2008 Aug 30.

24.

Screening for compounds that affect the interaction between bacterial two-component signal transduction response regulator protein and cognate promoter DNA.

Erickson MG, Ulijasz AT, Weisblum B.

Methods Mol Med. 2008;142:215-22. doi: 10.1007/978-1-59745-246-5_17.

PMID:
18437317
25.

Differential assay for high-throughput screening of antibacterial compounds.

Falk SP, Ulijasz AT, Weisblum B.

J Biomol Screen. 2007 Dec;12(8):1102-8.

PMID:
18087073
26.

Mimicry of antimicrobial host-defense peptides by random copolymers.

Mowery BP, Lee SE, Kissounko DA, Epand RF, Epand RM, Weisblum B, Stahl SS, Gellman SH.

J Am Chem Soc. 2007 Dec 19;129(50):15474-6. Epub 2007 Nov 23. No abstract available.

PMID:
18034491
27.

Interplay among folding, sequence, and lipophilicity in the antibacterial and hemolytic activities of alpha/beta-peptides.

Schmitt MA, Weisblum B, Gellman SH.

J Am Chem Soc. 2007 Jan 17;129(2):417-28.

PMID:
17212422
28.
29.

Macrolide resistance.

Weisblum B.

Drug Resist Updat. 1998 Mar;1(1):29-41.

PMID:
17092794
30.
31.

Antifungal activity from 14-helical beta-peptides.

Karlsson AJ, Pomerantz WC, Weisblum B, Gellman SH, Palecek SP.

J Am Chem Soc. 2006 Oct 4;128(39):12630-1.

PMID:
17002340
32.
34.
35.

Regulation of iron transport in Streptococcus pneumoniae by RitR, an orphan response regulator.

Ulijasz AT, Andes DR, Glasner JD, Weisblum B.

J Bacteriol. 2004 Dec;186(23):8123-36. Erratum in: J Bacteriol. 2006 Aug;188(16):6045.

36.
37.
38.

Affinity adsorbent based on combinatorial phage display peptides that bind alpha-cobratoxin.

Byeon WH, Weisblum B.

J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Jun 15;805(2):361-3.

PMID:
15135114
39.

Biocidal activity of polystyrenes that are cationic by virtue of protonation.

Gelman MA, Weisblum B, Lynn DM, Gellman SH.

Org Lett. 2004 Feb 19;6(4):557-60.

PMID:
14961622
40.
41.
42.

Mimicry of host-defense peptides by unnatural oligomers: antimicrobial beta-peptides.

Porter EA, Weisblum B, Gellman SH.

J Am Chem Soc. 2002 Jun 26;124(25):7324-30.

PMID:
12071741
43.

Tolerance of acyclic residues in the beta-peptide 12-helix: access to diverse side-chain arrays for biological applications.

LePlae PR, Fisk JD, Porter EA, Weisblum B, Gellman SH.

J Am Chem Soc. 2002 Jun 19;124(24):6820-1.

PMID:
12059191
44.

Peptide analogues of the VanS catalytic center inhibit VanR binding to its cognate promoter.

Ulijasz AT, Kay BK, Weisblum B.

Biochemistry. 2000 Sep 19;39(37):11417-24.

PMID:
10985787
45.

Modulation of erm methyltransferase activity by peptides derived from phage display.

Giannattasio RB, Weisblum B.

Antimicrob Agents Chemother. 2000 Jul;44(7):1961-3.

46.

Non-haemolytic beta-amino-acid oligomers.

Porter EA, Wang X, Lee HS, Weisblum B, Gellman SH.

Nature. 2000 Apr 6;404(6778):565. No abstract available. Erratum in: Nature 2000 May 18;405(6784):298.

PMID:
10766230
47.

Back to Camelot: defining the specific role of tRNA in protein synthesis.

Weisblum B.

Trends Biochem Sci. 1999 Jun;24(6):247-50. Review. No abstract available.

PMID:
10366855
48.

Dissecting the VanRS signal transduction pathway with specific inhibitors.

Ulijasz AT, Weisblum B.

J Bacteriol. 1999 Jan;181(2):627-31.

49.

Essential role of endogenously synthesized tylosin for induction of ermSF in Streptomyces fradiae.

Memili E, Weisblum B.

Antimicrob Agents Chemother. 1997 May;41(5):1203-5.

50.

Induction of ermSV by 16-membered-ring macrolide antibiotics.

Kamimiya S, Weisblum B.

Antimicrob Agents Chemother. 1997 Mar;41(3):530-4.

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